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The map label for this gene is aspA [H]

Identifier: 170078645

GI number: 170078645

Start: 2122077

End: 2123477

Strand: Direct

Name: aspA [H]

Synonym: SYNPCC7002_A2041

Alternate gene names: 170078645

Gene position: 2122077-2123477 (Clockwise)

Preceding gene: 170078639

Following gene: 170078646

Centisome position: 70.55

GC content: 51.39

Gene sequence:

>1401_bases
ATGAGCGCAGATTTTCGCATTGAAAAAGATTCCATGGGCGATCGCCAAATCCCTCACGACGCCTACTATGGCATCCAAAC
CCTGAGGGCGACGGAAAATTTTCCGATCAGCGGCATTAAACCCCTCCCTACCTATATCGATGCTTGCGTTCTGATCAAAA
AAGCGACGGCGATCGCCAATGCGGAACTCGGTTGTATTGAAGCCCAGATGTCCGAGGCAATTGTAAAAGCCTGTGATGAA
GTGTTGCAGGGGGCATTACGAGAGCAATTCGTCGTCGATGTGTACCAAGCGGGGGCTGGCACCTCCCACCACATGAATGT
CAACGAAGTCTTGGCGAACCGTGCCCTCGAACTTCTCGGCGGCGAAAAGGGCGATTACCAAACCGTTAGCCCCAACGATC
ATGTGAACTACGGGCAATCCACCAATGATGTGATTCCCACGGCAATTCGTATCGGTGGGTTATTAGCCCTCGAACATTGT
TTATATCCAGCTCTCTCTGGGGCGATCGCCACTTTGGATAATAAAGCAGAAGAATTTGCCCACATCGTCAAATCTGGCCG
CACCCACATGCAGGATGCCGTTCCCGTCCGGCTTGGGGAAGGATTCCGCGCTTGGGCAGAAATTTTAACCGCCCACATGG
GGCGCATCGAAACCGCCGCCAAAGATTTAACGGTTTTAGGTTTAGGCGGTAGTGCTTCCGGAACAGGTTTAAACACCCAT
CCCCAATATCGTTTCCGCGTGGCAGAAATTTTAAGTGAACTGATCGGGCAACCTTTGACCTCCGCCCCCCACCTAATGGC
AGCGATGCAAAGTATGTCGCCCTTCGTCAATGTTTCCGGTGCGTTGCGTAACCTTGCTCAGGATCTCGTGAAAATTTCCC
ATGATTTGCGTCTGATGGATTCTGGCCCCAACACTGGCTTTAAGGAAATTCAACTGCCCCCTGTGCAACCCGGTTCCTCG
ATTATGCCCGGTAAGTACAATCCCGTCATGGCGGAAATGACTTCTATGGTGTGCTTTCAGGTGATGGGCTACGATACGGC
GATCGCCTTTGCCGCCCAAGCAGGTCAATTGGAACTTAACGTGATGATGCCTCTGATTGCCTATGATTTAATCCACAGCA
TCGAAATTCTCGGCAACACCATCAAGGCCCTCAGCGACAAATGTATTGCAGGCATCACCGCCAACGAACAACGCTGTCAC
AATTATGCTGAAAGCAGTCTGTCCCTTGTGACAGCCCTCAATACCCATATCGGTTATCTCAACGCTGCCGATGTCGCCAA
GGAATCCTTGCAAACGGGCAAAACCCTCCGGCAAATTGTCCTCGAACGGGGCTTAATGGATGAGGCGACCCTGGCCCAAG
TTCTCGACCTCGAAAAAATGAGTCAATTACCCAGCAATTAA

Upstream 100 bases:

>100_bases
TCGGTTATCCTCCAGAGCATTGATTAGCTCCATTGTAAGATCTGAATTTCGTGCCATCCTTTTAAACTAGGGGGATACAA
ACTCGATTCAGTCAAAATAT

Downstream 100 bases:

>100_bases
TCGGGAATAAAAAAGGCGATCGCCTCAGGCAAAAGGGAAGGCGATCGCCACTCTAAACCAATGCACTTCAGTAAGATAGA
TTTAGGTTTTGTTGTGAAGA

Product: aspartate ammonia-lyase

Products: NA

Alternate protein names: Aspartase [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSADFRIEKDSMGDRQIPHDAYYGIQTLRATENFPISGIKPLPTYIDACVLIKKATAIANAELGCIEAQMSEAIVKACDE
VLQGALREQFVVDVYQAGAGTSHHMNVNEVLANRALELLGGEKGDYQTVSPNDHVNYGQSTNDVIPTAIRIGGLLALEHC
LYPALSGAIATLDNKAEEFAHIVKSGRTHMQDAVPVRLGEGFRAWAEILTAHMGRIETAAKDLTVLGLGGSASGTGLNTH
PQYRFRVAEILSELIGQPLTSAPHLMAAMQSMSPFVNVSGALRNLAQDLVKISHDLRLMDSGPNTGFKEIQLPPVQPGSS
IMPGKYNPVMAEMTSMVCFQVMGYDTAIAFAAQAGQLELNVMMPLIAYDLIHSIEILGNTIKALSDKCIAGITANEQRCH
NYAESSLSLVTALNTHIGYLNAADVAKESLQTGKTLRQIVLERGLMDEATLAQVLDLEKMSQLPSN

Sequences:

>Translated_466_residues
MSADFRIEKDSMGDRQIPHDAYYGIQTLRATENFPISGIKPLPTYIDACVLIKKATAIANAELGCIEAQMSEAIVKACDE
VLQGALREQFVVDVYQAGAGTSHHMNVNEVLANRALELLGGEKGDYQTVSPNDHVNYGQSTNDVIPTAIRIGGLLALEHC
LYPALSGAIATLDNKAEEFAHIVKSGRTHMQDAVPVRLGEGFRAWAEILTAHMGRIETAAKDLTVLGLGGSASGTGLNTH
PQYRFRVAEILSELIGQPLTSAPHLMAAMQSMSPFVNVSGALRNLAQDLVKISHDLRLMDSGPNTGFKEIQLPPVQPGSS
IMPGKYNPVMAEMTSMVCFQVMGYDTAIAFAAQAGQLELNVMMPLIAYDLIHSIEILGNTIKALSDKCIAGITANEQRCH
NYAESSLSLVTALNTHIGYLNAADVAKESLQTGKTLRQIVLERGLMDEATLAQVLDLEKMSQLPSN
>Mature_465_residues
SADFRIEKDSMGDRQIPHDAYYGIQTLRATENFPISGIKPLPTYIDACVLIKKATAIANAELGCIEAQMSEAIVKACDEV
LQGALREQFVVDVYQAGAGTSHHMNVNEVLANRALELLGGEKGDYQTVSPNDHVNYGQSTNDVIPTAIRIGGLLALEHCL
YPALSGAIATLDNKAEEFAHIVKSGRTHMQDAVPVRLGEGFRAWAEILTAHMGRIETAAKDLTVLGLGGSASGTGLNTHP
QYRFRVAEILSELIGQPLTSAPHLMAAMQSMSPFVNVSGALRNLAQDLVKISHDLRLMDSGPNTGFKEIQLPPVQPGSSI
MPGKYNPVMAEMTSMVCFQVMGYDTAIAFAAQAGQLELNVMMPLIAYDLIHSIEILGNTIKALSDKCIAGITANEQRCHN
YAESSLSLVTALNTHIGYLNAADVAKESLQTGKTLRQIVLERGLMDEATLAQVLDLEKMSQLPSN

Specific function: Unknown

COG id: COG1027

COG function: function code E; Aspartate ammonia-lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily [H]

Homologues:

Organism=Homo sapiens, GI19743875, Length=444, Percent_Identity=43.018018018018, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI87082375, Length=463, Percent_Identity=47.5161987041037, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1787896, Length=455, Percent_Identity=43.7362637362637, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17553882, Length=461, Percent_Identity=43.6008676789588, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI32565146, Length=322, Percent_Identity=42.5465838509317, Blast_Score=254, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6324993, Length=463, Percent_Identity=42.3326133909287, Blast_Score=373, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24640179, Length=463, Percent_Identity=41.9006479481641, Blast_Score=359, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24640177, Length=463, Percent_Identity=41.9006479481641, Blast_Score=359, Evalue=2e-99,
Organism=Drosophila melanogaster, GI78710009, Length=449, Percent_Identity=42.0935412026726, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI24583245, Length=450, Percent_Identity=39.1111111111111, Blast_Score=341, Evalue=7e-94,
Organism=Drosophila melanogaster, GI24662684, Length=459, Percent_Identity=41.1764705882353, Blast_Score=340, Evalue=9e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004708
- InterPro:   IPR003031
- InterPro:   IPR018951
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761 [H]

Pfam domain/function: PF10415 FumaraseC_C; PF00206 Lyase_1 [H]

EC number: =4.3.1.1 [H]

Molecular weight: Translated: 50229; Mature: 50098

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADFRIEKDSMGDRQIPHDAYYGIQTLRATENFPISGIKPLPTYIDACVLIKKATAIAN
CCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AELGCIEAQMSEAIVKACDEVLQGALREQFVVDVYQAGAGTSHHMNVNEVLANRALELLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GEKGDYQTVSPNDHVNYGQSTNDVIPTAIRIGGLLALEHCLYPALSGAIATLDNKAEEFA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIVKSGRTHMQDAVPVRLGEGFRAWAEILTAHMGRIETAAKDLTVLGLGGSASGTGLNTH
HHHHCCCHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCC
PQYRFRVAEILSELIGQPLTSAPHLMAAMQSMSPFVNVSGALRNLAQDLVKISHDLRLMD
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEE
SGPNTGFKEIQLPPVQPGSSIMPGKYNPVMAEMTSMVCFQVMGYDTAIAFAAQAGQLELN
CCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHH
VMMPLIAYDLIHSIEILGNTIKALSDKCIAGITANEQRCHNYAESSLSLVTALNTHIGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NAADVAKESLQTGKTLRQIVLERGLMDEATLAQVLDLEKMSQLPSN
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SADFRIEKDSMGDRQIPHDAYYGIQTLRATENFPISGIKPLPTYIDACVLIKKATAIAN
CCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
AELGCIEAQMSEAIVKACDEVLQGALREQFVVDVYQAGAGTSHHMNVNEVLANRALELLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GEKGDYQTVSPNDHVNYGQSTNDVIPTAIRIGGLLALEHCLYPALSGAIATLDNKAEEFA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIVKSGRTHMQDAVPVRLGEGFRAWAEILTAHMGRIETAAKDLTVLGLGGSASGTGLNTH
HHHHCCCHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCC
PQYRFRVAEILSELIGQPLTSAPHLMAAMQSMSPFVNVSGALRNLAQDLVKISHDLRLMD
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEE
SGPNTGFKEIQLPPVQPGSSIMPGKYNPVMAEMTSMVCFQVMGYDTAIAFAAQAGQLELN
CCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEHH
VMMPLIAYDLIHSIEILGNTIKALSDKCIAGITANEQRCHNYAESSLSLVTALNTHIGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NAADVAKESLQTGKTLRQIVLERGLMDEATLAQVLDLEKMSQLPSN
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]