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The map label for this gene is ndhD

Identifier: 170078922

GI number: 170078922

Start: 2403828

End: 2405480

Strand: Reverse

Name: ndhD

Synonym: SYNPCC7002_A2327

Alternate gene names: 170078922

Gene position: 2405480-2403828 (Counterclockwise)

Preceding gene: 170078929

Following gene: 170078919

Centisome position: 79.97

GC content: 52.99

Gene sequence:

>1653_bases
ATGGCACCAGATTTCCCATGGTTGACGGCAATCATTGCCCTGCCAGCTCTTTCGACCCTATTGATCCCGTTGCTTCCTGA
TAAAGAAGGAAAAACTGTACGTTGGTACGCCCTAATCGTCGGTTTAGTCGATTTTGCGCTGATGTGCTTTGCTTTTTGGC
AACATTTTGACCCCCAGGCGACTGAGTTTCAATTGGCAGAGAGTTATCGTTGGCTGCCGTCCTTGGGAATTCAGTGGAGT
GTGGCGGTGGATGGAATTTCCGCGCCCCTTGTTCTCCTCGCTGGTTTTGTGACGACCCTCGCGATGTTTTCGGCCTGGCA
AGTTAATCAACGCCCCCGGCTTTTTTATGCCTTGATGCTGCTGCTCTATTCGGCGCAGATTGGAGTATTTGTCGCCAAGG
ATTTATTTTTATTCTTCCTAATGTGGGAGATCGAACTGATCCCTGTGTATCTCCTCGTTTGTATTTGGGGTGGGAAACGT
CGTCGTTATGCAGCGATGAAGTTTCTCCTCTACACAGCCGCAGCTTCTATTTTCATTCTCGTTGCGGCCCTGGCCCTGAG
CTTGAATCTTCCCGGTGGCCCGAACTTTGATCTAGGGGCGATCGCCCAACAGGATTATCCTCTGGGATTACAAATGTGGC
TCTATGCTGGGCTGTTAGTTTCCTTTGGCGTGAAGTTAGCGATTTTTCCTCTCCACACCTGGTTGCCCGATGCCCATGGC
GAAGCTTCCTCTCCCGTTTCCATGCTCCTGGCTGGCGTCCTGCTGAAAATGGGGGGCTACGGTCTCATGCGCTTCAATAT
GGAACTGCTACCCGACGCCCACGTGCGGTTTGCGCCCCTGTTGGTGATTTTGGGGGTGGTCAATATTGTTTATGGTGCGT
TTAGTTCCTTTGGCCAGACCAACATGAAACGCCGCCTCGCCTACTCCTCTGTGTCCCACATGGGATTTGTCCTGATTGGC
ATTGCCTCCTTTACGGATCTAGGGATCAATGGGGCGATGCTGCAAATGCTCTCCCACGGTCTGATTGCGTCGGTGCTCTT
TTTCCTCGCGGGAGTCACCTATGATCGCACGAAGACGATGGTCCTCGCGGAAGTGGGGGGCCTTGGTCAGGTTATGCCCA
AGGTTTTTGCGATGTTTACGGTGGGGGCTTTGGCTTCCCTGGCACTACCGGGCATGAGTGGTTTTGTGGGGGAACTCTCG
GTATTTGTGGGCCTCGCCAGCAGCGATACCTATAGCGCAACCTTCCGTACAATTACGGTTTTCCTTGCCGCCGTCGGCGT
AATCCTCACGCCCATTTATCTGCTCTCGATGCTCCGGGAAATGTTCTACACCCGCGAGATGGATCTCAGTTGCGATCTTG
GTCAACCGACCAATGTGGCGATCGCCGGGAATGCCCCCGTGTGTTTTGGGAATGACTGCGTATTACCGAGCAATGCCATT
TATGAAGATGCGCGGCCCCGGGAAATCTTTATCGCCACTTGTTTTACCGTTTTGATTATCGGCGTGGGACTCTATCCGAA
ACTGCTGATGCAAATGTACGATGCGAAAACCCAAACCCTCAATACCAGTGTGCGTCAGGCCCAGGCGATCGCCAAGCAAC
CCAGTGAGCCCATCGCCGCTTTACAGGCCCCAGAATTGACCATGCCTCACTAG

Upstream 100 bases:

>100_bases
GGATTTGGGCAGGGGGATTGCGACATTTTGCGGAGAAAGCACACCTCTTTGGTATGATGCTGGGATTCTAAACATTTCTA
CATATAGAAGCGAACAACTC

Downstream 100 bases:

>100_bases
CTTGTTTGATGTTTTCAATACAGTGACATCCCCAGTCCCCGATCCGTCGGGGATTTTTTTGTACTTGCACCCCGTGGCGC
AAAAAAATAGAAGCGCTTCC

Product: NAD(P)H-quinone oxidoreductase subunit 4

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I, chain 4 3; NDH-1, chain 4 3

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MAPDFPWLTAIIALPALSTLLIPLLPDKEGKTVRWYALIVGLVDFALMCFAFWQHFDPQATEFQLAESYRWLPSLGIQWS
VAVDGISAPLVLLAGFVTTLAMFSAWQVNQRPRLFYALMLLLYSAQIGVFVAKDLFLFFLMWEIELIPVYLLVCIWGGKR
RRYAAMKFLLYTAAASIFILVAALALSLNLPGGPNFDLGAIAQQDYPLGLQMWLYAGLLVSFGVKLAIFPLHTWLPDAHG
EASSPVSMLLAGVLLKMGGYGLMRFNMELLPDAHVRFAPLLVILGVVNIVYGAFSSFGQTNMKRRLAYSSVSHMGFVLIG
IASFTDLGINGAMLQMLSHGLIASVLFFLAGVTYDRTKTMVLAEVGGLGQVMPKVFAMFTVGALASLALPGMSGFVGELS
VFVGLASSDTYSATFRTITVFLAAVGVILTPIYLLSMLREMFYTREMDLSCDLGQPTNVAIAGNAPVCFGNDCVLPSNAI
YEDARPREIFIATCFTVLIIGVGLYPKLLMQMYDAKTQTLNTSVRQAQAIAKQPSEPIAALQAPELTMPH

Sequences:

>Translated_550_residues
MAPDFPWLTAIIALPALSTLLIPLLPDKEGKTVRWYALIVGLVDFALMCFAFWQHFDPQATEFQLAESYRWLPSLGIQWS
VAVDGISAPLVLLAGFVTTLAMFSAWQVNQRPRLFYALMLLLYSAQIGVFVAKDLFLFFLMWEIELIPVYLLVCIWGGKR
RRYAAMKFLLYTAAASIFILVAALALSLNLPGGPNFDLGAIAQQDYPLGLQMWLYAGLLVSFGVKLAIFPLHTWLPDAHG
EASSPVSMLLAGVLLKMGGYGLMRFNMELLPDAHVRFAPLLVILGVVNIVYGAFSSFGQTNMKRRLAYSSVSHMGFVLIG
IASFTDLGINGAMLQMLSHGLIASVLFFLAGVTYDRTKTMVLAEVGGLGQVMPKVFAMFTVGALASLALPGMSGFVGELS
VFVGLASSDTYSATFRTITVFLAAVGVILTPIYLLSMLREMFYTREMDLSCDLGQPTNVAIAGNAPVCFGNDCVLPSNAI
YEDARPREIFIATCFTVLIIGVGLYPKLLMQMYDAKTQTLNTSVRQAQAIAKQPSEPIAALQAPELTMPH
>Mature_549_residues
APDFPWLTAIIALPALSTLLIPLLPDKEGKTVRWYALIVGLVDFALMCFAFWQHFDPQATEFQLAESYRWLPSLGIQWSV
AVDGISAPLVLLAGFVTTLAMFSAWQVNQRPRLFYALMLLLYSAQIGVFVAKDLFLFFLMWEIELIPVYLLVCIWGGKRR
RYAAMKFLLYTAAASIFILVAALALSLNLPGGPNFDLGAIAQQDYPLGLQMWLYAGLLVSFGVKLAIFPLHTWLPDAHGE
ASSPVSMLLAGVLLKMGGYGLMRFNMELLPDAHVRFAPLLVILGVVNIVYGAFSSFGQTNMKRRLAYSSVSHMGFVLIGI
ASFTDLGINGAMLQMLSHGLIASVLFFLAGVTYDRTKTMVLAEVGGLGQVMPKVFAMFTVGALASLALPGMSGFVGELSV
FVGLASSDTYSATFRTITVFLAAVGVILTPIYLLSMLREMFYTREMDLSCDLGQPTNVAIAGNAPVCFGNDCVLPSNAIY
EDARPREIFIATCFTVLIIGVGLYPKLLMQMYDAKTQTLNTSVRQAQAIAKQPSEPIAALQAPELTMPH

Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran

COG id: COG1008

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 4 (chain M)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family

Homologues:

Organism=Homo sapiens, GI251831116, Length=332, Percent_Identity=34.6385542168675, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI251831117, Length=344, Percent_Identity=27.0348837209302, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788613, Length=457, Percent_Identity=36.5426695842451, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1788827, Length=293, Percent_Identity=27.3037542662116, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788831, Length=304, Percent_Identity=31.25, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI2367154, Length=224, Percent_Identity=31.25, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788614, Length=390, Percent_Identity=27.4358974358974, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788829, Length=303, Percent_Identity=28.0528052805281, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693160, Length=255, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU4C3_SYNP2 (B1XJL9)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001735560.1
- GeneID:   6057787
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A2327
- HOGENOM:   HBG643593
- OMA:   PINIYVE
- ProtClustDB:   PRK12561
- HAMAP:   MF_00491
- InterPro:   IPR022997
- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918
- PRINTS:   PR01437
- TIGRFAMs:   TIGR01972

Pfam domain/function: PF00361 Oxidored_q1

EC number: 1.6.5.3

Molecular weight: Translated: 60065; Mature: 59934

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d5633e4)-; HASH(0x1df6ee5c)-; HASH(0x1d308c20)-; HASH(0x1e2084d8)-; HASH(0x1d2efa3c)-; HASH(0x1d20ecbc)-; HASH(0x1d447ad0)-; HASH(0x1d3f7c9c)-; HASH(0x1e118270)-; HASH(0x1cef587c)-; HASH(0x1e3e95e8)-; HASH(0x1cd2a52c)-; HASH(0x1e40a024)-; HASH(0x1d4cd7bc)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCCCH
>Mature Secondary Structure 
APDFPWLTAIIALPALSTLLIPLLPDKEGKTVRWYALIVGLVDFALMCFAFWQHFDPQA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCC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HCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA