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The map label for this gene is trx [H]

Identifier: 170078222

GI number: 170078222

Start: 1693998

End: 1694321

Strand: Reverse

Name: trx [H]

Synonym: SYNPCC7002_A1614

Alternate gene names: 170078222

Gene position: 1694321-1693998 (Counterclockwise)

Preceding gene: 170078224

Following gene: 170078214

Centisome position: 56.33

GC content: 49.69

Gene sequence:

>324_bases
ATGTCAAAAACTGCCGCAGTCACAGACGCAACCTTTCAAGAAGAAGTCCTCGAAAGTGACGTCCCTGTACTCGTCGACTT
CTGGGCTCCTTGGTGTGGTCCCTGTCGTATGGTTGCTCCCGTCGTGGAGGAGATCGCCGAACAATACCAAGATCAAATCA
AGGTGTTTAAGCTCAATACTGACGAAAACCCTGGTGTCGCCAGCGAATATGGTATTCGGAGCATCCCGACCTTGATGATT
TTCAAAGGGGGCAAAAAGGTCAGCATGGTAGTCGGTGCTGTGCCCAAAACAACCCTCGCTGCTGCGATTGATAAAGAACT
TTAA

Upstream 100 bases:

>100_bases
TTCTATCATTTTGCCTAAAGTTCCAGATGGGTCGGAGCCTTTATGCTAGAATCCCTAGGTATCCTTAGAAAAATCTTGTA
TAAATTAGGAATTTAGAGGC

Downstream 100 bases:

>100_bases
AAAAATTCTCTTAATAACTTCAACGCACTACGAGCCACCAACGGCATCATTTAACATCCGGCTTTTGCACTCAGCCCTAG
CGTATTCCTAGGGTTTTTTA

Product: thioredoxin

Products: NA

Alternate protein names: Trx-1; Thioredoxin-M [H]

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSKTAAVTDATFQEEVLESDVPVLVDFWAPWCGPCRMVAPVVEEIAEQYQDQIKVFKLNTDENPGVASEYGIRSIPTLMI
FKGGKKVSMVVGAVPKTTLAAAIDKEL

Sequences:

>Translated_107_residues
MSKTAAVTDATFQEEVLESDVPVLVDFWAPWCGPCRMVAPVVEEIAEQYQDQIKVFKLNTDENPGVASEYGIRSIPTLMI
FKGGKKVSMVVGAVPKTTLAAAIDKEL
>Mature_106_residues
SKTAAVTDATFQEEVLESDVPVLVDFWAPWCGPCRMVAPVVEEIAEQYQDQIKVFKLNTDENPGVASEYGIRSIPTLMIF
KGGKKVSMVVGAVPKTTLAAAIDKEL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=94, Percent_Identity=34.0425531914894, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI50592994, Length=105, Percent_Identity=39.0476190476191, Blast_Score=68, Evalue=2e-12,
Organism=Homo sapiens, GI5031973, Length=80, Percent_Identity=35, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI224493972, Length=91, Percent_Identity=32.967032967033, Blast_Score=64, Evalue=2e-11,
Organism=Homo sapiens, GI42794771, Length=86, Percent_Identity=33.7209302325581, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI87082331, Length=106, Percent_Identity=50, Blast_Score=123, Evalue=3e-30,
Organism=Escherichia coli, GI1788936, Length=94, Percent_Identity=45.7446808510638, Blast_Score=107, Evalue=2e-25,
Organism=Escherichia coli, GI87081747, Length=94, Percent_Identity=34.0425531914894, Blast_Score=69, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI212646193, Length=88, Percent_Identity=40.9090909090909, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17509965, Length=72, Percent_Identity=43.0555555555556, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71998175, Length=71, Percent_Identity=40.8450704225352, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115532378, Length=72, Percent_Identity=37.5, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17510299, Length=74, Percent_Identity=40.5405405405405, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532380, Length=72, Percent_Identity=37.5, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507705, Length=71, Percent_Identity=36.6197183098592, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17544108, Length=72, Percent_Identity=37.5, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17556044, Length=78, Percent_Identity=35.8974358974359, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17554386, Length=82, Percent_Identity=37.8048780487805, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17549970, Length=80, Percent_Identity=35, Blast_Score=61, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6321648, Length=84, Percent_Identity=47.6190476190476, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323072, Length=93, Percent_Identity=45.1612903225806, Blast_Score=86, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319925, Length=89, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639826, Length=80, Percent_Identity=43.75, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17648013, Length=74, Percent_Identity=43.2432432432432, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24583090, Length=74, Percent_Identity=43.2432432432432, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573567, Length=85, Percent_Identity=35.2941176470588, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24664269, Length=82, Percent_Identity=40.2439024390244, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19921434, Length=80, Percent_Identity=35, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358065, Length=81, Percent_Identity=37.037037037037, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11661; Mature: 11529

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAAVTDATFQEEVLESDVPVLVDFWAPWCGPCRMVAPVVEEIAEQYQDQIKVFKLNT
CCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECC
DENPGVASEYGIRSIPTLMIFKGGKKVSMVVGAVPKTTLAAAIDKEL
CCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SKTAAVTDATFQEEVLESDVPVLVDFWAPWCGPCRMVAPVVEEIAEQYQDQIKVFKLNT
CCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEECC
DENPGVASEYGIRSIPTLMIFKGGKKVSMVVGAVPKTTLAAAIDKEL
CCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2492995 [H]