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The map label for this gene is mprA [H]

Identifier: 170077989

GI number: 170077989

Start: 1435167

End: 1436354

Strand: Reverse

Name: mprA [H]

Synonym: SYNPCC7002_A1375

Alternate gene names: 170077989

Gene position: 1436354-1435167 (Counterclockwise)

Preceding gene: 170077991

Following gene: 170077988

Centisome position: 47.75

GC content: 48.82

Gene sequence:

>1188_bases
ATGCAAGGGAATCTCAATGAAATTGATCTCCGTAGTATTTTGCAGCTCCTTGAGCTGGGACAACGGACTGGGCAATTGTG
GATCGAAGCTCGACCATCGGGGGCCGTTGATGATTTGAGTTGGCAGTTTCCACAAGCGCCGCGTTTCCAACACTCACTGC
CTTTGTCCACCTGGTTAGTCTTTTTTGTGAATGGTCAAATTGTCTACGGGACTGATGACTATTCTCCCCAGATGTACCGT
TTGCAGGATTACCTTGTCCATTACCATCTCACCCACAAGCTAGGGGATCTTGATCGGGGGGCGATCGCCGAAACCACAAT
CCCTGAATATGCAGCCCTATGGCGACTTTTAGAAACCCAAACAATTACCGTTGATCAAGCGCGGCATATCCTCCAGGCAA
TGGTGCAAGAAACTTTGTTTGATCTCTTGAGTCTCCACCAGGGTCACTTTAATTTTCAGTTGGGGACTCCCTTTGGGCCA
CAGCTAAGCACCTATGCAGTGACTTCATTGCTGTTTGAGACGGTTAAAAAAGTCCAGAAATGGAAGCAACTCTATCCCCA
GATTCAATTTCCCCAACAACGTTTACTGCTGGCCCAACCCCAAAAACTTGCCGCCGCGCTACCGGCGATCGCCTACCAAA
AATTAGCCCAGTGGACTACCGGAGAAACGACTCTCCGCCAACTGGCCCGTTACCTCAATCGTGACCTCGTTGCCCTTGCG
AGGGCCTTGCTTCCCTATATCCAAAAGGGTTGGCTCCAAGTTCTAGATCCTCTCCCTCCCCAAAGTTTGTCACGTCCCAG
TGAAATGTCGTCTCACCAGACCAGGCGAATTCTTTGCATTGATGATGACTTCACCATCGGTAAGGCCGTAGAGCAAATCC
TCAGCACCCAGGGATATCAAGTGCACCTCGTCCAAAATCCCCTAGAGGCAATTCAAGCGGCCTTTGCTGAGGTGCCCCAT
TTAATTCTCTGTGATATTGCCATGCCCCACCTAGATGGCCATGAAATTTGTATGATGCTGCGTCACAGTAAGCGATTTCA
AAACGTTCCTATCATTATGCTGACTGGACAAGAGCAGTTTATTAACCGAATTCAGGCAGATTTTGCTGGGGCAACGGATT
ATTTAACAAAACCCTTCGGCCAGCAGGAGTTGTTAACCCTGCTAGAAAAATATCTCCCAAACCATTAG

Upstream 100 bases:

>100_bases
GATACTTGTCCACGACAGTGAATTGCGCCTGGGATTAGTTAAGCTTTAAATCCAAGGGCGATCGCCCTGTTCCCATGATC
CCAATGATCCCCAAAAAAGT

Downstream 100 bases:

>100_bases
CCAGTGCAGATCTCCCCAGGCGATCGCCCCCGGAGTGAAAAAACAAGCTATGATGGCGATGGCCTAACCCTTAGTCCCCA
TCGCACCCTTGCTGAATACC

Product: putative two component system response regulator

Products: NA

Alternate protein names: Mycobacterial persistence regulator A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQGNLNEIDLRSILQLLELGQRTGQLWIEARPSGAVDDLSWQFPQAPRFQHSLPLSTWLVFFVNGQIVYGTDDYSPQMYR
LQDYLVHYHLTHKLGDLDRGAIAETTIPEYAALWRLLETQTITVDQARHILQAMVQETLFDLLSLHQGHFNFQLGTPFGP
QLSTYAVTSLLFETVKKVQKWKQLYPQIQFPQQRLLLAQPQKLAAALPAIAYQKLAQWTTGETTLRQLARYLNRDLVALA
RALLPYIQKGWLQVLDPLPPQSLSRPSEMSSHQTRRILCIDDDFTIGKAVEQILSTQGYQVHLVQNPLEAIQAAFAEVPH
LILCDIAMPHLDGHEICMMLRHSKRFQNVPIIMLTGQEQFINRIQADFAGATDYLTKPFGQQELLTLLEKYLPNH

Sequences:

>Translated_395_residues
MQGNLNEIDLRSILQLLELGQRTGQLWIEARPSGAVDDLSWQFPQAPRFQHSLPLSTWLVFFVNGQIVYGTDDYSPQMYR
LQDYLVHYHLTHKLGDLDRGAIAETTIPEYAALWRLLETQTITVDQARHILQAMVQETLFDLLSLHQGHFNFQLGTPFGP
QLSTYAVTSLLFETVKKVQKWKQLYPQIQFPQQRLLLAQPQKLAAALPAIAYQKLAQWTTGETTLRQLARYLNRDLVALA
RALLPYIQKGWLQVLDPLPPQSLSRPSEMSSHQTRRILCIDDDFTIGKAVEQILSTQGYQVHLVQNPLEAIQAAFAEVPH
LILCDIAMPHLDGHEICMMLRHSKRFQNVPIIMLTGQEQFINRIQADFAGATDYLTKPFGQQELLTLLEKYLPNH
>Mature_395_residues
MQGNLNEIDLRSILQLLELGQRTGQLWIEARPSGAVDDLSWQFPQAPRFQHSLPLSTWLVFFVNGQIVYGTDDYSPQMYR
LQDYLVHYHLTHKLGDLDRGAIAETTIPEYAALWRLLETQTITVDQARHILQAMVQETLFDLLSLHQGHFNFQLGTPFGP
QLSTYAVTSLLFETVKKVQKWKQLYPQIQFPQQRLLLAQPQKLAAALPAIAYQKLAQWTTGETTLRQLARYLNRDLVALA
RALLPYIQKGWLQVLDPLPPQSLSRPSEMSSHQTRRILCIDDDFTIGKAVEQILSTQGYQVHLVQNPLEAIQAAFAEVPH
LILCDIAMPHLDGHEICMMLRHSKRFQNVPIIMLTGQEQFINRIQADFAGATDYLTKPFGQQELLTLLEKYLPNH

Specific function: Member of the two-component regulatory system mprB/mprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a tr

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=35.8974358974359, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082012, Length=120, Percent_Identity=34.1666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789402, Length=114, Percent_Identity=30.7017543859649, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788394, Length=122, Percent_Identity=28.6885245901639, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=31.0924369747899, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 45226; Mature: 45226

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGNLNEIDLRSILQLLELGQRTGQLWIEARPSGAVDDLSWQFPQAPRFQHSLPLSTWLV
CCCCCCHHHHHHHHHHHHHCHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FFVNGQIVYGTDDYSPQMYRLQDYLVHYHLTHKLGDLDRGAIAETTIPEYAALWRLLETQ
HEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
TITVDQARHILQAMVQETLFDLLSLHQGHFNFQLGTPFGPQLSTYAVTSLLFETVKKVQK
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
WKQLYPQIQFPQQRLLLAQPQKLAAALPAIAYQKLAQWTTGETTLRQLARYLNRDLVALA
HHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHH
RALLPYIQKGWLQVLDPLPPQSLSRPSEMSSHQTRRILCIDDDFTIGKAVEQILSTQGYQ
HHHHHHHHHHHHHHHCCCCCHHCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCE
VHLVQNPLEAIQAAFAEVPHLILCDIAMPHLDGHEICMMLRHSKRFQNVPIIMLTGQEQF
EEEECCHHHHHHHHHHHCCCEEEHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHH
INRIQADFAGATDYLTKPFGQQELLTLLEKYLPNH
HHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQGNLNEIDLRSILQLLELGQRTGQLWIEARPSGAVDDLSWQFPQAPRFQHSLPLSTWLV
CCCCCCHHHHHHHHHHHHHCHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FFVNGQIVYGTDDYSPQMYRLQDYLVHYHLTHKLGDLDRGAIAETTIPEYAALWRLLETQ
HEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
TITVDQARHILQAMVQETLFDLLSLHQGHFNFQLGTPFGPQLSTYAVTSLLFETVKKVQK
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
WKQLYPQIQFPQQRLLLAQPQKLAAALPAIAYQKLAQWTTGETTLRQLARYLNRDLVALA
HHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHH
RALLPYIQKGWLQVLDPLPPQSLSRPSEMSSHQTRRILCIDDDFTIGKAVEQILSTQGYQ
HHHHHHHHHHHHHHHCCCCCHHCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCE
VHLVQNPLEAIQAAFAEVPHLILCDIAMPHLDGHEICMMLRHSKRFQNVPIIMLTGQEQF
EEEECCHHHHHHHHHHHCCCEEEHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHH
INRIQADFAGATDYLTKPFGQQELLTLLEKYLPNH
HHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA