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The map label for this gene is yjcE [H]

Identifier: 170078892

GI number: 170078892

Start: 2375097

End: 2376689

Strand: Direct

Name: yjcE [H]

Synonym: SYNPCC7002_A2297

Alternate gene names: 170078892

Gene position: 2375097-2376689 (Clockwise)

Preceding gene: 170078889

Following gene: 170078893

Centisome position: 78.96

GC content: 49.28

Gene sequence:

>1593_bases
ATGCCTTTGGTCATGATTGTTTTAGCAGAACTTGCAGAAGCGGCGATTTCAACAAACTTGCAACAGTTTGTGTTGGTTTT
ATCGATCTCCCTAACCGTTGCAACCTTTTCACGGATTTTTAGTTGGTTGCGCCAAATCCCCTATACCCTCTTGTTGGTGA
TTGTGGGGCTGGGTTTGGCTTTTATTAATGTGCGTTTAGTGAATCTTTCGCCGGAGCTAATCCTTGAAATTTTCCTCCCA
CCGCTCTTGTTTGAAGCTGCTTGGAATATTCGTTGGCGCGAACTCCAGAAACAATGGTTACCGATTGCGTTGTTTGCCTT
GGCTGGGGTGGCGATCGCCATCTTTGGGATTGGCTTTGCCCTCAGTCAGTGGACGAGCTTGGCCCTGAGTTCTGCCTTGT
TAGCGGGGGCGGCCCTCTCGGCGACGGATCCGGTGTCGGTGGTGGCTTTATTCCGGGAGTTGGGGGCCAGTAAAAAACTC
ACGATGGTGATGGAAGGGGAAAGCCTCTTTAACGATGGAGTCGCAGTCGTAGCGTTTCTGTTGCTGGTGGGAATTCCCCT
CGGTACCCAGACTTTTTCGATGTCGGCGACGGTGGCAACTTTCCTGGTCTTTGTGGGCATTGGTGTCGGCTTCGGTTGTT
TGATTGGTTTTGGCATTTCTTTCTTAACCCAACGCTTCGATATTCCCCTCGTGGAGCAATCTTTAACCCTGGTATCGGCC
TATGGTACTTACCTTTTGACGGAGGAGTTGGGCGGTTCTGGGGTGATTGCGGTGGTGACTGTGGGGATGATTTTGGGGAA
TTTTGGTTCGAATATTGGCATGAATCCCCGTACCCGCCTAGTTGTTTCGGAATTCTGGGAATTTCTCGCGTTTTTTGTGA
ATTCGATTGTATTTCTGCTGATTGGTGATCAGGTCAATTTTGGCACCCTGGGGGAAAGCTTAGATGCAATTTTTGTGGCG
ATCGCCGCTGTGTTGGTGACGCGAGCCATTTCCGTCTATGGTTTGGGTTGGCTCTCCAATCAATTTAGTAATAATCCCCT
GAGCTTTTCTGAACAAACGGTGCTGTGGTGGGGCGGTCTGCGGGGATCAGTTTCCATTGCCGTGGCCTTGAGCGTGCCTG
TAGTGCTCGGCGATCGCCAAGAAATCATCAACATCATTTTTGGGGTGGTGCTATTCACCCTCCTGGTACAGGGCTTGACA
ACCCAGTGGGTTCTAGAAAAACTCGATTTAATTGGTGATCAACCGATTCGTCAGAAATATTCCGAGTATCTTGCCCGTCG
TGTCGCCCTCAAACGAGTGTTAAATTACCTCGACCAGTTAAACCTCGCTGCCGATGTGGACGAGGAATTCTACCGCTATG
AACGGGATCTCGTCGAAGGGGAATTAGAAACCATCGAAGAAAAAATCGAAAAACTCAAAAGTAGCCATCCCCAACTGCAA
GAACTGGATATGAAGCAGTTGCGCGATACCCTCCTGGATATCGAGGCGGACACCTATGCCGAATTTATCCGGGTGGGCCG
TTTAAATAAAGATCTTTCGCCCCTACTCCAGGAGACCTTGATCAAAGCCACCGAAAAAACAATTCAGAGTTAA

Upstream 100 bases:

>100_bases
GATGTTCTGGGCTAATGATCGCCTTCAAAAATTTAAAGACTCTTGATATTTCTGATGACAGAGGTCAATGCCTGTTAGCA
TCTGTAGAGATTATCTAGAC

Downstream 100 bases:

>100_bases
CCTCCCTTTGCAAAACAAATCATCACGATAAACGACAGGGCCAAGCCAGGGCTAAGGAGGGTCGCCAGGGTTAAAAGTTC
TTCGCCGGACATAAAAATAC

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MPLVMIVLAELAEAAISTNLQQFVLVLSISLTVATFSRIFSWLRQIPYTLLLVIVGLGLAFINVRLVNLSPELILEIFLP
PLLFEAAWNIRWRELQKQWLPIALFALAGVAIAIFGIGFALSQWTSLALSSALLAGAALSATDPVSVVALFRELGASKKL
TMVMEGESLFNDGVAVVAFLLLVGIPLGTQTFSMSATVATFLVFVGIGVGFGCLIGFGISFLTQRFDIPLVEQSLTLVSA
YGTYLLTEELGGSGVIAVVTVGMILGNFGSNIGMNPRTRLVVSEFWEFLAFFVNSIVFLLIGDQVNFGTLGESLDAIFVA
IAAVLVTRAISVYGLGWLSNQFSNNPLSFSEQTVLWWGGLRGSVSIAVALSVPVVLGDRQEIINIIFGVVLFTLLVQGLT
TQWVLEKLDLIGDQPIRQKYSEYLARRVALKRVLNYLDQLNLAADVDEEFYRYERDLVEGELETIEEKIEKLKSSHPQLQ
ELDMKQLRDTLLDIEADTYAEFIRVGRLNKDLSPLLQETLIKATEKTIQS

Sequences:

>Translated_530_residues
MPLVMIVLAELAEAAISTNLQQFVLVLSISLTVATFSRIFSWLRQIPYTLLLVIVGLGLAFINVRLVNLSPELILEIFLP
PLLFEAAWNIRWRELQKQWLPIALFALAGVAIAIFGIGFALSQWTSLALSSALLAGAALSATDPVSVVALFRELGASKKL
TMVMEGESLFNDGVAVVAFLLLVGIPLGTQTFSMSATVATFLVFVGIGVGFGCLIGFGISFLTQRFDIPLVEQSLTLVSA
YGTYLLTEELGGSGVIAVVTVGMILGNFGSNIGMNPRTRLVVSEFWEFLAFFVNSIVFLLIGDQVNFGTLGESLDAIFVA
IAAVLVTRAISVYGLGWLSNQFSNNPLSFSEQTVLWWGGLRGSVSIAVALSVPVVLGDRQEIINIIFGVVLFTLLVQGLT
TQWVLEKLDLIGDQPIRQKYSEYLARRVALKRVLNYLDQLNLAADVDEEFYRYERDLVEGELETIEEKIEKLKSSHPQLQ
ELDMKQLRDTLLDIEADTYAEFIRVGRLNKDLSPLLQETLIKATEKTIQS
>Mature_529_residues
PLVMIVLAELAEAAISTNLQQFVLVLSISLTVATFSRIFSWLRQIPYTLLLVIVGLGLAFINVRLVNLSPELILEIFLPP
LLFEAAWNIRWRELQKQWLPIALFALAGVAIAIFGIGFALSQWTSLALSSALLAGAALSATDPVSVVALFRELGASKKLT
MVMEGESLFNDGVAVVAFLLLVGIPLGTQTFSMSATVATFLVFVGIGVGFGCLIGFGISFLTQRFDIPLVEQSLTLVSAY
GTYLLTEELGGSGVIAVVTVGMILGNFGSNIGMNPRTRLVVSEFWEFLAFFVNSIVFLLIGDQVNFGTLGESLDAIFVAI
AAVLVTRAISVYGLGWLSNQFSNNPLSFSEQTVLWWGGLRGSVSIAVALSVPVVLGDRQEIINIIFGVVLFTLLVQGLTT
QWVLEKLDLIGDQPIRQKYSEYLARRVALKRVLNYLDQLNLAADVDEEFYRYERDLVEGELETIEEKIEKLKSSHPQLQE
LDMKQLRDTLLDIEADTYAEFIRVGRLNKDLSPLLQETLIKATEKTIQS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI15529998, Length=412, Percent_Identity=27.4271844660194, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI148727259, Length=392, Percent_Identity=28.5714285714286, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI14211919, Length=384, Percent_Identity=27.8645833333333, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI294997330, Length=370, Percent_Identity=28.1081081081081, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI110227626, Length=370, Percent_Identity=28.1081081081081, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI5454070, Length=368, Percent_Identity=28.2608695652174, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI41872703, Length=412, Percent_Identity=25.2427184466019, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27734935, Length=327, Percent_Identity=25.3822629969419, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI27777632, Length=480, Percent_Identity=23.5416666666667, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI194239733, Length=437, Percent_Identity=27.2311212814645, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4759144, Length=333, Percent_Identity=27.9279279279279, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1790501, Length=468, Percent_Identity=30.1282051282051, Blast_Score=135, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI71980847, Length=392, Percent_Identity=26.2755102040816, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71999817, Length=434, Percent_Identity=25.3456221198157, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71999819, Length=434, Percent_Identity=25.3456221198157, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71999821, Length=405, Percent_Identity=25.4320987654321, Blast_Score=118, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71992107, Length=355, Percent_Identity=26.1971830985915, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71992101, Length=355, Percent_Identity=26.1971830985915, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71987535, Length=430, Percent_Identity=26.7441860465116, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71987537, Length=430, Percent_Identity=26.7441860465116, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25150332, Length=398, Percent_Identity=24.6231155778894, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71990924, Length=382, Percent_Identity=26.1780104712042, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71990932, Length=382, Percent_Identity=26.1780104712042, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71993590, Length=350, Percent_Identity=26.5714285714286, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71993582, Length=350, Percent_Identity=26.5714285714286, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25147678, Length=409, Percent_Identity=25.1833740831296, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71987559, Length=445, Percent_Identity=23.8202247191011, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71987545, Length=445, Percent_Identity=23.8202247191011, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320663, Length=374, Percent_Identity=24.8663101604278, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221473212, Length=363, Percent_Identity=29.4765840220386, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI281364513, Length=367, Percent_Identity=29.4277929155313, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI221473222, Length=367, Percent_Identity=29.4277929155313, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI221473215, Length=367, Percent_Identity=29.4277929155313, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281360447, Length=382, Percent_Identity=27.4869109947644, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221510734, Length=382, Percent_Identity=27.2251308900524, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI221510738, Length=428, Percent_Identity=26.4018691588785, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221510732, Length=453, Percent_Identity=25.60706401766, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221510736, Length=453, Percent_Identity=25.60706401766, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24585580, Length=453, Percent_Identity=25.60706401766, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24585578, Length=453, Percent_Identity=25.60706401766, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI221510740, Length=453, Percent_Identity=25.60706401766, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 58241; Mature: 58110

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVMIVLAELAEAAISTNLQQFVLVLSISLTVATFSRIFSWLRQIPYTLLLVIVGLGLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FINVRLVNLSPELILEIFLPPLLFEAAWNIRWRELQKQWLPIALFALAGVAIAIFGIGFA
HHHHEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQWTSLALSSALLAGAALSATDPVSVVALFRELGASKKLTMVMEGESLFNDGVAVVAFL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHCCHHHHHHH
LLVGIPLGTQTFSMSATVATFLVFVGIGVGFGCLIGFGISFLTQRFDIPLVEQSLTLVSA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGTYLLTEELGGSGVIAVVTVGMILGNFGSNIGMNPRTRLVVSEFWEFLAFFVNSIVFLL
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGDQVNFGTLGESLDAIFVAIAAVLVTRAISVYGLGWLSNQFSNNPLSFSEQTVLWWGGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
RGSVSIAVALSVPVVLGDRQEIINIIFGVVLFTLLVQGLTTQWVLEKLDLIGDQPIRQKY
CCCEEEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHH
SEYLARRVALKRVLNYLDQLNLAADVDEEFYRYERDLVEGELETIEEKIEKLKSSHPQLQ
HHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELDMKQLRDTLLDIEADTYAEFIRVGRLNKDLSPLLQETLIKATEKTIQS
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLVMIVLAELAEAAISTNLQQFVLVLSISLTVATFSRIFSWLRQIPYTLLLVIVGLGLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FINVRLVNLSPELILEIFLPPLLFEAAWNIRWRELQKQWLPIALFALAGVAIAIFGIGFA
HHHHEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQWTSLALSSALLAGAALSATDPVSVVALFRELGASKKLTMVMEGESLFNDGVAVVAFL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHCCHHHHHHH
LLVGIPLGTQTFSMSATVATFLVFVGIGVGFGCLIGFGISFLTQRFDIPLVEQSLTLVSA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGTYLLTEELGGSGVIAVVTVGMILGNFGSNIGMNPRTRLVVSEFWEFLAFFVNSIVFLL
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGDQVNFGTLGESLDAIFVAIAAVLVTRAISVYGLGWLSNQFSNNPLSFSEQTVLWWGGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
RGSVSIAVALSVPVVLGDRQEIINIIFGVVLFTLLVQGLTTQWVLEKLDLIGDQPIRQKY
CCCEEEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHH
SEYLARRVALKRVLNYLDQLNLAADVDEEFYRYERDLVEGELETIEEKIEKLKSSHPQLQ
HHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ELDMKQLRDTLLDIEADTYAEFIRVGRLNKDLSPLLQETLIKATEKTIQS
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]