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The map label for this gene is livH [H]

Identifier: 170078700

GI number: 170078700

Start: 2174749

End: 2175699

Strand: Reverse

Name: livH [H]

Synonym: SYNPCC7002_A2099

Alternate gene names: 170078700

Gene position: 2175699-2174749 (Counterclockwise)

Preceding gene: 170078704

Following gene: 170078699

Centisome position: 72.33

GC content: 51.31

Gene sequence:

>951_bases
ATGGATCTTACCCTGTTCCTCCAGCAACTTCTCAATGGTCTTTCCATTGGTAGTGTCTACGCGATTTTTGCCCTGGGTTA
TACCCTTGTTTTTTCGATTCTTGGCATTATCAATTTTGCCCACGGAGCGATTTTTACCCTAGGCGCTTACTTCACTTATC
TCTTTGCCGGAGGACAATTTGGCTTCAATGGCTTCTTGGCCCAGGTGAAATTACCCTTTGCCCTACCCTTTGGTTTAGCG
TTGTTAATTGGCTGCGGTTTCGCGGGCTGCGTTTCGATGTTAGTAGAATGGCTCGCGTTTCGCCCTTTACGCCTCCGGGG
CGCCGATCCCCTCCTGAGTTTGGTTTCTAGTCTGGGGGCTGCCGTGGTGATTGTGAATGGGATTCAGCTGTTGGTGGGCG
CAGAGATTTATACGTTTCCAGCGGATATTTACGGTGGTTTGCCGGAGTCGATTAACTTTGGCTCCCCAGAGCGACCGATT
CTGATCCGGACAGTACAGCTCATTATCTTGACGGTGTCCGCACTGGTTGTGACCCTGTTGACCTACGGCATGACCCGAAC
GAAATTTGGGAAAGCGATCCAAGCGGTGGCAGAGGATAGCACAACCGCCAGTCTCTTGGGAATTAATACGGAACAAGTGG
TGCGGGTGACGTTTTTTGTGAGCGGTGCCTTGGCAGGACTGGCGGGAACATTGGTGGGTTCTAGCGTGAGCATTGCGGGG
CCTTATTTTGGCATTAGCTATGGTTTGAAGGGATTAGGCGTAATTGTTCTAGGGGGTTTGGGAAATATTCCGGGAGCGGT
GCTGGGCGGTTTAATTATCGGCATGGCAGAAGCGTTCATTCCAGCGGATTTTTCAGGGTATCGGGAGGCGATCGCCTTTG
CGTTACTGTTTGGGATGTTGCTGCTCCGGCCCCAGGGGTTATTGGGCCAAAAAACGATTCAAAAGGTGTGA

Upstream 100 bases:

>100_bases
CTAGGGGTTACTCAGGATGATGGCGTTGAGAATGGGGCAGGACTTTCCCATTGGTGGTATTACTATTTAGAAACCACCGT
GCCGTTCTTCGCCTGACAAC

Downstream 100 bases:

>100_bases
GATGGCGGCATTTTTGAGTACCTACGGCTATTTGATCGTTTCTACGCTTCTGGGGGCACTGTTGGGGATCTCGGTTTACC
TACCACTGATGGCGGGTCAG

Product: permease protein of branched-chain amino acid ABC transporter

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MDLTLFLQQLLNGLSIGSVYAIFALGYTLVFSILGIINFAHGAIFTLGAYFTYLFAGGQFGFNGFLAQVKLPFALPFGLA
LLIGCGFAGCVSMLVEWLAFRPLRLRGADPLLSLVSSLGAAVVIVNGIQLLVGAEIYTFPADIYGGLPESINFGSPERPI
LIRTVQLIILTVSALVVTLLTYGMTRTKFGKAIQAVAEDSTTASLLGINTEQVVRVTFFVSGALAGLAGTLVGSSVSIAG
PYFGISYGLKGLGVIVLGGLGNIPGAVLGGLIIGMAEAFIPADFSGYREAIAFALLFGMLLLRPQGLLGQKTIQKV

Sequences:

>Translated_316_residues
MDLTLFLQQLLNGLSIGSVYAIFALGYTLVFSILGIINFAHGAIFTLGAYFTYLFAGGQFGFNGFLAQVKLPFALPFGLA
LLIGCGFAGCVSMLVEWLAFRPLRLRGADPLLSLVSSLGAAVVIVNGIQLLVGAEIYTFPADIYGGLPESINFGSPERPI
LIRTVQLIILTVSALVVTLLTYGMTRTKFGKAIQAVAEDSTTASLLGINTEQVVRVTFFVSGALAGLAGTLVGSSVSIAG
PYFGISYGLKGLGVIVLGGLGNIPGAVLGGLIIGMAEAFIPADFSGYREAIAFALLFGMLLLRPQGLLGQKTIQKV
>Mature_316_residues
MDLTLFLQQLLNGLSIGSVYAIFALGYTLVFSILGIINFAHGAIFTLGAYFTYLFAGGQFGFNGFLAQVKLPFALPFGLA
LLIGCGFAGCVSMLVEWLAFRPLRLRGADPLLSLVSSLGAAVVIVNGIQLLVGAEIYTFPADIYGGLPESINFGSPERPI
LIRTVQLIILTVSALVVTLLTYGMTRTKFGKAIQAVAEDSTTASLLGINTEQVVRVTFFVSGALAGLAGTLVGSSVSIAG
PYFGISYGLKGLGVIVLGGLGNIPGAVLGGLIIGMAEAFIPADFSGYREAIAFALLFGMLLLRPQGLLGQKTIQKV

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=320, Percent_Identity=36.25, Blast_Score=178, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 33014; Mature: 33014

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTLFLQQLLNGLSIGSVYAIFALGYTLVFSILGIINFAHGAIFTLGAYFTYLFAGGQF
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GFNGFLAQVKLPFALPFGLALLIGCGFAGCVSMLVEWLAFRPLRLRGADPLLSLVSSLGA
CCCHHEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHCH
AVVIVNGIQLLVGAEIYTFPADIYGGLPESINFGSPERPILIRTVQLIILTVSALVVTLL
HHHHHHHHHHHHCCHHEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TYGMTRTKFGKAIQAVAEDSTTASLLGINTEQVVRVTFFVSGALAGLAGTLVGSSVSIAG
HHCCHHHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
PYFGISYGLKGLGVIVLGGLGNIPGAVLGGLIIGMAEAFIPADFSGYREAIAFALLFGML
CHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LLRPQGLLGQKTIQKV
HHCCCCCCCHHHHHCC
>Mature Secondary Structure
MDLTLFLQQLLNGLSIGSVYAIFALGYTLVFSILGIINFAHGAIFTLGAYFTYLFAGGQF
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GFNGFLAQVKLPFALPFGLALLIGCGFAGCVSMLVEWLAFRPLRLRGADPLLSLVSSLGA
CCCHHEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHCH
AVVIVNGIQLLVGAEIYTFPADIYGGLPESINFGSPERPILIRTVQLIILTVSALVVTLL
HHHHHHHHHHHHCCHHEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TYGMTRTKFGKAIQAVAEDSTTASLLGINTEQVVRVTFFVSGALAGLAGTLVGSSVSIAG
HHCCHHHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
PYFGISYGLKGLGVIVLGGLGNIPGAVLGGLIIGMAEAFIPADFSGYREAIAFALLFGML
CHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LLRPQGLLGQKTIQKV
HHCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]