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The map label for this gene is rfbB [H]

Identifier: 170078934

GI number: 170078934

Start: 2414941

End: 2416866

Strand: Direct

Name: rfbB [H]

Synonym: SYNPCC7002_A2339

Alternate gene names: 170078934

Gene position: 2414941-2416866 (Clockwise)

Preceding gene: 170078933

Following gene: 170078935

Centisome position: 80.28

GC content: 46.47

Gene sequence:

>1926_bases
ATGCGAATTCTAGTGACCGGCGGCGCAGGGTTCATCGGCTCCCATCTCATTGATCGCCTGATGACCGAAGGCCATGAAGT
CATTTGCCTCGATAACTTTTACACAGGCCGCAAGCATAACCTTTTGCAGTGGATTGGCAACCCCTACTTTGAAATGGTGC
GCCACGACATCACCGAACCGATCCGCCTCGAAGTGGATCAGGTTTACCACCTCGCTTGTCCTGCCTCACCGATCCATTAC
CAGTTCAACGCCATCAAAACCGTTAAAACCAACGTCATGGGCACCCTAAATATGTTGGGGTTAGCCAAACGGGTCAAAGC
GAGAATTCTGTTGGCGTCCACCTCTGAAGTCTATGGCGATCCGGAAGTTCATCCCCAGCCAGAAACCTACCATGGCAACG
TGAATCCCATCGGCATTCGCTCCTGTTACGACGACCAAACCGAAATTTTGACTGATTCCGGTTGGGTACTCTTCCCCGAA
TTACAACCCAACCAAAAAGTTGCCACCCTCAACGAACAAAACCAAGTGGAATATCATCTTCCCGATGAGTTCATTATTCA
ACCCTATCTTGGTCACTTGCTGAGATTTAATAACAGCAAATTCGATCTTTGTGTGACTCCAAACCACAAAATGTACGTCC
GCAGTAAGACAGGAAAACTCAAATTTCTTCAGGCTGATGAAAAGCGTCACTGGCATTCATGGAAAGTCATTACAGGCGCA
ATTTTTCAAGGTGAAGAGCTTAAAACTTTTACGTTTGGTCCCCCCCCTCTAAATGCCAAAGTTCGCTTTAATACTGTTTT
CATGGACGATTGGCTGGAATTCCTGGGCTATTATCTGTCCGAAGGCTGCACCCACGTTCGTCGTCGTGTACGGGTGGTAA
ATGGCAGTAATTACGACGTTGCTGATTATAATGTTCTGATTGCCCAAGAAAATCCTGAAGGACGCACCAAGATTGCTGCT
TGTTTAAATCGTTTGGGCTTTAAATATTTTGATTCTGATCATCATCAATTTAGGATTTGTAGCAAACAACTTGCTGAGAT
TCTATTGCCATTGGGTAAATCTGGTGAAAAATATATTCCCCGTGAATATCTGCGGTTATCACCACGGCAATCTCGCATTT
TGTTTGATGCGCTGATCATGGGTGACGGTTCTCAACGGGGTAATTGTTTTACCTATTACTCTAAATCAAAGCAACTAGCG
GATAATGTACAAGAATTAGCCTTACGGTGTGGCTTTGCTGCTTCTGTTGTGTCCCATGCGGTCGGACGGGATTTATATCG
GGTTAATATTCGCGTAGCTAAAGATGCGGCTCTGGTAGAACCAGAAAAAGTTTTTTACAAAGGGAATGTGTACTGCGTCA
ATGTCAAAAACCATGTGGTTTTGGTACGTCGTAATGGTCGGGTTGCTTTTTGTGGTAACTGTTACGACGAGGGGAAGCGG
ATGGCGGAAACCCTGGCTTTTGATTACCACCGCTCTAATAATGTTGATATCCGTGTCGCCCGAATTTTTAATACCTATGG
CCCCAATATGTTGCCGAATGATGGGCGGGTGGTGAGTAACTTTATCGTTCAAGCGCTCCAGGGGAAACCGTTGACGGTCT
ATGGGGATGGTTCCCAAACCCGCAGTTTTTGCTATGTGAGTGATTTGGTTGAAGGTTTGATTCGTTTGATGAACCAAAAC
TTTATCGGCCCCGTCAATTTAGGGAATCCCGATGAGTACACGATTTTGGAGTTGGCCCAAACGATTCAGAATATGGTCAA
TCCTGATGTTGAAGTCGCCTTTGAGCCGCTACCCCAGGATGATCCGCGTCAACGGCAACCGGACATTACCCGTGCTAAAA
CCTACTTGGATTGGCAGCCGACGGTGCCCCTCAAGGTGGGCTTAGAAAAAACGATCGCCTATTTCCGCGATCGCCTCGCA
GAATAA

Upstream 100 bases:

>100_bases
CGCCACGATCCTCGAAGGAGAACTAGATGGCTAGACAAAGTGTCTATCTCTCGCTACCGTTAGGAAAACCATCTGAACAG
TCATCGTTCCAGAACTAACC

Downstream 100 bases:

>100_bases
CTAACGGACAACAACACGAGAAATTCACTAGAAATTGCGATGAAAGTTTGTGTAATTGGAACGGGTTACGTGGGCCTGGT
CACAGGGGTTTGCCTGGCGC

Product: dTDP-glucose 4-6-dehydratase

Products: dTDP-4-dehydro-6-deoxy-D-glucose; H2O

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MRILVTGGAGFIGSHLIDRLMTEGHEVICLDNFYTGRKHNLLQWIGNPYFEMVRHDITEPIRLEVDQVYHLACPASPIHY
QFNAIKTVKTNVMGTLNMLGLAKRVKARILLASTSEVYGDPEVHPQPETYHGNVNPIGIRSCYDDQTEILTDSGWVLFPE
LQPNQKVATLNEQNQVEYHLPDEFIIQPYLGHLLRFNNSKFDLCVTPNHKMYVRSKTGKLKFLQADEKRHWHSWKVITGA
IFQGEELKTFTFGPPPLNAKVRFNTVFMDDWLEFLGYYLSEGCTHVRRRVRVVNGSNYDVADYNVLIAQENPEGRTKIAA
CLNRLGFKYFDSDHHQFRICSKQLAEILLPLGKSGEKYIPREYLRLSPRQSRILFDALIMGDGSQRGNCFTYYSKSKQLA
DNVQELALRCGFAASVVSHAVGRDLYRVNIRVAKDAALVEPEKVFYKGNVYCVNVKNHVVLVRRNGRVAFCGNCYDEGKR
MAETLAFDYHRSNNVDIRVARIFNTYGPNMLPNDGRVVSNFIVQALQGKPLTVYGDGSQTRSFCYVSDLVEGLIRLMNQN
FIGPVNLGNPDEYTILELAQTIQNMVNPDVEVAFEPLPQDDPRQRQPDITRAKTYLDWQPTVPLKVGLEKTIAYFRDRLA
E

Sequences:

>Translated_641_residues
MRILVTGGAGFIGSHLIDRLMTEGHEVICLDNFYTGRKHNLLQWIGNPYFEMVRHDITEPIRLEVDQVYHLACPASPIHY
QFNAIKTVKTNVMGTLNMLGLAKRVKARILLASTSEVYGDPEVHPQPETYHGNVNPIGIRSCYDDQTEILTDSGWVLFPE
LQPNQKVATLNEQNQVEYHLPDEFIIQPYLGHLLRFNNSKFDLCVTPNHKMYVRSKTGKLKFLQADEKRHWHSWKVITGA
IFQGEELKTFTFGPPPLNAKVRFNTVFMDDWLEFLGYYLSEGCTHVRRRVRVVNGSNYDVADYNVLIAQENPEGRTKIAA
CLNRLGFKYFDSDHHQFRICSKQLAEILLPLGKSGEKYIPREYLRLSPRQSRILFDALIMGDGSQRGNCFTYYSKSKQLA
DNVQELALRCGFAASVVSHAVGRDLYRVNIRVAKDAALVEPEKVFYKGNVYCVNVKNHVVLVRRNGRVAFCGNCYDEGKR
MAETLAFDYHRSNNVDIRVARIFNTYGPNMLPNDGRVVSNFIVQALQGKPLTVYGDGSQTRSFCYVSDLVEGLIRLMNQN
FIGPVNLGNPDEYTILELAQTIQNMVNPDVEVAFEPLPQDDPRQRQPDITRAKTYLDWQPTVPLKVGLEKTIAYFRDRLA
E
>Mature_641_residues
MRILVTGGAGFIGSHLIDRLMTEGHEVICLDNFYTGRKHNLLQWIGNPYFEMVRHDITEPIRLEVDQVYHLACPASPIHY
QFNAIKTVKTNVMGTLNMLGLAKRVKARILLASTSEVYGDPEVHPQPETYHGNVNPIGIRSCYDDQTEILTDSGWVLFPE
LQPNQKVATLNEQNQVEYHLPDEFIIQPYLGHLLRFNNSKFDLCVTPNHKMYVRSKTGKLKFLQADEKRHWHSWKVITGA
IFQGEELKTFTFGPPPLNAKVRFNTVFMDDWLEFLGYYLSEGCTHVRRRVRVVNGSNYDVADYNVLIAQENPEGRTKIAA
CLNRLGFKYFDSDHHQFRICSKQLAEILLPLGKSGEKYIPREYLRLSPRQSRILFDALIMGDGSQRGNCFTYYSKSKQLA
DNVQELALRCGFAASVVSHAVGRDLYRVNIRVAKDAALVEPEKVFYKGNVYCVNVKNHVVLVRRNGRVAFCGNCYDEGKR
MAETLAFDYHRSNNVDIRVARIFNTYGPNMLPNDGRVVSNFIVQALQGKPLTVYGDGSQTRSFCYVSDLVEGLIRLMNQN
FIGPVNLGNPDEYTILELAQTIQNMVNPDVEVAFEPLPQDDPRQRQPDITRAKTYLDWQPTVPLKVGLEKTIAYFRDRLA
E

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=144, Percent_Identity=69.4444444444444, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI7657641, Length=176, Percent_Identity=28.4090909090909, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1786974, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17539532, Length=144, Percent_Identity=71.5277777777778, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17568069, Length=172, Percent_Identity=31.3953488372093, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115532424, Length=181, Percent_Identity=33.1491712707182, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356223, Length=194, Percent_Identity=52.5773195876289, Blast_Score=228, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: 4.2.1.46

Molecular weight: Translated: 73246; Mature: 73246

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50817 INTEIN_N_TER ; PS50819 INTEIN_ENDONUCLEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGAGFIGSHLIDRLMTEGHEVICLDNFYTGRKHNLLQWIGNPYFEMVRHDITEP
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCC
IRLEVDQVYHLACPASPIHYQFNAIKTVKTNVMGTLNMLGLAKRVKARILLASTSEVYGD
EEEEHHHEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECHHHCCC
PEVHPQPETYHGNVNPIGIRSCYDDQTEILTDSGWVLFPELQPNQKVATLNEQNQVEYHL
CCCCCCCCCCCCCCCEEEEECCCCCCHHEEECCCCEEECCCCCCCEEEECCCCCCEEEEC
PDEFIIQPYLGHLLRFNNSKFDLCVTPNHKMYVRSKTGKLKFLQADEKRHWHSWKVITGA
CHHHHHHHHHHHHHEECCCCEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEEE
IFQGEELKTFTFGPPPLNAKVRFNTVFMDDWLEFLGYYLSEGCTHVRRRVRVVNGSNYDV
EECCCCEEEEECCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCE
ADYNVLIAQENPEGRTKIAACLNRLGFKYFDSDHHQFRICSKQLAEILLPLGKSGEKYIP
ECEEEEEEECCCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
REYLRLSPRQSRILFDALIMGDGSQRGNCFTYYSKSKQLADNVQELALRCGFAASVVSHA
HHHHHCCCCHHHEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHH
VGRDLYRVNIRVAKDAALVEPEKVFYKGNVYCVNVKNHVVLVRRNGRVAFCGNCYDEGKR
HCCCEEEEEEEEECCCCCCCCHHEEEECCEEEEEECCEEEEEEECCCEEEECCCHHHHHH
MAETLAFDYHRSNNVDIRVARIFNTYGPNMLPNDGRVVSNFIVQALQGKPLTVYGDGSQT
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
RSFCYVSDLVEGLIRLMNQNFIGPVNLGNPDEYTILELAQTIQNMVNPDVEVAFEPLPQD
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
DPRQRQPDITRAKTYLDWQPTVPLKVGLEKTIAYFRDRLAE
CCCCCCCCCHHHHEEECCCCCCCHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRILVTGGAGFIGSHLIDRLMTEGHEVICLDNFYTGRKHNLLQWIGNPYFEMVRHDITEP
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCC
IRLEVDQVYHLACPASPIHYQFNAIKTVKTNVMGTLNMLGLAKRVKARILLASTSEVYGD
EEEEHHHEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECHHHCCC
PEVHPQPETYHGNVNPIGIRSCYDDQTEILTDSGWVLFPELQPNQKVATLNEQNQVEYHL
CCCCCCCCCCCCCCCEEEEECCCCCCHHEEECCCCEEECCCCCCCEEEECCCCCCEEEEC
PDEFIIQPYLGHLLRFNNSKFDLCVTPNHKMYVRSKTGKLKFLQADEKRHWHSWKVITGA
CHHHHHHHHHHHHHEECCCCEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEEE
IFQGEELKTFTFGPPPLNAKVRFNTVFMDDWLEFLGYYLSEGCTHVRRRVRVVNGSNYDV
EECCCCEEEEECCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCE
ADYNVLIAQENPEGRTKIAACLNRLGFKYFDSDHHQFRICSKQLAEILLPLGKSGEKYIP
ECEEEEEEECCCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
REYLRLSPRQSRILFDALIMGDGSQRGNCFTYYSKSKQLADNVQELALRCGFAASVVSHA
HHHHHCCCCHHHEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHH
VGRDLYRVNIRVAKDAALVEPEKVFYKGNVYCVNVKNHVVLVRRNGRVAFCGNCYDEGKR
HCCCEEEEEEEEECCCCCCCCHHEEEECCEEEEEECCEEEEEEECCCEEEECCCHHHHHH
MAETLAFDYHRSNNVDIRVARIFNTYGPNMLPNDGRVVSNFIVQALQGKPLTVYGDGSQT
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
RSFCYVSDLVEGLIRLMNQNFIGPVNLGNPDEYTILELAQTIQNMVNPDVEVAFEPLPQD
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
DPRQRQPDITRAKTYLDWQPTVPLKVGLEKTIAYFRDRLAE
CCCCCCCCCHHHHEEECCCCCCCHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDPglucose

Specific reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]