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The map label for this gene is menA [H]

Identifier: 170078588

GI number: 170078588

Start: 2067590

End: 2068540

Strand: Reverse

Name: menA [H]

Synonym: SYNPCC7002_A1984

Alternate gene names: 170078588

Gene position: 2068540-2067590 (Counterclockwise)

Preceding gene: 170078589

Following gene: 170078584

Centisome position: 68.77

GC content: 52.05

Gene sequence:

>951_bases
ATGCTCACGGAAAACCCACCCACCTCTAGTCCGAAAGCTACCCGTCGTCTTTGGCTTGCGGCGATTAAACCCCCCATTTA
TACGGTGGCAGTGACCCCTGTGATCGTGACAACGGCAGCGGCCTATGGGGAATTTGGGGTGTTTAACCCGGTGCGGTTTG
GGCTTTTCCTAGGGGCGGCAATTTGCTTAATTGCTTGGATGAATCTCAGTAATGATGTGTTCGACGCGGACACGGGCATT
GATGTCAATAAAGCGACTTCGGTGGTCAATCTCACGGGCGATCGCCCATTGGTTTTTGGCATTGCCCTCGGTTTTTTGGG
TCTGGGAATCACCGGAATTGCCTTAATCAGCTACCTCCAGCAGGATTGGATGGTGTTTAATTTGTTGCTCCTGGCAACGG
CGATCGCCTACACCTACCAGGGGCCACCGTTTCGCTTGGGTTATCTCGGTATTGGCGAGTTCGTCTGTTTTCTCGCCTAT
TGGATTACGGGTCAGGGAGTCTTTTATAGCCAAGCCCAAACCCTCACGCTCAATGCGGTCTGGGCCTCAGCTTGGGTTGC
TTTGACCACCAGTATTATTTTGTTTTGCTCCCATTTTCACCAGGCCGAAGATGACCTAGCCGCCGGGAAAAAATCACCCA
TTGTCCGCCTCGGCACCTACCAAGGGGCGCAGGTATTGACCTACAGCCTGGGAGCCGTTTTAGTTTTGACCTGCCTATTA
GTGGCTGTCGGCACCTGGTCACCCTGGATGCTCCTCACGTTTGCCAGTGCCCCCTTTGCCCTGAGTCTGATCAACCATGT
CCGCCTGAACCATGACCAACCTGACAAGGTGAGTAACTGCAAATTTTTTGCGGTCAAGTTTCACTTTGCCAGCGGTCTAT
TGTTGGCGATCGCCTATGTTTTGTCCTATTACAACCTAGAATTTCTCAGTGTTACGGGCTTGGGTTATTAG

Upstream 100 bases:

>100_bases
ATTTTCACAGCTAAAGTGTATTGGGGCATTGCTTCGCTCCTCCCCCCTTGCGGAAAGGTTAAGGTACACTTTTCTGAAGA
ATTGGCTCATTTAATCAATA

Downstream 100 bases:

>100_bases
CGATAGTTCGTAAACTGAATCGGCATCGGGAAATCCAAATCTCGCACCGCCTGCATTACTGCCTGGAGGTCATCTTTTGA
CTTGCTCGAAATGCGGACAG

Product: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLTENPPTSSPKATRRLWLAAIKPPIYTVAVTPVIVTTAAAYGEFGVFNPVRFGLFLGAAICLIAWMNLSNDVFDADTGI
DVNKATSVVNLTGDRPLVFGIALGFLGLGITGIALISYLQQDWMVFNLLLLATAIAYTYQGPPFRLGYLGIGEFVCFLAY
WITGQGVFYSQAQTLTLNAVWASAWVALTTSIILFCSHFHQAEDDLAAGKKSPIVRLGTYQGAQVLTYSLGAVLVLTCLL
VAVGTWSPWMLLTFASAPFALSLINHVRLNHDQPDKVSNCKFFAVKFHFASGLLLAIAYVLSYYNLEFLSVTGLGY

Sequences:

>Translated_316_residues
MLTENPPTSSPKATRRLWLAAIKPPIYTVAVTPVIVTTAAAYGEFGVFNPVRFGLFLGAAICLIAWMNLSNDVFDADTGI
DVNKATSVVNLTGDRPLVFGIALGFLGLGITGIALISYLQQDWMVFNLLLLATAIAYTYQGPPFRLGYLGIGEFVCFLAY
WITGQGVFYSQAQTLTLNAVWASAWVALTTSIILFCSHFHQAEDDLAAGKKSPIVRLGTYQGAQVLTYSLGAVLVLTCLL
VAVGTWSPWMLLTFASAPFALSLINHVRLNHDQPDKVSNCKFFAVKFHFASGLLLAIAYVLSYYNLEFLSVTGLGY
>Mature_316_residues
MLTENPPTSSPKATRRLWLAAIKPPIYTVAVTPVIVTTAAAYGEFGVFNPVRFGLFLGAAICLIAWMNLSNDVFDADTGI
DVNKATSVVNLTGDRPLVFGIALGFLGLGITGIALISYLQQDWMVFNLLLLATAIAYTYQGPPFRLGYLGIGEFVCFLAY
WITGQGVFYSQAQTLTLNAVWASAWVALTTSIILFCSHFHQAEDDLAAGKKSPIVRLGTYQGAQVLTYSLGAVLVLTCLL
VAVGTWSPWMLLTFASAPFALSLINHVRLNHDQPDKVSNCKFFAVKFHFASGLLLAIAYVLSYYNLEFLSVTGLGY

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

Organism=Escherichia coli, GI1790365, Length=314, Percent_Identity=25.796178343949, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011937
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 34319; Mature: 34319

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTENPPTSSPKATRRLWLAAIKPPIYTVAVTPVIVTTAAAYGEFGVFNPVRFGLFLGAA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ICLIAWMNLSNDVFDADTGIDVNKATSVVNLTGDRPLVFGIALGFLGLGITGIALISYLQ
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QDWMVFNLLLLATAIAYTYQGPPFRLGYLGIGEFVCFLAYWITGQGVFYSQAQTLTLNAV
HHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEHH
WASAWVALTTSIILFCSHFHQAEDDLAAGKKSPIVRLGTYQGAQVLTYSLGAVLVLTCLL
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VAVGTWSPWMLLTFASAPFALSLINHVRLNHDQPDKVSNCKFFAVKFHFASGLLLAIAYV
HHHCCCCHHHHEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHH
LSYYNLEFLSVTGLGY
HHHHCEEEEEEECCCC
>Mature Secondary Structure
MLTENPPTSSPKATRRLWLAAIKPPIYTVAVTPVIVTTAAAYGEFGVFNPVRFGLFLGAA
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ICLIAWMNLSNDVFDADTGIDVNKATSVVNLTGDRPLVFGIALGFLGLGITGIALISYLQ
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QDWMVFNLLLLATAIAYTYQGPPFRLGYLGIGEFVCFLAYWITGQGVFYSQAQTLTLNAV
HHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEHH
WASAWVALTTSIILFCSHFHQAEDDLAAGKKSPIVRLGTYQGAQVLTYSLGAVLVLTCLL
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VAVGTWSPWMLLTFASAPFALSLINHVRLNHDQPDKVSNCKFFAVKFHFASGLLLAIAYV
HHHCCCCHHHHEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHH
LSYYNLEFLSVTGLGY
HHHHCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]