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The map label for this gene is ribE [H]

Identifier: 170078860

GI number: 170078860

Start: 2344320

End: 2345003

Strand: Direct

Name: ribE [H]

Synonym: SYNPCC7002_A2264

Alternate gene names: 170078860

Gene position: 2344320-2345003 (Clockwise)

Preceding gene: 170078851

Following gene: 170078866

Centisome position: 77.93

GC content: 53.65

Gene sequence:

>684_bases
GTGTTTACTGGATTGATTCAAGCCCTTGGTACCGTTAAAGCCCTTGGTGGCGATCGCTTTGCCATCGATATCCAGGGCGA
CGGCGCGGGTCAAGTGATGTCGGATCTAGCCCTCGGCGATAGTGTGGCCGTAGATGGCGTTTGTTTGACCGTCGAAACCA
TTGCCGAACAAGGATTTGTTGCTACGGCCTCCCCCGAAACCCTAAAACGCACCATCCTCGGTGATGCCGTTGCCCGCTCC
AATTGGGTGAATATTGAAACGTCCCTGCGGGTGGGCAGTAAGATCGGTGGTCATTTTGTGTCGGGCCATGTGGATACCAT
TGGCGCTTTAGAGAAGGTTGTCGAAACCGCCCGTGCCTGGGAACTGTGGTTTACGGCGATCGCCGATTACCAGACGACCT
GGGATATGAATATTTCCCCTTGTCTGGTGTCCAAGGGAAGCATTGCAGTGAATGGCATTAGTCTAACGGTGGCCGAATGC
GATCGCCTGGGGCAGTGGTTTAAGGTGGCGGTGATTCCCCATACCTACGCCGAAACCAATTTGGCCTATCTCAAGCCGGG
CAGTTGGGTGAACCTAGAGGGGGATATCCTCGCGAAATATGTCCAGCGATTTGTCAGTTACCAACGGGAACAAAAAGCCC
CTGACATTGGCCTCGACTTCCTCCAGGAACATGGCTATTTATAG

Upstream 100 bases:

>100_bases
TATCCTACAGCTTCGATATTCTGGGGGGATGTTGGGCCTGATTTTCGGTCAATTCCCGCTACAATCGAATGGCCCTTTTA
CTGCGATCGCATCACGCCCT

Downstream 100 bases:

>100_bases
GGACTGGATCGCCAGTTTTTTCTGCTGGGGCGTGACCTGGGTTTCTTCTCCTCTAACCGTTGGTAATTGTGCCTCGGCGT
CCTGAGTACGGGGCCGCATC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MFTGLIQALGTVKALGGDRFAIDIQGDGAGQVMSDLALGDSVAVDGVCLTVETIAEQGFVATASPETLKRTILGDAVARS
NWVNIETSLRVGSKIGGHFVSGHVDTIGALEKVVETARAWELWFTAIADYQTTWDMNISPCLVSKGSIAVNGISLTVAEC
DRLGQWFKVAVIPHTYAETNLAYLKPGSWVNLEGDILAKYVQRFVSYQREQKAPDIGLDFLQEHGYL

Sequences:

>Translated_227_residues
MFTGLIQALGTVKALGGDRFAIDIQGDGAGQVMSDLALGDSVAVDGVCLTVETIAEQGFVATASPETLKRTILGDAVARS
NWVNIETSLRVGSKIGGHFVSGHVDTIGALEKVVETARAWELWFTAIADYQTTWDMNISPCLVSKGSIAVNGISLTVAEC
DRLGQWFKVAVIPHTYAETNLAYLKPGSWVNLEGDILAKYVQRFVSYQREQKAPDIGLDFLQEHGYL
>Mature_227_residues
MFTGLIQALGTVKALGGDRFAIDIQGDGAGQVMSDLALGDSVAVDGVCLTVETIAEQGFVATASPETLKRTILGDAVARS
NWVNIETSLRVGSKIGGHFVSGHVDTIGALEKVVETARAWELWFTAIADYQTTWDMNISPCLVSKGSIAVNGISLTVAEC
DRLGQWFKVAVIPHTYAETNLAYLKPGSWVNLEGDILAKYVQRFVSYQREQKAPDIGLDFLQEHGYL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=198, Percent_Identity=33.8383838383838, Blast_Score=90, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319733, Length=213, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 24510; Mature: 24510

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLIQALGTVKALGGDRFAIDIQGDGAGQVMSDLALGDSVAVDGVCLTVETIAEQGFV
CHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEECCEEEEHHHHHHCCEE
ATASPETLKRTILGDAVARSNWVNIETSLRVGSKIGGHFVSGHVDTIGALEKVVETARAW
EECCHHHHHHHHHHHHHHCCCCEEEEEHEECCCCCCCEEECCCHHHHHHHHHHHHHHHHH
ELWFTAIADYQTTWDMNISPCLVSKGSIAVNGISLTVAECDRLGQWFKVAVIPHTYAETN
HHHHHHHHCCCEEECCCCCCEEEECCCEEEEEEEEEHHHHHCCCCEEEEEEECCCCCCCC
LAYLKPGSWVNLEGDILAKYVQRFVSYQREQKAPDIGLDFLQEHGYL
EEEECCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MFTGLIQALGTVKALGGDRFAIDIQGDGAGQVMSDLALGDSVAVDGVCLTVETIAEQGFV
CHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEECCEEEEHHHHHHCCEE
ATASPETLKRTILGDAVARSNWVNIETSLRVGSKIGGHFVSGHVDTIGALEKVVETARAW
EECCHHHHHHHHHHHHHHCCCCEEEEEHEECCCCCCCEEECCCHHHHHHHHHHHHHHHHH
ELWFTAIADYQTTWDMNISPCLVSKGSIAVNGISLTVAECDRLGQWFKVAVIPHTYAETN
HHHHHHHHCCCEEECCCCCCEEEECCCEEEEEEEEEHHHHHCCCCEEEEEEECCCCCCCC
LAYLKPGSWVNLEGDILAKYVQRFVSYQREQKAPDIGLDFLQEHGYL
EEEECCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]