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The map label for this gene is cyaD [H]

Identifier: 170078511

GI number: 170078511

Start: 1992044

End: 1993597

Strand: Reverse

Name: cyaD [H]

Synonym: SYNPCC7002_A1906

Alternate gene names: 170078511

Gene position: 1993597-1992044 (Counterclockwise)

Preceding gene: 170078512

Following gene: 170078509

Centisome position: 66.28

GC content: 51.8

Gene sequence:

>1554_bases
ATGACCCAAATTTCCCGGTACCACGCCCGGATCAAACGGCGGCAACAGGCTTGGATTTTAGAGGACTTGGGCAGCACCAA
TGGCACATATCTCAATCACGTCCGGATTACTGAGCCCCAAACGATCCGCCAAGGAGATCTAATTCGTCTTGGCCATGCCT
CAATTTTAGTCACGTTCCAGAATGTGACCCTCGATGAAACGACAGATCTACAGGCTGACCAATGGGGATCGGGGCGCACC
ATTCTCCGTAACGCCGAAGATCTCAAGGAGCAATGGCTACAGGGGGAAGAAGGCTATGGTCATCAGCCCCACACGGAAAC
GGCGATCGCCCGCCTTAAGGAGTTGGTGGACATTGTGAAACAACTTAGTTCTGCCGAATCCATTGAAGCTATTTTTCGCC
TGACCCGGAATGTTATTTTTCAGGAATTGCCAGGCTTAGAACGGCTGGCGCTGCTCATTGATATTCGGGGCAATGGCAAA
TTAGAACTCCTCAGTGCTGCGGCCCAGAGTCTCCCGGATAATCACCCGGCCATTCGCACCAGTGCTTGGATTAGTCAATC
GGTCTGCCAAAAGGTTTTTAAAGAAAGGGTTGCCCTCAAATCCGTAGATGCCCAGAGCGACCAGCGCTTTGCAGGGGAAG
ATAGCATTTTGGCAAAGGGGATTCGAGGAGTGTTGGCGGTGCCCCTATGGGATCAAACAAAAGTGGTGGGGGTTCTGTAT
GGTGATGCCCACTTGAAGTTAGATGAATCAGAACCATTAACCGATGATGATTTAAGTTTTTTTTCGACCATTGGTCATCT
GTTGGCGGCCAGTGTGCAACGGTGGTTGCTGAGCCGTCGTCTCCAGGAACAGGCTCAAATTCGCCAAAAACTAGAGCGTT
ACCATTCGCCTGCGGTGGTACATCAATTAATTTCGGTGGGGGCGTTAAAAAATGGGCGACTCCCCCCTAGGGAAGCGGAA
ATCAGTATTTTATTTGCAGATATCGTTAATTTTACGCCCATTGCGGAGCAGTCTTCCCCCAGTGCCATTGCGGATTTGCT
GAACGTTTTTTTTGAGGAGATGCTCCATTCGGTGTTTGCCCAAGGGGGAACCCTCGATAAGTTTATTGGCGACTGCATTA
TGGCGTTTTTTGGGGCACCAGAACCCCAGATCGATCATGCTGAACGGGCGATCGCCACCGCCATGGGCATGCTCAACCGC
CTTGATCAACTAAATTTACAAAATATTTGGCCCCAACCGATTCAACTGCGGGTTGCGGTAAATAGCGGCAAGGCTTTTGT
GGGCGATGTGGGCAGCTCCCAGCGGGTAGACTACACGGTTCTGGGGGGAACGGTGAATCTTGCGGCCCGCCTTGAGACCA
TTTGTCCACCAGGGGAATGTGTGATCACCGATGCGACATATCAAGCGATTGGCGATCGCCACCAGGATTTATTTATTCCC
ATGGGGGCCGGGCGATTTAAAGGCATTGACCGCCCCATCCAGGTTTACCGTACCCAACGGCACCGCCACCCCAAACCGCT
ACCGTTAAAAAGCACCGAGGTTTCCAGCTCCTAG

Upstream 100 bases:

>100_bases
ACTCCGCATCCAAGCTGAGGGCTACCCAGAACGTATTGTGGTGGTCGATCAAGGGGAGTTTGTGATCGGTCGCTTGCCTG
AATGTAGTCTCTCGCTACAG

Downstream 100 bases:

>100_bases
GTTTTTGGCATTTCATCACGGCTCTGCAAAATAAATTCGGCGATCGCCAAATCTCCTGGCGTCGTAATTTTGAGGTTTGT
TTCTTCCCCAGAGACAATTT

Product: adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTQISRYHARIKRRQQAWILEDLGSTNGTYLNHVRITEPQTIRQGDLIRLGHASILVTFQNVTLDETTDLQADQWGSGRT
ILRNAEDLKEQWLQGEEGYGHQPHTETAIARLKELVDIVKQLSSAESIEAIFRLTRNVIFQELPGLERLALLIDIRGNGK
LELLSAAAQSLPDNHPAIRTSAWISQSVCQKVFKERVALKSVDAQSDQRFAGEDSILAKGIRGVLAVPLWDQTKVVGVLY
GDAHLKLDESEPLTDDDLSFFSTIGHLLAASVQRWLLSRRLQEQAQIRQKLERYHSPAVVHQLISVGALKNGRLPPREAE
ISILFADIVNFTPIAEQSSPSAIADLLNVFFEEMLHSVFAQGGTLDKFIGDCIMAFFGAPEPQIDHAERAIATAMGMLNR
LDQLNLQNIWPQPIQLRVAVNSGKAFVGDVGSSQRVDYTVLGGTVNLAARLETICPPGECVITDATYQAIGDRHQDLFIP
MGAGRFKGIDRPIQVYRTQRHRHPKPLPLKSTEVSSS

Sequences:

>Translated_517_residues
MTQISRYHARIKRRQQAWILEDLGSTNGTYLNHVRITEPQTIRQGDLIRLGHASILVTFQNVTLDETTDLQADQWGSGRT
ILRNAEDLKEQWLQGEEGYGHQPHTETAIARLKELVDIVKQLSSAESIEAIFRLTRNVIFQELPGLERLALLIDIRGNGK
LELLSAAAQSLPDNHPAIRTSAWISQSVCQKVFKERVALKSVDAQSDQRFAGEDSILAKGIRGVLAVPLWDQTKVVGVLY
GDAHLKLDESEPLTDDDLSFFSTIGHLLAASVQRWLLSRRLQEQAQIRQKLERYHSPAVVHQLISVGALKNGRLPPREAE
ISILFADIVNFTPIAEQSSPSAIADLLNVFFEEMLHSVFAQGGTLDKFIGDCIMAFFGAPEPQIDHAERAIATAMGMLNR
LDQLNLQNIWPQPIQLRVAVNSGKAFVGDVGSSQRVDYTVLGGTVNLAARLETICPPGECVITDATYQAIGDRHQDLFIP
MGAGRFKGIDRPIQVYRTQRHRHPKPLPLKSTEVSSS
>Mature_516_residues
TQISRYHARIKRRQQAWILEDLGSTNGTYLNHVRITEPQTIRQGDLIRLGHASILVTFQNVTLDETTDLQADQWGSGRTI
LRNAEDLKEQWLQGEEGYGHQPHTETAIARLKELVDIVKQLSSAESIEAIFRLTRNVIFQELPGLERLALLIDIRGNGKL
ELLSAAAQSLPDNHPAIRTSAWISQSVCQKVFKERVALKSVDAQSDQRFAGEDSILAKGIRGVLAVPLWDQTKVVGVLYG
DAHLKLDESEPLTDDDLSFFSTIGHLLAASVQRWLLSRRLQEQAQIRQKLERYHSPAVVHQLISVGALKNGRLPPREAEI
SILFADIVNFTPIAEQSSPSAIADLLNVFFEEMLHSVFAQGGTLDKFIGDCIMAFFGAPEPQIDHAERAIATAMGMLNRL
DQLNLQNIWPQPIQLRVAVNSGKAFVGDVGSSQRVDYTVLGGTVNLAARLETICPPGECVITDATYQAIGDRHQDLFIPM
GAGRFKGIDRPIQVYRTQRHRHPKPLPLKSTEVSSS

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Homo sapiens, GI50959205, Length=158, Percent_Identity=32.2784810126582, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4504211, Length=167, Percent_Identity=29.3413173652695, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI222080083, Length=144, Percent_Identity=31.9444444444444, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4557255, Length=159, Percent_Identity=29.559748427673, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989822, Length=199, Percent_Identity=28.1407035175879, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71989805, Length=199, Percent_Identity=28.1407035175879, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508769, Length=182, Percent_Identity=29.1208791208791, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17551720, Length=147, Percent_Identity=30.6122448979592, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71990146, Length=181, Percent_Identity=29.8342541436464, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17561810, Length=184, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983004, Length=165, Percent_Identity=27.8787878787879, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534659, Length=174, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17534657, Length=155, Percent_Identity=25.1612903225806, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17557192, Length=147, Percent_Identity=27.891156462585, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI62473752, Length=231, Percent_Identity=27.7056277056277, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17137448, Length=231, Percent_Identity=27.7056277056277, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221330470, Length=230, Percent_Identity=31.304347826087, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221330468, Length=230, Percent_Identity=31.304347826087, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI161078020, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62484298, Length=227, Percent_Identity=28.1938325991189, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI62484477, Length=207, Percent_Identity=28.5024154589372, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI116008008, Length=227, Percent_Identity=28.1938325991189, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281366320, Length=157, Percent_Identity=28.6624203821656, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI161084260, Length=183, Percent_Identity=26.775956284153, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583978, Length=159, Percent_Identity=25.1572327044025, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642014, Length=213, Percent_Identity=27.2300469483568, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574512, Length=199, Percent_Identity=28.643216080402, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076872, Length=199, Percent_Identity=28.643216080402, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583980, Length=147, Percent_Identity=27.2108843537415, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 57510; Mature: 57379

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50006 FHA_DOMAIN ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQISRYHARIKRRQQAWILEDLGSTNGTYLNHVRITEPQTIRQGDLIRLGHASILVTFQ
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEEEE
NVTLDETTDLQADQWGSGRTILRNAEDLKEQWLQGEEGYGHQPHTETAIARLKELVDIVK
CCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QLSSAESIEAIFRLTRNVIFQELPGLERLALLIDIRGNGKLELLSAAAQSLPDNHPAIRT
HHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCHH
SAWISQSVCQKVFKERVALKSVDAQSDQRFAGEDSILAKGIRGVLAVPLWDQTKVVGVLY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCEEEEEEE
GDAHLKLDESEPLTDDDLSFFSTIGHLLAASVQRWLLSRRLQEQAQIRQKLERYHSPAVV
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
HQLISVGALKNGRLPPREAEISILFADIVNFTPIAEQSSPSAIADLLNVFFEEMLHSVFA
HHHHHHCCCCCCCCCCCCCHHEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QGGTLDKFIGDCIMAFFGAPEPQIDHAERAIATAMGMLNRLDQLNLQNIWPQPIQLRVAV
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEE
NSGKAFVGDVGSSQRVDYTVLGGTVNLAARLETICPPGECVITDATYQAIGDRHQDLFIP
ECCCEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCEEEEE
MGAGRFKGIDRPIQVYRTQRHRHPKPLPLKSTEVSSS
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQISRYHARIKRRQQAWILEDLGSTNGTYLNHVRITEPQTIRQGDLIRLGHASILVTFQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEEEE
NVTLDETTDLQADQWGSGRTILRNAEDLKEQWLQGEEGYGHQPHTETAIARLKELVDIVK
CCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QLSSAESIEAIFRLTRNVIFQELPGLERLALLIDIRGNGKLELLSAAAQSLPDNHPAIRT
HHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCHH
SAWISQSVCQKVFKERVALKSVDAQSDQRFAGEDSILAKGIRGVLAVPLWDQTKVVGVLY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCEEEEEEE
GDAHLKLDESEPLTDDDLSFFSTIGHLLAASVQRWLLSRRLQEQAQIRQKLERYHSPAVV
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
HQLISVGALKNGRLPPREAEISILFADIVNFTPIAEQSSPSAIADLLNVFFEEMLHSVFA
HHHHHHCCCCCCCCCCCCCHHEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QGGTLDKFIGDCIMAFFGAPEPQIDHAERAIATAMGMLNRLDQLNLQNIWPQPIQLRVAV
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEEE
NSGKAFVGDVGSSQRVDYTVLGGTVNLAARLETICPPGECVITDATYQAIGDRHQDLFIP
ECCCEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCHHHHHCCCCCEEEEE
MGAGRFKGIDRPIQVYRTQRHRHPKPLPLKSTEVSSS
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]