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The map label for this gene is napA [H]

Identifier: 170077202

GI number: 170077202

Start: 601692

End: 603062

Strand: Direct

Name: napA [H]

Synonym: SYNPCC7002_A0577

Alternate gene names: 170077202

Gene position: 601692-603062 (Clockwise)

Preceding gene: 170077200

Following gene: 170077203

Centisome position: 20.0

GC content: 51.93

Gene sequence:

>1371_bases
ATGCCGTATTTTCAATCGTTCCTTCTCAATGCGCCCCCCGCTAGTGAAGCAGCGGAACCCTCCATGATTCTGGCTGCGGT
GCTACTGAGCCTTGTGGTCATCTACTTTGCGAGTAAAGTGGGCGGAGAGCTTTGTTCCCGCATCAATCTCCCCCCAGTAC
TGGGCGAATTAGTCGGCGGAGTATTGGTGGGCGTATCTGCCCTGAGTTTACTGGTCTTTCCAGAAGGGGGCATCGAAGCG
TCCCAATCACTACTGATGCAATTTCTGCAAAATACAGCCGGTTTAAGTCCAGAGGCAGCCCCGGCAGTGTTTGCCACCCA
AAGCGAAGTAATTTCTGTCCTCGCAGAACTAGGGGTCATTATCCTTCTGTTTGAAATTGGTCTTGAATCGGATCTACAAG
AATTGATTAAAGTTGGCCCCCAAGCCGCCATTGTCGCCGTGGTTGGGGTTGTGGCACCTTTTGCTGCAGGGACAGCAGGT
TTAGTCTTTTTATTCCATCTCAGTACAGTGCCAGCGATTTTTGCGGGGGCAGCCCTCACGGCAACCAGTATCGGGATTAC
CGCGAAGGTGCTAGCAGAATTGGGTCAACTGACCACCAAAGAAGGACAAATTATCATTGGCGCGGCTGTACTCGATGATG
TCCTCGGCATTATTGTCCTCGCTGTGGTTGCAAGCTTGGCGAAAACAGGAGAAGTGCAGGTTGTCAGCACTATCTGGCTC
ATTGTGAGTGCTGGGGCGTTTCTCATTGGTGCGATTATTGTCGGTCGCCTCCTGAGTCCTTTATTTGTCAGTTTGGTGGA
TGGGATGAAAACCAGAGGCCAATTGTTAACCGTATCCGTTGTTTTTGCCTTTGTGCTGTCCTACATTGCGACGGTGATCC
AACTGGAAGCGATTCTTGGGGCCTTTGCGGCTGGACTGATTTTGGCGGAAACGGATAAACGGGGCGAACTAGAAGAACAA
GTATTGCCGGTGGCGGATTTGTTTGTGCCGATCTTTTTTGTGTGCGTCGGGGCAAAAACAGACCTCAGCGTCCTCAACCC
GGCGGTTCCGGCCAACCGTGAAGGATTAATTATTGCGGCCTTTTTGATCGTGGTCGCAATTGTCGGTAAGGTCATTACGG
GCTTTACCGTCTTCGGCCAAGACCAGTTGAACAAGTTGGCGATTGGGGTAGGCATGATTCCCCGGGGCGAAGTGGGCCTT
GTGTTTGCAGGGGTTGGTTCGGCCAGTGGCGCCCTCTCGGAATCGACGGAAGCGGCAATTATTATGATGGTCATCTTGAC
GACATTTATTGCACCGCCATTTTTGCGTTTGGTCTTTAAGGAACCCCAGGCGGCGATCGCCACTGGAGAGACGCCGGAGA
AGCTACAATAA

Upstream 100 bases:

>100_bases
AGGAAGCCTCTGGTTATTCTGCCCCGTTTTTTGACCGAAGCCAAACCTCCCCGGACAACTTTGGTCCCTACGCTTGTCGT
TACCTTGTAATCAAAAATTC

Downstream 100 bases:

>100_bases
TTCAGCCTTGGGCAACCATTGAAACATATCCTAAGCGACCCACGTCCCTTGGGAGAAGGTAGGAAGAGGTTTTATCTCTA
TCCACCGGAATTGTTCTATA

Product: Na/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MPYFQSFLLNAPPASEAAEPSMILAAVLLSLVVIYFASKVGGELCSRINLPPVLGELVGGVLVGVSALSLLVFPEGGIEA
SQSLLMQFLQNTAGLSPEAAPAVFATQSEVISVLAELGVIILLFEIGLESDLQELIKVGPQAAIVAVVGVVAPFAAGTAG
LVFLFHLSTVPAIFAGAALTATSIGITAKVLAELGQLTTKEGQIIIGAAVLDDVLGIIVLAVVASLAKTGEVQVVSTIWL
IVSAGAFLIGAIIVGRLLSPLFVSLVDGMKTRGQLLTVSVVFAFVLSYIATVIQLEAILGAFAAGLILAETDKRGELEEQ
VLPVADLFVPIFFVCVGAKTDLSVLNPAVPANREGLIIAAFLIVVAIVGKVITGFTVFGQDQLNKLAIGVGMIPRGEVGL
VFAGVGSASGALSESTEAAIIMMVILTTFIAPPFLRLVFKEPQAAIATGETPEKLQ

Sequences:

>Translated_456_residues
MPYFQSFLLNAPPASEAAEPSMILAAVLLSLVVIYFASKVGGELCSRINLPPVLGELVGGVLVGVSALSLLVFPEGGIEA
SQSLLMQFLQNTAGLSPEAAPAVFATQSEVISVLAELGVIILLFEIGLESDLQELIKVGPQAAIVAVVGVVAPFAAGTAG
LVFLFHLSTVPAIFAGAALTATSIGITAKVLAELGQLTTKEGQIIIGAAVLDDVLGIIVLAVVASLAKTGEVQVVSTIWL
IVSAGAFLIGAIIVGRLLSPLFVSLVDGMKTRGQLLTVSVVFAFVLSYIATVIQLEAILGAFAAGLILAETDKRGELEEQ
VLPVADLFVPIFFVCVGAKTDLSVLNPAVPANREGLIIAAFLIVVAIVGKVITGFTVFGQDQLNKLAIGVGMIPRGEVGL
VFAGVGSASGALSESTEAAIIMMVILTTFIAPPFLRLVFKEPQAAIATGETPEKLQ
>Mature_455_residues
PYFQSFLLNAPPASEAAEPSMILAAVLLSLVVIYFASKVGGELCSRINLPPVLGELVGGVLVGVSALSLLVFPEGGIEAS
QSLLMQFLQNTAGLSPEAAPAVFATQSEVISVLAELGVIILLFEIGLESDLQELIKVGPQAAIVAVVGVVAPFAAGTAGL
VFLFHLSTVPAIFAGAALTATSIGITAKVLAELGQLTTKEGQIIIGAAVLDDVLGIIVLAVVASLAKTGEVQVVSTIWLI
VSAGAFLIGAIIVGRLLSPLFVSLVDGMKTRGQLLTVSVVFAFVLSYIATVIQLEAILGAFAAGLILAETDKRGELEEQV
LPVADLFVPIFFVCVGAKTDLSVLNPAVPANREGLIIAAFLIVVAIVGKVITGFTVFGQDQLNKLAIGVGMIPRGEVGLV
FAGVGSASGALSESTEAAIIMMVILTTFIAPPFLRLVFKEPQAAIATGETPEKLQ

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=415, Percent_Identity=26.7469879518072, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786232, Length=247, Percent_Identity=27.5303643724696, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322367, Length=369, Percent_Identity=26.2872628726287, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46891; Mature: 46760

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCHHHHHHHHCCCHHEECCCCCCCCC
>Mature Secondary Structure 
PYFQSFLLNAPPASEAAEPSMILAAVLLSLVVIYFASKVGGELCSRINLPPVLGELVGG
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH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HHHHHHHHHHCCHHHHHHHHCCCHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]