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The map label for this gene is sphR [H]

Identifier: 170077988

GI number: 170077988

Start: 1434513

End: 1434908

Strand: Reverse

Name: sphR [H]

Synonym: SYNPCC7002_A1374

Alternate gene names: 170077988

Gene position: 1434908-1434513 (Counterclockwise)

Preceding gene: 170077989

Following gene: 170077987

Centisome position: 47.7

GC content: 46.46

Gene sequence:

>396_bases
ATGAGTAGAATTTTGGTTGTTGAGGATAGCCTCTCTCAACGGGAAATGATTTCAGAATTACTGAAAGGCAACGGCTTGAC
AGTGGATGTTGCCGGTGATGGTCTTGAGGCGTTAGAAACCCTCAGTCAAATGGCTAAAAATGCGGCTGAAACCCTGCCCA
ACTTAATTGTGCTCGACATTGTTATGCCACGGATGAACGGTTACGAACTCTGTCGTCGCCTCAAATCCGACCCAAAAATT
CAAAATATCCCCATTGTGATGTGCTCTTCAAAGGGGGAAGAATTTGACCGGTACTGGGGCATGAAGCAGGGAGCCGACGC
TTATATCGCGAAACCCTTTCAGCCAGCGGAGTTAATTGGCACCATCAAGCAACTCCTACGCAGCAATAAAAAATAA

Upstream 100 bases:

>100_bases
CCCTGATAAATTAAAGTCTGTCCGTCCCAGGGCATGTTTTTGACAATGTTGATGCTACGGTGATTATTACGCCGGTGATT
TTATTGCTAGGACATTTGTA

Downstream 100 bases:

>100_bases
GTTAAGCCCTGGGGAGTAGCCGTTTTGGCGAAACCTGAATTGTCTGTTTTCTTTCGATCTATGTCTACACCTGATGACAG
TTCCTTACCACAAAACCTGA

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MSRILVVEDSLSQREMISELLKGNGLTVDVAGDGLEALETLSQMAKNAAETLPNLIVLDIVMPRMNGYELCRRLKSDPKI
QNIPIVMCSSKGEEFDRYWGMKQGADAYIAKPFQPAELIGTIKQLLRSNKK

Sequences:

>Translated_131_residues
MSRILVVEDSLSQREMISELLKGNGLTVDVAGDGLEALETLSQMAKNAAETLPNLIVLDIVMPRMNGYELCRRLKSDPKI
QNIPIVMCSSKGEEFDRYWGMKQGADAYIAKPFQPAELIGTIKQLLRSNKK
>Mature_130_residues
SRILVVEDSLSQREMISELLKGNGLTVDVAGDGLEALETLSQMAKNAAETLPNLIVLDIVMPRMNGYELCRRLKSDPKIQ
NIPIVMCSSKGEEFDRYWGMKQGADAYIAKPFQPAELIGTIKQLLRSNKK

Specific function: Member of the two-component regulatory system sphR/sphS. Response regulator. Involved in inducible production of alkaline phosphatase in response to phosphate limitation as it is directly involved in the regulation of phoA transcription in response to pho

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=125, Percent_Identity=40.8, Blast_Score=92, Evalue=8e-21,
Organism=Escherichia coli, GI1789809, Length=125, Percent_Identity=36.8, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1788394, Length=128, Percent_Identity=35.15625, Blast_Score=83, Evalue=5e-18,
Organism=Escherichia coli, GI1790860, Length=129, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=3e-17,
Organism=Escherichia coli, GI1786784, Length=125, Percent_Identity=34.4, Blast_Score=73, Evalue=7e-15,
Organism=Escherichia coli, GI1786911, Length=129, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI2367329, Length=130, Percent_Identity=31.5384615384615, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1790863, Length=124, Percent_Identity=33.8709677419355, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI87082012, Length=128, Percent_Identity=27.34375, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14598; Mature: 14467

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILVVEDSLSQREMISELLKGNGLTVDVAGDGLEALETLSQMAKNAAETLPNLIVLDI
CCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHH
VMPRMNGYELCRRLKSDPKIQNIPIVMCSSKGEEFDRYWGMKQGADAYIAKPFQPAELIG
HHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCEEECCCCHHHHHH
TIKQLLRSNKK
HHHHHHHCCCC
>Mature Secondary Structure 
SRILVVEDSLSQREMISELLKGNGLTVDVAGDGLEALETLSQMAKNAAETLPNLIVLDI
CCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHH
VMPRMNGYELCRRLKSDPKIQNIPIVMCSSKGEEFDRYWGMKQGADAYIAKPFQPAELIG
HHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCEEECCCCHHHHHH
TIKQLLRSNKK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497200; 8157591 [H]