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The map label for this gene is napA [H]

Identifier: 170078967

GI number: 170078967

Start: 2454712

End: 2456130

Strand: Direct

Name: napA [H]

Synonym: SYNPCC7002_A2372

Alternate gene names: 170078967

Gene position: 2454712-2456130 (Clockwise)

Preceding gene: 170078966

Following gene: 170078968

Centisome position: 81.6

GC content: 53.0

Gene sequence:

>1419_bases
ATGCTAAGTCCCACAATCTTTTCTGGTAGTCTGCCAGGATTGACGGATTTCGTTCCTTCCCTGTCCCTGGCGACAACCCC
GGAAGCTGACTATGGTTCATTTGTTTTAACCGGCGTTTTAATGACCCTGGTCGTGATCTATGCCATGAGTAAGTTGGGGG
GAGAACTCTCCAAACGAGTCGGCTTACCTCCTGTATTAGGGGAACTGGTCGGAGGTGTTCTAGTCGGGGTCTCGGCGCTC
CACCTCATCGTCTTTCCGGAAACAGGGGCCACGGCTGCTGACTCAAGTTTAATGCTGTTTTTGCAGCAGCTTGGTGGTTT
AGATGGCACTGCCCTTGAGCATATTTTTGCCAGCCAAAGCGAAGTGATCTCGGTATTGGCAGAGCTTGGGGTCATCGTGC
TGTTATTTGAGATTGGCCTCGAATCAGACCTCCGAGAGCTGAGTAAAGTGGGTTCCCAGGCTGCGGTGGTCGCGATTGTC
GGGGTGGTGGCACCTTTCCTCTTGGGGACGGTGGGCCTAGTGACGTTGTTCCATACGCCGATTATCCCTGCTATTTTTGC
GGGGGCCGCCCTCACGGCCACGAGTATTGGCATTACCTCGAAGGTACTGTCGGACTTGGGTCAGCTAAAGTCCACCGAAG
GCAAAATTATCGTTGGTGCGGCGGTGATTGACGATGTGCTGGGGATTATTGTTTTAGCGGTCGTCGCGAGTTTGGCCAAG
ACCGGGGAAGTGGATCTCCTGAATGTGGTCTATCTGATTATTGGGGCCAGTGCTTTTCTGTTGGGTTCGATTCTGCTCGG
TAAATTCTTTAACCAAGGTTTTGAGGCGATCGCCGCCAAACTAAAAACCCGGGGCGCGCTGTTGATTCCGGCCTTTGCCT
TTGCGTTGGTGATGGCGATTATTGCGAACCTCATCCATTTAGAAGCCATTTTAGGGGCCTTCGCAGCGGGTCTTGTGTTG
GATGAAACGGATCTCCGTAAAGAGTTAGACCGTCAGGTGATGCCCATTGCCGACTTTTTAGTGCCGATCTTTTTTGTAAC
TGTGGGAGCAAAAGCAGACCTTGGTGTTCTGAACCCCTTCGAGTCTGCCAACCGCGCCGGATTAGTGATTGCTGCGTTCC
TCATCGTTGTGGCGATTGTCGGGAAGGTAATCACGGGCTGGGCCGTCTTTGGTCAACCGGGGGTGAATCGCTTGGCCATT
GGTTTTGGCATGATTCCCCGGGGAGAAGTGGGCCTCGTTTTTGCGGGCATTGGTTCTGCTAGTGGTGTGTTAGATAAGCC
CCTAGAAGCAGCCATCATTGTGATGGTGATCTTGACCACTTTCTTGGCACCGCCGCTCCTCCAGGCTGTTTTAAATAAGC
CCCAGGATCCGGATGTGCCTGCCGACCGGGAAGCCCTTGAGAAAAGTTTGTCGGTGTAG

Upstream 100 bases:

>100_bases
GCCCTCTCCAGGTTCGATGCAACCTATCCCTTTTCCCTTTTGTCCCATCCCTGCAATATTTGCGATCGCTTTTTACCACA
ACGTTTGAGGCAAAAATTCT

Downstream 100 bases:

>100_bases
GAAATCATTACTGGGGGATTGTCATCAGGGACATCCCCCACTCGGACGGAGGGAATTCAGCCATGTCGATGTCTATGCTC
GAAGCCTGTGTGTTTGCAGT

Product: Sodium/hydrogen exchanger family protein (Na/H antiporter)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MLSPTIFSGSLPGLTDFVPSLSLATTPEADYGSFVLTGVLMTLVVIYAMSKLGGELSKRVGLPPVLGELVGGVLVGVSAL
HLIVFPETGATAADSSLMLFLQQLGGLDGTALEHIFASQSEVISVLAELGVIVLLFEIGLESDLRELSKVGSQAAVVAIV
GVVAPFLLGTVGLVTLFHTPIIPAIFAGAALTATSIGITSKVLSDLGQLKSTEGKIIVGAAVIDDVLGIIVLAVVASLAK
TGEVDLLNVVYLIIGASAFLLGSILLGKFFNQGFEAIAAKLKTRGALLIPAFAFALVMAIIANLIHLEAILGAFAAGLVL
DETDLRKELDRQVMPIADFLVPIFFVTVGAKADLGVLNPFESANRAGLVIAAFLIVVAIVGKVITGWAVFGQPGVNRLAI
GFGMIPRGEVGLVFAGIGSASGVLDKPLEAAIIVMVILTTFLAPPLLQAVLNKPQDPDVPADREALEKSLSV

Sequences:

>Translated_472_residues
MLSPTIFSGSLPGLTDFVPSLSLATTPEADYGSFVLTGVLMTLVVIYAMSKLGGELSKRVGLPPVLGELVGGVLVGVSAL
HLIVFPETGATAADSSLMLFLQQLGGLDGTALEHIFASQSEVISVLAELGVIVLLFEIGLESDLRELSKVGSQAAVVAIV
GVVAPFLLGTVGLVTLFHTPIIPAIFAGAALTATSIGITSKVLSDLGQLKSTEGKIIVGAAVIDDVLGIIVLAVVASLAK
TGEVDLLNVVYLIIGASAFLLGSILLGKFFNQGFEAIAAKLKTRGALLIPAFAFALVMAIIANLIHLEAILGAFAAGLVL
DETDLRKELDRQVMPIADFLVPIFFVTVGAKADLGVLNPFESANRAGLVIAAFLIVVAIVGKVITGWAVFGQPGVNRLAI
GFGMIPRGEVGLVFAGIGSASGVLDKPLEAAIIVMVILTTFLAPPLLQAVLNKPQDPDVPADREALEKSLSV
>Mature_472_residues
MLSPTIFSGSLPGLTDFVPSLSLATTPEADYGSFVLTGVLMTLVVIYAMSKLGGELSKRVGLPPVLGELVGGVLVGVSAL
HLIVFPETGATAADSSLMLFLQQLGGLDGTALEHIFASQSEVISVLAELGVIVLLFEIGLESDLRELSKVGSQAAVVAIV
GVVAPFLLGTVGLVTLFHTPIIPAIFAGAALTATSIGITSKVLSDLGQLKSTEGKIIVGAAVIDDVLGIIVLAVVASLAK
TGEVDLLNVVYLIIGASAFLLGSILLGKFFNQGFEAIAAKLKTRGALLIPAFAFALVMAIIANLIHLEAILGAFAAGLVL
DETDLRKELDRQVMPIADFLVPIFFVTVGAKADLGVLNPFESANRAGLVIAAFLIVVAIVGKVITGWAVFGQPGVNRLAI
GFGMIPRGEVGLVFAGIGSASGVLDKPLEAAIIVMVILTTFLAPPLLQAVLNKPQDPDVPADREALEKSLSV

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=349, Percent_Identity=26.9340974212034, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786232, Length=420, Percent_Identity=23.5714285714286, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322367, Length=370, Percent_Identity=26.2162162162162, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 48611; Mature: 48611

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSPTIFSGSLPGLTDFVPSLSLATTPEADYGSFVLTGVLMTLVVIYAMSKLGGELSKRV
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPPVLGELVGGVLVGVSALHLIVFPETGATAADSSLMLFLQQLGGLDGTALEHIFASQS
CCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
EVISVLAELGVIVLLFEIGLESDLRELSKVGSQAAVVAIVGVVAPFLLGTVGLVTLFHTP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIPAIFAGAALTATSIGITSKVLSDLGQLKSTEGKIIVGAAVIDDVLGIIVLAVVASLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
TGEVDLLNVVYLIIGASAFLLGSILLGKFFNQGFEAIAAKLKTRGALLIPAFAFALVMAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IANLIHLEAILGAFAAGLVLDETDLRKELDRQVMPIADFLVPIFFVTVGAKADLGVLNPF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ESANRAGLVIAAFLIVVAIVGKVITGWAVFGQPGVNRLAIGFGMIPRGEVGLVFAGIGSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEEECCCC
SGVLDKPLEAAIIVMVILTTFLAPPLLQAVLNKPQDPDVPADREALEKSLSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLSPTIFSGSLPGLTDFVPSLSLATTPEADYGSFVLTGVLMTLVVIYAMSKLGGELSKRV
CCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPPVLGELVGGVLVGVSALHLIVFPETGATAADSSLMLFLQQLGGLDGTALEHIFASQS
CCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
EVISVLAELGVIVLLFEIGLESDLRELSKVGSQAAVVAIVGVVAPFLLGTVGLVTLFHTP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIPAIFAGAALTATSIGITSKVLSDLGQLKSTEGKIIVGAAVIDDVLGIIVLAVVASLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
TGEVDLLNVVYLIIGASAFLLGSILLGKFFNQGFEAIAAKLKTRGALLIPAFAFALVMAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IANLIHLEAILGAFAAGLVLDETDLRKELDRQVMPIADFLVPIFFVTVGAKADLGVLNPF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ESANRAGLVIAAFLIVVAIVGKVITGWAVFGQPGVNRLAIGFGMIPRGEVGLVFAGIGSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEEECCCC
SGVLDKPLEAAIIVMVILTTFLAPPLLQAVLNKPQDPDVPADREALEKSLSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]