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The map label for this gene is bvdR [H]

Identifier: 170078919

GI number: 170078919

Start: 2401641

End: 2402585

Strand: Reverse

Name: bvdR [H]

Synonym: SYNPCC7002_A2324

Alternate gene names: 170078919

Gene position: 2402585-2401641 (Counterclockwise)

Preceding gene: 170078922

Following gene: 170078918

Centisome position: 79.87

GC content: 54.29

Gene sequence:

>945_bases
GTGGGCATTGTCGGTACTGGTTACGCAGCTAAACGGCGGGCAGAGGCCTTTTTACGGGATGGACGGGCGGAACTAATGGC
CGTGGCAGGAAAATGGCAGCAAGCACGGGAGCAGTTCGCTAGTAACTATGATTTAGCGGCGATCGCCTCCTGGGAAAACC
TCATCCAGCGGGACGATCTCGATTTAATCGTCGTGTGTACGGTCAACCGACGTCATGGGGCAGTGGTGCGGGCGGCCCTC
GAAGCGGGGAAACACGTAGTAGTGGAATATCCTTTGTCCTTGGATCCCACCGAAGCTGCTGAATTGATTCAACTGGCCGA
GGCGAAAAAACGACTCCTCCATGTGGAGCATATTGAACTGTTGGGGGGACTGCACCAAACGATTCGGCAGACCTTACCGG
AACTGGGCGCGATCACCTATGGCCATTACATTACCCTTGCTCCCAAAGCGAAAACCCTACCCCACTGGACATACCATTAC
GAAGATTATGGTTTTCCCTTTGTGGCGGCCCTGTCGCGGGTGAACCGATTGCTGGATCTCTTTGGTACGGTCGAAACAGT
CACCGGGGCGGCCCAATTTCTCCCAGCAGAGTTGCCCGGCTACTACCAAAATTGCCTCTGTACGGCGCAACTAAAATTTC
AAAGTGGTGTGATTGCCCACCTCACCTACGGTAAAGGAGTCTTGATCCCCAAAGGCGATCGCCGTTTTAGTCTCTATGGC
GAAAAAGGCACTTTGGAATTTAACGGCAACCAAGGCACCCTAAGTCAAGGCGATCAACAGACAAACCTCGATGCGGGCAG
TCGGCGCGGCGTTTTCTTGCAGGATACGGTGGCGGTGCTGGATCATTTAACCGCAGGCAAGCCCCTCTATATTCAGCCAG
AACAAAGTTTATACGCTCTCCAGGTGGCCGCCCAAATCCAACGGGCTGCCCTGGGCCAAACCTAA

Upstream 100 bases:

>100_bases
CAGTTTCCATTAAACCCGTTTGGGGGCTCCGGGAAAATACCTGCCCCAGCAAGCACACAGCAGTTTGAGGAAAAAGCGTT
AGGCGATGGCAAAATTTCGA

Downstream 100 bases:

>100_bases
ATATTTCCCCGACTTCGCCGCTCTCGGCCCATGCCGCTCGATAAAATAGAGTCACGATTTACCTTGGGAAAATTATGGTT
GCGTTGTTCTCTGCCCAACA

Product: biliverdin reductase

Products: biliverdin; NADH; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGIVGTGYAAKRRAEAFLRDGRAELMAVAGKWQQAREQFASNYDLAAIASWENLIQRDDLDLIVVCTVNRRHGAVVRAAL
EAGKHVVVEYPLSLDPTEAAELIQLAEAKKRLLHVEHIELLGGLHQTIRQTLPELGAITYGHYITLAPKAKTLPHWTYHY
EDYGFPFVAALSRVNRLLDLFGTVETVTGAAQFLPAELPGYYQNCLCTAQLKFQSGVIAHLTYGKGVLIPKGDRRFSLYG
EKGTLEFNGNQGTLSQGDQQTNLDAGSRRGVFLQDTVAVLDHLTAGKPLYIQPEQSLYALQVAAQIQRAALGQT

Sequences:

>Translated_314_residues
MGIVGTGYAAKRRAEAFLRDGRAELMAVAGKWQQAREQFASNYDLAAIASWENLIQRDDLDLIVVCTVNRRHGAVVRAAL
EAGKHVVVEYPLSLDPTEAAELIQLAEAKKRLLHVEHIELLGGLHQTIRQTLPELGAITYGHYITLAPKAKTLPHWTYHY
EDYGFPFVAALSRVNRLLDLFGTVETVTGAAQFLPAELPGYYQNCLCTAQLKFQSGVIAHLTYGKGVLIPKGDRRFSLYG
EKGTLEFNGNQGTLSQGDQQTNLDAGSRRGVFLQDTVAVLDHLTAGKPLYIQPEQSLYALQVAAQIQRAALGQT
>Mature_313_residues
GIVGTGYAAKRRAEAFLRDGRAELMAVAGKWQQAREQFASNYDLAAIASWENLIQRDDLDLIVVCTVNRRHGAVVRAALE
AGKHVVVEYPLSLDPTEAAELIQLAEAKKRLLHVEHIELLGGLHQTIRQTLPELGAITYGHYITLAPKAKTLPHWTYHYE
DYGFPFVAALSRVNRLLDLFGTVETVTGAAQFLPAELPGYYQNCLCTAQLKFQSGVIAHLTYGKGVLIPKGDRRFSLYGE
KGTLEFNGNQGTLSQGDQQTNLDAGSRRGVFLQDTVAVLDHLTAGKPLYIQPEQSLYALQVAAQIQRAALGQT

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI33589854, Length=278, Percent_Identity=25.8992805755396, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081947, Length=255, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.3.1.24

Molecular weight: Translated: 34543; Mature: 34412

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIVGTGYAAKRRAEAFLRDGRAELMAVAGKWQQAREQFASNYDLAAIASWENLIQRDDL
CCEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCC
DLIVVCTVNRRHGAVVRAALEAGKHVVVEYPLSLDPTEAAELIQLAEAKKRLLHVEHIEL
CEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGGLHQTIRQTLPELGAITYGHYITLAPKAKTLPHWTYHYEDYGFPFVAALSRVNRLLDL
HHHHHHHHHHHHHHHCCEEECCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
FGTVETVTGAAQFLPAELPGYYQNCLCTAQLKFQSGVIAHLTYGKGVLIPKGDRRFSLYG
HHHHHHHHHHHHHCCCCCCCHHHHCEEEEEEEECCCEEEEEECCCEEEEECCCCEEEEEC
EKGTLEFNGNQGTLSQGDQQTNLDAGSRRGVFLQDTVAVLDHLTAGKPLYIQPEQSLYAL
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCEEECCCCHHHHH
QVAAQIQRAALGQT
HHHHHHHHHHCCCC
>Mature Secondary Structure 
GIVGTGYAAKRRAEAFLRDGRAELMAVAGKWQQAREQFASNYDLAAIASWENLIQRDDL
CEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCC
DLIVVCTVNRRHGAVVRAALEAGKHVVVEYPLSLDPTEAAELIQLAEAKKRLLHVEHIEL
CEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGGLHQTIRQTLPELGAITYGHYITLAPKAKTLPHWTYHYEDYGFPFVAALSRVNRLLDL
HHHHHHHHHHHHHHHCCEEECCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
FGTVETVTGAAQFLPAELPGYYQNCLCTAQLKFQSGVIAHLTYGKGVLIPKGDRRFSLYG
HHHHHHHHHHHHHCCCCCCCHHHHCEEEEEEEECCCEEEEEECCCEEEEECCCCEEEEEC
EKGTLEFNGNQGTLSQGDQQTNLDAGSRRGVFLQDTVAVLDHLTAGKPLYIQPEQSLYAL
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCEEECCCCHHHHH
QVAAQIQRAALGQT
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: bilirubin; NAD+; NADP+

Specific reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]