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The map label for this gene is dnaX [H]

Identifier: 170078311

GI number: 170078311

Start: 1787854

End: 1790082

Strand: Reverse

Name: dnaX [H]

Synonym: SYNPCC7002_A1704

Alternate gene names: 170078311

Gene position: 1790082-1787854 (Counterclockwise)

Preceding gene: 170078316

Following gene: 170078310

Centisome position: 59.51

GC content: 53.79

Gene sequence:

>2229_bases
ATGGCCTACGAACCGCTCCACCACAAATATCGTCCCCAGACTTTTGCGCAGTTGGTTGGTCAAGAGGCGATCGCCACAAC
CTTGAGTAATGCCCTCGAACAGCGACGCATTGCCCCAGCCTATTTGTTCTCAGGGCCACGGGGGACGGGGAAAACCTCCA
GCGCGCGGATCTTGGCTAAGTCTCTAAATTGTCTAAATGCAGCCCAACCGACGCCCCACCCTTGTGGCGAGTGTGAAGTT
TGTCGGGCGATCGCCAACGGGTCAGCCTTAGATGTGATTGAAATTGACGCGGCGAGTAATACGGGCGTTGATAATATTCG
CGAACTCATCGAGCGATCGCAGTTTGCCCCAGTGCAATGTCGCTACAAAGTTTATGTCATCGACGAATGCCATATGTTGA
GTGTGGCAGCGTTCAATGCTTTATTGAAAACCCTCGAAGAACCCCCTGCCCACGTTGTATTTGTCCTGGCAACAACGGAT
CCCCAAAGGGTTTTACCAACGATTATTTCCCGCTGTCAACGGTTTGACTATCGGCGTATTCCCCTCGATGCGATGGTCGC
CCACCTACGGAAAATTGCCCATTTAGAAAATATCGATATTCCCCTCGAATCGGTAACGTTAATTGCGCAAATTGCCAACG
GAGGGTTGCGGGATGCAGAAAGTTTATTGGATCAACTGAGTTTATTGTCCGGTGAAATTACCCCTGATAAGGTCTGGGAT
TTAGTGGGGGCCGTGCCGGAGCGGGATCTATTGCAATTACTCCAAGTGATTCACAGCAATGATCCAGAGGCAGTTATTCA
ACAATGCCGGAGCCTGTTAAACCGAGGTCGGGAACCCCTGGTTGTGCTGCAAAATTTGGCGAGCTTTTATCTAAATTTGC
TCATTGCCAAAACTGCCCCCCAACGGGGAGATCTGATCGCTGTGACCCAACCGACTTGGGAAATCCTGTGCCAGGAAGCC
AACCAGTGGGAGCTTTCCACCATTTTGCAGGGACAGCAACACCTCAAAGAAAGTGAATATCAACTCAAAAATACGACCCA
ACCGCGTCTGTGGTTAGAAATTACCCTGTTGGGATTACTTCCCGCTGCTTTTGGACAGACCCAAACTACTCGAACCGCGA
CCACTCCTTTAAATACTCAGATCAATCTACAAACGCAGCCTACCGCGACACCGCCGACTTCTCCGCCACCTCCACAGGAC
ATCCCCCATCCCTTTGGGGAAACACCCCCTGCAACCAATGGCCACGGCTCTGGAACGCCCCCCTCTCCGGTAGACACTCA
AGTTCACCAAGTTCCTCCCAAACCCGAAGTTCCCCAAGTTCCGGCCCCTGTACCAGAAGCAAAGGCGATCGCCAAAGCGC
CACCGTCCCAGGATGTAATCCCTCCAACGGTTCAGCCCACCGAGCCACCCCCTTTATCACCGTCACCTCCTGCAACCACC
AGCCCGACAATTTCGGCCCTGGAACGGGAAGAATTGTGGCAAGGCATTGTGCGCCAACTGCCCCTGTTGAGCCAGTCTTT
GTTTCGAGACCATGGCAAACTGCTCCAGCTTACGGATCACAGCGCTCTCATCGGCATTAAAAGCGCCAACTTACTCAAAA
TTGCCAAAAATAAAACCCTCCAGCTTGAGGCGGCCTTTGAGAAAATCTGTGGCAACCCCCTTAAGGTGACCTTACAAGTG
GGCCATGGTTTAGAAAATGGCCAGGGAGGAACATCAGTAACCCCGATTTTATCTACGCCTGCACCAGCACCAACAGTTAT
TTCTCCGGCGCAAAATCCTATCGAGATGCCGCCGCCCCCGGTTGCGGAAACCCCGCAGCCCATGGCCCCACCGCCCCTAG
GGTCGCCAACCAAACCAGCACCAGATCCAAAACCTCCGGAACCAACACCAACGGCGCACCGCAAAGCGGATCTCGGAGAG
ATCACCCCGCCAGCCCCAGCGGTTCCTCCCCTCGTTGAGTCAGCATCAGCGTCTGAACCCACAGCCACAGCAGAGATCCC
AGAAACGACCGATGATATTCAGGCGATCGCCCAACAGTTTGCAGAATTGTTTGACGGAGAGGTGATCGAACTGACTCACT
TTGTCCCCCCAGAAGAAACGGACGTGCAGGTTGTGCTTCCTCCCGAACCCGAAAAACCCCCACCACCTGTTCCCGAACCG
CCGACCATCCCCGTTGTTCAAGGTCGTCCACCCGTGCCAGTGGCCCCAGACGATGAGATTCCGTTCTGA

Upstream 100 bases:

>100_bases
TATTAGACATTGGACGTTAGATATCGATTCTTTATCGTTGCTGCTGGATCCATAACTGTTTACTGATCGCCGTCCTTTAT
CGAATTTTTCGTTGTTTCCC

Downstream 100 bases:

>100_bases
GAACCTCGTATCATTGATGGTGATGTCTCTTGGATGAAGCCCCTATGACTTTACAGCGCACGCCCCTCCATGACCTCGCC
ATTGCAGCGGGTGCCAAATT

Product: DNA-directed DNA polymerase III chain dnaX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 742; Mature: 741

Protein sequence:

>742_residues
MAYEPLHHKYRPQTFAQLVGQEAIATTLSNALEQRRIAPAYLFSGPRGTGKTSSARILAKSLNCLNAAQPTPHPCGECEV
CRAIANGSALDVIEIDAASNTGVDNIRELIERSQFAPVQCRYKVYVIDECHMLSVAAFNALLKTLEEPPAHVVFVLATTD
PQRVLPTIISRCQRFDYRRIPLDAMVAHLRKIAHLENIDIPLESVTLIAQIANGGLRDAESLLDQLSLLSGEITPDKVWD
LVGAVPERDLLQLLQVIHSNDPEAVIQQCRSLLNRGREPLVVLQNLASFYLNLLIAKTAPQRGDLIAVTQPTWEILCQEA
NQWELSTILQGQQHLKESEYQLKNTTQPRLWLEITLLGLLPAAFGQTQTTRTATTPLNTQINLQTQPTATPPTSPPPPQD
IPHPFGETPPATNGHGSGTPPSPVDTQVHQVPPKPEVPQVPAPVPEAKAIAKAPPSQDVIPPTVQPTEPPPLSPSPPATT
SPTISALEREELWQGIVRQLPLLSQSLFRDHGKLLQLTDHSALIGIKSANLLKIAKNKTLQLEAAFEKICGNPLKVTLQV
GHGLENGQGGTSVTPILSTPAPAPTVISPAQNPIEMPPPPVAETPQPMAPPPLGSPTKPAPDPKPPEPTPTAHRKADLGE
ITPPAPAVPPLVESASASEPTATAEIPETTDDIQAIAQQFAELFDGEVIELTHFVPPEETDVQVVLPPEPEKPPPPVPEP
PTIPVVQGRPPVPVAPDDEIPF

Sequences:

>Translated_742_residues
MAYEPLHHKYRPQTFAQLVGQEAIATTLSNALEQRRIAPAYLFSGPRGTGKTSSARILAKSLNCLNAAQPTPHPCGECEV
CRAIANGSALDVIEIDAASNTGVDNIRELIERSQFAPVQCRYKVYVIDECHMLSVAAFNALLKTLEEPPAHVVFVLATTD
PQRVLPTIISRCQRFDYRRIPLDAMVAHLRKIAHLENIDIPLESVTLIAQIANGGLRDAESLLDQLSLLSGEITPDKVWD
LVGAVPERDLLQLLQVIHSNDPEAVIQQCRSLLNRGREPLVVLQNLASFYLNLLIAKTAPQRGDLIAVTQPTWEILCQEA
NQWELSTILQGQQHLKESEYQLKNTTQPRLWLEITLLGLLPAAFGQTQTTRTATTPLNTQINLQTQPTATPPTSPPPPQD
IPHPFGETPPATNGHGSGTPPSPVDTQVHQVPPKPEVPQVPAPVPEAKAIAKAPPSQDVIPPTVQPTEPPPLSPSPPATT
SPTISALEREELWQGIVRQLPLLSQSLFRDHGKLLQLTDHSALIGIKSANLLKIAKNKTLQLEAAFEKICGNPLKVTLQV
GHGLENGQGGTSVTPILSTPAPAPTVISPAQNPIEMPPPPVAETPQPMAPPPLGSPTKPAPDPKPPEPTPTAHRKADLGE
ITPPAPAVPPLVESASASEPTATAEIPETTDDIQAIAQQFAELFDGEVIELTHFVPPEETDVQVVLPPEPEKPPPPVPEP
PTIPVVQGRPPVPVAPDDEIPF
>Mature_741_residues
AYEPLHHKYRPQTFAQLVGQEAIATTLSNALEQRRIAPAYLFSGPRGTGKTSSARILAKSLNCLNAAQPTPHPCGECEVC
RAIANGSALDVIEIDAASNTGVDNIRELIERSQFAPVQCRYKVYVIDECHMLSVAAFNALLKTLEEPPAHVVFVLATTDP
QRVLPTIISRCQRFDYRRIPLDAMVAHLRKIAHLENIDIPLESVTLIAQIANGGLRDAESLLDQLSLLSGEITPDKVWDL
VGAVPERDLLQLLQVIHSNDPEAVIQQCRSLLNRGREPLVVLQNLASFYLNLLIAKTAPQRGDLIAVTQPTWEILCQEAN
QWELSTILQGQQHLKESEYQLKNTTQPRLWLEITLLGLLPAAFGQTQTTRTATTPLNTQINLQTQPTATPPTSPPPPQDI
PHPFGETPPATNGHGSGTPPSPVDTQVHQVPPKPEVPQVPAPVPEAKAIAKAPPSQDVIPPTVQPTEPPPLSPSPPATTS
PTISALEREELWQGIVRQLPLLSQSLFRDHGKLLQLTDHSALIGIKSANLLKIAKNKTLQLEAAFEKICGNPLKVTLQVG
HGLENGQGGTSVTPILSTPAPAPTVISPAQNPIEMPPPPVAETPQPMAPPPLGSPTKPAPDPKPPEPTPTAHRKADLGEI
TPPAPAVPPLVESASASEPTATAEIPETTDDIQAIAQQFAELFDGEVIELTHFVPPEETDVQVVLPPEPEKPPPPVPEPP
TIPVVQGRPPVPVAPDDEIPF

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=283, Percent_Identity=27.208480565371, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI31881687, Length=283, Percent_Identity=27.208480565371, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI6677723, Length=259, Percent_Identity=26.2548262548263, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI194306571, Length=255, Percent_Identity=26.2745098039216, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI194306567, Length=255, Percent_Identity=26.2745098039216, Blast_Score=86, Evalue=2e-16,
Organism=Escherichia coli, GI1786676, Length=301, Percent_Identity=43.5215946843854, Blast_Score=243, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71986063, Length=309, Percent_Identity=24.5954692556634, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17554730, Length=234, Percent_Identity=25.2136752136752, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17541988, Length=274, Percent_Identity=24.0875912408759, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322528, Length=311, Percent_Identity=24.4372990353698, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324039, Length=266, Percent_Identity=24.812030075188, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324478, Length=239, Percent_Identity=24.6861924686192, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI18859927, Length=281, Percent_Identity=27.0462633451957, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19921076, Length=257, Percent_Identity=24.9027237354086, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17647857, Length=287, Percent_Identity=23.6933797909408, Blast_Score=76, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 79986; Mature: 79855

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYEPLHHKYRPQTFAQLVGQEAIATTLSNALEQRRIAPAYLFSGPRGTGKTSSARILAK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCHHHHHHHH
SLNCLNAAQPTPHPCGECEVCRAIANGSALDVIEIDAASNTGVDNIRELIERSQFAPVQC
HHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEE
RYKVYVIDECHMLSVAAFNALLKTLEEPPAHVVFVLATTDPQRVLPTIISRCQRFDYRRI
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCC
PLDAMVAHLRKIAHLENIDIPLESVTLIAQIANGGLRDAESLLDQLSLLSGEITPDKVWD
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
LVGAVPERDLLQLLQVIHSNDPEAVIQQCRSLLNRGREPLVVLQNLASFYLNLLIAKTAP
HHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
QRGDLIAVTQPTWEILCQEANQWELSTILQGQQHLKESEYQLKNTTQPRLWLEITLLGLL
CCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHH
PAAFGQTQTTRTATTPLNTQINLQTQPTATPPTSPPPPQDIPHPFGETPPATNGHGSGTP
HHHCCCCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSPVDTQVHQVPPKPEVPQVPAPVPEAKAIAKAPPSQDVIPPTVQPTEPPPLSPSPPATT
CCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPTISALEREELWQGIVRQLPLLSQSLFRDHGKLLQLTDHSALIGIKSANLLKIAKNKTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCEEEECCCCCE
QLEAAFEKICGNPLKVTLQVGHGLENGQGGTSVTPILSTPAPAPTVISPAQNPIEMPPPP
EHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEECEEECCCCCCCCEECCCCCCCCCCCCC
VAETPQPMAPPPLGSPTKPAPDPKPPEPTPTAHRKADLGEITPPAPAVPPLVESASASEP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCC
TATAEIPETTDDIQAIAQQFAELFDGEVIELTHFVPPEETDVQVVLPPEPEKPPPPVPEP
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCC
PTIPVVQGRPPVPVAPDDEIPF
CCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYEPLHHKYRPQTFAQLVGQEAIATTLSNALEQRRIAPAYLFSGPRGTGKTSSARILAK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCHHHHHHHH
SLNCLNAAQPTPHPCGECEVCRAIANGSALDVIEIDAASNTGVDNIRELIERSQFAPVQC
HHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEE
RYKVYVIDECHMLSVAAFNALLKTLEEPPAHVVFVLATTDPQRVLPTIISRCQRFDYRRI
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCC
PLDAMVAHLRKIAHLENIDIPLESVTLIAQIANGGLRDAESLLDQLSLLSGEITPDKVWD
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
LVGAVPERDLLQLLQVIHSNDPEAVIQQCRSLLNRGREPLVVLQNLASFYLNLLIAKTAP
HHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
QRGDLIAVTQPTWEILCQEANQWELSTILQGQQHLKESEYQLKNTTQPRLWLEITLLGLL
CCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHH
PAAFGQTQTTRTATTPLNTQINLQTQPTATPPTSPPPPQDIPHPFGETPPATNGHGSGTP
HHHCCCCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSPVDTQVHQVPPKPEVPQVPAPVPEAKAIAKAPPSQDVIPPTVQPTEPPPLSPSPPATT
CCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPTISALEREELWQGIVRQLPLLSQSLFRDHGKLLQLTDHSALIGIKSANLLKIAKNKTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCEEEECCCCCE
QLEAAFEKICGNPLKVTLQVGHGLENGQGGTSVTPILSTPAPAPTVISPAQNPIEMPPPP
EHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEECEEECCCCCCCCEECCCCCCCCCCCCC
VAETPQPMAPPPLGSPTKPAPDPKPPEPTPTAHRKADLGEITPPAPAVPPLVESASASEP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCC
TATAEIPETTDDIQAIAQQFAELFDGEVIELTHFVPPEETDVQVVLPPEPEKPPPPVPEP
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCC
PTIPVVQGRPPVPVAPDDEIPF
CCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]