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The map label for this gene is trm1 [H]

Identifier: 170077104

GI number: 170077104

Start: 508942

End: 510045

Strand: Direct

Name: trm1 [H]

Synonym: SYNPCC7002_A0478

Alternate gene names: 170077104

Gene position: 508942-510045 (Clockwise)

Preceding gene: 170077103

Following gene: 170077105

Centisome position: 16.92

GC content: 54.26

Gene sequence:

>1104_bases
GTGGTGCAACTGGTTGAAGAGCGGTCGATACAATTTCAGGTAGATGGGGGCTTCTACCGGGCCCACAGCCGCATTGTGCG
AGATTTAGGGGTATTAGCGGCGGCGGTCTATCGACAAAATCAAGGGCAATTGCGGGTTCTAGATGGCCTATCGGCAACGG
GGGTGCGATCGCTCCGGTACTACCAAGAAGCCCAAGCCGATTGGGTCTGGGCCAATGAAGGAAACCCAGATCTCTTGGAG
ACGTTGACCACGAATTTGCGGCGAATTCCCGCGGCCCAACGGTGCATTAGTGTGCTTTCTCTACGGCAGCTTTGTTTGGA
ACGGTCTTTAATGGGCGATCGCTATGATCTGGTTGATTTTGATGCCTTTGGCTCTGGGTCAGCCTTCGTCCAGGATGCCC
TCACCGTCACGACCCTGGACGGATTGATGTACCTGACTAGCACCGATGGTCGAACCTACAGTGGCCGAGAACCGCAACGG
GCCTTGCGGCAAGGGGCCTATGGGCGATCGCATCCTGCCGTCCAGGAACAGGGCCTACGGCTATTGCTAGGGAGCCTCGC
CCAACAGGCAGCCCAGCGCAATTTCGGCATTGAGCCAATTTTTTCGTTATTTTGGGGGGATACTTGCCGGATTATGGCCC
GTTTGACCCGTAAACCCATCCTCACGGAGACAAACTACGGCTTCCTCGGCTATTGTCACCACTGCGGCACCTATGGCCTA
CCGACATGGCGTAAACTGTCTCAGGCGACCTGTGCCCACGATGATTTGCCCTTAACCCTCAGTGGCCCGATGTGGTTAGG
CAAGCTGCACCACCCGGATTATTTACGGCAAATGTTAGCGATCGCCCAACGCTGGCACTGGCAGGATGTGGTCAAGGTTC
TAGAAACGATGGCCTTAGAAAATGATTTACCCCCCTATTTTTTCCCTTTAAAAGAGATTGGTGCCCGGGCCAAAATCGAT
CTGCCGAAATTAGATTCGCTACTGAATAGTCTCCAGGCGCAAGGTTTCCAAGCCAGTCGCACCCACATTAATCCCCAAGC
GCTGAAAACCGATGCGCCAATGGAAAAAATTAAGGCGATCGCCACCCAGTTAGGCGCATCTTAA

Upstream 100 bases:

>100_bases
TGTTGGTGGTGGGTAATGCTGCCGCCATGGATCCTCCCCTAAGCAGTCTGTTTGAGACGATTAAACCTGTTGACATCACC
ATCCCTGAGTAGGTGGCGTT

Downstream 100 bases:

>100_bases
ATTGTCGTTTAACCTTGTAATCTTTAACTCAGTGTCTGGAGGATGTCACCCAAACTTTATTTGTTGTGAAATGTCCAAAA
ACTATTGTTACTGAGCCCGT

Product: N2,N2-dimethylguanosine tRNA methyltransferase

Products: NA

Alternate protein names: tRNA 2,2-dimethylguanosine-26 methyltransferase; tRNA(guanine-26,N(2)-N(2)) methyltransferase; tRNA(m(2,2)G26)dimethyltransferase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MVQLVEERSIQFQVDGGFYRAHSRIVRDLGVLAAAVYRQNQGQLRVLDGLSATGVRSLRYYQEAQADWVWANEGNPDLLE
TLTTNLRRIPAAQRCISVLSLRQLCLERSLMGDRYDLVDFDAFGSGSAFVQDALTVTTLDGLMYLTSTDGRTYSGREPQR
ALRQGAYGRSHPAVQEQGLRLLLGSLAQQAAQRNFGIEPIFSLFWGDTCRIMARLTRKPILTETNYGFLGYCHHCGTYGL
PTWRKLSQATCAHDDLPLTLSGPMWLGKLHHPDYLRQMLAIAQRWHWQDVVKVLETMALENDLPPYFFPLKEIGARAKID
LPKLDSLLNSLQAQGFQASRTHINPQALKTDAPMEKIKAIATQLGAS

Sequences:

>Translated_367_residues
MVQLVEERSIQFQVDGGFYRAHSRIVRDLGVLAAAVYRQNQGQLRVLDGLSATGVRSLRYYQEAQADWVWANEGNPDLLE
TLTTNLRRIPAAQRCISVLSLRQLCLERSLMGDRYDLVDFDAFGSGSAFVQDALTVTTLDGLMYLTSTDGRTYSGREPQR
ALRQGAYGRSHPAVQEQGLRLLLGSLAQQAAQRNFGIEPIFSLFWGDTCRIMARLTRKPILTETNYGFLGYCHHCGTYGL
PTWRKLSQATCAHDDLPLTLSGPMWLGKLHHPDYLRQMLAIAQRWHWQDVVKVLETMALENDLPPYFFPLKEIGARAKID
LPKLDSLLNSLQAQGFQASRTHINPQALKTDAPMEKIKAIATQLGAS
>Mature_367_residues
MVQLVEERSIQFQVDGGFYRAHSRIVRDLGVLAAAVYRQNQGQLRVLDGLSATGVRSLRYYQEAQADWVWANEGNPDLLE
TLTTNLRRIPAAQRCISVLSLRQLCLERSLMGDRYDLVDFDAFGSGSAFVQDALTVTTLDGLMYLTSTDGRTYSGREPQR
ALRQGAYGRSHPAVQEQGLRLLLGSLAQQAAQRNFGIEPIFSLFWGDTCRIMARLTRKPILTETNYGFLGYCHHCGTYGL
PTWRKLSQATCAHDDLPLTLSGPMWLGKLHHPDYLRQMLAIAQRWHWQDVVKVLETMALENDLPPYFFPLKEIGARAKID
LPKLDSLLNSLQAQGFQASRTHINPQALKTDAPMEKIKAIATQLGAS

Specific function: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups [H]

COG id: COG1867

COG function: function code J; N2,N2-dimethylguanosine tRNA methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRM1 family [H]

Homologues:

Organism=Homo sapiens, GI8923219, Length=348, Percent_Identity=25.5747126436782, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI209862871, Length=348, Percent_Identity=25.5747126436782, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI216548445, Length=330, Percent_Identity=25.7575757575758, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564890, Length=349, Percent_Identity=24.6418338108883, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320325, Length=362, Percent_Identity=27.9005524861878, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19921190, Length=434, Percent_Identity=23.2718894009217, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022923
- InterPro:   IPR002905 [H]

Pfam domain/function: PF02005 TRM [H]

EC number: =2.1.1.32 [H]

Molecular weight: Translated: 41209; Mature: 41209

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLVEERSIQFQVDGGFYRAHSRIVRDLGVLAAAVYRQNQGQLRVLDGLSATGVRSLRY
CCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
YQEAQADWVWANEGNPDLLETLTTNLRRIPAAQRCISVLSLRQLCLERSLMGDRYDLVDF
HHHHCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
DAFGSGSAFVQDALTVTTLDGLMYLTSTDGRTYSGREPQRALRQGAYGRSHPAVQEQGLR
CCCCCCCHHHHHHHHHEECCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHH
LLLGSLAQQAAQRNFGIEPIFSLFWGDTCRIMARLTRKPILTETNYGFLGYCHHCGTYGL
HHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCEECCCCCHHHHHHHCCCCCC
PTWRKLSQATCAHDDLPLTLSGPMWLGKLHHPDYLRQMLAIAQRWHWQDVVKVLETMALE
CHHHHHHHHHCCCCCCCEEECCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NDLPPYFFPLKEIGARAKIDLPKLDSLLNSLQAQGFQASRTHINPQALKTDAPMEKIKAI
CCCCCCEECHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCHHHHCCCCCHHHHHHH
ATQLGAS
HHHHCCC
>Mature Secondary Structure
MVQLVEERSIQFQVDGGFYRAHSRIVRDLGVLAAAVYRQNQGQLRVLDGLSATGVRSLRY
CCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
YQEAQADWVWANEGNPDLLETLTTNLRRIPAAQRCISVLSLRQLCLERSLMGDRYDLVDF
HHHHCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
DAFGSGSAFVQDALTVTTLDGLMYLTSTDGRTYSGREPQRALRQGAYGRSHPAVQEQGLR
CCCCCCCHHHHHHHHHEECCCEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHH
LLLGSLAQQAAQRNFGIEPIFSLFWGDTCRIMARLTRKPILTETNYGFLGYCHHCGTYGL
HHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCEECCCCCHHHHHHHCCCCCC
PTWRKLSQATCAHDDLPLTLSGPMWLGKLHHPDYLRQMLAIAQRWHWQDVVKVLETMALE
CHHHHHHHHHCCCCCCCEEECCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NDLPPYFFPLKEIGARAKIDLPKLDSLLNSLQAQGFQASRTHINPQALKTDAPMEKIKAI
CCCCCCEECHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCHHHHCCCCCHHHHHHH
ATQLGAS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA