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The map label for this gene is fadD21 [H]

Identifier: 170078584

GI number: 170078584

Start: 2062148

End: 2065441

Strand: Reverse

Name: fadD21 [H]

Synonym: SYNPCC7002_A1979

Alternate gene names: 170078584

Gene position: 2065441-2062148 (Counterclockwise)

Preceding gene: 170078588

Following gene: 170078583

Centisome position: 68.66

GC content: 51.43

Gene sequence:

>3294_bases
TTGATTTACTGCTTTATGACGTTTCTCCAGCATTCTATCCAGGCACAAGCATCGTTGCTCGATATCCTCAATGAGCGGGC
ACGCAGCCAACCCAATGCCCAAGCCTATGTTTTTTTAGAAAATGGAGAAACTGAATCTGGTCACCTCACTTACCAAGAAT
TAGCGACCCAGGCGAAGGCGATCGCCTCCCATCTGACCCCCTGGCGTGGGGAACGGGCATTGTTACTGTATCCGTCTGGA
TTGGCGTTTATCACAGCATTTTTGGGGTGTCTTTATGCCGGGGTGATTGCGGTGCCTGTCTATCCGCCGAAGCGCAACCA
AAAGTTATCGCGCCTGTTGGCGATCGCCGATAATGCCCAGGCCGAACTTGCCCTAACCACCGAGGCTTTGTTAGGAGATA
TTCAACAAAGATTTGCCCAAGCAGAGCAGTTTCAGGATTTAACCTTTTTGGCGACGGATACTTTAAAACAAGCTCCCCAA
GGCTTCAAGCCCCAGACAATTCAGGGGGATGATCTAGCATTTCTGCAATACACTTCTGGCTCTACGGGGACACCCAAGGG
CGTGATGGTTTCCCACCGGAATATCCTCCACAACCAGCGACTGATTCAAACCGCCTTTGGCCATAGTGAAAAGAGTATCG
GGGTCGGTTGGCTGCCCCTTTTCCATGATATGGGTCTCATTGGCCATGTACTCCAGCCGCTTTACGTGGGCTTTCCCAGT
ATTTTGATGCCTCCGGTGGCGTTTTTGACAAATCCCCGCCGCTGGCTCCAGGCGATCGCCAAATATCGGGCTACGACCAG
CGGTGGGCCAAATTTTGCCTATGATCTGTGTGTTGATCGCCTGACGGACAGTGATCTAGCCGATCTAGATTTAAGCAGTT
GGAATCTTGCCTACAGTGGTGCGGAACCAGTGCGGGCGGCGACCCTCGAAAAATTCAATCAAAAATTTGCCCCCTGTGGT
TTCCGGCCAGAGGCCTTTTATCCCTGCTATGGCATGGCGGAGGCGACCCTATTCATTACGGGGGGTGATAAGCAACAAGC
CCCGATCACCACCAGTTCGTCCGAAGAGTCAGACAATTTATTTGTTAGTTGTGGCCAACCCTACCATGACACCCAGGTGG
CGATCGTCGATCCGGAGTCTTTTGCCCCTTGTCCTGAAGGGACGACTGGGGAAGTGTGGGTGCGGGGGGACAGTGTCGCC
CGGGGTTATTGGAATGCCCCCATTGCCACCCAGGAAACCTTTACGGCAACTCTCAATCACCATCAAAAATCTTTCCTGCG
CACTGGTGATCTTGGTTTTATCGCCGCAGGAGAACTGTTCATTACCGGTCGCCTTAAGGATTTAATTATCGTCCGAGGAA
AAAATCACTATCCCCACGACATCGAGCTTACGGCTCAACAGTCTCACCCAGCTCTCCGGGAAAATTGCGGGGCGGCCTTC
ACGGTAGAAATTGACGGTACAGAACGCCTAATGCTGGTGCAAGAGGTAAAACGAACCTTTCTCCGAAATCTGGATGTCGA
GGCGATCGCCCAAAAAATCCGTCAAACGATCGCGGCAAACCATGAACTACAAACCTATGGCATCATCCTGATTAAAACCG
GTAGTATCCCGAAAACGTCCAGCGGTAAAATCCAACGACACCGTTGCCGTCAGGCGTTTCTGGCCGATGAGTTGATGGTT
GTGGGCCGCAGCGTCCTGGGTGAAGTAGATCATGCTTCCGCCCAAAGTTTTAATCCTCCCCAGAAACAACAACCCTCCCA
GCCGACCACTGACTTAATTAAACCCCTCCGCGAACAATTGGCCCAAGCCCTCTCGTTGCCCCTTGATACCATCCAAGACG
ATCAGCCCATCGCCGCTTTGGGCCTAGATTCCGTGCAAGTTGTTGAAATCAAGCATTACATCGAGCAAAAATTCGACTTA
ATAGTGCCCCTTGAAAAATTTTTTGAGGATCTTACCGTTGCCCAACTCGCCCAAGATATCCTGACTCTAGCTAATCTCCC
CCAAGAATCCCAACATCACCAAAACGGACATCTCCCCCAAGCGACTCAGCTAGAAGCAGAGGGCATCGATCTCGACCAAC
GGTTGCGCCTCGCTTATAAACCAAGCCGCAATGTCCTCGATAAAGCCAGGGAGTTTAACCTGCCGGATCAATTGCGAGCT
AATGATCTACTGCCCTATTTCCGTGCCCTTGAACGCAATGAAGGGGCCACCTGTATTTTTGAAGGGCGACAACTAATTAT
GTTGGGCTCCAATAATTATCTGGGGCTGACTGCCGATGTCCGAGTACGAGAAGCCACTGCCAAGGCCGCTCTAGAAGAAG
GGCCGAGTTTAACGGGATCACGATTGCTCAATGGTTCGACCCGCCAACACCGAGAATTTGAGCGAAAACTTGCCGCCTTC
GTCGGTCATGAGGATGCTCTAGTCTTTACCACGGGATATCAAGCGAATTTAGGCTTTATTTCCGCCTTAATGAACGAAAA
TACAACGATGATCCTCGACAGTGAGGCCCATGCTTGCATTTACGATGGGGCGTTTATGAGTCGCTGCCGGGTAGTTCAAT
ACCAGCACAATGACCTGCAAGATTTAGAACAAAAATTGATCCAGGTGACGCCAGAGTCCGCAACAATGGTCACGATTGAT
GGTCTGTATTCAATGACGGGGGATATTGCGCCCCTACCAGAAATTCGGCAATTATGCGATCGCCATGGGGCTACCCTCGC
AGTAGATGATGCCCATGCTCTGGGTGTTTTGGGAAAAACGGGCCGGGGGACGGAGGAGCATTTCGGGATGATCGACAGCA
GTGATATTCTTTGTGGCACTTTTTCCAAGAGTTTGGCTTCCATTGGCGGTTGGGTCGCCGCCGAAGCAAAGGTGATTGAT
TGGATTCGTTTTAACGGGCGGTCTATGTTATTTTCTGCTTCTATTCCGCCTACTTCCCTGGCTGCGGCTGCCACGGCCTT
GGATATTTTGATCGCCGAGCCCTGGCGGGTACAAAAGCTCCACGAAAATGCCCAATATTGGCAACGGGGGTTACAGTCCC
TTGGCTTTACGGTCGGTACCGCCCAAACGCCGATTATTACGGTACACATTGGCGATGATTTTAAATGTATGCAGTTCTGT
AAGGCCCTACTAGAGGCAGGAGTTTATGTGAATGCAGCGGTGTATCCGGCGGTGCCTCGTAATAAAGCCGCCCTCCGGAC
CAGTGTGATGGCGACCCACACCCAGGAACATTTAGACAAAGCCCTCGCAATTTTTGCGGAAGTCGGTCAGCAATTTCTGG
CTGGGGCTGAATAG

Upstream 100 bases:

>100_bases
GGATTGACAACATTAGGCTATATTTCTGCATAACAAAATTAGAAAACTCCTTTATTATTCCTTAAGGTCAGGCTCCACAA
CTGTTGCGTCCCCTTAGCTT

Downstream 100 bases:

>100_bases
ATGCGACACGCAATTATTACGGGGGGATCGAGTGGGATTGGTTTGGCGATCGCCTGTCAATTAGCTCAACAGGGGAATGT
CAATCTTTCAATCATTGCCC

Product: AMP-binding enzyme

Products: Acetyl-CoA; Glycine [C]

Alternate protein names: Acyl-CoA synthetase [H]

Number of amino acids: Translated: 1097; Mature: 1097

Protein sequence:

>1097_residues
MIYCFMTFLQHSIQAQASLLDILNERARSQPNAQAYVFLENGETESGHLTYQELATQAKAIASHLTPWRGERALLLYPSG
LAFITAFLGCLYAGVIAVPVYPPKRNQKLSRLLAIADNAQAELALTTEALLGDIQQRFAQAEQFQDLTFLATDTLKQAPQ
GFKPQTIQGDDLAFLQYTSGSTGTPKGVMVSHRNILHNQRLIQTAFGHSEKSIGVGWLPLFHDMGLIGHVLQPLYVGFPS
ILMPPVAFLTNPRRWLQAIAKYRATTSGGPNFAYDLCVDRLTDSDLADLDLSSWNLAYSGAEPVRAATLEKFNQKFAPCG
FRPEAFYPCYGMAEATLFITGGDKQQAPITTSSSEESDNLFVSCGQPYHDTQVAIVDPESFAPCPEGTTGEVWVRGDSVA
RGYWNAPIATQETFTATLNHHQKSFLRTGDLGFIAAGELFITGRLKDLIIVRGKNHYPHDIELTAQQSHPALRENCGAAF
TVEIDGTERLMLVQEVKRTFLRNLDVEAIAQKIRQTIAANHELQTYGIILIKTGSIPKTSSGKIQRHRCRQAFLADELMV
VGRSVLGEVDHASAQSFNPPQKQQPSQPTTDLIKPLREQLAQALSLPLDTIQDDQPIAALGLDSVQVVEIKHYIEQKFDL
IVPLEKFFEDLTVAQLAQDILTLANLPQESQHHQNGHLPQATQLEAEGIDLDQRLRLAYKPSRNVLDKAREFNLPDQLRA
NDLLPYFRALERNEGATCIFEGRQLIMLGSNNYLGLTADVRVREATAKAALEEGPSLTGSRLLNGSTRQHREFERKLAAF
VGHEDALVFTTGYQANLGFISALMNENTTMILDSEAHACIYDGAFMSRCRVVQYQHNDLQDLEQKLIQVTPESATMVTID
GLYSMTGDIAPLPEIRQLCDRHGATLAVDDAHALGVLGKTGRGTEEHFGMIDSSDILCGTFSKSLASIGGWVAAEAKVID
WIRFNGRSMLFSASIPPTSLAAAATALDILIAEPWRVQKLHENAQYWQRGLQSLGFTVGTAQTPIITVHIGDDFKCMQFC
KALLEAGVYVNAAVYPAVPRNKAALRTSVMATHTQEHLDKALAIFAEVGQQFLAGAE

Sequences:

>Translated_1097_residues
MIYCFMTFLQHSIQAQASLLDILNERARSQPNAQAYVFLENGETESGHLTYQELATQAKAIASHLTPWRGERALLLYPSG
LAFITAFLGCLYAGVIAVPVYPPKRNQKLSRLLAIADNAQAELALTTEALLGDIQQRFAQAEQFQDLTFLATDTLKQAPQ
GFKPQTIQGDDLAFLQYTSGSTGTPKGVMVSHRNILHNQRLIQTAFGHSEKSIGVGWLPLFHDMGLIGHVLQPLYVGFPS
ILMPPVAFLTNPRRWLQAIAKYRATTSGGPNFAYDLCVDRLTDSDLADLDLSSWNLAYSGAEPVRAATLEKFNQKFAPCG
FRPEAFYPCYGMAEATLFITGGDKQQAPITTSSSEESDNLFVSCGQPYHDTQVAIVDPESFAPCPEGTTGEVWVRGDSVA
RGYWNAPIATQETFTATLNHHQKSFLRTGDLGFIAAGELFITGRLKDLIIVRGKNHYPHDIELTAQQSHPALRENCGAAF
TVEIDGTERLMLVQEVKRTFLRNLDVEAIAQKIRQTIAANHELQTYGIILIKTGSIPKTSSGKIQRHRCRQAFLADELMV
VGRSVLGEVDHASAQSFNPPQKQQPSQPTTDLIKPLREQLAQALSLPLDTIQDDQPIAALGLDSVQVVEIKHYIEQKFDL
IVPLEKFFEDLTVAQLAQDILTLANLPQESQHHQNGHLPQATQLEAEGIDLDQRLRLAYKPSRNVLDKAREFNLPDQLRA
NDLLPYFRALERNEGATCIFEGRQLIMLGSNNYLGLTADVRVREATAKAALEEGPSLTGSRLLNGSTRQHREFERKLAAF
VGHEDALVFTTGYQANLGFISALMNENTTMILDSEAHACIYDGAFMSRCRVVQYQHNDLQDLEQKLIQVTPESATMVTID
GLYSMTGDIAPLPEIRQLCDRHGATLAVDDAHALGVLGKTGRGTEEHFGMIDSSDILCGTFSKSLASIGGWVAAEAKVID
WIRFNGRSMLFSASIPPTSLAAAATALDILIAEPWRVQKLHENAQYWQRGLQSLGFTVGTAQTPIITVHIGDDFKCMQFC
KALLEAGVYVNAAVYPAVPRNKAALRTSVMATHTQEHLDKALAIFAEVGQQFLAGAE
>Mature_1097_residues
MIYCFMTFLQHSIQAQASLLDILNERARSQPNAQAYVFLENGETESGHLTYQELATQAKAIASHLTPWRGERALLLYPSG
LAFITAFLGCLYAGVIAVPVYPPKRNQKLSRLLAIADNAQAELALTTEALLGDIQQRFAQAEQFQDLTFLATDTLKQAPQ
GFKPQTIQGDDLAFLQYTSGSTGTPKGVMVSHRNILHNQRLIQTAFGHSEKSIGVGWLPLFHDMGLIGHVLQPLYVGFPS
ILMPPVAFLTNPRRWLQAIAKYRATTSGGPNFAYDLCVDRLTDSDLADLDLSSWNLAYSGAEPVRAATLEKFNQKFAPCG
FRPEAFYPCYGMAEATLFITGGDKQQAPITTSSSEESDNLFVSCGQPYHDTQVAIVDPESFAPCPEGTTGEVWVRGDSVA
RGYWNAPIATQETFTATLNHHQKSFLRTGDLGFIAAGELFITGRLKDLIIVRGKNHYPHDIELTAQQSHPALRENCGAAF
TVEIDGTERLMLVQEVKRTFLRNLDVEAIAQKIRQTIAANHELQTYGIILIKTGSIPKTSSGKIQRHRCRQAFLADELMV
VGRSVLGEVDHASAQSFNPPQKQQPSQPTTDLIKPLREQLAQALSLPLDTIQDDQPIAALGLDSVQVVEIKHYIEQKFDL
IVPLEKFFEDLTVAQLAQDILTLANLPQESQHHQNGHLPQATQLEAEGIDLDQRLRLAYKPSRNVLDKAREFNLPDQLRA
NDLLPYFRALERNEGATCIFEGRQLIMLGSNNYLGLTADVRVREATAKAALEEGPSLTGSRLLNGSTRQHREFERKLAAF
VGHEDALVFTTGYQANLGFISALMNENTTMILDSEAHACIYDGAFMSRCRVVQYQHNDLQDLEQKLIQVTPESATMVTID
GLYSMTGDIAPLPEIRQLCDRHGATLAVDDAHALGVLGKTGRGTEEHFGMIDSSDILCGTFSKSLASIGGWVAAEAKVID
WIRFNGRSMLFSASIPPTSLAAAATALDILIAEPWRVQKLHENAQYWQRGLQSLGFTVGTAQTPIITVHIGDDFKCMQFC
KALLEAGVYVNAAVYPAVPRNKAALRTSVMATHTQEHLDKALAIFAEVGQQFLAGAE

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI284448556, Length=342, Percent_Identity=35.672514619883, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI7657118, Length=342, Percent_Identity=35.672514619883, Blast_Score=228, Evalue=3e-59,
Organism=Homo sapiens, GI4758668, Length=365, Percent_Identity=30.6849315068493, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI119220554, Length=389, Percent_Identity=31.1053984575836, Blast_Score=181, Evalue=4e-45,
Organism=Homo sapiens, GI4502025, Length=356, Percent_Identity=30.3370786516854, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI40316939, Length=356, Percent_Identity=30.3370786516854, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI83977442, Length=349, Percent_Identity=28.6532951289398, Blast_Score=158, Evalue=3e-38,
Organism=Homo sapiens, GI83977440, Length=349, Percent_Identity=28.6532951289398, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI83977444, Length=349, Percent_Identity=28.6532951289398, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI5454084, Length=383, Percent_Identity=29.5039164490862, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI55749758, Length=593, Percent_Identity=27.9932546374368, Blast_Score=151, Evalue=4e-36,
Organism=Homo sapiens, GI44888818, Length=590, Percent_Identity=26.9491525423729, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI45827692, Length=608, Percent_Identity=25.9868421052632, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI225735629, Length=608, Percent_Identity=25.9868421052632, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI225735625, Length=629, Percent_Identity=24.9602543720191, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI45827694, Length=539, Percent_Identity=25.2319109461967, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI225735627, Length=512, Percent_Identity=25, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI45827696, Length=512, Percent_Identity=25, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI156151445, Length=575, Percent_Identity=24.3478260869565, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI45827698, Length=476, Percent_Identity=24.5798319327731, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1790046, Length=358, Percent_Identity=35.195530726257, Blast_Score=227, Evalue=3e-60,
Organism=Escherichia coli, GI1786993, Length=353, Percent_Identity=30.3116147308782, Blast_Score=163, Evalue=6e-41,
Organism=Escherichia coli, GI1788107, Length=588, Percent_Identity=26.7006802721088, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI145693145, Length=569, Percent_Identity=23.3743409490334, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71994529, Length=370, Percent_Identity=33.2432432432432, Blast_Score=222, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI32566772, Length=366, Percent_Identity=30.8743169398907, Blast_Score=177, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17560912, Length=357, Percent_Identity=28.0112044817927, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17560914, Length=357, Percent_Identity=28.0112044817927, Blast_Score=160, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71982617, Length=283, Percent_Identity=30.3886925795053, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71982625, Length=283, Percent_Identity=30.3886925795053, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193202679, Length=594, Percent_Identity=24.7474747474747, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17559526, Length=577, Percent_Identity=24.4367417677643, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994694, Length=500, Percent_Identity=24.2, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994690, Length=500, Percent_Identity=24.2, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994703, Length=500, Percent_Identity=24.2, Blast_Score=107, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17558820, Length=465, Percent_Identity=22.7956989247312, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560308, Length=561, Percent_Identity=23.7076648841355, Blast_Score=83, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320267, Length=367, Percent_Identity=32.1525885558583, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6320438, Length=438, Percent_Identity=27.6255707762557, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323954, Length=266, Percent_Identity=27.0676691729323, Blast_Score=118, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6319699, Length=533, Percent_Identity=26.6416510318949, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24662918, Length=351, Percent_Identity=32.7635327635328, Blast_Score=227, Evalue=3e-59,
Organism=Drosophila melanogaster, GI17137420, Length=384, Percent_Identity=31.7708333333333, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI17136286, Length=364, Percent_Identity=30.7692307692308, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24653280, Length=401, Percent_Identity=26.6832917705736, Blast_Score=147, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24653276, Length=401, Percent_Identity=26.6832917705736, Blast_Score=147, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24653278, Length=401, Percent_Identity=26.6832917705736, Blast_Score=147, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24654656, Length=599, Percent_Identity=24.0400667779633, Blast_Score=123, Evalue=8e-28,
Organism=Drosophila melanogaster, GI18859661, Length=402, Percent_Identity=27.8606965174129, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24581924, Length=430, Percent_Identity=26.046511627907, Blast_Score=100, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 2.3.1.29 [C]

Molecular weight: Translated: 120858; Mature: 120858

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50075 ACP_DOMAIN ; PS00599 AA_TRANSFER_CLASS_2 ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYCFMTFLQHSIQAQASLLDILNERARSQPNAQAYVFLENGETESGHLTYQELATQAKA
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEHHHHHHHHHH
IASHLTPWRGERALLLYPSGLAFITAFLGCLYAGVIAVPVYPPKRNQKLSRLLAIADNAQ
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCC
AELALTTEALLGDIQQRFAQAEQFQDLTFLATDTLKQAPQGFKPQTIQGDDLAFLQYTSG
CEEEEHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHCCCCCCCCCCCCCCEEEEEEECC
STGTPKGVMVSHRNILHNQRLIQTAFGHSEKSIGVGWLPLFHDMGLIGHVLQPLYVGFPS
CCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
ILMPPVAFLTNPRRWLQAIAKYRATTSGGPNFAYDLCVDRLTDSDLADLDLSSWNLAYSG
HHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECC
AEPVRAATLEKFNQKFAPCGFRPEAFYPCYGMAEATLFITGGDKQQAPITTSSSEESDNL
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
FVSCGQPYHDTQVAIVDPESFAPCPEGTTGEVWVRGDSVARGYWNAPIATQETFTATLNH
EEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCEECCCCCCCCCCCHHHHHHHHH
HQKSFLRTGDLGFIAAGELFITGRLKDLIIVRGKNHYPHDIELTAQQSHPALRENCGAAF
HHHHHHHCCCCCEEEECCEEEEECCEEEEEEECCCCCCCCEEEEECCCCCHHHHCCCCEE
TVEIDGTERLMLVQEVKRTFLRNLDVEAIAQKIRQTIAANHELQTYGIILIKTGSIPKTS
EEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCC
SGKIQRHRCRQAFLADELMVVGRSVLGEVDHASAQSFNPPQKQQPSQPTTDLIKPLREQL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AQALSLPLDTIQDDQPIAALGLDSVQVVEIKHYIEQKFDLIVPLEKFFEDLTVAQLAQDI
HHHHCCCHHHCCCCCCEEEECCCCEEEHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHH
LTLANLPQESQHHQNGHLPQATQLEAEGIDLDQRLRLAYKPSRNVLDKAREFNLPDQLRA
HHHHCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHEEECCCHHHHHHHHHCCCCHHHCH
NDLLPYFRALERNEGATCIFEGRQLIMLGSNNYLGLTADVRVREATAKAALEEGPSLTGS
HHHHHHHHHHHCCCCCEEEECCCEEEEEECCCEEEEEECCEEHHHHHHHHHHCCCCCCHH
RLLNGSTRQHREFERKLAAFVGHEDALVFTTGYQANLGFISALMNENTTMILDSEAHACI
HHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCEEE
YDGAFMSRCRVVQYQHNDLQDLEQKLIQVTPESATMVTIDGLYSMTGDIAPLPEIRQLCD
ECCHHHHHHEEEEECCCCHHHHHHHHHEECCCCCEEEEECCHHHCCCCCCCCHHHHHHHH
RHGATLAVDDAHALGVLGKTGRGTEEHFGMIDSSDILCGTFSKSLASIGGWVAAEAKVID
HCCCEEEECCCHHHCCCCCCCCCCHHHCCCCCCCCCEEEHHHHHHHHHCCHHCCCHHEEE
WIRFNGRSMLFSASIPPTSLAAAATALDILIAEPWRVQKLHENAQYWQRGLQSLGFTVGT
EEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECC
AQTPIITVHIGDDFKCMQFCKALLEAGVYVNAAVYPAVPRNKAALRTSVMATHTQEHLDK
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ALAIFAEVGQQFLAGAE
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIYCFMTFLQHSIQAQASLLDILNERARSQPNAQAYVFLENGETESGHLTYQELATQAKA
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEHHHHHHHHHH
IASHLTPWRGERALLLYPSGLAFITAFLGCLYAGVIAVPVYPPKRNQKLSRLLAIADNAQ
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCC
AELALTTEALLGDIQQRFAQAEQFQDLTFLATDTLKQAPQGFKPQTIQGDDLAFLQYTSG
CEEEEHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHCCCCCCCCCCCCCCEEEEEEECC
STGTPKGVMVSHRNILHNQRLIQTAFGHSEKSIGVGWLPLFHDMGLIGHVLQPLYVGFPS
CCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
ILMPPVAFLTNPRRWLQAIAKYRATTSGGPNFAYDLCVDRLTDSDLADLDLSSWNLAYSG
HHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECC
AEPVRAATLEKFNQKFAPCGFRPEAFYPCYGMAEATLFITGGDKQQAPITTSSSEESDNL
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
FVSCGQPYHDTQVAIVDPESFAPCPEGTTGEVWVRGDSVARGYWNAPIATQETFTATLNH
EEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCEECCCCCCCCCCCHHHHHHHHH
HQKSFLRTGDLGFIAAGELFITGRLKDLIIVRGKNHYPHDIELTAQQSHPALRENCGAAF
HHHHHHHCCCCCEEEECCEEEEECCEEEEEEECCCCCCCCEEEEECCCCCHHHHCCCCEE
TVEIDGTERLMLVQEVKRTFLRNLDVEAIAQKIRQTIAANHELQTYGIILIKTGSIPKTS
EEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCC
SGKIQRHRCRQAFLADELMVVGRSVLGEVDHASAQSFNPPQKQQPSQPTTDLIKPLREQL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AQALSLPLDTIQDDQPIAALGLDSVQVVEIKHYIEQKFDLIVPLEKFFEDLTVAQLAQDI
HHHHCCCHHHCCCCCCEEEECCCCEEEHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHH
LTLANLPQESQHHQNGHLPQATQLEAEGIDLDQRLRLAYKPSRNVLDKAREFNLPDQLRA
HHHHCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHEEECCCHHHHHHHHHCCCCHHHCH
NDLLPYFRALERNEGATCIFEGRQLIMLGSNNYLGLTADVRVREATAKAALEEGPSLTGS
HHHHHHHHHHHCCCCCEEEECCCEEEEEECCCEEEEEECCEEHHHHHHHHHHCCCCCCHH
RLLNGSTRQHREFERKLAAFVGHEDALVFTTGYQANLGFISALMNENTTMILDSEAHACI
HHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCEEE
YDGAFMSRCRVVQYQHNDLQDLEQKLIQVTPESATMVTIDGLYSMTGDIAPLPEIRQLCD
ECCHHHHHHEEEEECCCCHHHHHHHHHEECCCCCEEEEECCHHHCCCCCCCCHHHHHHHH
RHGATLAVDDAHALGVLGKTGRGTEEHFGMIDSSDILCGTFSKSLASIGGWVAAEAKVID
HCCCEEEECCCHHHCCCCCCCCCCHHHCCCCCCCCCEEEHHHHHHHHHCCHHCCCHHEEE
WIRFNGRSMLFSASIPPTSLAAAATALDILIAEPWRVQKLHENAQYWQRGLQSLGFTVGT
EEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECC
AQTPIITVHIGDDFKCMQFCKALLEAGVYVNAAVYPAVPRNKAALRTSVMATHTQEHLDK
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ALAIFAEVGQQFLAGAE
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal 5-phosphate mol per mol subunit, enzyme, [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 12 {butyryl-CoA}} 0.08 {propionyl-CoA}} 0.059 {acetyl-CoA}} [C]

Substrates: L-2-Amino-3-oxobutanoate; Coenzyme A [C]

Specific reaction: L-2-Amino-3-oxobutanoate + Coenzyme A --> Acetyl-CoA + Glycine [C]

General reaction: Acyl group transfer [C]

Inhibitor: 1, 2-Cyclohexanedione; 2, 3-Butanedione; 4-(Oxoacetyl) phenoxyacetic acid; Aminomalonic acid; Aminomethyl phosphonic acid; Aminooxyacetate; Ba2+; Ca2+; Cd2+; CoA; Cu2+; DTT; Glutathione; Hg2+; Hydroxy l amine; IAA; L-Cysteine; Mn2+; PCMB, NEM, glycinemeth

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]