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The map label for this gene is crtE [C]

Identifier: 170077705

GI number: 170077705

Start: 1114272

End: 1115180

Strand: Reverse

Name: crtE [C]

Synonym: SYNPCC7002_A1085

Alternate gene names: 170077705

Gene position: 1115180-1114272 (Counterclockwise)

Preceding gene: 170077708

Following gene: 170077704

Centisome position: 37.07

GC content: 54.02

Gene sequence:

>909_bases
ATGGTAGTTGCAGACGCTCACACCCAGGGCTTTTCCCTCGCGCAATATCTCCAAGAACAAAAGACCATCGTCGAAACCGC
CCTTGACCAATCCTTAGTTATCACTGAGCCTGTCACCATCTACGAAGCCATGCGCTATTCCCTCCTGGCTGGGGGAAAAC
GGCTACGCCCGATTCTTTGTCTTGCCGCCTGTGAAATGTTGGGGGGCACCGCCGCCATGGCGATGAATACGGCCTGTGCC
CTGGAGATGATCCACACCATGTCTTTAATCCATGATGATCTGCCCGCCATGGACAATGACGATCTCCGTCGGGGCAAACC
CACGAACCATAAAGTTTATGGGGAAGATATTGCCATTTTGGCGGGGGATGCCCTGCTCTCCTATGCCTTTGAGTATGTGG
CCCGCACCCCGGATGTTCCGGCGGAACGTCTGTTGCAAGTGATCGTACGCCTCGGCCAAGCGGTGGGGGCCGAAGGCCTC
GTCGGTGGCCAAGTGGTGGATCTCGAATCGGAAGGGAAAACCGATGTTGCCGTAGAAACCCTGAATTTTATCCATACCCA
TAAAACAGGGGCATTGCTGGAAGTTTGCGTCACGGCGGGGGCAATTTTGGCCGGGGCGAAACCGGAAGAGGTGCAATTAC
TCTCCCGTTATGCCCAAAATATTGGTCTGGCTTTCCAGATTGTCGATGATATTCTCGATATCACTGCCACAGCGGAGGAA
CTAGGTAAAACGGCAGGCAAAGACCTCGAAGCCCAGAAAGTGACTTATCCGAGCCTATGGGGTATTGAAAAATCCCAGGC
TGAGGCCCAGAAGCTGGTGGCAGAGGCGATCGCCTCCCTCGAACCCTATGGTGAAAAGGCCAATCCCCTCAAAGCCCTGG
CGGAATACATCGTTAACCGTAAAAACTAA

Upstream 100 bases:

>100_bases
TAGCACCCCTCTGCAAGCAACCCAGGATGATTCCCCCAGACTTGCCCCCAAAGCCCTGTAGAATATTCTTGAAAAAATCA
ACAGTTTTCCAAACGTAGCT

Downstream 100 bases:

>100_bases
CCCGCGTCACGGCCAAGCACCATGGATAATTTCAGCGCAGTTTTCCAAAATCACATCCTGATTGTGGCATTAGTGGCCTG
CATTACGGCACAGTTGCTTA

Product: geranylgeranyl pyrophosphate synthase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVVADAHTQGFSLAQYLQEQKTIVETALDQSLVITEPVTIYEAMRYSLLAGGKRLRPILCLAACEMLGGTAAMAMNTACA
LEMIHTMSLIHDDLPAMDNDDLRRGKPTNHKVYGEDIAILAGDALLSYAFEYVARTPDVPAERLLQVIVRLGQAVGAEGL
VGGQVVDLESEGKTDVAVETLNFIHTHKTGALLEVCVTAGAILAGAKPEEVQLLSRYAQNIGLAFQIVDDILDITATAEE
LGKTAGKDLEAQKVTYPSLWGIEKSQAEAQKLVAEAIASLEPYGEKANPLKALAEYIVNRKN

Sequences:

>Translated_302_residues
MVVADAHTQGFSLAQYLQEQKTIVETALDQSLVITEPVTIYEAMRYSLLAGGKRLRPILCLAACEMLGGTAAMAMNTACA
LEMIHTMSLIHDDLPAMDNDDLRRGKPTNHKVYGEDIAILAGDALLSYAFEYVARTPDVPAERLLQVIVRLGQAVGAEGL
VGGQVVDLESEGKTDVAVETLNFIHTHKTGALLEVCVTAGAILAGAKPEEVQLLSRYAQNIGLAFQIVDDILDITATAEE
LGKTAGKDLEAQKVTYPSLWGIEKSQAEAQKLVAEAIASLEPYGEKANPLKALAEYIVNRKN
>Mature_302_residues
MVVADAHTQGFSLAQYLQEQKTIVETALDQSLVITEPVTIYEAMRYSLLAGGKRLRPILCLAACEMLGGTAAMAMNTACA
LEMIHTMSLIHDDLPAMDNDDLRRGKPTNHKVYGEDIAILAGDALLSYAFEYVARTPDVPAERLLQVIVRLGQAVGAEGL
VGGQVVDLESEGKTDVAVETLNFIHTHKTGALLEVCVTAGAILAGAKPEEVQLLSRYAQNIGLAFQIVDDILDITATAEE
LGKTAGKDLEAQKVTYPSLWGIEKSQAEAQKLVAEAIASLEPYGEKANPLKALAEYIVNRKN

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=235, Percent_Identity=34.0425531914894, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1786623, Length=269, Percent_Identity=45.724907063197, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1789578, Length=254, Percent_Identity=32.2834645669291, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17505681, Length=187, Percent_Identity=32.0855614973262, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24651612, Length=232, Percent_Identity=31.0344827586207, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 32478; Mature: 32478

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVADAHTQGFSLAQYLQEQKTIVETALDQSLVITEPVTIYEAMRYSLLAGGKRLRPILC
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHH
LAACEMLGGTAAMAMNTACALEMIHTMSLIHDDLPAMDNDDLRRGKPTNHKVYGEDIAIL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCEEEE
AGDALLSYAFEYVARTPDVPAERLLQVIVRLGQAVGAEGLVGGQVVDLESEGKTDVAVET
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHH
LNFIHTHKTGALLEVCVTAGAILAGAKPEEVQLLSRYAQNIGLAFQIVDDILDITATAEE
HHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LGKTAGKDLEAQKVTYPSLWGIEKSQAEAQKLVAEAIASLEPYGEKANPLKALAEYIVNR
HHHHCCCCCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
KN
CC
>Mature Secondary Structure
MVVADAHTQGFSLAQYLQEQKTIVETALDQSLVITEPVTIYEAMRYSLLAGGKRLRPILC
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHH
LAACEMLGGTAAMAMNTACALEMIHTMSLIHDDLPAMDNDDLRRGKPTNHKVYGEDIAIL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCEEEE
AGDALLSYAFEYVARTPDVPAERLLQVIVRLGQAVGAEGLVGGQVVDLESEGKTDVAVET
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHH
LNFIHTHKTGALLEVCVTAGAILAGAKPEEVQLLSRYAQNIGLAFQIVDDILDITATAEE
HHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LGKTAGKDLEAQKVTYPSLWGIEKSQAEAQKLVAEAIASLEPYGEKANPLKALAEYIVNR
HHHHCCCCCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
KN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486607; 7918490 [H]