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The map label for this gene is ppib [C]

Identifier: 170077712

GI number: 170077712

Start: 1122421

End: 1123191

Strand: Reverse

Name: ppib [C]

Synonym: SYNPCC7002_A1092

Alternate gene names: 170077712

Gene position: 1123191-1122421 (Counterclockwise)

Preceding gene: 170077713

Following gene: 170077711

Centisome position: 37.34

GC content: 54.09

Gene sequence:

>771_bases
ATGGAACGACCTTGGCAGCTACTATGTCTCGCACTCTTGGTGGGCAGCCTCAGCTTGAGTGGCTGTGCGCCGACAACGGA
AACATCTTCCAATAATCCAACGGCCACCCCACCCAGTGCCGAAAATTATAAGCCCCGTTTAAATTGCCCGAATCCAGCTT
CTACCGAGGCCACCCCAGAAGATAGCTGTACAGCGGTGGTCGAAATGGTACTCCAGAGCCAATCTGAAGCAGTGGATGGC
CAAACGATCCGCATTGAACTCAATGGTGCAGATGCGCCAGTGACGGCGGGAAATTTTGTGGATTTAGTCAGCCGTGGCGT
CTATGATGGCACCGCTTTCCACCGGGTAATTCGGACGCCGGAACCCTTTGTTGTCCAAGGGGGAGACCCCCTCAGTAAGG
ACAGCCAAGTGCCCCTCAATGCCCTCGGTCGCGGGGGATTTGTCGATCCAGAGACCGGGATTCGTCGGGATGTCCCCCTA
GAAATTAAGCTCCAGGGTGAGGAACAGCCCGTTTATGGCAAGGCAGAACTTGATCCGAATCAGGTGGTGCTTAAGCATGA
CAAAGGGGCGATCGCCATGGCCCGTTCCCAACTGCCGAACTCCGCCTCGTCTCAGTTTTATTTTTCCTTGGGGCCGAATG
ATTTCCTCAATGGGAACTATGCAGTGTTTGGCCAAATTACCGAGGGTCTTGCGGTGATCGACAAAATTGAAATGGGCGAT
CGCATTCAATCGGCGCGGGTTGTCGAAGGAGAAGATCTCCTCGTGAAGTAA

Upstream 100 bases:

>100_bases
CTAAGCACCTGAGACGAAAAAAAGACAGTGGGCGATCGCCTTCGCTGCTTCCTATAATTTTTCCAGGTTTTATCTAAAAC
AAAAGTACGACTAAATTTCT

Downstream 100 bases:

>100_bases
AAAAGGACTAGGTCGCGTTTGAGCATTACCACGTCCCGCAACAGTTCAAAATATTGCCAGTGATCCAAATCTATCTGGGT
CACTTTTTTGTTGGCAAATA

Product: peptidyl-prolyl cis-trans isomerase B, cyclophilin type

Products: NA

Alternate protein names: PPIase sll0227; Rotamase sll0227 [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MERPWQLLCLALLVGSLSLSGCAPTTETSSNNPTATPPSAENYKPRLNCPNPASTEATPEDSCTAVVEMVLQSQSEAVDG
QTIRIELNGADAPVTAGNFVDLVSRGVYDGTAFHRVIRTPEPFVVQGGDPLSKDSQVPLNALGRGGFVDPETGIRRDVPL
EIKLQGEEQPVYGKAELDPNQVVLKHDKGAIAMARSQLPNSASSQFYFSLGPNDFLNGNYAVFGQITEGLAVIDKIEMGD
RIQSARVVEGEDLLVK

Sequences:

>Translated_256_residues
MERPWQLLCLALLVGSLSLSGCAPTTETSSNNPTATPPSAENYKPRLNCPNPASTEATPEDSCTAVVEMVLQSQSEAVDG
QTIRIELNGADAPVTAGNFVDLVSRGVYDGTAFHRVIRTPEPFVVQGGDPLSKDSQVPLNALGRGGFVDPETGIRRDVPL
EIKLQGEEQPVYGKAELDPNQVVLKHDKGAIAMARSQLPNSASSQFYFSLGPNDFLNGNYAVFGQITEGLAVIDKIEMGD
RIQSARVVEGEDLLVK
>Mature_256_residues
MERPWQLLCLALLVGSLSLSGCAPTTETSSNNPTATPPSAENYKPRLNCPNPASTEATPEDSCTAVVEMVLQSQSEAVDG
QTIRIELNGADAPVTAGNFVDLVSRGVYDGTAFHRVIRTPEPFVVQGGDPLSKDSQVPLNALGRGGFVDPETGIRRDVPL
EIKLQGEEQPVYGKAELDPNQVVLKHDKGAIAMARSQLPNSASSQFYFSLGPNDFLNGNYAVFGQITEGLAVIDKIEMGD
RIQSARVVEGEDLLVK

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=156, Percent_Identity=30.1282051282051, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19557636, Length=156, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789763, Length=160, Percent_Identity=33.75, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786736, Length=154, Percent_Identity=32.4675324675325, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17506311, Length=155, Percent_Identity=30.9677419354839, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17986117, Length=168, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 27396; Mature: 27396

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERPWQLLCLALLVGSLSLSGCAPTTETSSNNPTATPPSAENYKPRLNCPNPASTEATPE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DSCTAVVEMVLQSQSEAVDGQTIRIELNGADAPVTAGNFVDLVSRGVYDGTAFHRVIRTP
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCHHHHHHHCCC
EPFVVQGGDPLSKDSQVPLNALGRGGFVDPETGIRRDVPLEIKLQGEEQPVYGKAELDPN
CCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEECCCCCCC
QVVLKHDKGAIAMARSQLPNSASSQFYFSLGPNDFLNGNYAVFGQITEGLAVIDKIEMGD
EEEEEECCCCEEEHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEHHCCHHHHHHHCCCC
RIQSARVVEGEDLLVK
CCCCCEEECCCCEEEC
>Mature Secondary Structure
MERPWQLLCLALLVGSLSLSGCAPTTETSSNNPTATPPSAENYKPRLNCPNPASTEATPE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DSCTAVVEMVLQSQSEAVDGQTIRIELNGADAPVTAGNFVDLVSRGVYDGTAFHRVIRTP
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCHHHHHHHCCC
EPFVVQGGDPLSKDSQVPLNALGRGGFVDPETGIRRDVPLEIKLQGEEQPVYGKAELDPN
CCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEECCCCCCC
QVVLKHDKGAIAMARSQLPNSASSQFYFSLGPNDFLNGNYAVFGQITEGLAVIDKIEMGD
EEEEEECCCCEEEHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEHHCCHHHHHHHCCCC
RIQSARVVEGEDLLVK
CCCCCEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]