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The map label for this gene is ruvC [H]

Identifier: 170077253

GI number: 170077253

Start: 660524

End: 661006

Strand: Reverse

Name: ruvC [H]

Synonym: SYNPCC7002_A0630

Alternate gene names: 170077253

Gene position: 661006-660524 (Counterclockwise)

Preceding gene: 170077254

Following gene: 170077252

Centisome position: 21.97

GC content: 49.9

Gene sequence:

>483_bases
ATGAAGCGTTGGCTTGGCATTGATCCTGGTTTAGCGATTATTGGCTGGGCGGTTCTCGAAGAACAGGGGCAAACGCTGCC
ACAAATTCTTGATTACGGCATTATCGAAACAGCCAAAGATTTATCGACGCCCCAACGACTCCTAGAGATTGAACAGGACT
ACACAGAAATTTTGGGGGAATTTCACCCAGAGGCGATCGCCATCGAGATGCCCTTCTTTAGCCGTCAGATCAAAGCCGCA
GGAGGCGTGTTGCAGGGCCTAGGCATTTTAAACTTGGTTAGCCTGCGAGAATTAAACATCGAACCGATTTATCTGCACCA
ATCCAGTTGGAAATGCCACATTGGTAATGCAAAGGCCGATAAGCGGGAAGTGGCGACCCTCGTGCAGTCGATTTTTGGGA
TGGAGACGATGCCTATCGATGATAGTGTCGACGCCATTGCGATCGCCTATGCCGCCGCCTGTGGCTTACGGAATAACATT
TGA

Upstream 100 bases:

>100_bases
GAACTTTGAGGGTTTTGGAGTTTCAACCGTACTGGAAGTGTGCTTTGAATGTCATGCTAGATTTGTAACTGAATAAATAT
CTTGTAAAAATTGTTTTGCC

Downstream 100 bases:

>100_bases
CCCTGGTAGCTTTTTAGGGTCATTTTTTTGGTAGACTTTCTAGGATAGCCTCAAAATCATAAAATACTAACTAATAATAA
AATTAAACATGAATAAAATT

Product: Holliday juction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKRWLGIDPGLAIIGWAVLEEQGQTLPQILDYGIIETAKDLSTPQRLLEIEQDYTEILGEFHPEAIAIEMPFFSRQIKAA
GGVLQGLGILNLVSLRELNIEPIYLHQSSWKCHIGNAKADKREVATLVQSIFGMETMPIDDSVDAIAIAYAAACGLRNNI

Sequences:

>Translated_160_residues
MKRWLGIDPGLAIIGWAVLEEQGQTLPQILDYGIIETAKDLSTPQRLLEIEQDYTEILGEFHPEAIAIEMPFFSRQIKAA
GGVLQGLGILNLVSLRELNIEPIYLHQSSWKCHIGNAKADKREVATLVQSIFGMETMPIDDSVDAIAIAYAAACGLRNNI
>Mature_160_residues
MKRWLGIDPGLAIIGWAVLEEQGQTLPQILDYGIIETAKDLSTPQRLLEIEQDYTEILGEFHPEAIAIEMPFFSRQIKAA
GGVLQGLGILNLVSLRELNIEPIYLHQSSWKCHIGNAKADKREVATLVQSIFGMETMPIDDSVDAIAIAYAAACGLRNNI

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 17660; Mature: 17660

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRWLGIDPGLAIIGWAVLEEQGQTLPQILDYGIIETAKDLSTPQRLLEIEQDYTEILGE
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FHPEAIAIEMPFFSRQIKAAGGVLQGLGILNLVSLRELNIEPIYLHQSSWKCHIGNAKAD
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCH
KREVATLVQSIFGMETMPIDDSVDAIAIAYAAACGLRNNI
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRWLGIDPGLAIIGWAVLEEQGQTLPQILDYGIIETAKDLSTPQRLLEIEQDYTEILGE
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FHPEAIAIEMPFFSRQIKAAGGVLQGLGILNLVSLRELNIEPIYLHQSSWKCHIGNAKAD
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCH
KREVATLVQSIFGMETMPIDDSVDAIAIAYAAACGLRNNI
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]