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The map label for this gene is acnB [H]

Identifier: 170078290

GI number: 170078290

Start: 1766376

End: 1768982

Strand: Direct

Name: acnB [H]

Synonym: SYNPCC7002_A1683

Alternate gene names: 170078290

Gene position: 1766376-1768982 (Clockwise)

Preceding gene: 170078289

Following gene: 170078291

Centisome position: 58.72

GC content: 53.09

Gene sequence:

>2607_bases
ATGCTAGAAGCCTACCGCAAACACGCCGCCGAACGCGCCCAATTGGGAATTCCCCCTTTACCGCTAACCGCAGAACAAAC
CTCTGAACTCTGCGATCGCCTCAAAAATCCCCCCGAAGCAGAACAAGCAGAACTGCTGAGTTTATTGCGCGATCGCGTGC
CTCCCGGTGTTGATGAAGCCGCCTATGTGAAAGCGGGTTTTTTAACCGGAATTGCCAAAAAAGAAATTACTTGTCCCCTG
ATCAGTCCCCAGGGTGCAGTGGAACTCCTGGGAACTATGGTGGGTGGCTATAACGTCCAATCCCTCGTCGAACTCCTCAA
ATCCCCCGACAGCAATATTGCCAGTGCCGCCGCCACTGCCCTGAGCAAAACTCTGTTGGTTTTCGATGCCTTTAACGATG
TCCTCGAACTCTCTGATACCAACCCCTACGCCAAACAAGTGATCGATGCTTGGGCAGAAGCCGCTTGGTTTATCGGTAAG
CCCAAAGTTCCCGAGGCGATCGCCGTTACTGTCTTTAAGGTTCCCGGCGAAACCAATACCGATGACCTTTCTCCCGCGCC
CCACGCCACAACTCGCCCCGACATTCCCCTCCATGCCCTCGCAATGCTGGAATCAAAAATGCCAGAGGGGTTAGAAACTA
TTGCCGAACTGAAGCAAAAAGGTCATCCCGTTGCCTATGTCGGTGATGTGGTCGGTACCGGTTCCTCTCGGAAATCAGCG
ATCAACTCCGTACTATGGCACCTCGGCCACGACATTCCCTTTGTCCCCAACAAAAAAGCAGGCGGTTATATTCTCGGCGG
TAAAATTGCCCCGATTTTCTTCAATACCGCTGAAGACTCCGGTGCACTGCCCATTGAGTGTGATGTCAGTAAGCTTAATA
CGGGCGATGTGATCACCATTCATCCCTACGCAGGCAAAATTACTAACGAAGCGGGTGAAACAATCTCTACCTTTGAACTA
AAGCCTGAAACGATCCTCGACGAAGTGCAAGCGGGTGGCCGAATTCCTTTGCTGATTGGCCGGGCACTCACCGACAAAAC
CCGTGAAGCCCTCGGACTCGAACCGACGACGGTGTTTGTGCGTCCCTCCCTGCCAGAAGATACCCACAAAGGGTTTACCT
TGGCACAAAAAATGGTGGGTAAAGCGTGCGGTTTAGAAGGGGTTCGTCCTGGGACATCCTGCGAGCCGATCATGACCACC
GTGGGTTCCCAAGACACCACTGGCCCGATGACTCGCGATGAGCTAAAAGAGCTGGCTTGTCTCGGTTTCAATGCGGACTT
GACCCTACAAACTTTCTGTCACACTGCCGCCTATCCGAAGCCAGTTGATGTCGTTACCCACAAACAACTGCCCGACTTCT
TTGCGACCCGTGGCGGTGTTGCCCTCAAACCCGGTGATGGCATTATCCACTCGTGGCTGAACCGGATGTTATTGCCCGAT
ACCGTGGGAACTGGTGGTGACTCCCATACCCGTTTCCCCTTGGGGATTTCTTTCCCGGCGGGTTCTGGTTTGGTGGCCTT
TGCAGCGGCCCTCGGTGTCATGCCCCTTGATATGCCGGAATCTGTCCTCGTGAAATTTACGGGCGAACTGCAACCCGGTG
TCACCCTCCGCGATATTGTCAATGCGATTCCCTGGGTGGCGATGCAACAGGGTAAATTGACCGTCGGCAAAGAGAACAAG
GTTAACGTCTTTAACGGTCGGATCATGGAAATGGAAGGTCTGCCGGATCTCAAGGTAGAGCAAGCCTTTGAATTGACCGA
TGCTACTGCCGAGCGTTCCTGTTCTGGTTCGACGATTAAACTCAGCGAAGAAACCGTGGCGGAATATCTGCGGTCTAATG
TCGTGCTGATGAAGAACATGATTGCCCGTGGTTACTCCGATGCGCGTACCCTACTGCGTCGGATTGCGAAGATGGAGGAA
TGGCTCGCGAATCCTTCTCTGATGTCGGCGGATCCTGATGCGGAATATGCGGATGTGATCGAGGTGAACCTGAATGAGAT
TAAGGAACCCATCGTTGCGGCTCCGAACGATCCTGACAATGTCAAACTGATGTCTGAATGTGCAGGGGACAAAGTTGATG
AGGTGTTCATCGGTTCCTGCATGACGAATATTGGTCACTACCGCGCAGCGGCGAAAATCCTGGAAGGGGCGGGTGTTGTC
AAAGGTCGTCTCTGGATTTGTCCACCCACGCGCATGGATGAAAAGCAACTCCGGGATGAAGGGGTTTACGGTGTCTTCGC
GGCGGCAGGAGCGCGGACGGAAATGCCCGGCTGTTCTCTTTGTATGGGGAACCAAGCCCGCGTTGAAGATAATGCAACAG
TTTTCTCTACTTCGACCCGGAACTTCAATAACCGGATGGGCAAGGGGGCGCAAGTTTACCTTGGTTCGGCGGAGTTAGCA
GCGGTTTGTGCGCTCCTCGGCAAGATTCCCACTGTGGAAGAATATCAGGCGATCGTCTCTGAGAAGATTGATCCGTTTAA
GGGTGATCTATACCGTTATCTCAATTTCAATGAGATTGATGGCTTTGAGGATGAGGGTCGCGTGATTGCCCTTGAGGATA
TGCCGAAGATCGAAGATCTCCTCGGTATGCCTGTAGGCGCGAAGTAA

Upstream 100 bases:

>100_bases
TCTATGGACAATCCAAGACTGAGATTGTTCACCCATAGCGTCATTACAGCGGGCATTACAATAGAGTATCTAAAACGTTA
GATAACCGATAGATCTCCCT

Downstream 100 bases:

>100_bases
AAATATAGGAATCTGATTTTATAATTAAGGTGAATCATCATTGATTCACCTTTTATTAGCCTATAATTTAATTATCATTT
TTATCCTAAGAAAGAAAAAT

Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase

Products: NA

Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]

Number of amino acids: Translated: 868; Mature: 868

Protein sequence:

>868_residues
MLEAYRKHAAERAQLGIPPLPLTAEQTSELCDRLKNPPEAEQAELLSLLRDRVPPGVDEAAYVKAGFLTGIAKKEITCPL
ISPQGAVELLGTMVGGYNVQSLVELLKSPDSNIASAAATALSKTLLVFDAFNDVLELSDTNPYAKQVIDAWAEAAWFIGK
PKVPEAIAVTVFKVPGETNTDDLSPAPHATTRPDIPLHALAMLESKMPEGLETIAELKQKGHPVAYVGDVVGTGSSRKSA
INSVLWHLGHDIPFVPNKKAGGYILGGKIAPIFFNTAEDSGALPIECDVSKLNTGDVITIHPYAGKITNEAGETISTFEL
KPETILDEVQAGGRIPLLIGRALTDKTREALGLEPTTVFVRPSLPEDTHKGFTLAQKMVGKACGLEGVRPGTSCEPIMTT
VGSQDTTGPMTRDELKELACLGFNADLTLQTFCHTAAYPKPVDVVTHKQLPDFFATRGGVALKPGDGIIHSWLNRMLLPD
TVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESVLVKFTGELQPGVTLRDIVNAIPWVAMQQGKLTVGKENK
VNVFNGRIMEMEGLPDLKVEQAFELTDATAERSCSGSTIKLSEETVAEYLRSNVVLMKNMIARGYSDARTLLRRIAKMEE
WLANPSLMSADPDAEYADVIEVNLNEIKEPIVAAPNDPDNVKLMSECAGDKVDEVFIGSCMTNIGHYRAAAKILEGAGVV
KGRLWICPPTRMDEKQLRDEGVYGVFAAAGARTEMPGCSLCMGNQARVEDNATVFSTSTRNFNNRMGKGAQVYLGSAELA
AVCALLGKIPTVEEYQAIVSEKIDPFKGDLYRYLNFNEIDGFEDEGRVIALEDMPKIEDLLGMPVGAK

Sequences:

>Translated_868_residues
MLEAYRKHAAERAQLGIPPLPLTAEQTSELCDRLKNPPEAEQAELLSLLRDRVPPGVDEAAYVKAGFLTGIAKKEITCPL
ISPQGAVELLGTMVGGYNVQSLVELLKSPDSNIASAAATALSKTLLVFDAFNDVLELSDTNPYAKQVIDAWAEAAWFIGK
PKVPEAIAVTVFKVPGETNTDDLSPAPHATTRPDIPLHALAMLESKMPEGLETIAELKQKGHPVAYVGDVVGTGSSRKSA
INSVLWHLGHDIPFVPNKKAGGYILGGKIAPIFFNTAEDSGALPIECDVSKLNTGDVITIHPYAGKITNEAGETISTFEL
KPETILDEVQAGGRIPLLIGRALTDKTREALGLEPTTVFVRPSLPEDTHKGFTLAQKMVGKACGLEGVRPGTSCEPIMTT
VGSQDTTGPMTRDELKELACLGFNADLTLQTFCHTAAYPKPVDVVTHKQLPDFFATRGGVALKPGDGIIHSWLNRMLLPD
TVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESVLVKFTGELQPGVTLRDIVNAIPWVAMQQGKLTVGKENK
VNVFNGRIMEMEGLPDLKVEQAFELTDATAERSCSGSTIKLSEETVAEYLRSNVVLMKNMIARGYSDARTLLRRIAKMEE
WLANPSLMSADPDAEYADVIEVNLNEIKEPIVAAPNDPDNVKLMSECAGDKVDEVFIGSCMTNIGHYRAAAKILEGAGVV
KGRLWICPPTRMDEKQLRDEGVYGVFAAAGARTEMPGCSLCMGNQARVEDNATVFSTSTRNFNNRMGKGAQVYLGSAELA
AVCALLGKIPTVEEYQAIVSEKIDPFKGDLYRYLNFNEIDGFEDEGRVIALEDMPKIEDLLGMPVGAK
>Mature_868_residues
MLEAYRKHAAERAQLGIPPLPLTAEQTSELCDRLKNPPEAEQAELLSLLRDRVPPGVDEAAYVKAGFLTGIAKKEITCPL
ISPQGAVELLGTMVGGYNVQSLVELLKSPDSNIASAAATALSKTLLVFDAFNDVLELSDTNPYAKQVIDAWAEAAWFIGK
PKVPEAIAVTVFKVPGETNTDDLSPAPHATTRPDIPLHALAMLESKMPEGLETIAELKQKGHPVAYVGDVVGTGSSRKSA
INSVLWHLGHDIPFVPNKKAGGYILGGKIAPIFFNTAEDSGALPIECDVSKLNTGDVITIHPYAGKITNEAGETISTFEL
KPETILDEVQAGGRIPLLIGRALTDKTREALGLEPTTVFVRPSLPEDTHKGFTLAQKMVGKACGLEGVRPGTSCEPIMTT
VGSQDTTGPMTRDELKELACLGFNADLTLQTFCHTAAYPKPVDVVTHKQLPDFFATRGGVALKPGDGIIHSWLNRMLLPD
TVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESVLVKFTGELQPGVTLRDIVNAIPWVAMQQGKLTVGKENK
VNVFNGRIMEMEGLPDLKVEQAFELTDATAERSCSGSTIKLSEETVAEYLRSNVVLMKNMIARGYSDARTLLRRIAKMEE
WLANPSLMSADPDAEYADVIEVNLNEIKEPIVAAPNDPDNVKLMSECAGDKVDEVFIGSCMTNIGHYRAAAKILEGAGVV
KGRLWICPPTRMDEKQLRDEGVYGVFAAAGARTEMPGCSLCMGNQARVEDNATVFSTSTRNFNNRMGKGAQVYLGSAELA
AVCALLGKIPTVEEYQAIVSEKIDPFKGDLYRYLNFNEIDGFEDEGRVIALEDMPKIEDLLGMPVGAK

Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]

COG id: COG1049

COG function: function code C; Aconitase B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aconitase/IPM isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367097, Length=859, Percent_Identity=65.6577415599534, Blast_Score=1108, Evalue=0.0,
Organism=Escherichia coli, GI1786259, Length=368, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323335, Length=401, Percent_Identity=25.6857855361596, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321429, Length=369, Percent_Identity=24.390243902439, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015931
- InterPro:   IPR015937
- InterPro:   IPR001030
- InterPro:   IPR015928
- InterPro:   IPR018136
- InterPro:   IPR004406
- InterPro:   IPR015930
- InterPro:   IPR015933
- InterPro:   IPR015929 [H]

Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]

EC number: =4.2.1.3; =4.2.1.99 [H]

Molecular weight: Translated: 93358; Mature: 93358

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00450 ACONITASE_1 ; PS01244 ACONITASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEAYRKHAAERAQLGIPPLPLTAEQTSELCDRLKNPPEAEQAELLSLLRDRVPPGVDEA
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCH
AYVKAGFLTGIAKKEITCPLISPQGAVELLGTMVGGYNVQSLVELLKSPDSNIASAAATA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
LSKTLLVFDAFNDVLELSDTNPYAKQVIDAWAEAAWFIGKPKVPEAIAVTVFKVPGETNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCCEEEEEEEECCCCCCC
DDLSPAPHATTRPDIPLHALAMLESKMPEGLETIAELKQKGHPVAYVGDVVGTGSSRKSA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH
INSVLWHLGHDIPFVPNKKAGGYILGGKIAPIFFNTAEDSGALPIECDVSKLNTGDVITI
HHHHHHHHCCCCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCEEEECCCCCCCCCEEEE
HPYAGKITNEAGETISTFELKPETILDEVQAGGRIPLLIGRALTDKTREALGLEPTTVFV
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCEEEEE
RPSLPEDTHKGFTLAQKMVGKACGLEGVRPGTSCEPIMTTVGSQDTTGPMTRDELKELAC
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHH
LGFNADLTLQTFCHTAAYPKPVDVVTHKQLPDFFATRGGVALKPGDGIIHSWLNRMLLPD
HCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCHHHHCCCCEEECCCCCHHHHHHHHHCCCC
TVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESVLVKFTGELQPGVTLRDIV
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCHHHHH
NAIPWVAMQQGKLTVGKENKVNVFNGRIMEMEGLPDLKVEQAFELTDATAERSCSGSTIK
HHHCCCEEECCCEEECCCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEE
LSEETVAEYLRSNVVLMKNMIARGYSDARTLLRRIAKMEEWLANPSLMSADPDAEYADVI
ECHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEE
EVNLNEIKEPIVAAPNDPDNVKLMSECAGDKVDEVFIGSCMTNIGHYRAAAKILEGAGVV
EECHHHHCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
KGRLWICPPTRMDEKQLRDEGVYGVFAAAGARTEMPGCSLCMGNQARVEDNATVFSTSTR
ECEEEECCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCEECCCCEEEEECCC
NFNNRMGKGAQVYLGSAELAAVCALLGKIPTVEEYQAIVSEKIDPFKGDLYRYLNFNEID
CHHHHCCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
GFEDEGRVIALEDMPKIEDLLGMPVGAK
CCCCCCCEEEECCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MLEAYRKHAAERAQLGIPPLPLTAEQTSELCDRLKNPPEAEQAELLSLLRDRVPPGVDEA
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCH
AYVKAGFLTGIAKKEITCPLISPQGAVELLGTMVGGYNVQSLVELLKSPDSNIASAAATA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
LSKTLLVFDAFNDVLELSDTNPYAKQVIDAWAEAAWFIGKPKVPEAIAVTVFKVPGETNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCCEEEEEEEECCCCCCC
DDLSPAPHATTRPDIPLHALAMLESKMPEGLETIAELKQKGHPVAYVGDVVGTGSSRKSA
CCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH
INSVLWHLGHDIPFVPNKKAGGYILGGKIAPIFFNTAEDSGALPIECDVSKLNTGDVITI
HHHHHHHHCCCCCCCCCCCCCCEEECCEEEEEEEECCCCCCCCEEEECCCCCCCCCEEEE
HPYAGKITNEAGETISTFELKPETILDEVQAGGRIPLLIGRALTDKTREALGLEPTTVFV
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCEEEEE
RPSLPEDTHKGFTLAQKMVGKACGLEGVRPGTSCEPIMTTVGSQDTTGPMTRDELKELAC
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHH
LGFNADLTLQTFCHTAAYPKPVDVVTHKQLPDFFATRGGVALKPGDGIIHSWLNRMLLPD
HCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCHHHHCCCCEEECCCCCHHHHHHHHHCCCC
TVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESVLVKFTGELQPGVTLRDIV
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCHHHHH
NAIPWVAMQQGKLTVGKENKVNVFNGRIMEMEGLPDLKVEQAFELTDATAERSCSGSTIK
HHHCCCEEECCCEEECCCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEE
LSEETVAEYLRSNVVLMKNMIARGYSDARTLLRRIAKMEEWLANPSLMSADPDAEYADVI
ECHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEE
EVNLNEIKEPIVAAPNDPDNVKLMSECAGDKVDEVFIGSCMTNIGHYRAAAKILEGAGVV
EECHHHHCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
KGRLWICPPTRMDEKQLRDEGVYGVFAAAGARTEMPGCSLCMGNQARVEDNATVFSTSTR
ECEEEECCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCEECCCCEEEEECCC
NFNNRMGKGAQVYLGSAELAAVCALLGKIPTVEEYQAIVSEKIDPFKGDLYRYLNFNEID
CHHHHCCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
GFEDEGRVIALEDMPKIEDLLGMPVGAK
CCCCCCCEEEECCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]