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The map label for this gene is fabF [H]

Identifier: 170077644

GI number: 170077644

Start: 1062649

End: 1063905

Strand: Reverse

Name: fabF [H]

Synonym: SYNPCC7002_A1023

Alternate gene names: 170077644

Gene position: 1063905-1062649 (Counterclockwise)

Preceding gene: 170077645

Following gene: 170077643

Centisome position: 35.37

GC content: 54.1

Gene sequence:

>1257_bases
ATGGCACACTCATCTCCGTATCGCGTTGTAATCACCGGTTTAGGTGCGATCACCCCGATTGGTAATACCCTAGAGGAGTA
TTGGGAAGGACTCATGACCGGTCGCAATGGCATTGACCTCGTGACCGCATTTGACGCTTCCCAACATGCCTGTCGCATTG
CAGGTGAAGTAAAAGGCTTTGATCCCCTCGCATTCATCCCGAAAAAAGAAGCGAAACGCATGGATCGGTTCTCCCAGTTC
GCCGTGGCTGCCAGTAAACAAGCCCTCGCCGATGCTGGCCTAGAGATCAATGCTGACAATGCCCCCGATATCGGCGTAAT
GATCGGCACTGGCGTCGGCGGGATTAAGGTGATGGAAGACCAGCAGGAAATTTACCTGGAGAAAGGCCCCAGCCGCTGTA
GCCCCTTCATGATTCCGATGATGATTGCTAATATGGCGGCGGGATTGACGGCGATCCATACCGGTGCCCAAGGCCCCAAT
AGCTGTACTGTGACGGCCTGTGCCGCAGGTTCCAATGCGGTTGGGGAAGCTTTCCGACTCGTCCAACAGGGTTACGCGAA
AGCGATGATTTCTGGGGGCACCGAGGCAGCTGTAACCCCCCTCAGTTTTGCGGGATTTGCCTCGGCCCGGGCGTTATCGA
CCCGTAATGATGATCCGAAACACGCTTGTCGTCCTTTTGATCAAGATCGCGATGGCTTTGTGATGGGTGAAGGGGCGGGC
ATTTTAATCCTGGAAGAGCTAGAGCATGCCCTGGCACGGGGGGCAAAAATCTACGGGGAAATCGTTGGTTATGGCATGAC
CTGCGATGCTTACCACATGACGGCACCGACCCCCGACGGCGCTGGGGCAACCCGGGCGATTGAATTGGCGCTCAAGGATG
GCGGCTTGGCTCCGAACCAAGTGAACTACGTGAATGCCCACGGCACCAGCACTCCAGCCAATGACATCACAGAAACAAAA
GCGATTAAAAAAGCCCTCGGTGACCAGGCTTACAAAATTTTAGTGAGTTCGACAAAATCTATGACCGGTCACCTTTTGGG
TGGCTCTGGGGGCATTGAGGCGGTGGCCACAGTGATGGCGATCGCAAATGATCGCGTTCCGCCGACGATCAACCTCGAAA
ATCCCCAGGAAGGTTGTGATTTAGATTACGTTCCCAACGAAAGCCGCGAACACCCAGTTGAAGTTGCCCTTTCTAACTCT
TTTGGATTTGGCGGCCATAACGTTACCCTTGCGTTTAAGAAATATCGCCCGGAATAA

Upstream 100 bases:

>100_bases
CAAAAGTTATCGCGGCTTTCTCGCTAGTTTTTATGATTGATTGTCGCTTCCTTTGGATGCACAAGCCTTTTTTCCCACTG
CAAAACCACTCAAATCAGCC

Downstream 100 bases:

>100_bases
AAATTTAGTCCGAGTAAATGTTAGCGATTTGACAGAATCATTCTTGCCCAGTGATCCTAACAGTGGGATGATGGGGGGGA
TTTTGAGGAGGGCAATTTGC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MAHSSPYRVVITGLGAITPIGNTLEEYWEGLMTGRNGIDLVTAFDASQHACRIAGEVKGFDPLAFIPKKEAKRMDRFSQF
AVAASKQALADAGLEINADNAPDIGVMIGTGVGGIKVMEDQQEIYLEKGPSRCSPFMIPMMIANMAAGLTAIHTGAQGPN
SCTVTACAAGSNAVGEAFRLVQQGYAKAMISGGTEAAVTPLSFAGFASARALSTRNDDPKHACRPFDQDRDGFVMGEGAG
ILILEELEHALARGAKIYGEIVGYGMTCDAYHMTAPTPDGAGATRAIELALKDGGLAPNQVNYVNAHGTSTPANDITETK
AIKKALGDQAYKILVSSTKSMTGHLLGGSGGIEAVATVMAIANDRVPPTINLENPQEGCDLDYVPNESREHPVEVALSNS
FGFGGHNVTLAFKKYRPE

Sequences:

>Translated_418_residues
MAHSSPYRVVITGLGAITPIGNTLEEYWEGLMTGRNGIDLVTAFDASQHACRIAGEVKGFDPLAFIPKKEAKRMDRFSQF
AVAASKQALADAGLEINADNAPDIGVMIGTGVGGIKVMEDQQEIYLEKGPSRCSPFMIPMMIANMAAGLTAIHTGAQGPN
SCTVTACAAGSNAVGEAFRLVQQGYAKAMISGGTEAAVTPLSFAGFASARALSTRNDDPKHACRPFDQDRDGFVMGEGAG
ILILEELEHALARGAKIYGEIVGYGMTCDAYHMTAPTPDGAGATRAIELALKDGGLAPNQVNYVNAHGTSTPANDITETK
AIKKALGDQAYKILVSSTKSMTGHLLGGSGGIEAVATVMAIANDRVPPTINLENPQEGCDLDYVPNESREHPVEVALSNS
FGFGGHNVTLAFKKYRPE
>Mature_417_residues
AHSSPYRVVITGLGAITPIGNTLEEYWEGLMTGRNGIDLVTAFDASQHACRIAGEVKGFDPLAFIPKKEAKRMDRFSQFA
VAASKQALADAGLEINADNAPDIGVMIGTGVGGIKVMEDQQEIYLEKGPSRCSPFMIPMMIANMAAGLTAIHTGAQGPNS
CTVTACAAGSNAVGEAFRLVQQGYAKAMISGGTEAAVTPLSFAGFASARALSTRNDDPKHACRPFDQDRDGFVMGEGAGI
LILEELEHALARGAKIYGEIVGYGMTCDAYHMTAPTPDGAGATRAIELALKDGGLAPNQVNYVNAHGTSTPANDITETKA
IKKALGDQAYKILVSSTKSMTGHLLGGSGGIEAVATVMAIANDRVPPTINLENPQEGCDLDYVPNESREHPVEVALSNSF
GFGGHNVTLAFKKYRPE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=413, Percent_Identity=44.5520581113801, Blast_Score=352, Evalue=5e-97,
Organism=Homo sapiens, GI223972627, Length=164, Percent_Identity=46.9512195121951, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI41872631, Length=426, Percent_Identity=26.7605633802817, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=51.5815085158151, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1788663, Length=412, Percent_Identity=35.9223300970874, Blast_Score=236, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=36.7788461538462, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=41.0852713178295, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=426, Percent_Identity=24.8826291079812, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=427, Percent_Identity=22.7166276346604, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=36.241610738255, Blast_Score=283, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24644341, Length=422, Percent_Identity=43.3649289099526, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI19920632, Length=427, Percent_Identity=25.0585480093677, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221330659, Length=427, Percent_Identity=25.0585480093677, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24581345, Length=430, Percent_Identity=24.4186046511628, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43867; Mature: 43736

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSSPYRVVITGLGAITPIGNTLEEYWEGLMTGRNGIDLVTAFDASQHACRIAGEVKGF
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEHHCCCCCC
DPLAFIPKKEAKRMDRFSQFAVAASKQALADAGLEINADNAPDIGVMIGTGVGGIKVMED
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCEEEECC
QQEIYLEKGPSRCSPFMIPMMIANMAAGLTAIHTGAQGPNSCTVTACAAGSNAVGEAFRL
CHHHHHHCCCCCCCCHHHHHHHHHHHHCHHEEECCCCCCCCEEEEEECCCCCHHHHHHHH
VQQGYAKAMISGGTEAAVTPLSFAGFASARALSTRNDDPKHACRPFDQDRDGFVMGEGAG
HHHHHHHHHHCCCCCCEECCHHHHCCHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCC
ILILEELEHALARGAKIYGEIVGYGMTCDAYHMTAPTPDGAGATRAIELALKDGGLAPNQ
EEEHHHHHHHHHCCHHHHHHHHCCCCEECCEEECCCCCCCCCCCEEEEEEEECCCCCCCC
VNYVNAHGTSTPANDITETKAIKKALGDQAYKILVSSTKSMTGHLLGGSGGIEAVATVMA
EEEEECCCCCCCCCHHHHHHHHHHHHCHHHEEHEECCCCCCCEEEECCCCCHHHHHHHHH
IANDRVPPTINLENPQEGCDLDYVPNESREHPVEVALSNSFGFGGHNVTLAFKKYRPE
HHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
AHSSPYRVVITGLGAITPIGNTLEEYWEGLMTGRNGIDLVTAFDASQHACRIAGEVKGF
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEHHCCCCCC
DPLAFIPKKEAKRMDRFSQFAVAASKQALADAGLEINADNAPDIGVMIGTGVGGIKVMED
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCEEEECC
QQEIYLEKGPSRCSPFMIPMMIANMAAGLTAIHTGAQGPNSCTVTACAAGSNAVGEAFRL
CHHHHHHCCCCCCCCHHHHHHHHHHHHCHHEEECCCCCCCCEEEEEECCCCCHHHHHHHH
VQQGYAKAMISGGTEAAVTPLSFAGFASARALSTRNDDPKHACRPFDQDRDGFVMGEGAG
HHHHHHHHHHCCCCCCEECCHHHHCCHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCC
ILILEELEHALARGAKIYGEIVGYGMTCDAYHMTAPTPDGAGATRAIELALKDGGLAPNQ
EEEHHHHHHHHHCCHHHHHHHHCCCCEECCEEECCCCCCCCCCCEEEEEEEECCCCCCCC
VNYVNAHGTSTPANDITETKAIKKALGDQAYKILVSSTKSMTGHLLGGSGGIEAVATVMA
EEEEECCCCCCCCCHHHHHHHHHHHHCHHHEEHEECCCCCCCEEEECCCCCHHHHHHHHH
IANDRVPPTINLENPQEGCDLDYVPNESREHPVEVALSNSFGFGGHNVTLAFKKYRPE
HHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231; 11152607 [H]