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The map label for this gene is map [C]

Identifier: 170078938

GI number: 170078938

Start: 2421202

End: 2422044

Strand: Direct

Name: map [C]

Synonym: SYNPCC7002_A2343

Alternate gene names: 170078938

Gene position: 2421202-2422044 (Clockwise)

Preceding gene: 170078936

Following gene: 170078939

Centisome position: 80.49

GC content: 50.65

Gene sequence:

>843_bases
TTGAAACAGTTACTCAACCTCCTAATTCCCGAACCTAAAAAAGCCCAAGTGGGCCTCCCCCGCCGCCGTAAAAAAAGCAA
AGTTAAAATTAAGACCGCCGCTGAAATTGCAATTATGCGACAATCGGCGCGGATTGTGGCGACCGTCCTCAAGGAAATGA
GTGAGATTATCAAGCCAGGGATGACGACCCTCGAAGTGGATACCTATGCTGAACAGCGGATCCGAGAATTAGGCGCAACG
CCCAGCTTTAAAGGATATTACGGTTTTCCCGGTTCCATCTGCATCTCGATCAACGATGAAGTTGTCCATGGCATTCCCCG
GGCCGATAAACGCATCCACCAAGGGGACATCGTGAAAGTCGATACGGGTGCATTATTTAATGGTTATCATGGCGATTCTT
GTATTACCGTCGGCGTTGGCAAAAAGATCAAACCGGAGGCTAAACGATTAATGCAAGCGGCTGAAGAAGCCCTCTATAAA
GGGATTGAACAAGTAAAAGCAGGCAATACGCTCCTGGATATTGCTGGGGCCGTCGAAGACCATGTCCACAGCTATGGCTA
CCAGGTGGTGGAAGACTTTACGGGCCATGGGGTCGGTCAAGCGCTCCACGAGGAACCATCGGTGTTTAATTTCCGCACCC
GCGACCTGCCCAATGTCGTCCTAGAAGCGGGCATGGTGCTGGCCATTGAACCGATTGTCAATGCCAAAACAAAAGAAACC
ATCACCCTCGAAGATAAATGGACGGTGATCACCCCCGATAAGTCCCTGTCGGCCCAGTTTGAACATACGGTGCTGGTGAC
GGAAACGGGCTACGAGATTCTCACGGATCGCAATCTGGTGTAA

Upstream 100 bases:

>100_bases
ATCGCCAAGATTTTTACCATGCCCGGCGCATTGTCGCTGATCTCGATCCCGCCGCCGAAATAATTGCCCAATCTGCCATT
GATTTCCTCAAGGTACTCCA

Downstream 100 bases:

>100_bases
TTACCCAAAAAGCGAAAAAACTCAATACAATGGGCGGCAATGTGTGTGGAATGTTGGTATGTTTTTTCCCTTCTTTGTTG
CCCAAGCGCCGCCCCCAGTT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKQLLNLLIPEPKKAQVGLPRRRKKSKVKIKTAAEIAIMRQSARIVATVLKEMSEIIKPGMTTLEVDTYAEQRIRELGAT
PSFKGYYGFPGSICISINDEVVHGIPRADKRIHQGDIVKVDTGALFNGYHGDSCITVGVGKKIKPEAKRLMQAAEEALYK
GIEQVKAGNTLLDIAGAVEDHVHSYGYQVVEDFTGHGVGQALHEEPSVFNFRTRDLPNVVLEAGMVLAIEPIVNAKTKET
ITLEDKWTVITPDKSLSAQFEHTVLVTETGYEILTDRNLV

Sequences:

>Translated_280_residues
MKQLLNLLIPEPKKAQVGLPRRRKKSKVKIKTAAEIAIMRQSARIVATVLKEMSEIIKPGMTTLEVDTYAEQRIRELGAT
PSFKGYYGFPGSICISINDEVVHGIPRADKRIHQGDIVKVDTGALFNGYHGDSCITVGVGKKIKPEAKRLMQAAEEALYK
GIEQVKAGNTLLDIAGAVEDHVHSYGYQVVEDFTGHGVGQALHEEPSVFNFRTRDLPNVVLEAGMVLAIEPIVNAKTKET
ITLEDKWTVITPDKSLSAQFEHTVLVTETGYEILTDRNLV
>Mature_280_residues
MKQLLNLLIPEPKKAQVGLPRRRKKSKVKIKTAAEIAIMRQSARIVATVLKEMSEIIKPGMTTLEVDTYAEQRIRELGAT
PSFKGYYGFPGSICISINDEVVHGIPRADKRIHQGDIVKVDTGALFNGYHGDSCITVGVGKKIKPEAKRLMQAAEEALYK
GIEQVKAGNTLLDIAGAVEDHVHSYGYQVVEDFTGHGVGQALHEEPSVFNFRTRDLPNVVLEAGMVLAIEPIVNAKTKET
ITLEDKWTVITPDKSLSAQFEHTVLVTETGYEILTDRNLV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=253, Percent_Identity=37.5494071146245, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI40385867, Length=250, Percent_Identity=36.4, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=43.4262948207171, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1788728, Length=229, Percent_Identity=26.2008733624454, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=276, Percent_Identity=35.1449275362319, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323273, Length=275, Percent_Identity=37.4545454545455, Blast_Score=181, Evalue=8e-47,
Organism=Drosophila melanogaster, GI24583427, Length=267, Percent_Identity=35.5805243445693, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21355531, Length=255, Percent_Identity=35.6862745098039, Blast_Score=161, Evalue=5e-40,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30903; Mature: 30903

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLLNLLIPEPKKAQVGLPRRRKKSKVKIKTAAEIAIMRQSARIVATVLKEMSEIIKPG
CHHHHHHHCCCCCCCCCCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MTTLEVDTYAEQRIRELGATPSFKGYYGFPGSICISINDEVVHGIPRADKRIHQGDIVKV
CEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHHCCCCHHHHCCCCCEEEE
DTGALFNGYHGDSCITVGVGKKIKPEAKRLMQAAEEALYKGIEQVKAGNTLLDIAGAVED
ECCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HVHSYGYQVVEDFTGHGVGQALHEEPSVFNFRTRDLPNVVLEAGMVLAIEPIVNAKTKET
HHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCE
ITLEDKWTVITPDKSLSAQFEHTVLVTETGYEILTDRNLV
EEECCCEEEECCCCCCCCCEEEEEEEEECCCEEECCCCCC
>Mature Secondary Structure
MKQLLNLLIPEPKKAQVGLPRRRKKSKVKIKTAAEIAIMRQSARIVATVLKEMSEIIKPG
CHHHHHHHCCCCCCCCCCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MTTLEVDTYAEQRIRELGATPSFKGYYGFPGSICISINDEVVHGIPRADKRIHQGDIVKV
CEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHHCCCCHHHHCCCCCEEEE
DTGALFNGYHGDSCITVGVGKKIKPEAKRLMQAAEEALYKGIEQVKAGNTLLDIAGAVED
ECCCEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HVHSYGYQVVEDFTGHGVGQALHEEPSVFNFRTRDLPNVVLEAGMVLAIEPIVNAKTKET
HHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCE
ITLEDKWTVITPDKSLSAQFEHTVLVTETGYEILTDRNLV
EEECCCEEEECCCCCCCCCEEEEEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]