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The map label for this gene is lpxC [H]

Identifier: 170076947

GI number: 170076947

Start: 333714

End: 334541

Strand: Direct

Name: lpxC [H]

Synonym: SYNPCC7002_A0319

Alternate gene names: 170076947

Gene position: 333714-334541 (Clockwise)

Preceding gene: 170076946

Following gene: 170076950

Centisome position: 11.09

GC content: 54.11

Gene sequence:

>828_bases
ATGGTTAAAACGTTAAAAACAACCGTTGAATGTTCTGGGGTGGGTCTCCATTCGGGGCAACGGGTCACCCTAAGGCTCGT
GCCTGGCGATCGCCACCAGGGTCGTTATTTTGTGCGTACAGATTTACCAGGGCAACCCCAGATCCCGGCCCGCATTGAGG
CCGTCGATCAAACCCTTTTGTCTACGGAATTGGCAGTGGGTGAGGCCAAGGTCAGAACCACAGAGCATTTGTTAGCGGCA
TTGGTGGGTCTTGGGATCGATGTTGTGCGCCTCGAAATAGATGGGCCGGAGTTACCCCTGTTGGATGGCTCGGCAGCGCA
GTGGGTAGAGGCGATCGCCAAGGCAGGCACCCAGACCCTCACAGATGAGGCGATCGCCGTTCCCGTGGTCGCAGAACCCG
TTTGGCTCCGGGAAGATGACGCGTTTGTGGTGGCCTTACCCTCACTGGAACTGCGGTTTACCTATGGCATCGATTTTACC
TACAAGCCCATTGGCAACCAGTGGCACAGTTGGAGCCCCGCAGCAGAGCCCTTTGCCCAGGCGATCGCCCCGGCCCGGAC
GTTTGGCTTTGCCGATCAAATTGAGCAATTGAAAAAAGCTGGTTTAATTCAGGGAGGCAGTCTTGATAATGCCCTCGTTT
GCGATCAAGAAAAATGGCTCAATCCGCCGCTTCGGTTTGACAATGAGCCGGCTCGCCACAAATTACTTGATTTAATCGGG
GATTTGAGTTTGCTGGGCACAATTCCCACGGCCCATTACCTGGCCTATAAAGCAAGCCATAAACTCCATACCCAGCTTGC
CAAAACCTTACAGGCAATGCTTTTCTAA

Upstream 100 bases:

>100_bases
GCTTAACGACCAAGGGGACAGTCGTATTCACTTTGGTATTGGTGAGCGTTTCTAAGGTGTTATCGGTCTGATTTCGTGGG
GGGCACCCCCCTTTTTTGTG

Downstream 100 bases:

>100_bases
AATTCTAATCAAGCTGCTATTGGGTGAAGGATAACGCCGATAGTTTGACTTGTATTGCTGGGGCTGGCGATCGCCTTTTT
TCAGAGACTGCCAACCCCTA

Product: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase

Products: NA

Alternate protein names: UDP-3-O-acyl-GlcNAc deacetylase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MVKTLKTTVECSGVGLHSGQRVTLRLVPGDRHQGRYFVRTDLPGQPQIPARIEAVDQTLLSTELAVGEAKVRTTEHLLAA
LVGLGIDVVRLEIDGPELPLLDGSAAQWVEAIAKAGTQTLTDEAIAVPVVAEPVWLREDDAFVVALPSLELRFTYGIDFT
YKPIGNQWHSWSPAAEPFAQAIAPARTFGFADQIEQLKKAGLIQGGSLDNALVCDQEKWLNPPLRFDNEPARHKLLDLIG
DLSLLGTIPTAHYLAYKASHKLHTQLAKTLQAMLF

Sequences:

>Translated_275_residues
MVKTLKTTVECSGVGLHSGQRVTLRLVPGDRHQGRYFVRTDLPGQPQIPARIEAVDQTLLSTELAVGEAKVRTTEHLLAA
LVGLGIDVVRLEIDGPELPLLDGSAAQWVEAIAKAGTQTLTDEAIAVPVVAEPVWLREDDAFVVALPSLELRFTYGIDFT
YKPIGNQWHSWSPAAEPFAQAIAPARTFGFADQIEQLKKAGLIQGGSLDNALVCDQEKWLNPPLRFDNEPARHKLLDLIG
DLSLLGTIPTAHYLAYKASHKLHTQLAKTLQAMLF
>Mature_275_residues
MVKTLKTTVECSGVGLHSGQRVTLRLVPGDRHQGRYFVRTDLPGQPQIPARIEAVDQTLLSTELAVGEAKVRTTEHLLAA
LVGLGIDVVRLEIDGPELPLLDGSAAQWVEAIAKAGTQTLTDEAIAVPVVAEPVWLREDDAFVVALPSLELRFTYGIDFT
YKPIGNQWHSWSPAAEPFAQAIAPARTFGFADQIEQLKKAGLIQGGSLDNALVCDQEKWLNPPLRFDNEPARHKLLDLIG
DLSLLGTIPTAHYLAYKASHKLHTQLAKTLQAMLF

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0774

COG function: function code M; UDP-3-O-acyl-N-acetylglucosamine deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxC family [H]

Homologues:

Organism=Escherichia coli, GI1786285, Length=277, Percent_Identity=41.1552346570397, Blast_Score=181, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR004463
- InterPro:   IPR011334
- InterPro:   IPR015870 [H]

Pfam domain/function: PF03331 LpxC [H]

EC number: 3.5.1.-

Molecular weight: Translated: 30051; Mature: 30051

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKTLKTTVECSGVGLHSGQRVTLRLVPGDRHQGRYFVRTDLPGQPQIPARIEAVDQTLL
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
STELAVGEAKVRTTEHLLAALVGLGIDVVRLEIDGPELPLLDGSAAQWVEAIAKAGTQTL
HHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCEECCCHHHHHHHHHHCCCCCC
TDEAIAVPVVAEPVWLREDDAFVVALPSLELRFTYGIDFTYKPIGNQWHSWSPAAEPFAQ
CCCCEEEEEEECCEEEECCCEEEEEECCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHH
AIAPARTFGFADQIEQLKKAGLIQGGSLDNALVCDQEKWLNPPLRFDNEPARHKLLDLIG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEECHHHHCCCCCCCCCCHHHHHHHHHHH
DLSLLGTIPTAHYLAYKASHKLHTQLAKTLQAMLF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKTLKTTVECSGVGLHSGQRVTLRLVPGDRHQGRYFVRTDLPGQPQIPARIEAVDQTLL
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
STELAVGEAKVRTTEHLLAALVGLGIDVVRLEIDGPELPLLDGSAAQWVEAIAKAGTQTL
HHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCEECCCHHHHHHHHHHCCCCCC
TDEAIAVPVVAEPVWLREDDAFVVALPSLELRFTYGIDFTYKPIGNQWHSWSPAAEPFAQ
CCCCEEEEEEECCEEEECCCEEEEEECCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHH
AIAPARTFGFADQIEQLKKAGLIQGGSLDNALVCDQEKWLNPPLRFDNEPARHKLLDLIG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEECHHHHCCCCCCCCCCHHHHHHHHHHH
DLSLLGTIPTAHYLAYKASHKLHTQLAKTLQAMLF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on carbon-nitrogen bonds, other than peptide bonds; In linear amides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA