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The map label for this gene is ilvA [H]

Identifier: 170078224

GI number: 170078224

Start: 1696019

End: 1697530

Strand: Reverse

Name: ilvA [H]

Synonym: SYNPCC7002_A1616

Alternate gene names: 170078224

Gene position: 1697530-1696019 (Counterclockwise)

Preceding gene: 170078225

Following gene: 170078222

Centisome position: 56.43

GC content: 53.04

Gene sequence:

>1512_bases
ATGCATTGCGATTATTTGATCCAAATTTTAAATGCCCGCGTTTACGACGTAGCCCAAGAAACTCCCCTCGAAGTGGCCCC
CAATCTTTCGCGCCGCCTGCACAACCATGTGCTATTGAAGCGGGAGGATATGCAGTCGGTCTTTTCTTTTAAGCTGCGGG
GCGCGTACAACAAGATGGCGCACCTAACCCCAGAGCGATTGCAATGTGGCGTGATCGCTGCCTCCGCCGGAAACCATGCC
CAGGGGGTGGCCCTTGCCGCGACAAAGTTGGGCACGAGGGCAGTGATTGTAATGCCTGTGGTGACGCCCCAGGTCAAGAT
CAATGCCGTTAAAGCCAGGGGTGGCGAGGTGATCCTGCATGGAAATGCCTATGATGATGCCTACGCCCACGCCCGCAAAC
TCTCGGAGGAACAGGGCTTAACGCTCATTCATCCCTTTGATGATCCCTATGTCATCGCTGGCCAGGGCACCATCGGCATG
GAGATTTTACGCCAGTGCCAACAGCCCATCCACGCGATTTTTGTGGCGATTGGCGGCGGCGGATTAATTGCAGGCATTGC
GGCCTATGTGAAGCGGGTGCGGCCGGAGATCAAAATTATTGGCGTCGAACCTGTGGATGCCGATGCTATGAAACAATCCC
TTGCAACAGGGGAACGGGTGCAGTTATCCCAAGTGGGGTTGTTTGCCGATGGGGTGGCGGTGCGCTATGTCGGGGAAGAA
ACATTTCGCCTGTGCCAGGAATATGTCGATGAAATTATTCTGGTATCCACCGATGATACCTGTGCAGCCATTAAAGATGT
ATTTGAGGACACCCGCTCTATTTTGGAGCCGGCTGGGGCATTGGCGATCGCCGGGATGAAAGCCTATGTGGAGCGGGAAG
GCATTCAGGACGAAACCTTAGTAGCCGTTGCCTGTGGGGCCAATATGAACTTTGATCGCCTGCGGTTTGTGGCCGAGCGA
GCCGAATTAGGGGAAGGGCGAGAAGCAATTTTTGCCGTGACGATCCCGGAGCAACCGGGCAGTTTACGAAAGTTTTGCCG
TTGCATGGGCGATCGCAATTTAACGGAATTCAACTATCGCATTGCCGATGAACAGGAAGCCCATATTTTTGTGGGGGTAC
AAATTGCTGACCGCAGTGAAATTAAGACCCTCGCCGAAACCTTCGAAGCGAATGGCTTTAAAACCCTCAATCTCACCGAT
GACGAACTGACGAAATTACACCTGCGTCACATGGTCGGTGGCCGCAGTCCCAAGGCAACCCATGAGTTGTTCTATCGCTT
TGAGTTTCCTGAATATCCAGGGGCGTTGATGAAATTTGTCGATACCATGAGCCCCCATTGGAATATCAGTGGGTTCCACT
ATCGCAATAATGGTGCTGATTATGGACGGATTGCGATCGCCGTCCAGGTGCCCCCGGCAGAAATGGACGATTGGCAAACG
TTCCTCGACCAACTCGGTTATCGTTACTGGGACGAAAATCAAAATCCCGCCTACAAGCTCTTTTTGGGCTAA

Upstream 100 bases:

>100_bases
AACCTTTTCGTTGAACTAGGCTTTCGTGGATTGACGGGATGGGGTTACAGTAAAATCCTCACACTTTATCTGTCCTAAAA
TTCCCGTTGGCGATCGCCCT

Downstream 100 bases:

>100_bases
GGTTTTGTCCTACTCCCAAAGCACGGCGGCCCGCTCTTGAACCACACGTTGGTAAACCTGCTCCGTGGCGATCGCCAATT
TTGCCCAATTAAAACGCCGG

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MHCDYLIQILNARVYDVAQETPLEVAPNLSRRLHNHVLLKREDMQSVFSFKLRGAYNKMAHLTPERLQCGVIAASAGNHA
QGVALAATKLGTRAVIVMPVVTPQVKINAVKARGGEVILHGNAYDDAYAHARKLSEEQGLTLIHPFDDPYVIAGQGTIGM
EILRQCQQPIHAIFVAIGGGGLIAGIAAYVKRVRPEIKIIGVEPVDADAMKQSLATGERVQLSQVGLFADGVAVRYVGEE
TFRLCQEYVDEIILVSTDDTCAAIKDVFEDTRSILEPAGALAIAGMKAYVEREGIQDETLVAVACGANMNFDRLRFVAER
AELGEGREAIFAVTIPEQPGSLRKFCRCMGDRNLTEFNYRIADEQEAHIFVGVQIADRSEIKTLAETFEANGFKTLNLTD
DELTKLHLRHMVGGRSPKATHELFYRFEFPEYPGALMKFVDTMSPHWNISGFHYRNNGADYGRIAIAVQVPPAEMDDWQT
FLDQLGYRYWDENQNPAYKLFLG

Sequences:

>Translated_503_residues
MHCDYLIQILNARVYDVAQETPLEVAPNLSRRLHNHVLLKREDMQSVFSFKLRGAYNKMAHLTPERLQCGVIAASAGNHA
QGVALAATKLGTRAVIVMPVVTPQVKINAVKARGGEVILHGNAYDDAYAHARKLSEEQGLTLIHPFDDPYVIAGQGTIGM
EILRQCQQPIHAIFVAIGGGGLIAGIAAYVKRVRPEIKIIGVEPVDADAMKQSLATGERVQLSQVGLFADGVAVRYVGEE
TFRLCQEYVDEIILVSTDDTCAAIKDVFEDTRSILEPAGALAIAGMKAYVEREGIQDETLVAVACGANMNFDRLRFVAER
AELGEGREAIFAVTIPEQPGSLRKFCRCMGDRNLTEFNYRIADEQEAHIFVGVQIADRSEIKTLAETFEANGFKTLNLTD
DELTKLHLRHMVGGRSPKATHELFYRFEFPEYPGALMKFVDTMSPHWNISGFHYRNNGADYGRIAIAVQVPPAEMDDWQT
FLDQLGYRYWDENQNPAYKLFLG
>Mature_503_residues
MHCDYLIQILNARVYDVAQETPLEVAPNLSRRLHNHVLLKREDMQSVFSFKLRGAYNKMAHLTPERLQCGVIAASAGNHA
QGVALAATKLGTRAVIVMPVVTPQVKINAVKARGGEVILHGNAYDDAYAHARKLSEEQGLTLIHPFDDPYVIAGQGTIGM
EILRQCQQPIHAIFVAIGGGGLIAGIAAYVKRVRPEIKIIGVEPVDADAMKQSLATGERVQLSQVGLFADGVAVRYVGEE
TFRLCQEYVDEIILVSTDDTCAAIKDVFEDTRSILEPAGALAIAGMKAYVEREGIQDETLVAVACGANMNFDRLRFVAER
AELGEGREAIFAVTIPEQPGSLRKFCRCMGDRNLTEFNYRIADEQEAHIFVGVQIADRSEIKTLAETFEANGFKTLNLTD
DELTKLHLRHMVGGRSPKATHELFYRFEFPEYPGALMKFVDTMSPHWNISGFHYRNNGADYGRIAIAVQVPPAEMDDWQT
FLDQLGYRYWDENQNPAYKLFLG

Specific function: Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=315, Percent_Identity=30.7936507936508, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI33469958, Length=315, Percent_Identity=29.2063492063492, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI19923959, Length=319, Percent_Identity=28.8401253918495, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1790207, Length=500, Percent_Identity=52.4, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1789505, Length=307, Percent_Identity=38.4364820846906, Blast_Score=172, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71991565, Length=331, Percent_Identity=31.1178247734139, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17537387, Length=323, Percent_Identity=33.7461300309598, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17508781, Length=307, Percent_Identity=28.6644951140065, Blast_Score=127, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320930, Length=514, Percent_Identity=51.3618677042802, Blast_Score=494, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6322631, Length=301, Percent_Identity=35.5481727574751, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319788, Length=299, Percent_Identity=23.4113712374582, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322024, Length=187, Percent_Identity=25.668449197861, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21355833, Length=308, Percent_Identity=33.1168831168831, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645328, Length=249, Percent_Identity=30.9236947791165, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005787
- InterPro:   IPR001721 [H]

Pfam domain/function: PF00291 PALP; PF00585 Thr_dehydrat_C [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 55877; Mature: 55877

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCDYLIQILNARVYDVAQETPLEVAPNLSRRLHNHVLLKREDMQSVFSFKLRGAYNKMA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEHHHHHHHHHHHHHCHHHHHH
HLTPERLQCGVIAASAGNHAQGVALAATKLGTRAVIVMPVVTPQVKINAVKARGGEVILH
CCCHHHHEEEEEEECCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEEEECCCEEEEE
GNAYDDAYAHARKLSEEQGLTLIHPFDDPYVIAGQGTIGMEILRQCQQPIHAIFVAIGGG
CCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHEEEEEEECCC
GLIAGIAAYVKRVRPEIKIIGVEPVDADAMKQSLATGERVQLSQVGLFADGVAVRYVGEE
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEHHHCCEEECCEEEEEECHH
TFRLCQEYVDEIILVSTDDTCAAIKDVFEDTRSILEPAGALAIAGMKAYVEREGIQDETL
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
VAVACGANMNFDRLRFVAERAELGEGREAIFAVTIPEQPGSLRKFCRCMGDRNLTEFNYR
EEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEE
IADEQEAHIFVGVQIADRSEIKTLAETFEANGFKTLNLTDDELTKLHLRHMVGGRSPKAT
ECCCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCH
HELFYRFEFPEYPGALMKFVDTMSPHWNISGFHYRNNGADYGRIAIAVQVPPAEMDDWQT
HEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHH
FLDQLGYRYWDENQNPAYKLFLG
HHHHCCCEECCCCCCCCEEEEEC
>Mature Secondary Structure
MHCDYLIQILNARVYDVAQETPLEVAPNLSRRLHNHVLLKREDMQSVFSFKLRGAYNKMA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEHHHHHHHHHHHHHCHHHHHH
HLTPERLQCGVIAASAGNHAQGVALAATKLGTRAVIVMPVVTPQVKINAVKARGGEVILH
CCCHHHHEEEEEEECCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEEEECCCEEEEE
GNAYDDAYAHARKLSEEQGLTLIHPFDDPYVIAGQGTIGMEILRQCQQPIHAIFVAIGGG
CCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHEEEEEEECCC
GLIAGIAAYVKRVRPEIKIIGVEPVDADAMKQSLATGERVQLSQVGLFADGVAVRYVGEE
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEHHHCCEEECCEEEEEECHH
TFRLCQEYVDEIILVSTDDTCAAIKDVFEDTRSILEPAGALAIAGMKAYVEREGIQDETL
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
VAVACGANMNFDRLRFVAERAELGEGREAIFAVTIPEQPGSLRKFCRCMGDRNLTEFNYR
EEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEE
IADEQEAHIFVGVQIADRSEIKTLAETFEANGFKTLNLTDDELTKLHLRHMVGGRSPKAT
ECCCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCH
HELFYRFEFPEYPGALMKFVDTMSPHWNISGFHYRNNGADYGRIAIAVQVPPAEMDDWQT
HEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHH
FLDQLGYRYWDENQNPAYKLFLG
HHHHCCCEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA