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The map label for this gene is trmD [H]

Identifier: 170079002

GI number: 170079002

Start: 2492663

End: 2493373

Strand: Direct

Name: trmD [H]

Synonym: SYNPCC7002_A2407

Alternate gene names: 170079002

Gene position: 2492663-2493373 (Clockwise)

Preceding gene: 170078999

Following gene: 170079003

Centisome position: 82.87

GC content: 54.43

Gene sequence:

>711_bases
ATGGCTTTACATTTCGATCTTGTGACCCTTTTTCCAGATTTTTTTACCTCGCCGCTCCAGTCCGGCCTCCTGGGAAAAGC
TTTAGGGAAAGGCATTGCCACCGTTAACTTCACCAACCCCAGGGATTTCACCACCGATAAACACCGGAGCGTTGATGATG
AACCCTATGGGGGCGGTGCGGGGATGTTATTAAAACCAGAACCCCTCTTCGCCGCAGTCGAGTCTTTACCCGTGCAACCT
AAGCGGGAAGTGATCTTGATGACGCCCCAGGGACAACGGCTCGACCAACAACTTTTGGCGGAATTAACCACCTATGACCA
GTTGGTTCTAATCTGCGGCCATTATGAAGGGGTCGATGAACGGGTGCGGGAGCATTTGGTGACCCGGGAAATTTCCTTGG
GCGATTTTGTCTTGACCTGTGGCGAAATTCCGGCGTTAACGTTGCTCAACGGCGTGATTCGCTTACTGCCGGGCACGGTG
GGCAAAGAAGCATCCCTGAAAGCCGATAGTTTCCAGGTGCCGCTGTTGGACTATCCGCAATATACGCGCCCGGCCAAGTT
TCGGGAGTGGGAAGTACCGGCGGTCTTGCGGTCTGGTAATCACCAAAAAATTGCGGAATGGCGTTTGTCCCAGCAAATCC
AACGCACCCAGGCCCGGCGGCCAGATCTGTGGGAAGCGTGGCAGGCTTCCGAGGGGGAGGTTCAAGAATGA

Upstream 100 bases:

>100_bases
GAAAAATCCCCACAATTATTGCATAGTCCTTGTCATTCTCAAATTAGCTGATTATTCTTTTTTAGGTCAAAAAACCATCA
CTTTCACTCCCCCTTTTTCT

Downstream 100 bases:

>100_bases
TTGTGAGTCTTTATCACCGATTATTGGGCATGATGTTGGCGATCGCCAGCCAATTTGAGGGCCATGACACCTCGCCCCTG
CTCCTTTCAATGCAGGCCCT

Product: tRNA (guanine-N(1)-)-methyltransferase

Products: NA

Alternate protein names: M1G-methyltransferase; tRNA [GM37] methyltransferase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MALHFDLVTLFPDFFTSPLQSGLLGKALGKGIATVNFTNPRDFTTDKHRSVDDEPYGGGAGMLLKPEPLFAAVESLPVQP
KREVILMTPQGQRLDQQLLAELTTYDQLVLICGHYEGVDERVREHLVTREISLGDFVLTCGEIPALTLLNGVIRLLPGTV
GKEASLKADSFQVPLLDYPQYTRPAKFREWEVPAVLRSGNHQKIAEWRLSQQIQRTQARRPDLWEAWQASEGEVQE

Sequences:

>Translated_236_residues
MALHFDLVTLFPDFFTSPLQSGLLGKALGKGIATVNFTNPRDFTTDKHRSVDDEPYGGGAGMLLKPEPLFAAVESLPVQP
KREVILMTPQGQRLDQQLLAELTTYDQLVLICGHYEGVDERVREHLVTREISLGDFVLTCGEIPALTLLNGVIRLLPGTV
GKEASLKADSFQVPLLDYPQYTRPAKFREWEVPAVLRSGNHQKIAEWRLSQQIQRTQARRPDLWEAWQASEGEVQE
>Mature_235_residues
ALHFDLVTLFPDFFTSPLQSGLLGKALGKGIATVNFTNPRDFTTDKHRSVDDEPYGGGAGMLLKPEPLFAAVESLPVQPK
REVILMTPQGQRLDQQLLAELTTYDQLVLICGHYEGVDERVREHLVTREISLGDFVLTCGEIPALTLLNGVIRLLPGTVG
KEASLKADSFQVPLLDYPQYTRPAKFREWEVPAVLRSGNHQKIAEWRLSQQIQRTQARRPDLWEAWQASEGEVQE

Specific function: Specifically methylates guanosine-37 in various tRNAs [H]

COG id: COG0336

COG function: function code J; tRNA-(guanine-N1)-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase trmD family [H]

Homologues:

Organism=Escherichia coli, GI1788959, Length=227, Percent_Identity=45.8149779735683, Blast_Score=210, Evalue=8e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016009
- InterPro:   IPR002649
- InterPro:   IPR023148 [H]

Pfam domain/function: PF01746 tRNA_m1G_MT [H]

EC number: =2.1.1.31 [H]

Molecular weight: Translated: 26477; Mature: 26345

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHFDLVTLFPDFFTSPLQSGLLGKALGKGIATVNFTNPRDFTTDKHRSVDDEPYGGGA
CEEEHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GMLLKPEPLFAAVESLPVQPKREVILMTPQGQRLDQQLLAELTTYDQLVLICGHYEGVDE
CCEECCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHH
RVREHLVTREISLGDFVLTCGEIPALTLLNGVIRLLPGTVGKEASLKADSFQVPLLDYPQ
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
YTRPAKFREWEVPAVLRSGNHQKIAEWRLSQQIQRTQARRPDLWEAWQASEGEVQE
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALHFDLVTLFPDFFTSPLQSGLLGKALGKGIATVNFTNPRDFTTDKHRSVDDEPYGGGA
EEEHHHHHHHHHHHHHHHHHCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
GMLLKPEPLFAAVESLPVQPKREVILMTPQGQRLDQQLLAELTTYDQLVLICGHYEGVDE
CCEECCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHH
RVREHLVTREISLGDFVLTCGEIPALTLLNGVIRLLPGTVGKEASLKADSFQVPLLDYPQ
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
YTRPAKFREWEVPAVLRSGNHQKIAEWRLSQQIQRTQARRPDLWEAWQASEGEVQE
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA