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The map label for this gene is tyrS [H]

Identifier: 170078217

GI number: 170078217

Start: 1689429

End: 1690604

Strand: Direct

Name: tyrS [H]

Synonym: SYNPCC7002_A1609

Alternate gene names: 170078217

Gene position: 1689429-1690604 (Clockwise)

Preceding gene: 170078216

Following gene: 170078218

Centisome position: 56.16

GC content: 51.02

Gene sequence:

>1176_bases
ATGTCTGCGAATCTTGAGTGGCTAACCCGTGGCACCAGCGAAATTTTTCCGGATAATCCTGAAGAAAATTTAGCCCAGGT
TCTCCAGACAGGCGATCGCCCCTTGAGGGTCAAATTAGGCGTTGATCCGACGGGTTCAGATCTCCACCTCGGCCATAGTA
TTCCGTTCCGTAAACTGCGTGCATTCCAAGACGCTGGCCACACCGCAGTGGTGATTATTGGTGACTTTACCGCCCAGATT
GGCGACCCCACCGGCAAATCAGAAGTGCGCAAACAGCTCAGTGCCGCCGACGTGCAACAAAATGCCGAAACTTACCTAGA
GCAACTGCGACCAATCCTCGATTTTGAGACCCCAGGCCGCCTCGAAATTCGCTATAACTCCGAATGGCTCAAGGATTTAG
ATTTAGCCAAGATCCAAGCACTGCTGGCGACAATGACGGTGCAGCAAATGCTGGCTAAAGAAGGCTTTGCCAAACGTTAC
CAAAGCGAAAACCCGATTTATATCCATGAATTTCTTTATCCCCTAATGCAGGGCTATGACTCGGTGGCCGTGGATGCAGA
TGTAGAACTTGGGGGCACTGACCAAAAATTTAATATTGCCGTGGGGCGGGATCTGCAAAGACACTTTGGGAAAAAGCCCC
AATTCGGCCTATTGCTGCCTATCTTGATCGGTACCGATGGCAAAGAAAAAATGTCCAAAAGTCTCAATAACTATGTGGGC
CTCAAGGACAATCACCACACCATGTACCAAAAGTTACAGAATACCCCCGATAGCTTGCTGAAGGACTATTTTGAACTGCT
CACTAAACAAGACCTGCAAACCTTGCCGACAAACCCCCGTGACCAGCAGAAACTCCTGGCCCGGGACATTGTTACTCAGT
TCCATGGGGCTGAAGCGGCGGTAGATGCGGAGAAAGCTGTACAGGATGTCGCCGCCGCCAATATTCCCGAATTTTCCCTG
GGCGCAGTGGAATTCCCCTCGCCTCTGTTTTATATTTTGGGGGCTTCTGGCCTGTGTTCCAGCGGTGGGGATGGTCGTCG
CCAAATTAAAGGAGGTGCAGTTCGCCTCGATGATGAGCGGATCACGGACATGAATCTCGCCTTTGAGAAGCCGGAGCAAT
TAGTAGATAAGGTGCTCCGGGTGGGGAAAAAGAAATTTGTCCGCCTCGTGCCCTAG

Upstream 100 bases:

>100_bases
GGCAGCTTATCGCTTGGCTGCATTCAATAATCTCAGCAGAATATGGCACAATAGGCAGGTTTAAATTTCCACAATTGAGT
TAACAAAATCCCCTGTGAAT

Downstream 100 bases:

>100_bases
GATTGGGACTCTGATTTTTGGGGATTTCGTGAACAGTTGTAACATTTCCGGTTGTTCTCAGAAAAAATTCTGCGATTAGG
GACGGACAACGCGATACCCT

Product: tyrosyl-tRNA synthetase

Products: NA

Alternate protein names: Tyrosine--tRNA ligase; TyrRS [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSANLEWLTRGTSEIFPDNPEENLAQVLQTGDRPLRVKLGVDPTGSDLHLGHSIPFRKLRAFQDAGHTAVVIIGDFTAQI
GDPTGKSEVRKQLSAADVQQNAETYLEQLRPILDFETPGRLEIRYNSEWLKDLDLAKIQALLATMTVQQMLAKEGFAKRY
QSENPIYIHEFLYPLMQGYDSVAVDADVELGGTDQKFNIAVGRDLQRHFGKKPQFGLLLPILIGTDGKEKMSKSLNNYVG
LKDNHHTMYQKLQNTPDSLLKDYFELLTKQDLQTLPTNPRDQQKLLARDIVTQFHGAEAAVDAEKAVQDVAAANIPEFSL
GAVEFPSPLFYILGASGLCSSGGDGRRQIKGGAVRLDDERITDMNLAFEKPEQLVDKVLRVGKKKFVRLVP

Sequences:

>Translated_391_residues
MSANLEWLTRGTSEIFPDNPEENLAQVLQTGDRPLRVKLGVDPTGSDLHLGHSIPFRKLRAFQDAGHTAVVIIGDFTAQI
GDPTGKSEVRKQLSAADVQQNAETYLEQLRPILDFETPGRLEIRYNSEWLKDLDLAKIQALLATMTVQQMLAKEGFAKRY
QSENPIYIHEFLYPLMQGYDSVAVDADVELGGTDQKFNIAVGRDLQRHFGKKPQFGLLLPILIGTDGKEKMSKSLNNYVG
LKDNHHTMYQKLQNTPDSLLKDYFELLTKQDLQTLPTNPRDQQKLLARDIVTQFHGAEAAVDAEKAVQDVAAANIPEFSL
GAVEFPSPLFYILGASGLCSSGGDGRRQIKGGAVRLDDERITDMNLAFEKPEQLVDKVLRVGKKKFVRLVP
>Mature_390_residues
SANLEWLTRGTSEIFPDNPEENLAQVLQTGDRPLRVKLGVDPTGSDLHLGHSIPFRKLRAFQDAGHTAVVIIGDFTAQIG
DPTGKSEVRKQLSAADVQQNAETYLEQLRPILDFETPGRLEIRYNSEWLKDLDLAKIQALLATMTVQQMLAKEGFAKRYQ
SENPIYIHEFLYPLMQGYDSVAVDADVELGGTDQKFNIAVGRDLQRHFGKKPQFGLLLPILIGTDGKEKMSKSLNNYVGL
KDNHHTMYQKLQNTPDSLLKDYFELLTKQDLQTLPTNPRDQQKLLARDIVTQFHGAEAAVDAEKAVQDVAAANIPEFSLG
AVEFPSPLFYILGASGLCSSGGDGRRQIKGGAVRLDDERITDMNLAFEKPEQLVDKVLRVGKKKFVRLVP

Specific function: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction:tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) [H]

COG id: COG0162

COG function: function code J; Tyrosyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI94681057, Length=402, Percent_Identity=25.8706467661692, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1787925, Length=405, Percent_Identity=28.8888888888889, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25145802, Length=307, Percent_Identity=26.7100977198697, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325160, Length=421, Percent_Identity=27.0783847980998, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI20130383, Length=422, Percent_Identity=26.303317535545, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: 892 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002942
- InterPro:   IPR002307 [H]

Pfam domain/function: PF01479 S4; PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.1 [H]

Molecular weight: Translated: 43587; Mature: 43456

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANLEWLTRGTSEIFPDNPEENLAQVLQTGDRPLRVKLGVDPTGSDLHLGHSIPFRKLR
CCCCCHHHHCCCHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCCCHHHHH
AFQDAGHTAVVIIGDFTAQIGDPTGKSEVRKQLSAADVQQNAETYLEQLRPILDFETPGR
HHHCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LEIRYNSEWLKDLDLAKIQALLATMTVQQMLAKEGFAKRYQSENPIYIHEFLYPLMQGYD
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCC
SVAVDADVELGGTDQKFNIAVGRDLQRHFGKKPQFGLLLPILIGTDGKEKMSKSLNNYVG
CEEEECCEEECCCCCEEEEEECCHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCC
LKDNHHTMYQKLQNTPDSLLKDYFELLTKQDLQTLPTNPRDQQKLLARDIVTQFHGAEAA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHH
VDAEKAVQDVAAANIPEFSLGAVEFPSPLFYILGASGLCSSGGDGRRQIKGGAVRLDDER
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHCCCCCEEECCCC
ITDMNLAFEKPEQLVDKVLRVGKKKFVRLVP
CCCCCCCCCCHHHHHHHHHHHCHHHHHCCCC
>Mature Secondary Structure 
SANLEWLTRGTSEIFPDNPEENLAQVLQTGDRPLRVKLGVDPTGSDLHLGHSIPFRKLR
CCCCHHHHCCCHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCCCHHHHH
AFQDAGHTAVVIIGDFTAQIGDPTGKSEVRKQLSAADVQQNAETYLEQLRPILDFETPGR
HHHCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LEIRYNSEWLKDLDLAKIQALLATMTVQQMLAKEGFAKRYQSENPIYIHEFLYPLMQGYD
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCC
SVAVDADVELGGTDQKFNIAVGRDLQRHFGKKPQFGLLLPILIGTDGKEKMSKSLNNYVG
CEEEECCEEECCCCCEEEEEECCHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCC
LKDNHHTMYQKLQNTPDSLLKDYFELLTKQDLQTLPTNPRDQQKLLARDIVTQFHGAEAA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHH
VDAEKAVQDVAAANIPEFSLGAVEFPSPLFYILGASGLCSSGGDGRRQIKGGAVRLDDER
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHCCCCCEEECCCC
ITDMNLAFEKPEQLVDKVLRVGKKKFVRLVP
CCCCCCCCCCHHHHHHHHHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]