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The map label for this gene is uvrB [H]

Identifier: 170078851

GI number: 170078851

Start: 2336416

End: 2338437

Strand: Direct

Name: uvrB [H]

Synonym: SYNPCC7002_A2255

Alternate gene names: 170078851

Gene position: 2336416-2338437 (Clockwise)

Preceding gene: 170078849

Following gene: 170078860

Centisome position: 77.67

GC content: 46.59

Gene sequence:

>2022_bases
ATGTCTAACGGGAGTAATGTTTTGTTTCGTCTCCATGCCCCTTTTGAACCTACTGGTGATCAACCCCAGGCGATCGCCAA
ATTGGTGCAATCCTTAGCATCCCAAGCGAAATATCAGACCCTCTTGGGGGCGACGGGCACGGGCAAAACCTTTACGATGG
CGGCGGTGATCGCCCAGATGCAGAAACCCACCCTCGTTTTGGCACACAATAAAACCCTCGCGGCACAGCTTTGTAACGAG
TTGCGGCAATTTTTTCCCTACAACGCCGTGGAATATTTCATTAGTTATTACGACTATTATCAACCGGAAGCCTACATTCC
CGTCACCGATACTTATATTGAAAAAACCGCTTCGATCAACGACGAAATTGATATGTTGCGCCACTCCGCCACGCGATCAC
TGTTTGAACGCAAGGATGTGATTGTGGTGGCTTCCATTAGTTGTATCTACGGGTTAGGAATTCCGAGCGAATATTTAAAG
GCAGCTATTTCTCTCAAAGTAGGGGAAGAATTGGATCAGCGGGCGGTACTGCGGCAACTGGTGACCGTGCAATATAATCG
CAACGATACCGATTTAAGTCGCGGCAATTTTCGGGTGAAGGGCGACATTTTAGAAATTGTCCCTGCCTACGAAGATCGGG
TGATTCGCGTCGAATTTTTCGGCGATGAAATTGATGCGATTCGCCTCCTTGATCCCGTCACGGGTGAAATTTTACAAAGC
CTCGATCAGGTTAATATTTATCCCGCTCGCCACTTTGTTACGCCCCAAGAACAGTTGGCGATCGCCTGTGAACAAATCAA
AGCCGAATTAGATAGTCAACTCACAGTTTTAGAAGCAGAGAATAAACTCCTCGAAGCCCAGCGTTTAAAGCAGCGAACGA
GTTATGATCTCGAACTTTTACAGGAAGTTGGTTATTGTAATGGTGTCGAAAATTATTCCCGTTTCTTAGCCGGACGGGAA
GCCGGATCGCCCCCCGAATGTTTAATTGATTATTTCCCTGAAGATTGGCTTTTAGTGGTTGATGAATCCCATGTCACTGT
GCCGCAAATTCGGGGAATGTATAACGGTGATCAAGCCCGCAAAAAAGTCTTAATTGACCATGGCTTTCGGTTACCCAGTG
CCGCCGATAATCGTCCTTTAAAGTCTGAAGAATTTTGGCAAAAAGTCAATCAATGTGTGTTTGTTTCTGCGACCCCCGGT
AATTGGGAAATCGAGCAATCGGAAGCGCGGGTTATTGAGCAAGTCATTCGTCCCACAGGCGTTGTCGATCCAGAAATTGA
TGTGCGCCCCACCGACGGACAAGTGGATGATCTATTAGGGGAAATTCGTCAACGAGAAAAATTAAAAGAACGAGTTTTAA
TTACCACTTTAACGAAACGAATGGCGGAGGATTTAACGGATTATTTCAGTGACCAGGGAGTAGCCGTGCAATATCTCCAT
TCTGAGATTAAATCCATCGAACGAATTGAAATTTTGCAGGCGCTCCGCAAGGGAGAATTTGATGTTTTAATTGGGGTCAA
TTTACTCCGAGAAGGTTTAGATTTACCGGAGGTTTCCCTCGTCGCGATTATGGATGCCGATAAGGAAGGGTTCCTGCGGG
CGGAACGGTCTTTAATCCAAACCATTGGTCGGGCGGCGCGCCATGTGCGGGGTCAGGCGATCCTCTACGCCGATAATCTC
ACCGATAGTATGGCAAAGGCGATCGCCGAAACAGAACGCCGTCGCGTTATCCAAATCGCCTACAACAAAAAACACAACAT
CACCCCCCAACCGATCAAAAAGCGGGACGAAAATGCAATTTTATCTTTTCTCGATATTTCCCGCCGCTTAAATACCCAGC
AATTACAACAAGTTGTTGAACACATGGAGGAAGTCCCCCTCGAAAAAATTCCCGATGTGATTAAGCAGCTAGAAGAGCAA
ATGAAAGAAGCCGCCAAAAATCTCGAATTTGAACAGGCCGCTCTACTCCGCGATCAAATTAAAAAACTCCGCCATCAACT
TTTAGGGAGTCACGATAACTAG

Upstream 100 bases:

>100_bases
AATTATCCCAAATGATGGGACAAAGATTCCTTGCTGATCTTAGACACACTTTGTCATAAATTCGCAACATTGTTTCTAAA
GTATCTCATTAATTTAAGTT

Downstream 100 bases:

>100_bases
CAAACAAAAAAGCTGGAGAGAATTTCTCCAGCCCTGAGGATGTAATGTTATGCAATCAAAAAATGGTTTACTCGTCTTCT
TCTAGACCAAAGACGCGGGC

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MSNGSNVLFRLHAPFEPTGDQPQAIAKLVQSLASQAKYQTLLGATGTGKTFTMAAVIAQMQKPTLVLAHNKTLAAQLCNE
LRQFFPYNAVEYFISYYDYYQPEAYIPVTDTYIEKTASINDEIDMLRHSATRSLFERKDVIVVASISCIYGLGIPSEYLK
AAISLKVGEELDQRAVLRQLVTVQYNRNDTDLSRGNFRVKGDILEIVPAYEDRVIRVEFFGDEIDAIRLLDPVTGEILQS
LDQVNIYPARHFVTPQEQLAIACEQIKAELDSQLTVLEAENKLLEAQRLKQRTSYDLELLQEVGYCNGVENYSRFLAGRE
AGSPPECLIDYFPEDWLLVVDESHVTVPQIRGMYNGDQARKKVLIDHGFRLPSAADNRPLKSEEFWQKVNQCVFVSATPG
NWEIEQSEARVIEQVIRPTGVVDPEIDVRPTDGQVDDLLGEIRQREKLKERVLITTLTKRMAEDLTDYFSDQGVAVQYLH
SEIKSIERIEILQALRKGEFDVLIGVNLLREGLDLPEVSLVAIMDADKEGFLRAERSLIQTIGRAARHVRGQAILYADNL
TDSMAKAIAETERRRVIQIAYNKKHNITPQPIKKRDENAILSFLDISRRLNTQQLQQVVEHMEEVPLEKIPDVIKQLEEQ
MKEAAKNLEFEQAALLRDQIKKLRHQLLGSHDN

Sequences:

>Translated_673_residues
MSNGSNVLFRLHAPFEPTGDQPQAIAKLVQSLASQAKYQTLLGATGTGKTFTMAAVIAQMQKPTLVLAHNKTLAAQLCNE
LRQFFPYNAVEYFISYYDYYQPEAYIPVTDTYIEKTASINDEIDMLRHSATRSLFERKDVIVVASISCIYGLGIPSEYLK
AAISLKVGEELDQRAVLRQLVTVQYNRNDTDLSRGNFRVKGDILEIVPAYEDRVIRVEFFGDEIDAIRLLDPVTGEILQS
LDQVNIYPARHFVTPQEQLAIACEQIKAELDSQLTVLEAENKLLEAQRLKQRTSYDLELLQEVGYCNGVENYSRFLAGRE
AGSPPECLIDYFPEDWLLVVDESHVTVPQIRGMYNGDQARKKVLIDHGFRLPSAADNRPLKSEEFWQKVNQCVFVSATPG
NWEIEQSEARVIEQVIRPTGVVDPEIDVRPTDGQVDDLLGEIRQREKLKERVLITTLTKRMAEDLTDYFSDQGVAVQYLH
SEIKSIERIEILQALRKGEFDVLIGVNLLREGLDLPEVSLVAIMDADKEGFLRAERSLIQTIGRAARHVRGQAILYADNL
TDSMAKAIAETERRRVIQIAYNKKHNITPQPIKKRDENAILSFLDISRRLNTQQLQQVVEHMEEVPLEKIPDVIKQLEEQ
MKEAAKNLEFEQAALLRDQIKKLRHQLLGSHDN
>Mature_672_residues
SNGSNVLFRLHAPFEPTGDQPQAIAKLVQSLASQAKYQTLLGATGTGKTFTMAAVIAQMQKPTLVLAHNKTLAAQLCNEL
RQFFPYNAVEYFISYYDYYQPEAYIPVTDTYIEKTASINDEIDMLRHSATRSLFERKDVIVVASISCIYGLGIPSEYLKA
AISLKVGEELDQRAVLRQLVTVQYNRNDTDLSRGNFRVKGDILEIVPAYEDRVIRVEFFGDEIDAIRLLDPVTGEILQSL
DQVNIYPARHFVTPQEQLAIACEQIKAELDSQLTVLEAENKLLEAQRLKQRTSYDLELLQEVGYCNGVENYSRFLAGREA
GSPPECLIDYFPEDWLLVVDESHVTVPQIRGMYNGDQARKKVLIDHGFRLPSAADNRPLKSEEFWQKVNQCVFVSATPGN
WEIEQSEARVIEQVIRPTGVVDPEIDVRPTDGQVDDLLGEIRQREKLKERVLITTLTKRMAEDLTDYFSDQGVAVQYLHS
EIKSIERIEILQALRKGEFDVLIGVNLLREGLDLPEVSLVAIMDADKEGFLRAERSLIQTIGRAARHVRGQAILYADNLT
DSMAKAIAETERRRVIQIAYNKKHNITPQPIKKRDENAILSFLDISRRLNTQQLQQVVEHMEEVPLEKIPDVIKQLEEQM
KEAAKNLEFEQAALLRDQIKKLRHQLLGSHDN

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=669, Percent_Identity=57.3991031390135, Blast_Score=775, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=236, Percent_Identity=24.1525423728814, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 76494; Mature: 76363

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGSNVLFRLHAPFEPTGDQPQAIAKLVQSLASQAKYQTLLGATGTGKTFTMAAVIAQM
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QKPTLVLAHNKTLAAQLCNELRQFFPYNAVEYFISYYDYYQPEAYIPVTDTYIEKTASIN
CCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCC
DEIDMLRHSATRSLFERKDVIVVASISCIYGLGIPSEYLKAAISLKVGEELDQRAVLRQL
HHHHHHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VTVQYNRNDTDLSRGNFRVKGDILEIVPAYEDRVIRVEFFGDEIDAIRLLDPVTGEILQS
HHHEECCCCCCCCCCCEEEECHHHEECCCCCCCEEEEEEECCCCCHHHHCCCHHHHHHHH
LDQVNIYPARHFVTPQEQLAIACEQIKAELDSQLTVLEAENKLLEAQRLKQRTSYDLELL
HHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCHHHHHH
QEVGYCNGVENYSRFLAGREAGSPPECLIDYFPEDWLLVVDESHVTVPQIRGMYNGDQAR
HHCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCHHH
KKVLIDHGFRLPSAADNRPLKSEEFWQKVNQCVFVSATPGNWEIEQSEARVIEQVIRPTG
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCEECHHHHHHHHHHHCCCC
VVDPEIDVRPTDGQVDDLLGEIRQREKLKERVLITTLTKRMAEDLTDYFSDQGVAVQYLH
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SEIKSIERIEILQALRKGEFDVLIGVNLLREGLDLPEVSLVAIMDADKEGFLRAERSLIQ
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
TIGRAARHVRGQAILYADNLTDSMAKAIAETERRRVIQIAYNKKHNITPQPIKKRDENAI
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHCCCHHHH
LSFLDISRRLNTQQLQQVVEHMEEVPLEKIPDVIKQLEEQMKEAAKNLEFEQAALLRDQI
HHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KKLRHQLLGSHDN
HHHHHHHCCCCCC
>Mature Secondary Structure 
SNGSNVLFRLHAPFEPTGDQPQAIAKLVQSLASQAKYQTLLGATGTGKTFTMAAVIAQM
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QKPTLVLAHNKTLAAQLCNELRQFFPYNAVEYFISYYDYYQPEAYIPVTDTYIEKTASIN
CCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCC
DEIDMLRHSATRSLFERKDVIVVASISCIYGLGIPSEYLKAAISLKVGEELDQRAVLRQL
HHHHHHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VTVQYNRNDTDLSRGNFRVKGDILEIVPAYEDRVIRVEFFGDEIDAIRLLDPVTGEILQS
HHHEECCCCCCCCCCCEEEECHHHEECCCCCCCEEEEEEECCCCCHHHHCCCHHHHHHHH
LDQVNIYPARHFVTPQEQLAIACEQIKAELDSQLTVLEAENKLLEAQRLKQRTSYDLELL
HHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCHHHHHH
QEVGYCNGVENYSRFLAGREAGSPPECLIDYFPEDWLLVVDESHVTVPQIRGMYNGDQAR
HHCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCHHH
KKVLIDHGFRLPSAADNRPLKSEEFWQKVNQCVFVSATPGNWEIEQSEARVIEQVIRPTG
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCEECHHHHHHHHHHHCCCC
VVDPEIDVRPTDGQVDDLLGEIRQREKLKERVLITTLTKRMAEDLTDYFSDQGVAVQYLH
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SEIKSIERIEILQALRKGEFDVLIGVNLLREGLDLPEVSLVAIMDADKEGFLRAERSLIQ
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
TIGRAARHVRGQAILYADNLTDSMAKAIAETERRRVIQIAYNKKHNITPQPIKKRDENAI
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHCCCHHHH
LSFLDISRRLNTQQLQQVVEHMEEVPLEKIPDVIKQLEEQMKEAAKNLEFEQAALLRDQI
HHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KKLRHQLLGSHDN
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]