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The map label for this gene is ppnK [H]

Identifier: 170076848

GI number: 170076848

Start: 228807

End: 229748

Strand: Direct

Name: ppnK [H]

Synonym: SYNPCC7002_A0217

Alternate gene names: 170076848

Gene position: 228807-229748 (Clockwise)

Preceding gene: 170076847

Following gene: 170076849

Centisome position: 7.61

GC content: 55.31

Gene sequence:

>942_bases
GTGCCCAAAGCCGGCATTATCTATAACGACATCAAACCCATTGCCTGCCAAGTCGCTCAGGAATTAGCCAAAACCTTGAG
GAATAAAGGGTGGGAAGTGTTTACGGCCACTGGATTTGGCGGTCTACTTGGCTATGCAGAATGTCCGCCAACCCAGGAAA
CGGGCCACCAACAGCCCGTATGTCACACCAAAATTGAGCAATTGGTGCCCCCCAACTTCGATGAAAATATGCAGTTTGCC
GTGGTTCTGGGGGGAGATGGCACAGTCTTGTCAGCCGCACGCCAAGTTGCTCCAAAGGGAATCCCGCTGCTGACGGTCAA
TACGGGACACCTCGGATTTTTAACGGAAATGTATCTTCAGCACCTCGATGAGGCGATCGCCCAGCTTTTAGCCGGAGAAT
ACGAAATTGAAGACCGTTCGATGATCACCGTGCAGCTTTTCCGCGACGGGGAACTCCTTTGGGAAGCCCTCAGTCTCAAT
GAAATGGTGCTCCACCGGGAACCCCTAGCCGGGATGTGCCACTTTGAAATCCAGATTGGTCGCCATGCCCCCGTTGATAT
TGCCGCCGATGGCATCATGATTTCGACGCCCACCGGTTCCACAGCCTATTCCCTCAGTGCGGGTGGCCCCGTCGTTACCC
CCGATGTGCCCGTTTTTCAGCTCGCCCCCATTTGTCCCCATTCCCTCGCGTCCCGGGCCCTCGTCTTTTCGGACACAGAA
CCGGTGAATATTTTTCCGGCAACGTCCCACCGCTTGGTGATGGTCGTTGATGGTAACGGTGGGGCCTATGTCTTGCCGGA
GGATCAAGTCCATTTAGAGCGATCGCCTTACAATGCCCGCTTTGTACGCCTCCACCGACCCGAATTTTTCCGAATCCTCC
GGGAGAAGCTGGGCTGGGGACTCCCCCACGTGGCGAAACCCACATCCCGCAAAGTTCTTTAG

Upstream 100 bases:

>100_bases
GTTTCATTAGTGGCGATCGCCAACCGTATCGGTATTAAGGGAAACGGTTTGAGTGATACCCTATTGTTTATATCCTTAAG
TTTGTAGGACACTTCTACTT

Downstream 100 bases:

>100_bases
GGAAATGGCATCAGAAGCAAAGATTCATGAAAATTTGTCTTTCCCCAAATTGAGCCTTTCTAGAATCAAAAAGATTACCC
CTTGAGCTTTTTTATTTAGC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPKAGIIYNDIKPIACQVAQELAKTLRNKGWEVFTATGFGGLLGYAECPPTQETGHQQPVCHTKIEQLVPPNFDENMQFA
VVLGGDGTVLSAARQVAPKGIPLLTVNTGHLGFLTEMYLQHLDEAIAQLLAGEYEIEDRSMITVQLFRDGELLWEALSLN
EMVLHREPLAGMCHFEIQIGRHAPVDIAADGIMISTPTGSTAYSLSAGGPVVTPDVPVFQLAPICPHSLASRALVFSDTE
PVNIFPATSHRLVMVVDGNGGAYVLPEDQVHLERSPYNARFVRLHRPEFFRILREKLGWGLPHVAKPTSRKVL

Sequences:

>Translated_313_residues
MPKAGIIYNDIKPIACQVAQELAKTLRNKGWEVFTATGFGGLLGYAECPPTQETGHQQPVCHTKIEQLVPPNFDENMQFA
VVLGGDGTVLSAARQVAPKGIPLLTVNTGHLGFLTEMYLQHLDEAIAQLLAGEYEIEDRSMITVQLFRDGELLWEALSLN
EMVLHREPLAGMCHFEIQIGRHAPVDIAADGIMISTPTGSTAYSLSAGGPVVTPDVPVFQLAPICPHSLASRALVFSDTE
PVNIFPATSHRLVMVVDGNGGAYVLPEDQVHLERSPYNARFVRLHRPEFFRILREKLGWGLPHVAKPTSRKVL
>Mature_312_residues
PKAGIIYNDIKPIACQVAQELAKTLRNKGWEVFTATGFGGLLGYAECPPTQETGHQQPVCHTKIEQLVPPNFDENMQFAV
VLGGDGTVLSAARQVAPKGIPLLTVNTGHLGFLTEMYLQHLDEAIAQLLAGEYEIEDRSMITVQLFRDGELLWEALSLNE
MVLHREPLAGMCHFEIQIGRHAPVDIAADGIMISTPTGSTAYSLSAGGPVVTPDVPVFQLAPICPHSLASRALVFSDTEP
VNIFPATSHRLVMVVDGNGGAYVLPEDQVHLERSPYNARFVRLHRPEFFRILREKLGWGLPHVAKPTSRKVL

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=260, Percent_Identity=25.3846153846154, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788968, Length=297, Percent_Identity=30.976430976431, Blast_Score=141, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320794, Length=251, Percent_Identity=29.4820717131474, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322509, Length=248, Percent_Identity=29.0322580645161, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6325068, Length=166, Percent_Identity=32.5301204819277, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573832, Length=182, Percent_Identity=31.3186813186813, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573830, Length=226, Percent_Identity=28.3185840707965, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI161077047, Length=182, Percent_Identity=31.3186813186813, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28573828, Length=226, Percent_Identity=28.3185840707965, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573826, Length=182, Percent_Identity=31.3186813186813, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129957, Length=277, Percent_Identity=25.9927797833935, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363323, Length=282, Percent_Identity=25.886524822695, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653422, Length=282, Percent_Identity=25.886524822695, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363321, Length=282, Percent_Identity=25.886524822695, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653424, Length=282, Percent_Identity=25.886524822695, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 34287; Mature: 34156

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAGIIYNDIKPIACQVAQELAKTLRNKGWEVFTATGFGGLLGYAECPPTQETGHQQPV
CCCCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCH
CHTKIEQLVPPNFDENMQFAVVLGGDGTVLSAARQVAPKGIPLLTVNTGHLGFLTEMYLQ
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
HLDEAIAQLLAGEYEIEDRSMITVQLFRDGELLWEALSLNEMVLHREPLAGMCHFEIQIG
HHHHHHHHHHCCCEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
RHAPVDIAADGIMISTPTGSTAYSLSAGGPVVTPDVPVFQLAPICPHSLASRALVFSDTE
CCCCCEEEECCEEEECCCCCCEEEECCCCCEECCCCCCEEECCCCCHHHHCCEEEEECCC
PVNIFPATSHRLVMVVDGNGGAYVLPEDQVHLERSPYNARFVRLHRPEFFRILREKLGWG
CCEEEECCCCEEEEEEECCCCEEECCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHCCC
LPHVAKPTSRKVL
CCCCCCCCCCCCC
>Mature Secondary Structure 
PKAGIIYNDIKPIACQVAQELAKTLRNKGWEVFTATGFGGLLGYAECPPTQETGHQQPV
CCCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCH
CHTKIEQLVPPNFDENMQFAVVLGGDGTVLSAARQVAPKGIPLLTVNTGHLGFLTEMYLQ
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
HLDEAIAQLLAGEYEIEDRSMITVQLFRDGELLWEALSLNEMVLHREPLAGMCHFEIQIG
HHHHHHHHHHCCCEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
RHAPVDIAADGIMISTPTGSTAYSLSAGGPVVTPDVPVFQLAPICPHSLASRALVFSDTE
CCCCCEEEECCEEEECCCCCCEEEECCCCCEECCCCCCEEECCCCCHHHHCCEEEEECCC
PVNIFPATSHRLVMVVDGNGGAYVLPEDQVHLERSPYNARFVRLHRPEFFRILREKLGWG
CCEEEECCCCEEEEEEECCCCEEECCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHCCC
LPHVAKPTSRKVL
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]