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The map label for this gene is rdgB [C]

Identifier: 170077226

GI number: 170077226

Start: 631344

End: 631919

Strand: Reverse

Name: rdgB [C]

Synonym: SYNPCC7002_A0601

Alternate gene names: 170077226

Gene position: 631919-631344 (Counterclockwise)

Preceding gene: 170077227

Following gene: 170077225

Centisome position: 21.01

GC content: 55.38

Gene sequence:

>576_bases
ATGCCCGTCCTTGTCGTCGCCACCGGAAACCCCGGTAAATTACAGGAAATGCAAGCCTATCTCCAGGATTTGCCCTGGGA
ATTGCAGCTCAAGCCCCCGGAACTCAACATCGAAGAAACAGGCACAACGTTTCTCGAAAATGCAGCTCTCAAGGCCTCTC
AGGTGGCAAAGGCCCTCAACCAATGGGCGATCGCCGATGATTCTGGTTTAGCCGTCGAAGCCCTCAACGGTGCCCCTGGT
CTGTATTCAGCCCGCTACGGCACCACCGACCAAGAACGCATTGAACGTCTGTTAACGGAACTGGGCAACAACCCCAATCG
CCGCGCGAAATTTATCTGTGCAGTGGCGATCGCCAAACCAGACGGTACCATTGCCGCCCAAGTGCAAGGAGACTGTCCCG
GAGAAATCCTCCCGGAACTGCGGGGGAGAGGGGGCTTTGGCTATGACCCCATTTTTTATGTGCCAGAATATCAACAGACC
TTTGCGGAAATGTCAGCGGCGCTCAAACATAACGTCAGTCACCGGGGCCAAGCCTTTGCACTGCTGTTGCCGCGTCTTGC
CACACTCCTCGATTAA

Upstream 100 bases:

>100_bases
CCTTGGTCGTCTTTTTTTTAGCAAATTTCCTTAAAATAGGAGTCGCTGCCCGGTACTCCCGGTTAACTTTTTTAATTTCT
CATCCAGATATTTAACGCCC

Downstream 100 bases:

>100_bases
CGATGCCTGCTCCCCCAACCCCAGAAGATCGCAACCCTGAAGCGTCCCTCCGAGAACTCCTTACCCTTGGGAGCATGTTT
CTCTGTGCGATCGCCCTCTT

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MPVLVVATGNPGKLQEMQAYLQDLPWELQLKPPELNIEETGTTFLENAALKASQVAKALNQWAIADDSGLAVEALNGAPG
LYSARYGTTDQERIERLLTELGNNPNRRAKFICAVAIAKPDGTIAAQVQGDCPGEILPELRGRGGFGYDPIFYVPEYQQT
FAEMSAALKHNVSHRGQAFALLLPRLATLLD

Sequences:

>Translated_191_residues
MPVLVVATGNPGKLQEMQAYLQDLPWELQLKPPELNIEETGTTFLENAALKASQVAKALNQWAIADDSGLAVEALNGAPG
LYSARYGTTDQERIERLLTELGNNPNRRAKFICAVAIAKPDGTIAAQVQGDCPGEILPELRGRGGFGYDPIFYVPEYQQT
FAEMSAALKHNVSHRGQAFALLLPRLATLLD
>Mature_190_residues
PVLVVATGNPGKLQEMQAYLQDLPWELQLKPPELNIEETGTTFLENAALKASQVAKALNQWAIADDSGLAVEALNGAPGL
YSARYGTTDQERIERLLTELGNNPNRRAKFICAVAIAKPDGTIAAQVQGDCPGEILPELRGRGGFGYDPIFYVPEYQQTF
AEMSAALKHNVSHRGQAFALLLPRLATLLD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=45.1282051282051, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17556833, Length=176, Percent_Identity=28.9772727272727, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322529, Length=186, Percent_Identity=32.258064516129, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920712, Length=183, Percent_Identity=32.2404371584699, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20748; Mature: 20617

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLVVATGNPGKLQEMQAYLQDLPWELQLKPPELNIEETGTTFLENAALKASQVAKALN
CCEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHH
QWAIADDSGLAVEALNGAPGLYSARYGTTDQERIERLLTELGNNPNRRAKFICAVAIAKP
HCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECC
DGTIAAQVQGDCPGEILPELRGRGGFGYDPIFYVPEYQQTFAEMSAALKHNVSHRGQAFA
CCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCHHH
LLLPRLATLLD
HHHHHHHHHCC
>Mature Secondary Structure 
PVLVVATGNPGKLQEMQAYLQDLPWELQLKPPELNIEETGTTFLENAALKASQVAKALN
CEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHH
QWAIADDSGLAVEALNGAPGLYSARYGTTDQERIERLLTELGNNPNRRAKFICAVAIAKP
HCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECC
DGTIAAQVQGDCPGEILPELRGRGGFGYDPIFYVPEYQQTFAEMSAALKHNVSHRGQAFA
CCCEEEEECCCCCHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCHHH
LLLPRLATLLD
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]