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The map label for this gene is tuaD [H]

Identifier: 170078935

GI number: 170078935

Start: 2416906

End: 2418255

Strand: Direct

Name: tuaD [H]

Synonym: SYNPCC7002_A2340

Alternate gene names: 170078935

Gene position: 2416906-2418255 (Clockwise)

Preceding gene: 170078934

Following gene: 170078936

Centisome position: 80.35

GC content: 49.93

Gene sequence:

>1350_bases
ATGAAAGTTTGTGTAATTGGAACGGGTTACGTGGGCCTGGTCACAGGGGTTTGCCTGGCGCACATGGGCCATGATGTCAT
CTGCATCGACAACAATGAGCAGAAAATCAAGCTCATGCAGGCGGGGCGATCGCCGATTTATGAACCCGGTCTAGCGGAAC
TGATGCAGGAAGAAATGGCCACCGGACGCTTGCAATTTAGTACAGACCTCAGTTTTGGCGTCAATCATGGGGAAATTCTG
TTTATCGCTGTGGGTACCCCAGCCTTGCCGACGGGGGAAAGCGACACCCGCTATGTGGAGGCCGTGGCGAAGGGTATTGG
TGAACATTTGCCCGCCGATAGTTACAAAGTAATTGTTAACAAATCAACGGTTCCGATTGGGTCGGGGGACTGGGTGCGGA
TGATTGTCCTCGATGGAGTCAAACAGAAGCAAAACGGCCATACGGTGCAGTTTGATGTGGTCAGTAACCCCGAATTTCTC
CGGGAAGGGTCAGCAATTTTCGATACTTTTAACCCCGATCGCATTGTTTTAGGTAGTAGCAACTCCAAGGCGATCGCCTT
GATGAAACAGCTTTATGATCCCCTCATCCAAGGGCAATTTAGCGCGCCAGAACACCTCAAACCGATTCCGGTGGTGGAAA
CTGACCTAAATTCCGCCGAAATGATTAAATATGCTGCCAATGCTTTCCTTGCAACGAAAATTAGCTTTATTAATGAAGTG
GCGAATGTGTGCGATCGCGTGGGGGCAGACATTCTCCAGGTGGCGAAGGGCATCGGCCTCGATAGTCGCATTGGTAATAA
ATTTCTCCAGGCAGGCTTGGGTTGGGGTGGTTCCTGTTTCCCGAAAGACGTGGCCGCTTTAGTACACACTGCCGAAGATT
ATGGCTACCAAGCGCAACTCCTCGAAGCGGCAGTGACGGTGAATAATCGGCAAAAATTAATCGTCGTCGAAAAGCTTCAA
CAGGAATTGAAAATTCTTAAGGGGAAAACCATTGGTTTGTTGGGGTTAACCTTCAAGCCAGACACCGATGATATGCGTGA
TGCTCCATCCCTGAAGCTGATTGCAGAACTTAATCGTCTAGGAGCACGGGTGAAAGCCTATGACCCGATTGTGTCCCAAA
ATGGCATTAGTCAAGGTCTTTCGGGCGTCCTGATTGAAAATAGCCCAGAAATGTTAGCAGATACCTGTGATGCTCTGGTT
TTAGTCACGGACTGGCAAGAATTTTTGCACCTCGACTATGGACAGTTAGGCGATCGCCTCCAAAATCGGTTGATCATCGA
TGGCCGGAATTTCCTCGACCGAGACGCCCTCGAAGCCCTGGGGTTCCGCTATGTGGGCATTGGCCATTAA

Upstream 100 bases:

>100_bases
GCCCCTCAAGGTGGGCTTAGAAAAAACGATCGCCTATTTCCGCGATCGCCTCGCAGAATAACTAACGGACAACAACACGA
GAAATTCACTAGAAATTGCG

Downstream 100 bases:

>100_bases
GTGTTTTAAGCTTCAGAGCCTGTTTATAAAGAAAAAATTAAATCAAGACTGGATAAGGGATTTGGCTTCATTCGTCGCCA
TGTAGATCAAGCGTCCTACA

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH; Teichuronic acid biosynthesis protein tuaD [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKVCVIGTGYVGLVTGVCLAHMGHDVICIDNNEQKIKLMQAGRSPIYEPGLAELMQEEMATGRLQFSTDLSFGVNHGEIL
FIAVGTPALPTGESDTRYVEAVAKGIGEHLPADSYKVIVNKSTVPIGSGDWVRMIVLDGVKQKQNGHTVQFDVVSNPEFL
REGSAIFDTFNPDRIVLGSSNSKAIALMKQLYDPLIQGQFSAPEHLKPIPVVETDLNSAEMIKYAANAFLATKISFINEV
ANVCDRVGADILQVAKGIGLDSRIGNKFLQAGLGWGGSCFPKDVAALVHTAEDYGYQAQLLEAAVTVNNRQKLIVVEKLQ
QELKILKGKTIGLLGLTFKPDTDDMRDAPSLKLIAELNRLGARVKAYDPIVSQNGISQGLSGVLIENSPEMLADTCDALV
LVTDWQEFLHLDYGQLGDRLQNRLIIDGRNFLDRDALEALGFRYVGIGH

Sequences:

>Translated_449_residues
MKVCVIGTGYVGLVTGVCLAHMGHDVICIDNNEQKIKLMQAGRSPIYEPGLAELMQEEMATGRLQFSTDLSFGVNHGEIL
FIAVGTPALPTGESDTRYVEAVAKGIGEHLPADSYKVIVNKSTVPIGSGDWVRMIVLDGVKQKQNGHTVQFDVVSNPEFL
REGSAIFDTFNPDRIVLGSSNSKAIALMKQLYDPLIQGQFSAPEHLKPIPVVETDLNSAEMIKYAANAFLATKISFINEV
ANVCDRVGADILQVAKGIGLDSRIGNKFLQAGLGWGGSCFPKDVAALVHTAEDYGYQAQLLEAAVTVNNRQKLIVVEKLQ
QELKILKGKTIGLLGLTFKPDTDDMRDAPSLKLIAELNRLGARVKAYDPIVSQNGISQGLSGVLIENSPEMLADTCDALV
LVTDWQEFLHLDYGQLGDRLQNRLIIDGRNFLDRDALEALGFRYVGIGH
>Mature_449_residues
MKVCVIGTGYVGLVTGVCLAHMGHDVICIDNNEQKIKLMQAGRSPIYEPGLAELMQEEMATGRLQFSTDLSFGVNHGEIL
FIAVGTPALPTGESDTRYVEAVAKGIGEHLPADSYKVIVNKSTVPIGSGDWVRMIVLDGVKQKQNGHTVQFDVVSNPEFL
REGSAIFDTFNPDRIVLGSSNSKAIALMKQLYDPLIQGQFSAPEHLKPIPVVETDLNSAEMIKYAANAFLATKISFINEV
ANVCDRVGADILQVAKGIGLDSRIGNKFLQAGLGWGGSCFPKDVAALVHTAEDYGYQAQLLEAAVTVNNRQKLIVVEKLQ
QELKILKGKTIGLLGLTFKPDTDDMRDAPSLKLIAELNRLGARVKAYDPIVSQNGISQGLSGVLIENSPEMLADTCDALV
LVTDWQEFLHLDYGQLGDRLQNRLIIDGRNFLDRDALEALGFRYVGIGH

Specific function: Catalyzes the conversion of UDP-glucose into UDP- glucuronate, one of the precursors of teichuronic acid [H]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=477, Percent_Identity=35.2201257861635, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI296040438, Length=378, Percent_Identity=34.9206349206349, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI296040443, Length=323, Percent_Identity=35.9133126934984, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1788340, Length=382, Percent_Identity=27.7486910994764, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI48994968, Length=442, Percent_Identity=26.0180995475113, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=473, Percent_Identity=35.5179704016913, Blast_Score=270, Evalue=8e-73,
Organism=Drosophila melanogaster, GI17136908, Length=476, Percent_Identity=34.6638655462185, Blast_Score=262, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48822; Mature: 48822

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVCVIGTGYVGLVTGVCLAHMGHDVICIDNNEQKIKLMQAGRSPIYEPGLAELMQEEMA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
TGRLQFSTDLSFGVNHGEILFIAVGTPALPTGESDTRYVEAVAKGIGEHLPADSYKVIVN
CCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
KSTVPIGSGDWVRMIVLDGVKQKQNGHTVQFDVVSNPEFLREGSAIFDTFNPDRIVLGSS
CCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHCCCCEEECCCCCEEEEECC
NSKAIALMKQLYDPLIQGQFSAPEHLKPIPVVETDLNSAEMIKYAANAFLATKISFINEV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ANVCDRVGADILQVAKGIGLDSRIGNKFLQAGLGWGGSCFPKDVAALVHTAEDYGYQAQL
HHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
LEAAVTVNNRQKLIVVEKLQQELKILKGKTIGLLGLTFKPDTDDMRDAPSLKLIAELNRL
HHHHHEECCCCEEEEHHHHHHHHHHHCCCEEEEEEEEECCCCCHHCCCCCHHHHHHHHHH
GARVKAYDPIVSQNGISQGLSGVLIENSPEMLADTCDALVLVTDWQEFLHLDYGQLGDRL
CCEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHCEEEEEECHHHHHHCCHHHHHHHH
QNRLIIDGRNFLDRDALEALGFRYVGIGH
HCCEEECCCCCCHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MKVCVIGTGYVGLVTGVCLAHMGHDVICIDNNEQKIKLMQAGRSPIYEPGLAELMQEEMA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
TGRLQFSTDLSFGVNHGEILFIAVGTPALPTGESDTRYVEAVAKGIGEHLPADSYKVIVN
CCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
KSTVPIGSGDWVRMIVLDGVKQKQNGHTVQFDVVSNPEFLREGSAIFDTFNPDRIVLGSS
CCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHCCCCEEECCCCCEEEEECC
NSKAIALMKQLYDPLIQGQFSAPEHLKPIPVVETDLNSAEMIKYAANAFLATKISFINEV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ANVCDRVGADILQVAKGIGLDSRIGNKFLQAGLGWGGSCFPKDVAALVHTAEDYGYQAQL
HHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
LEAAVTVNNRQKLIVVEKLQQELKILKGKTIGLLGLTFKPDTDDMRDAPSLKLIAELNRL
HHHHHEECCCCEEEEHHHHHHHHHHHCCCEEEEEEEEECCCCCHHCCCCCHHHHHHHHHH
GARVKAYDPIVSQNGISQGLSGVLIENSPEMLADTCDALVLVTDWQEFLHLDYGQLGDRL
CCEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHCEEEEEECHHHHHHCCHHHHHHHH
QNRLIIDGRNFLDRDALEALGFRYVGIGH
HCCEEECCCCCCHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10048024; 9384377; 10376820 [H]