Click here to switch to the map view.

The map label for this gene is yjcE [C]

Identifier: 170077624

GI number: 170077624

Start: 1035205

End: 1036827

Strand: Direct

Name: yjcE [C]

Synonym: SYNPCC7002_A1003

Alternate gene names: 170077624

Gene position: 1035205-1036827 (Clockwise)

Preceding gene: 170077622

Following gene: 170077627

Centisome position: 34.41

GC content: 51.02

Gene sequence:

>1623_bases
GTGCCCAATCCTCCCCTGATCATTGTGCGCCACATCTTCCTGTTCGGACAAGCGGTTTCTTTGCCGGCCAATGCCTTTAC
CGGATTGGTGAATACTTTAATTTTGTTGCTGTTGGTGGCGACGGTCGTGGCACTGGTGACCCGCTGGCTCAGGATTCCCT
ACGTGATTGGTCTGGTGCTGGCAGGGTTGTTGATCCCCAAACAAATTCTCTCCGATGCCATTGGCTTGAATCCTGAGGTT
ATTCTCAATTTATTCTTGCCGATTCTAATTTTTGAGGCGGCGATCAATACTGATATCAGTCGTTTGCGCAGCACCATTAA
ACCGATTGCCCTTTTAGCGGGGCCTGGGGTGCTTTTGGCGGCGACGATCACCGCTTTTTTCCTGAAGGTCAGTTTAGATT
TAGCTTGGCTAACGGCCTGTGCGGTGGGCGTGATCCTCACGATTACAGATACGGTGTCGGTGATTGCGGCCTTTCGGACG
GTGCCAGTACCGGGGCGACTGGCGACCATTGTGGAAGGGGAAAGTTTGTTTAACGATGGGATTGCCCTTGTTCTACTGAA
TATTGTGACCACCATTCATCTGCAAGGCTCGTTTAGCGTCGGGGAAGGGGTTGAACAAATTTTAATTGCCTTTGTGGGGG
GTGGCTTGCTGGGCCTGGGTCTGGGTTATTTGTGCATTGGTCTGTTCCGGCAATTGGATGATCCCCTCAGTAATATTTTG
TTGACGGTGGCGGTCTCCCTGGGCACCTTTCAAATTGGTCAGGCCCTAGGGGTTTCTAGTGCGATCGCCGTGTTGATCGC
GGGACTTTTGATCGGCAACGTGGCGCTGCGAGAATGTTCCGGTTCCGTGACGATTACGCTCCTGAATTTCTGGGAATATG
CGGGATTTGGAGTGAATACCTTCATTTTTTTGTTTGTGGGGATTGAGGTCGCCCCTTTATCGTTGTTACAGACAATTCCG
GCGGCTTTACTGGCGGTGGTGGCCTATCAAGTGGGGCGAATTTGTTCGATTTATCCTCTGCTGTCGGTGCTGAAATTTTT
TGACCGTCCCTTGCCCCTCCGCTGGCAGCACGTACTCATTTTCGGTAATGTCAAAGGCTCTTTATCCATGGCCCTCGCCC
TCGGCTTGCCTTTAACCCTCCAGGGGCGATCGCAGGTGATTACCCTCGTGTTTAGTACCGTCCTAGTTTCCCTGATTGGT
CAAGGTTTGAGCTTGCCTTGGTTCGTGAAAAAGCTCCAACTCGCCAAGCCTTCCCCCGTCCGCCAACACCTCGAAAATTT
GCAACTCAATCTAATCGCCGCCAAATCTGCCCAGGAAGAACTCAAGGAACTGTTGCAGAGTGGCAGTTTGCCGAAATTTC
TCTACGAAGAACTCTTTGCCAGTTACCAAGCCCGCATTGCCAACGCCGAGGAAGAGTTACGGGGACTTTATAATCAACGC
CTCACCCAAAAGTTAAGCCAGTTTGAGAACCAAGCTTATTTAGAAGGCTTGCGCCATCGCCTCTTTCTCGCGGAAAAAAG
TGCCATTAACGAAGCAATTCTCAAGGGCTTAATTAGTGATGAGACGGCCCGGCCGTACTTACAGGAGTTAAACCAAAAAA
TTCTGGCCCTGCGAGATCCCTAG

Upstream 100 bases:

>100_bases
ACTAAGCATCAAAAATTTTGCGTCAGCCTGTCGATTTCTGGCGATCGCCGTTACCGTAGGATGTTGCAACCGATTATTCT
CACCAAGGAAACTTACCACC

Downstream 100 bases:

>100_bases
GCAACACATAACCCCATAAAGTCCACTAATTGGTGTACCAGTTCTGGTTTGGTGACAGCTAGGATTGTCGAACCGCTTTC
TAGGAGTGTACTGCCGTTGG

Product: Na+/H+-exchanging protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MPNPPLIIVRHIFLFGQAVSLPANAFTGLVNTLILLLLVATVVALVTRWLRIPYVIGLVLAGLLIPKQILSDAIGLNPEV
ILNLFLPILIFEAAINTDISRLRSTIKPIALLAGPGVLLAATITAFFLKVSLDLAWLTACAVGVILTITDTVSVIAAFRT
VPVPGRLATIVEGESLFNDGIALVLLNIVTTIHLQGSFSVGEGVEQILIAFVGGGLLGLGLGYLCIGLFRQLDDPLSNIL
LTVAVSLGTFQIGQALGVSSAIAVLIAGLLIGNVALRECSGSVTITLLNFWEYAGFGVNTFIFLFVGIEVAPLSLLQTIP
AALLAVVAYQVGRICSIYPLLSVLKFFDRPLPLRWQHVLIFGNVKGSLSMALALGLPLTLQGRSQVITLVFSTVLVSLIG
QGLSLPWFVKKLQLAKPSPVRQHLENLQLNLIAAKSAQEELKELLQSGSLPKFLYEELFASYQARIANAEEELRGLYNQR
LTQKLSQFENQAYLEGLRHRLFLAEKSAINEAILKGLISDETARPYLQELNQKILALRDP

Sequences:

>Translated_540_residues
MPNPPLIIVRHIFLFGQAVSLPANAFTGLVNTLILLLLVATVVALVTRWLRIPYVIGLVLAGLLIPKQILSDAIGLNPEV
ILNLFLPILIFEAAINTDISRLRSTIKPIALLAGPGVLLAATITAFFLKVSLDLAWLTACAVGVILTITDTVSVIAAFRT
VPVPGRLATIVEGESLFNDGIALVLLNIVTTIHLQGSFSVGEGVEQILIAFVGGGLLGLGLGYLCIGLFRQLDDPLSNIL
LTVAVSLGTFQIGQALGVSSAIAVLIAGLLIGNVALRECSGSVTITLLNFWEYAGFGVNTFIFLFVGIEVAPLSLLQTIP
AALLAVVAYQVGRICSIYPLLSVLKFFDRPLPLRWQHVLIFGNVKGSLSMALALGLPLTLQGRSQVITLVFSTVLVSLIG
QGLSLPWFVKKLQLAKPSPVRQHLENLQLNLIAAKSAQEELKELLQSGSLPKFLYEELFASYQARIANAEEELRGLYNQR
LTQKLSQFENQAYLEGLRHRLFLAEKSAINEAILKGLISDETARPYLQELNQKILALRDP
>Mature_539_residues
PNPPLIIVRHIFLFGQAVSLPANAFTGLVNTLILLLLVATVVALVTRWLRIPYVIGLVLAGLLIPKQILSDAIGLNPEVI
LNLFLPILIFEAAINTDISRLRSTIKPIALLAGPGVLLAATITAFFLKVSLDLAWLTACAVGVILTITDTVSVIAAFRTV
PVPGRLATIVEGESLFNDGIALVLLNIVTTIHLQGSFSVGEGVEQILIAFVGGGLLGLGLGYLCIGLFRQLDDPLSNILL
TVAVSLGTFQIGQALGVSSAIAVLIAGLLIGNVALRECSGSVTITLLNFWEYAGFGVNTFIFLFVGIEVAPLSLLQTIPA
ALLAVVAYQVGRICSIYPLLSVLKFFDRPLPLRWQHVLIFGNVKGSLSMALALGLPLTLQGRSQVITLVFSTVLVSLIGQ
GLSLPWFVKKLQLAKPSPVRQHLENLQLNLIAAKSAQEELKELLQSGSLPKFLYEELFASYQARIANAEEELRGLYNQRL
TQKLSQFENQAYLEGLRHRLFLAEKSAINEAILKGLISDETARPYLQELNQKILALRDP

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI27734935, Length=413, Percent_Identity=24.455205811138, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI41872703, Length=439, Percent_Identity=22.3234624145786, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI14211919, Length=418, Percent_Identity=24.1626794258373, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI5454070, Length=393, Percent_Identity=25.4452926208651, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI294997330, Length=353, Percent_Identity=26.3456090651558, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI110227626, Length=353, Percent_Identity=26.3456090651558, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI148727259, Length=367, Percent_Identity=22.3433242506812, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790501, Length=554, Percent_Identity=22.7436823104693, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71992107, Length=403, Percent_Identity=22.8287841191067, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71992101, Length=403, Percent_Identity=22.8287841191067, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71993590, Length=411, Percent_Identity=24.0875912408759, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71993582, Length=413, Percent_Identity=24.2130750605327, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71980847, Length=396, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=354, Percent_Identity=23.4463276836158, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221473215, Length=395, Percent_Identity=24.0506329113924, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281360447, Length=354, Percent_Identity=23.728813559322, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364513, Length=386, Percent_Identity=24.3523316062176, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221473212, Length=390, Percent_Identity=23.8461538461538, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221473222, Length=386, Percent_Identity=24.3523316062176, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 58352; Mature: 58221

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNPPLIIVRHIFLFGQAVSLPANAFTGLVNTLILLLLVATVVALVTRWLRIPYVIGLVL
CCCCCEEHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLLIPKQILSDAIGLNPEVILNLFLPILIFEAAINTDISRLRSTIKPIALLAGPGVLLA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ATITAFFLKVSLDLAWLTACAVGVILTITDTVSVIAAFRTVPVPGRLATIVEGESLFNDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHCC
IALVLLNIVTTIHLQGSFSVGEGVEQILIAFVGGGLLGLGLGYLCIGLFRQLDDPLSNIL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH
LTVAVSLGTFQIGQALGVSSAIAVLIAGLLIGNVALRECSGSVTITLLNFWEYAGFGVNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHH
FIFLFVGIEVAPLSLLQTIPAALLAVVAYQVGRICSIYPLLSVLKFFDRPLPLRWQHVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
FGNVKGSLSMALALGLPLTLQGRSQVITLVFSTVLVSLIGQGLSLPWFVKKLQLAKPSPV
EECCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHH
RQHLENLQLNLIAAKSAQEELKELLQSGSLPKFLYEELFASYQARIANAEEELRGLYNQR
HHHHHHCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LTQKLSQFENQAYLEGLRHRLFLAEKSAINEAILKGLISDETARPYLQELNQKILALRDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PNPPLIIVRHIFLFGQAVSLPANAFTGLVNTLILLLLVATVVALVTRWLRIPYVIGLVL
CCCCEEHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLLIPKQILSDAIGLNPEVILNLFLPILIFEAAINTDISRLRSTIKPIALLAGPGVLLA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ATITAFFLKVSLDLAWLTACAVGVILTITDTVSVIAAFRTVPVPGRLATIVEGESLFNDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHCC
IALVLLNIVTTIHLQGSFSVGEGVEQILIAFVGGGLLGLGLGYLCIGLFRQLDDPLSNIL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH
LTVAVSLGTFQIGQALGVSSAIAVLIAGLLIGNVALRECSGSVTITLLNFWEYAGFGVNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHH
FIFLFVGIEVAPLSLLQTIPAALLAVVAYQVGRICSIYPLLSVLKFFDRPLPLRWQHVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
FGNVKGSLSMALALGLPLTLQGRSQVITLVFSTVLVSLIGQGLSLPWFVKKLQLAKPSPV
EECCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHH
RQHLENLQLNLIAAKSAQEELKELLQSGSLPKFLYEELFASYQARIANAEEELRGLYNQR
HHHHHHCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LTQKLSQFENQAYLEGLRHRLFLAEKSAINEAILKGLISDETARPYLQELNQKILALRDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]