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The map label for this gene is yeiG [C]

Identifier: 170077491

GI number: 170077491

Start: 898623

End: 899468

Strand: Direct

Name: yeiG [C]

Synonym: SYNPCC7002_A0869

Alternate gene names: 170077491

Gene position: 898623-899468 (Clockwise)

Preceding gene: 170077490

Following gene: 170077492

Centisome position: 29.87

GC content: 50.12

Gene sequence:

>846_bases
ATGACAAACCTTGTTTTAACGAAAGAAACCCTCTGTTTTGGCGGCAAAGTGCAGTATTACCAGCACGATTCTGAGGCGTG
CGGTGTACCGATGAATTTTTCGGTATTTGTGCCGCCCCAAGCCGAAACTCGACCCGTACCAACCCTCTATTATTTATCAG
GTTTGACCTGTACTGAGGAAAATTTCACCACGAAGGCGGGCGCTCAAAAATATGCCGCAGACTATGGCTTAATGCTCGTC
GCCCCCGATACTAGCCCTCGCAATACGGGCATCGCCGACGAGGATAAAGATTGGGATCTTGGCAGTGGCGCCGGTTTCTA
TGTGGATGCAACCCAACAGCCCTGGGCCAACCATTATCAAATGTACAGTTACATCACCGAGGAACTGCCCAAACTCATCG
AAGCGAACTTTTCCGTGACGGCGAAACGGGGGATTTTTGGCCATTCCATGGGGGGTCATGGAGCTTTAATTTGTGCCCTC
CGGCAGCCTGATTTCTACCAGTCGGTGTCTGCCTTTGCGCCGATTGTTGCGCCGAGCCAGTGCCCCTGGGGAGAAAAAGC
GTTTACTGCTTATCTGGGCACGGATAAAACCCTCTGGGAAAATTATGATGCGACGGCTCTCTTACAAAAAAATGGCCCTT
TAAAGTACCCAATCCTGGTGGATCAAGGCAGCGCCGATGGTTTTTTGGAGAAACAATTACTGACAGAAAAATTGGCGATC
GCCTGTGAAAAAGTCGGTCAACCCCTCACCCTCCGCTACCAAGACGGCTATGACCACAGCTATTTTTTCATTGCCACTTT
TATGCTTGACCATGTCCGACATCACGCCCAATTCCTGATTGGCTAA

Upstream 100 bases:

>100_bases
TGCACGCCGGAGAATCTATCCGCAGCGTGGTCACCTTTTAGATCCTCAAAATTGGTAGGGGTTTACCATGGTAAGCCCCC
ATAGCACGATCAAATTAACG

Downstream 100 bases:

>100_bases
ATGTTTTCGCCGAACCTGTTCCATAATGGGAACATCAGTTTAGGTGTGAGCCAAGCGTTACAGAGATTATGATTGGGCAG
TTACTCGATGGCCGCTATCG

Product: putative esterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTNLVLTKETLCFGGKVQYYQHDSEACGVPMNFSVFVPPQAETRPVPTLYYLSGLTCTEENFTTKAGAQKYAADYGLMLV
APDTSPRNTGIADEDKDWDLGSGAGFYVDATQQPWANHYQMYSYITEELPKLIEANFSVTAKRGIFGHSMGGHGALICAL
RQPDFYQSVSAFAPIVAPSQCPWGEKAFTAYLGTDKTLWENYDATALLQKNGPLKYPILVDQGSADGFLEKQLLTEKLAI
ACEKVGQPLTLRYQDGYDHSYFFIATFMLDHVRHHAQFLIG

Sequences:

>Translated_281_residues
MTNLVLTKETLCFGGKVQYYQHDSEACGVPMNFSVFVPPQAETRPVPTLYYLSGLTCTEENFTTKAGAQKYAADYGLMLV
APDTSPRNTGIADEDKDWDLGSGAGFYVDATQQPWANHYQMYSYITEELPKLIEANFSVTAKRGIFGHSMGGHGALICAL
RQPDFYQSVSAFAPIVAPSQCPWGEKAFTAYLGTDKTLWENYDATALLQKNGPLKYPILVDQGSADGFLEKQLLTEKLAI
ACEKVGQPLTLRYQDGYDHSYFFIATFMLDHVRHHAQFLIG
>Mature_280_residues
TNLVLTKETLCFGGKVQYYQHDSEACGVPMNFSVFVPPQAETRPVPTLYYLSGLTCTEENFTTKAGAQKYAADYGLMLVA
PDTSPRNTGIADEDKDWDLGSGAGFYVDATQQPWANHYQMYSYITEELPKLIEANFSVTAKRGIFGHSMGGHGALICALR
QPDFYQSVSAFAPIVAPSQCPWGEKAFTAYLGTDKTLWENYDATALLQKNGPLKYPILVDQGSADGFLEKQLLTEKLAIA
CEKVGQPLTLRYQDGYDHSYFFIATFMLDHVRHHAQFLIG

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=270, Percent_Identity=56.6666666666667, Blast_Score=330, Evalue=1e-90,
Organism=Escherichia coli, GI1788477, Length=278, Percent_Identity=53.9568345323741, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1786551, Length=276, Percent_Identity=49.6376811594203, Blast_Score=295, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17510185, Length=279, Percent_Identity=47.6702508960573, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6322393, Length=296, Percent_Identity=39.8648648648649, Blast_Score=211, Evalue=9e-56,
Organism=Drosophila melanogaster, GI45551932, Length=272, Percent_Identity=52.9411764705882, Blast_Score=296, Evalue=7e-81,
Organism=Drosophila melanogaster, GI24648347, Length=272, Percent_Identity=52.9411764705882, Blast_Score=296, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31207; Mature: 31075

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLVLTKETLCFGGKVQYYQHDSEACGVPMNFSVFVPPQAETRPVPTLYYLSGLTCTEE
CCCEEEEHHHEEECCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCEECCC
NFTTKAGAQKYAADYGLMLVAPDTSPRNTGIADEDKDWDLGSGAGFYVDATQQPWANHYQ
CCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
MYSYITEELPKLIEANFSVTAKRGIFGHSMGGHGALICALRQPDFYQSVSAFAPIVAPSQ
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCC
CPWGEKAFTAYLGTDKTLWENYDATALLQKNGPLKYPILVDQGSADGFLEKQLLTEKLAI
CCCCCHHEEEEECCCCHHHCCCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
ACEKVGQPLTLRYQDGYDHSYFFIATFMLDHVRHHAQFLIG
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNLVLTKETLCFGGKVQYYQHDSEACGVPMNFSVFVPPQAETRPVPTLYYLSGLTCTEE
CCEEEEHHHEEECCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCEECCC
NFTTKAGAQKYAADYGLMLVAPDTSPRNTGIADEDKDWDLGSGAGFYVDATQQPWANHYQ
CCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
MYSYITEELPKLIEANFSVTAKRGIFGHSMGGHGALICALRQPDFYQSVSAFAPIVAPSQ
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCC
CPWGEKAFTAYLGTDKTLWENYDATALLQKNGPLKYPILVDQGSADGFLEKQLLTEKLAI
CCCCCHHEEEEECCCCHHHCCCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
ACEKVGQPLTLRYQDGYDHSYFFIATFMLDHVRHHAQFLIG
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]