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The map label for this gene is gdhA [H]

Identifier: 170077396

GI number: 170077396

Start: 802598

End: 803893

Strand: Direct

Name: gdhA [H]

Synonym: SYNPCC7002_A0773

Alternate gene names: 170077396

Gene position: 802598-803893 (Clockwise)

Preceding gene: 170077388

Following gene: 170077400

Centisome position: 26.68

GC content: 51.0

Gene sequence:

>1296_bases
ATGACGGTAAATTCTCTCCTGAGCGATGCTAGCCTACGCCTCGAAAAAGCGCTCCACCACGTCAACATCTCTGAAGATGC
CAGCGAACGCTTGAAATATCCCAAAATGAGCCTGAGCGTTTCTATTCCCGTGCGCCTCGATGATGGTTCTTTGAAAATCT
TCCGGGGGTATCGGGTGCGGTATGACGACACTAGGGGGCCGGGTAAAGGAGGCGTGCGGTATCATCCCAACGTTTCCTTA
GACGAAGTACAATCCCTGGCCTTTTGGATGACCTTCAAATGTGCCTTGCTAGATCTGCCCTTTGGGGGAGCCAAGGGGGG
CATTACCGTTGATGCCAAAAGCCTTTCTAAAGCCGAACTAGAACGTTTGAGCCGGGGTTACATCGAGGCGATCGCCGATG
CCATTGGCCCCGACACAGACATTTTGGCACCGGATGTCTATACCAATGCCATGGTGATGGGTTGGATGATGGATCATTAC
AGCATTATTCAACGGAAAATTTTGCCGGGGGTCGTAACGGGCAAGCCCTTGGGCATGGGAGGAAGTCAAGGACGCAATAC
CGCGACGGCCAGTGGTGCCTTTGATGTAATTAAAACCATCTGCAAAAAACTAGAATATGTACCCGAAAAAACCACCGTTG
CGGTGCAAGGGTTTGGCAATGCCGGAGCAGAACTAGCCCAACAACTAGCCTGCGCTGGCTACCGTGTTGTCGCCGTTAGT
GATTCCCGTGGGGGGATCTATGCAGAACAGGGCTTAGATATTCCGAGCATCCGCCAGTACAAGTCAGAAAGTCGGAATAT
GGCTGCTGTTTATTGTGAAAAATCCGTTTGCAATATTGTTGAACACCAAACGATCACCAATGAACAACTTTTGACCTTAG
ATGTGGACATTCTGATTCCGGCAGCCCTGGAAAATCAAATTACGGCGGACAATGCCCATCAAGTGCAAGCCAAATTAATT
TTTGAAGTGGCCAACGGCCCCATTAGCTCGGCTGCGGATGTCATCCTAGAAGAAAAAGGAATTATGGTGGTGCCGGATAT
TCTCACCAATGCTGGGGGAGTCACGGTGAGTTATTTTGAGTGGGTGCAAAATCGCAGTGGCTTTTATTGGCCAGCGACGG
ACATTCGTGATCAGCTGAAGACGCGTATGGTTACAGCCACAAACCAGGTGTGGCACATTGCCCAAACGCGACAGATTTCA
ATGCGGACTGCGGCCTATGTCCAGGCCCTGATGCGCCTCGGTGAGGCCCTAGATGCGAAGGGGACACGCACTTATTTTTC
AGGCAGTTCGGCCTAG

Upstream 100 bases:

>100_bases
CACCAGCAGATGTAACGATTTCCCCGTGATTCATGTTCCCAACCTCACAAGCCAAAGTCACCGTGATTTAATACCCCTTA
TTCGGCTTAAACCATGAACC

Downstream 100 bases:

>100_bases
GGGAGAATTCTTTCGATTTACGCCCTAGGGACGGCAAAATCAGCAGGGTTCAACCAACGGCAGATCTCTGTTTTCAATCC
CTTTAGATCCTTTGATAGGC

Product: glutamate/leucine/phenylalanine/valine dehydrogenase

Products: NA

Alternate protein names: NADP-GDH [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTVNSLLSDASLRLEKALHHVNISEDASERLKYPKMSLSVSIPVRLDDGSLKIFRGYRVRYDDTRGPGKGGVRYHPNVSL
DEVQSLAFWMTFKCALLDLPFGGAKGGITVDAKSLSKAELERLSRGYIEAIADAIGPDTDILAPDVYTNAMVMGWMMDHY
SIIQRKILPGVVTGKPLGMGGSQGRNTATASGAFDVIKTICKKLEYVPEKTTVAVQGFGNAGAELAQQLACAGYRVVAVS
DSRGGIYAEQGLDIPSIRQYKSESRNMAAVYCEKSVCNIVEHQTITNEQLLTLDVDILIPAALENQITADNAHQVQAKLI
FEVANGPISSAADVILEEKGIMVVPDILTNAGGVTVSYFEWVQNRSGFYWPATDIRDQLKTRMVTATNQVWHIAQTRQIS
MRTAAYVQALMRLGEALDAKGTRTYFSGSSA

Sequences:

>Translated_431_residues
MTVNSLLSDASLRLEKALHHVNISEDASERLKYPKMSLSVSIPVRLDDGSLKIFRGYRVRYDDTRGPGKGGVRYHPNVSL
DEVQSLAFWMTFKCALLDLPFGGAKGGITVDAKSLSKAELERLSRGYIEAIADAIGPDTDILAPDVYTNAMVMGWMMDHY
SIIQRKILPGVVTGKPLGMGGSQGRNTATASGAFDVIKTICKKLEYVPEKTTVAVQGFGNAGAELAQQLACAGYRVVAVS
DSRGGIYAEQGLDIPSIRQYKSESRNMAAVYCEKSVCNIVEHQTITNEQLLTLDVDILIPAALENQITADNAHQVQAKLI
FEVANGPISSAADVILEEKGIMVVPDILTNAGGVTVSYFEWVQNRSGFYWPATDIRDQLKTRMVTATNQVWHIAQTRQIS
MRTAAYVQALMRLGEALDAKGTRTYFSGSSA
>Mature_430_residues
TVNSLLSDASLRLEKALHHVNISEDASERLKYPKMSLSVSIPVRLDDGSLKIFRGYRVRYDDTRGPGKGGVRYHPNVSLD
EVQSLAFWMTFKCALLDLPFGGAKGGITVDAKSLSKAELERLSRGYIEAIADAIGPDTDILAPDVYTNAMVMGWMMDHYS
IIQRKILPGVVTGKPLGMGGSQGRNTATASGAFDVIKTICKKLEYVPEKTTVAVQGFGNAGAELAQQLACAGYRVVAVSD
SRGGIYAEQGLDIPSIRQYKSESRNMAAVYCEKSVCNIVEHQTITNEQLLTLDVDILIPAALENQITADNAHQVQAKLIF
EVANGPISSAADVILEEKGIMVVPDILTNAGGVTVSYFEWVQNRSGFYWPATDIRDQLKTRMVTATNQVWHIAQTRQISM
RTAAYVQALMRLGEALDAKGTRTYFSGSSA

Specific function: Unknown

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

Organism=Homo sapiens, GI31377775, Length=344, Percent_Identity=39.8255813953488, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI4885281, Length=345, Percent_Identity=40.5797101449275, Blast_Score=247, Evalue=1e-65,
Organism=Escherichia coli, GI1788059, Length=400, Percent_Identity=29.75, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17544676, Length=367, Percent_Identity=33.5149863760218, Blast_Score=216, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6319256, Length=396, Percent_Identity=29.7979797979798, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324951, Length=394, Percent_Identity=30.4568527918782, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI45553475, Length=340, Percent_Identity=37.3529411764706, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI45549226, Length=340, Percent_Identity=37.3529411764706, Blast_Score=238, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24649283, Length=341, Percent_Identity=36.950146627566, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24649460, Length=288, Percent_Identity=38.1944444444444, Blast_Score=198, Evalue=7e-51,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 9362 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR014362
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.4 [H]

Molecular weight: Translated: 46966; Mature: 46835

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVNSLLSDASLRLEKALHHVNISEDASERLKYPKMSLSVSIPVRLDDGSLKIFRGYRVR
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEEECCCCEEEEEEEEEE
YDDTRGPGKGGVRYHPNVSLDEVQSLAFWMTFKCALLDLPFGGAKGGITVDAKSLSKAEL
ECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEHHHHHHHHH
ERLSRGYIEAIADAIGPDTDILAPDVYTNAMVMGWMMDHYSIIQRKILPGVVTGKPLGMG
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GSQGRNTATASGAFDVIKTICKKLEYVPEKTTVAVQGFGNAGAELAQQLACAGYRVVAVS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEE
DSRGGIYAEQGLDIPSIRQYKSESRNMAAVYCEKSVCNIVEHQTITNEQLLTLDVDILIP
CCCCCEEHHCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCEEEEEEEEEEEC
AALENQITADNAHQVQAKLIFEVANGPISSAADVILEEKGIMVVPDILTNAGGVTVSYFE
HHHCCCCCCCCHHHHHHEEEEEECCCCCCHHHHHHEECCCCEEECHHHCCCCCCEEHHHH
WVQNRSGFYWPATDIRDQLKTRMVTATNQVWHIAQTRQISMRTAAYVQALMRLGEALDAK
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
GTRTYFSGSSA
CCEEECCCCCC
>Mature Secondary Structure 
TVNSLLSDASLRLEKALHHVNISEDASERLKYPKMSLSVSIPVRLDDGSLKIFRGYRVR
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEEEEECCCCEEEEEEEEEE
YDDTRGPGKGGVRYHPNVSLDEVQSLAFWMTFKCALLDLPFGGAKGGITVDAKSLSKAEL
ECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEHHHHHHHHH
ERLSRGYIEAIADAIGPDTDILAPDVYTNAMVMGWMMDHYSIIQRKILPGVVTGKPLGMG
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GSQGRNTATASGAFDVIKTICKKLEYVPEKTTVAVQGFGNAGAELAQQLACAGYRVVAVS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEE
DSRGGIYAEQGLDIPSIRQYKSESRNMAAVYCEKSVCNIVEHQTITNEQLLTLDVDILIP
CCCCCEEHHCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCCEEEEEEEEEEEC
AALENQITADNAHQVQAKLIFEVANGPISSAADVILEEKGIMVVPDILTNAGGVTVSYFE
HHHCCCCCCCCHHHHHHEEEEEECCCCCCHHHHHHEECCCCEEECHHHCCCCCCEEHHHH
WVQNRSGFYWPATDIRDQLKTRMVTATNQVWHIAQTRQISMRTAAYVQALMRLGEALDAK
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
GTRTYFSGSSA
CCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7787182; 8590279; 8905231 [H]