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The map label for this gene is phoR [H]

Identifier: 170077968

GI number: 170077968

Start: 1411844

End: 1412962

Strand: Reverse

Name: phoR [H]

Synonym: SYNPCC7002_A1354

Alternate gene names: 170077968

Gene position: 1412962-1411844 (Counterclockwise)

Preceding gene: 170077970

Following gene: 170077967

Centisome position: 46.97

GC content: 50.04

Gene sequence:

>1119_bases
ATGTTTTCGCTGAGCAACCGTGATCGCGTTCTGGTCGTGGATGATTCGCCGGATAATTTATTGTTGATCCAGAGCATTTT
AGAAGATGAAGATTTAGACCTGGTGACGGTTAATAACGGCCAAAAAGCCCTGGAGCTTGTGGCACAGCAGCCTTTTCACC
TGATCTTGCTCGATGTGATGATGCCCCACATGGATGGCTTCGAGATTACACGGCACATTCGTAACGACCCCGACATCCCT
TACATTCCCATCCTGTTGATCACCGCCCATGCTCAACCAAGTGTTGCCCTAGGTTTGGATATTGGTGCCGATGATTTTAT
CCGTAAACCCGTGGAGATTGATGAACTGATTGCCCGGGTGCGATCGCTGCTGCGGTTTAAACATACCGTTGATGAGAAAA
ATATGATTGTCCGGCAACGGGAAGACTTCGCCTCCCGGTTAACCCACGATATGCGCACCCCCTTAATTGCGGCGGATCGG
ATGCTCAATCTCCTTTTGCAGGGGGCTTTGGGGGAACTGTCGGAAGCAATGCAAGAGGTTTTACGCACCATGTCCCGCAG
TAATGCCAATCTGTTGGAGATGGTGAACAATATTTTGGAGGTTTATCGCTACGAATCCGAGCGGAAAACGTTCTATTTTA
GTCGGGTGGATCTCAAGACTGTGATTACCAATGTGCTTGAGGAATTACGTCCCCTCGCCCAGGAAAAACAACTGCAACTC
CAGGGGGAACTCCCCGAAGTCTCCGTGTGGCTCGAAGGCGATCGCCTGGCCATGCATCGCGTTTTAGTGAACCTGGTGAG
CAACGCCATTAAATTTACCGATCAAGGCCACATCACTGTTAAATTGACCCCAGTCGATCAAGAGCAAGTGCAAATTCAAG
TAATCGATACGGGGAGCGGCATTAGCCCGGAAGATCAATTAGAAATCTTTGAGCGATTCCGCCAAGGCAAGCATTACAAC
GGGGGCAGCGGCCTGGGGCTACACCTTTCAAAACTGATCCTCGAAGCCCACCAAGGTCAGATTAGTCTCACCTCCCGTCT
CCAGGAAGGTAGTACCTTTACAATCACCTTGCCCCTCTCCCAAACCCCTGCCCAAAGCGAGGAAAAAAAAGTTGTATGA

Upstream 100 bases:

>100_bases
AAGAAGCAACGCCGTAACCGCCATTGGGTTCAACGTTTAAAATAGGGGATTCCGCTGTTCAACCAGCAGTTGAGTCGAAA
TTAACCTGGGGTGATGTGCC

Downstream 100 bases:

>100_bases
TTGAAGCTCTGCACAGAATATTATTGGCGTACTTGAGCAATTCAGTTCTATGAGCAAAGGCACTCTTTTTGATAAGGTTT
GGGACTTACACACCGTTAAA

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MFSLSNRDRVLVVDDSPDNLLLIQSILEDEDLDLVTVNNGQKALELVAQQPFHLILLDVMMPHMDGFEITRHIRNDPDIP
YIPILLITAHAQPSVALGLDIGADDFIRKPVEIDELIARVRSLLRFKHTVDEKNMIVRQREDFASRLTHDMRTPLIAADR
MLNLLLQGALGELSEAMQEVLRTMSRSNANLLEMVNNILEVYRYESERKTFYFSRVDLKTVITNVLEELRPLAQEKQLQL
QGELPEVSVWLEGDRLAMHRVLVNLVSNAIKFTDQGHITVKLTPVDQEQVQIQVIDTGSGISPEDQLEIFERFRQGKHYN
GGSGLGLHLSKLILEAHQGQISLTSRLQEGSTFTITLPLSQTPAQSEEKKVV

Sequences:

>Translated_372_residues
MFSLSNRDRVLVVDDSPDNLLLIQSILEDEDLDLVTVNNGQKALELVAQQPFHLILLDVMMPHMDGFEITRHIRNDPDIP
YIPILLITAHAQPSVALGLDIGADDFIRKPVEIDELIARVRSLLRFKHTVDEKNMIVRQREDFASRLTHDMRTPLIAADR
MLNLLLQGALGELSEAMQEVLRTMSRSNANLLEMVNNILEVYRYESERKTFYFSRVDLKTVITNVLEELRPLAQEKQLQL
QGELPEVSVWLEGDRLAMHRVLVNLVSNAIKFTDQGHITVKLTPVDQEQVQIQVIDTGSGISPEDQLEIFERFRQGKHYN
GGSGLGLHLSKLILEAHQGQISLTSRLQEGSTFTITLPLSQTPAQSEEKKVV
>Mature_372_residues
MFSLSNRDRVLVVDDSPDNLLLIQSILEDEDLDLVTVNNGQKALELVAQQPFHLILLDVMMPHMDGFEITRHIRNDPDIP
YIPILLITAHAQPSVALGLDIGADDFIRKPVEIDELIARVRSLLRFKHTVDEKNMIVRQREDFASRLTHDMRTPLIAADR
MLNLLLQGALGELSEAMQEVLRTMSRSNANLLEMVNNILEVYRYESERKTFYFSRVDLKTVITNVLEELRPLAQEKQLQL
QGELPEVSVWLEGDRLAMHRVLVNLVSNAIKFTDQGHITVKLTPVDQEQVQIQVIDTGSGISPEDQLEIFERFRQGKHYN
GGSGLGLHLSKLILEAHQGQISLTSRLQEGSTFTITLPLSQTPAQSEEKKVV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=32.2709163346614, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=33.6170212765957, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=29.7071129707113, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=33.0578512396694, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=28.740157480315, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=28.6259541984733, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=31.063829787234, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788394, Length=207, Percent_Identity=31.4009661835749, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=27.9475982532751, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=36.4406779661017, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=26.7399267399267, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=26.4, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=254, Percent_Identity=31.1023622047244, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=129, Percent_Identity=34.1085271317829, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=374, Percent_Identity=24.331550802139, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=261, Percent_Identity=27.9693486590038, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=266, Percent_Identity=24.812030075188, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082012, Length=140, Percent_Identity=31.4285714285714, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=272, Percent_Identity=23.8970588235294, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=261, Percent_Identity=26.4367816091954, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=33.8983050847458, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=30.5343511450382, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789808, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=31.8965517241379, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=30.5084745762712, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790860, Length=134, Percent_Identity=30.5970149253731, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI2367329, Length=126, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790552, Length=132, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1786911, Length=144, Percent_Identity=29.8611111111111, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42176; Mature: 42176

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSLSNRDRVLVVDDSPDNLLLIQSILEDEDLDLVTVNNGQKALELVAQQPFHLILLDVM
CCCCCCCCEEEEEECCCCCEEHHHHHHCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHH
MPHMDGFEITRHIRNDPDIPYIPILLITAHAQPSVALGLDIGADDFIRKPVEIDELIARV
HCCCCCHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEEEECCCHHHHCCCCCHHHHHHHH
RSLLRFKHTVDEKNMIVRQREDFASRLTHDMRTPLIAADRMLNLLLQGALGELSEAMQEV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTMSRSNANLLEMVNNILEVYRYESERKTFYFSRVDLKTVITNVLEELRPLAQEKQLQL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
QGELPEVSVWLEGDRLAMHRVLVNLVSNAIKFTDQGHITVKLTPVDQEQVQIQVIDTGSG
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCEEEEEEEECCCC
ISPEDQLEIFERFRQGKHYNGGSGLGLHLSKLILEAHQGQISLTSRLQEGSTFTITLPLS
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCEEEEEEECC
QTPAQSEEKKVV
CCCCCCCCCCCC
>Mature Secondary Structure
MFSLSNRDRVLVVDDSPDNLLLIQSILEDEDLDLVTVNNGQKALELVAQQPFHLILLDVM
CCCCCCCCEEEEEECCCCCEEHHHHHHCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHH
MPHMDGFEITRHIRNDPDIPYIPILLITAHAQPSVALGLDIGADDFIRKPVEIDELIARV
HCCCCCHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEEEECCCHHHHCCCCCHHHHHHHH
RSLLRFKHTVDEKNMIVRQREDFASRLTHDMRTPLIAADRMLNLLLQGALGELSEAMQEV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTMSRSNANLLEMVNNILEVYRYESERKTFYFSRVDLKTVITNVLEELRPLAQEKQLQL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
QGELPEVSVWLEGDRLAMHRVLVNLVSNAIKFTDQGHITVKLTPVDQEQVQIQVIDTGSG
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCEEEEEEEECCCC
ISPEDQLEIFERFRQGKHYNGGSGLGLHLSKLILEAHQGQISLTSRLQEGSTFTITLPLS
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHCCCCEEEEEEECC
QTPAQSEEKKVV
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]