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The map label for this gene is wzb [C]

Identifier: 170077594

GI number: 170077594

Start: 1001397

End: 1001870

Strand: Direct

Name: wzb [C]

Synonym: SYNPCC7002_A0973

Alternate gene names: 170077594

Gene position: 1001397-1001870 (Clockwise)

Preceding gene: 170077592

Following gene: 170077595

Centisome position: 33.29

GC content: 48.95

Gene sequence:

>474_bases
ATGGCCTATAAATTATTATTCGTTTGCCTCGGTAACATCTGCCGTTCCCCCTCCGCCGAAAATATTATGCGGCATCTTTT
GGAGCAAGAAGGTTTAAGCAATAAAATTCTCTGCGATTCGGCCGGGACTTCTAGCTATCACATAGGAGCCGCCCCAGACC
GACGGATGCAGGCAGCGGCCCAAAAGCGCGATATTCGTCTGATGGGTAGCGCCCGGCAATTTTCCCGCGCTGATTTTGAA
GCATTTGACCTGATCCTGGCAATGGATCGCGCTAATTATCGTGACATTTTGTCCCTAGACCGGGCGGATATCTATGGCGA
AAAAGTTAAAATGATGTGTGACTACGCCACGAATTTTCCCGATAGCGAAGTGCCAGATCCCTACTACGGCGGCCAATCGG
GTTTTGACTATGTGATTGATTTGCTCCTCGATGCCTGCCAAGGACTCCTCACAGAAATTAAACAGGAAATGTGA

Upstream 100 bases:

>100_bases
GGGAGATGGCCCATTTGTCATGGGGAATTTGTGCTTTTCCGGGAAGGAATTTGGGGTACACTGCAAAATTGCGATCGCCC
CTTAGCTAAAAAAAATTGAG

Downstream 100 bases:

>100_bases
TGGTGTAGGCAGTTTATTTTCTCGGTCACACCATGTTTATCCGCAATGCAACGGCGATCGCCTTATTGGGCCTCTTTTGG
TTCCAGGGGGCAGCTAGTAA

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MAYKLLFVCLGNICRSPSAENIMRHLLEQEGLSNKILCDSAGTSSYHIGAAPDRRMQAAAQKRDIRLMGSARQFSRADFE
AFDLILAMDRANYRDILSLDRADIYGEKVKMMCDYATNFPDSEVPDPYYGGQSGFDYVIDLLLDACQGLLTEIKQEM

Sequences:

>Translated_157_residues
MAYKLLFVCLGNICRSPSAENIMRHLLEQEGLSNKILCDSAGTSSYHIGAAPDRRMQAAAQKRDIRLMGSARQFSRADFE
AFDLILAMDRANYRDILSLDRADIYGEKVKMMCDYATNFPDSEVPDPYYGGQSGFDYVIDLLLDACQGLLTEIKQEM
>Mature_156_residues
AYKLLFVCLGNICRSPSAENIMRHLLEQEGLSNKILCDSAGTSSYHIGAAPDRRMQAAAQKRDIRLMGSARQFSRADFEA
FDLILAMDRANYRDILSLDRADIYGEKVKMMCDYATNFPDSEVPDPYYGGQSGFDYVIDLLLDACQGLLTEIKQEM

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=149, Percent_Identity=38.255033557047, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI6005988, Length=149, Percent_Identity=34.8993288590604, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI96304457, Length=76, Percent_Identity=44.7368421052632, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=138, Percent_Identity=34.7826086956522, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI78711846, Length=156, Percent_Identity=32.0512820512821, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI78706770, Length=160, Percent_Identity=35.625, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI78706772, Length=160, Percent_Identity=35.625, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI78706766, Length=155, Percent_Identity=33.5483870967742, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706768, Length=155, Percent_Identity=33.5483870967742, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706764, Length=131, Percent_Identity=35.1145038167939, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24648069, Length=94, Percent_Identity=38.2978723404255, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17666; Mature: 17535

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKLLFVCLGNICRSPSAENIMRHLLEQEGLSNKILCDSAGTSSYHIGAAPDRRMQAAA
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEECCCCCHHHHHHHH
QKRDIRLMGSARQFSRADFEAFDLILAMDRANYRDILSLDRADIYGEKVKMMCDYATNFP
HHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSEVPDPYYGGQSGFDYVIDLLLDACQGLLTEIKQEM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYKLLFVCLGNICRSPSAENIMRHLLEQEGLSNKILCDSAGTSSYHIGAAPDRRMQAAA
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEECCCCCHHHHHHHH
QKRDIRLMGSARQFSRADFEAFDLILAMDRANYRDILSLDRADIYGEKVKMMCDYATNFP
HHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSEVPDPYYGGQSGFDYVIDLLLDACQGLLTEIKQEM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]