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The map label for this gene is dxr [H]

Identifier: 170077440

GI number: 170077440

Start: 844063

End: 845241

Strand: Direct

Name: dxr [H]

Synonym: SYNPCC7002_A0818

Alternate gene names: 170077440

Gene position: 844063-845241 (Clockwise)

Preceding gene: 170077439

Following gene: 170077445

Centisome position: 28.06

GC content: 52.25

Gene sequence:

>1179_bases
ATGACCAACGCTAAAGCCATCTCTATCCTTGGTTCCACCGGATCAATCGGGACGCAAACCCTCGATATTGTGCGATCGCA
CCCCGATAAATTCCGCGTGGTGGGGATGGCCGCTGGGCGTAACATTCAACTGCTGGCCGAACAGGTGCGGGAGTTCCACC
CAGAGATTGTTGCCACCAGCCAGGAAAGCCTTTTACCCGAACTAAAATCTCTCCTTCAAGATTTAGAACACCAACCCCAA
ATCATCGCTGGCAAAGCGGCGATCGCCGAAGTGGCCCGTTATGGTGATGCCGAAAGCGTGGTAACGGGGATTGTGGGCTG
TGCTGGACTTTTACCGACCATTGCGGCGATCGAAGCCGGCAAAGACATTGCTCTTGCTAACAAAGAAACCCTGATCGCTG
GGGGGCCAGTGGTTTTACCCTTAATCGAAAAATATGGCGTGAAACTACTGCCCGCTGACTCCGAACATTCCGCGATCTTC
CAATGTCTCCAGGGGGTGCCTGAAGGAGGTTTAAAGCGGATTATTCTCACGGCCTCCGGGGGCGCTTTCCGGGATCTGCC
TGTGGAAAAATTGGCCACCGTCACTGTCAAAGATGCCCTGAAACATCCCAACTGGTCCATGGGGCAAAAAATTACCATCG
ACTCCGCTACCCTGATGAACAAGGGTCTAGAGGTGATCGAAGCCCATTATCTCTTTGGTAAAGATTACGACGACATCGAC
ATTGTGGTGCATCCCCAGAGCATCATCCACTCCCTAATCGAGCTGCAAGATACCTCGGTTTTAGCCCAGTTGGGTTGGCC
TGATATGCGCTTGCCCCTGCTCTATGCCCTCTCCTACCCCGAACGCATTCACACCGATTGGGAGCAATTTGACCTCGTGA
AGGCCGGCGATCTTACCTTCCGGGAACCGGATCACCATAAATATCCCTGCATGAATTTGGCCTATGCTGCGGGACGGGCC
GGGGGATCGATGCCAGCAGTTTTAAATGCAGCGAATGAGCAAGCTGTGGCCCTTTTCCTCGAAGAAAAAATTGAATTCCT
CGATATCCCTCGTCTCATCGAAAAGGTTTGCGATCGCCACCAAAACGACAACAAGACAAACCCGACCCTAGACGACATTT
TGCAGGCAGATCAATGGGCCAGACAAGCTGTTCTTGAATTACAGCCACAATTAGCTTAA

Upstream 100 bases:

>100_bases
GCGAGGAAATCCCAAAGGCGATCGCCCCTTAAGTCGTCCCCACGAAGCCCCGATTATGAGATGATTGTCTGCAACAAACG
GGTTCACGCAAGCAAGTATC

Downstream 100 bases:

>100_bases
GGCCAAATCAAATTCCTTAGTTAACAGCTTGCAGGAAGTCTTGGACGGTAAGAATGGAAGCGTCTCGAAAGGGATGGAGA
GCGAGTAAATCTTGATCGCC

Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Products: NA

Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTNAKAISILGSTGSIGTQTLDIVRSHPDKFRVVGMAAGRNIQLLAEQVREFHPEIVATSQESLLPELKSLLQDLEHQPQ
IIAGKAAIAEVARYGDAESVVTGIVGCAGLLPTIAAIEAGKDIALANKETLIAGGPVVLPLIEKYGVKLLPADSEHSAIF
QCLQGVPEGGLKRIILTASGGAFRDLPVEKLATVTVKDALKHPNWSMGQKITIDSATLMNKGLEVIEAHYLFGKDYDDID
IVVHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSYPERIHTDWEQFDLVKAGDLTFREPDHHKYPCMNLAYAAGRA
GGSMPAVLNAANEQAVALFLEEKIEFLDIPRLIEKVCDRHQNDNKTNPTLDDILQADQWARQAVLELQPQLA

Sequences:

>Translated_392_residues
MTNAKAISILGSTGSIGTQTLDIVRSHPDKFRVVGMAAGRNIQLLAEQVREFHPEIVATSQESLLPELKSLLQDLEHQPQ
IIAGKAAIAEVARYGDAESVVTGIVGCAGLLPTIAAIEAGKDIALANKETLIAGGPVVLPLIEKYGVKLLPADSEHSAIF
QCLQGVPEGGLKRIILTASGGAFRDLPVEKLATVTVKDALKHPNWSMGQKITIDSATLMNKGLEVIEAHYLFGKDYDDID
IVVHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSYPERIHTDWEQFDLVKAGDLTFREPDHHKYPCMNLAYAAGRA
GGSMPAVLNAANEQAVALFLEEKIEFLDIPRLIEKVCDRHQNDNKTNPTLDDILQADQWARQAVLELQPQLA
>Mature_391_residues
TNAKAISILGSTGSIGTQTLDIVRSHPDKFRVVGMAAGRNIQLLAEQVREFHPEIVATSQESLLPELKSLLQDLEHQPQI
IAGKAAIAEVARYGDAESVVTGIVGCAGLLPTIAAIEAGKDIALANKETLIAGGPVVLPLIEKYGVKLLPADSEHSAIFQ
CLQGVPEGGLKRIILTASGGAFRDLPVEKLATVTVKDALKHPNWSMGQKITIDSATLMNKGLEVIEAHYLFGKDYDDIDI
VVHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSYPERIHTDWEQFDLVKAGDLTFREPDHHKYPCMNLAYAAGRAG
GSMPAVLNAANEQAVALFLEEKIEFLDIPRLIEKVCDRHQNDNKTNPTLDDILQADQWARQAVLELQPQLA

Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) [H]

COG id: COG0743

COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DXR family [H]

Homologues:

Organism=Escherichia coli, GI1786369, Length=388, Percent_Identity=44.3298969072165, Blast_Score=331, Evalue=6e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003821
- InterPro:   IPR013644
- InterPro:   IPR013512
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom [H]

EC number: =1.1.1.267 [H]

Molecular weight: Translated: 42742; Mature: 42610

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAKAISILGSTGSIGTQTLDIVRSHPDKFRVVGMAAGRNIQLLAEQVREFHPEIVATS
CCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHEECC
QESLLPELKSLLQDLEHQPQIIAGKAAIAEVARYGDAESVVTGIVGCAGLLPTIAAIEAG
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
KDIALANKETLIAGGPVVLPLIEKYGVKLLPADSEHSAIFQCLQGVPEGGLKRIILTASG
CCEEECCCCEEEECCCHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECC
GAFRDLPVEKLATVTVKDALKHPNWSMGQKITIDSATLMNKGLEVIEAHYLFGKDYDDID
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCHHHHHHHHHCCCCCCCEE
IVVHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSYPERIHTDWEQFDLVKAGDLTF
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHCCCHHHHCEEEECCCCC
REPDHHKYPCMNLAYAAGRAGGSMPAVLNAANEQAVALFLEEKIEFLDIPRLIEKVCDRH
CCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
QNDNKTNPTLDDILQADQWARQAVLELQPQLA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TNAKAISILGSTGSIGTQTLDIVRSHPDKFRVVGMAAGRNIQLLAEQVREFHPEIVATS
CCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCHHEECC
QESLLPELKSLLQDLEHQPQIIAGKAAIAEVARYGDAESVVTGIVGCAGLLPTIAAIEAG
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
KDIALANKETLIAGGPVVLPLIEKYGVKLLPADSEHSAIFQCLQGVPEGGLKRIILTASG
CCEEECCCCEEEECCCHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECC
GAFRDLPVEKLATVTVKDALKHPNWSMGQKITIDSATLMNKGLEVIEAHYLFGKDYDDID
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCHHHHHHHHHCCCCCCCEE
IVVHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSYPERIHTDWEQFDLVKAGDLTF
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHCCCHHHHCEEEECCCCC
REPDHHKYPCMNLAYAAGRAGGSMPAVLNAANEQAVALFLEEKIEFLDIPRLIEKVCDRH
CCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
QNDNKTNPTLDDILQADQWARQAVLELQPQLA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]