| Definition | Synechococcus sp. PCC 7002 chromosome, complete genome. |
|---|---|
| Accession | NC_010475 |
| Length | 3,008,047 |
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The map label for this gene is gmk [H]
Identifier: 170078452
GI number: 170078452
Start: 1935874
End: 1936428
Strand: Direct
Name: gmk [H]
Synonym: SYNPCC7002_A1846
Alternate gene names: 170078452
Gene position: 1935874-1936428 (Clockwise)
Preceding gene: 170078451
Following gene: 170078453
Centisome position: 64.36
GC content: 48.83
Gene sequence:
>555_bases ATGACCACCCCCGGAAAATTAATTGTCCTCACAGGGCCAAGTGGTGTTGGTAAAGGAACCTTAGTTCGTTCTTTACTACC GCGCCACCAAAATTTATTTCTCTCGATCTCAGCAACAACCCGTCAGCCCCGCCCTGGAGAAGTGGATGGGCAAGACTATT TTTTCAAAACCCGTGAACAATTTGAGGCGATGATCGCTGCGGGGGATCTCCTCGAATGGGCCGAGTATGCGGGAAATTAC TACGGCACCCCTCTGCCTCCGGTGAAAACACAAATTCAACAGGGAAACTTTGTCATCCTCGAAATCGAGGTCATTGGGGC CAACCAAGTTAAAGAAATCTATGCAGATGCCCTCAGAATTTTTATTTTGCCACCGTCCTTTGAAGAGTTAGAACAGCGGC TGCGGGGACGGGGTAATGATCCAGAAGCGGCGATCGCCAAACGGCTCGTCCGGGCAAAAGAAGAATTGGCCATGAGCCAT GAGTTCGACCATGAAATTGTCAATGACGACCTAGAAACAGCCTTAACAGAACTCGAAAAAGTGATTTTCAGCTAG
Upstream 100 bases:
>100_bases CAGAGACAGTGGCCCATCGCTTTGTTGTGCAAAAAGATCCCGCCATGGCGATGACCAAAGTTTAACGGTTGAGTTATCAT CTCCCGTCGCCGCCGAATCC
Downstream 100 bases:
>100_bases CCGAAACGCCACCGCTGCCAACTGAATCCATTACAATCAAACAAATAAGACATAAACAACAACGAGCTTACAGACCCCAT GATTCCAACCGTTATCGAAA
Product: guanylate kinase
Products: NA
Alternate protein names: GMP kinase [H]
Number of amino acids: Translated: 184; Mature: 183
Protein sequence:
>184_residues MTTPGKLIVLTGPSGVGKGTLVRSLLPRHQNLFLSISATTRQPRPGEVDGQDYFFKTREQFEAMIAAGDLLEWAEYAGNY YGTPLPPVKTQIQQGNFVILEIEVIGANQVKEIYADALRIFILPPSFEELEQRLRGRGNDPEAAIAKRLVRAKEELAMSH EFDHEIVNDDLETALTELEKVIFS
Sequences:
>Translated_184_residues MTTPGKLIVLTGPSGVGKGTLVRSLLPRHQNLFLSISATTRQPRPGEVDGQDYFFKTREQFEAMIAAGDLLEWAEYAGNY YGTPLPPVKTQIQQGNFVILEIEVIGANQVKEIYADALRIFILPPSFEELEQRLRGRGNDPEAAIAKRLVRAKEELAMSH EFDHEIVNDDLETALTELEKVIFS >Mature_183_residues TTPGKLIVLTGPSGVGKGTLVRSLLPRHQNLFLSISATTRQPRPGEVDGQDYFFKTREQFEAMIAAGDLLEWAEYAGNYY GTPLPPVKTQIQQGNFVILEIEVIGANQVKEIYADALRIFILPPSFEELEQRLRGRGNDPEAAIAKRLVRAKEELAMSHE FDHEIVNDDLETALTELEKVIFS
Specific function: Essential for recycling GMP and indirectly, cGMP [H]
COG id: COG0194
COG function: function code F; Guanylate kinase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 guanylate kinase-like domain [H]
Homologues:
Organism=Homo sapiens, GI226874833, Length=186, Percent_Identity=41.3978494623656, Blast_Score=143, Evalue=8e-35, Organism=Homo sapiens, GI4504221, Length=186, Percent_Identity=41.3978494623656, Blast_Score=143, Evalue=8e-35, Organism=Homo sapiens, GI226874831, Length=186, Percent_Identity=41.3978494623656, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI38570142, Length=178, Percent_Identity=34.2696629213483, Blast_Score=101, Evalue=4e-22, Organism=Homo sapiens, GI14780902, Length=188, Percent_Identity=30.8510638297872, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI21361598, Length=189, Percent_Identity=30.6878306878307, Blast_Score=81, Evalue=6e-16, Organism=Homo sapiens, GI4505237, Length=177, Percent_Identity=29.9435028248588, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI262118263, Length=176, Percent_Identity=30.1136363636364, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI262118259, Length=176, Percent_Identity=30.1136363636364, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI262118255, Length=177, Percent_Identity=29.9435028248588, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI52630447, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI111154074, Length=168, Percent_Identity=26.7857142857143, Blast_Score=73, Evalue=1e-13, Organism=Homo sapiens, GI186972120, Length=184, Percent_Identity=26.6304347826087, Blast_Score=69, Evalue=2e-12, Organism=Homo sapiens, GI186700629, Length=184, Percent_Identity=26.6304347826087, Blast_Score=69, Evalue=2e-12, Organism=Homo sapiens, GI186700627, Length=184, Percent_Identity=26.6304347826087, Blast_Score=69, Evalue=2e-12, Organism=Homo sapiens, GI21389483, Length=187, Percent_Identity=26.7379679144385, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI218505835, Length=59, Percent_Identity=55.9322033898305, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI155969695, Length=60, Percent_Identity=55, Blast_Score=66, Evalue=2e-11, Organism=Escherichia coli, GI1790080, Length=181, Percent_Identity=46.9613259668508, Blast_Score=162, Evalue=9e-42, Organism=Caenorhabditis elegans, GI193203132, Length=180, Percent_Identity=41.6666666666667, Blast_Score=136, Evalue=7e-33, Organism=Caenorhabditis elegans, GI17508835, Length=180, Percent_Identity=41.6666666666667, Blast_Score=135, Evalue=9e-33, Organism=Caenorhabditis elegans, GI71988041, Length=179, Percent_Identity=30.7262569832402, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71988048, Length=179, Percent_Identity=30.7262569832402, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17556244, Length=124, Percent_Identity=31.4516129032258, Blast_Score=67, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17557440, Length=183, Percent_Identity=28.9617486338798, Blast_Score=67, Evalue=6e-12, Organism=Saccharomyces cerevisiae, GI6320662, Length=181, Percent_Identity=44.7513812154696, Blast_Score=158, Evalue=5e-40, Organism=Drosophila melanogaster, GI21356141, Length=187, Percent_Identity=41.7112299465241, Blast_Score=129, Evalue=1e-30, Organism=Drosophila melanogaster, GI45554481, Length=177, Percent_Identity=32.7683615819209, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI161077626, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=9e-18, Organism=Drosophila melanogaster, GI45554489, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=1e-17, Organism=Drosophila melanogaster, GI24640542, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=1e-17, Organism=Drosophila melanogaster, GI116007136, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=1e-17, Organism=Drosophila melanogaster, GI85724806, Length=177, Percent_Identity=32.7683615819209, Blast_Score=86, Evalue=1e-17, Organism=Drosophila melanogaster, GI221330162, Length=184, Percent_Identity=31.5217391304348, Blast_Score=76, Evalue=1e-14, Organism=Drosophila melanogaster, GI221330166, Length=184, Percent_Identity=31.5217391304348, Blast_Score=76, Evalue=1e-14, Organism=Drosophila melanogaster, GI221330164, Length=184, Percent_Identity=31.5217391304348, Blast_Score=76, Evalue=1e-14, Organism=Drosophila melanogaster, GI45551002, Length=174, Percent_Identity=31.6091954022989, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI161078485, Length=180, Percent_Identity=27.2222222222222, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648810, Length=180, Percent_Identity=27.2222222222222, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI85816106, Length=174, Percent_Identity=31.6091954022989, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI281362232, Length=180, Percent_Identity=27.2222222222222, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI85816281, Length=174, Percent_Identity=31.6091954022989, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI281362230, Length=180, Percent_Identity=27.2222222222222, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24648808, Length=180, Percent_Identity=27.2222222222222, Blast_Score=68, Evalue=3e-12, Organism=Drosophila melanogaster, GI161078487, Length=180, Percent_Identity=27.2222222222222, Blast_Score=68, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008144 - InterPro: IPR008145 - InterPro: IPR020590 - InterPro: IPR017665 [H]
Pfam domain/function: PF00625 Guanylate_kin [H]
EC number: =2.7.4.8 [H]
Molecular weight: Translated: 20585; Mature: 20454
Theoretical pI: Translated: 4.69; Mature: 4.69
Prosite motif: PS00856 GUANYLATE_KINASE_1 ; PS50052 GUANYLATE_KINASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTPGKLIVLTGPSGVGKGTLVRSLLPRHQNLFLSISATTRQPRPGEVDGQDYFFKTREQ CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH FEAMIAAGDLLEWAEYAGNYYGTPLPPVKTQIQQGNFVILEIEVIGANQVKEIYADALRI HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHEE FILPPSFEELEQRLRGRGNDPEAAIAKRLVRAKEELAMSHEFDHEIVNDDLETALTELEK EEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHH VIFS HHCC >Mature Secondary Structure TTPGKLIVLTGPSGVGKGTLVRSLLPRHQNLFLSISATTRQPRPGEVDGQDYFFKTREQ CCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH FEAMIAAGDLLEWAEYAGNYYGTPLPPVKTQIQQGNFVILEIEVIGANQVKEIYADALRI HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHEE FILPPSFEELEQRLRGRGNDPEAAIAKRLVRAKEELAMSHEFDHEIVNDDLETALTELEK EEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHH VIFS HHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA