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The map label for this gene is hoxE [H]

Identifier: 170076826

GI number: 170076826

Start: 206263

End: 206754

Strand: Direct

Name: hoxE [H]

Synonym: SYNPCC7002_A0195

Alternate gene names: 170076826

Gene position: 206263-206754 (Clockwise)

Preceding gene: 170076825

Following gene: 170076827

Centisome position: 6.86

GC content: 49.59

Gene sequence:

>492_bases
ATGGCCATTTCCCATGCGGTTCCTGCGGATAAACGTTTTCGGGTGCTGGAAGTCGCCATGAAACGGAATCAATATCGCCA
AGATACCCTGATTGAGATTCTGCACAAGGCCCAGGAAGTCTTTGGTTACCTCGAAGATGAGGTACTTGAATACGTGGCGC
GGGGATTGAAACTGCCCCTCAGCCGGGTGTATGGGGTGGCGACGTTTTATCATTTATTTTCTTTAAAGCCGAAAGGAAAA
CATACTTGTGTCGTGTGTTTGGGGACGGCGTGCTATGTGAAAGGCTCCCAAGAACTCCTCGATAAAATTGATGAAACTCT
CCACATTAAACCCGGGGAAACAACCCCTGATGATCAAATTTCTTTGGTTACGGCGCGCTGTATTGGGGCCTGTGGGATTG
CGCCAGCGGTAGTTTATGACGATGAGGTGTGCGGCAAACAGAACGCTGATCAGGTGATGGCAAGGTTGCGGCAGTTGTCT
GAAGGAAGTTGA

Upstream 100 bases:

>100_bases
AGGTTTCAAGGCGTTTAATTGATCCTTGGGATTAATCCTTTTTAAGATGAAAGCAAAGGCGATCGCCGCCTGATTTTTAC
TGTCATTTGAGACGATTACC

Downstream 100 bases:

>100_bases
CAGGTATCAGGGATCAGAATTTCGGTGTTTGATTTGTAGTCAGGATTTGCGGGAAAGATGACGGATTTAGCGGAATTGTT
TGAAATTGCGGAAGCGGAAC

Product: hydrogenase subunit E ([NiFe] hydrogenase subunit)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MAISHAVPADKRFRVLEVAMKRNQYRQDTLIEILHKAQEVFGYLEDEVLEYVARGLKLPLSRVYGVATFYHLFSLKPKGK
HTCVVCLGTACYVKGSQELLDKIDETLHIKPGETTPDDQISLVTARCIGACGIAPAVVYDDEVCGKQNADQVMARLRQLS
EGS

Sequences:

>Translated_163_residues
MAISHAVPADKRFRVLEVAMKRNQYRQDTLIEILHKAQEVFGYLEDEVLEYVARGLKLPLSRVYGVATFYHLFSLKPKGK
HTCVVCLGTACYVKGSQELLDKIDETLHIKPGETTPDDQISLVTARCIGACGIAPAVVYDDEVCGKQNADQVMARLRQLS
EGS
>Mature_162_residues
AISHAVPADKRFRVLEVAMKRNQYRQDTLIEILHKAQEVFGYLEDEVLEYVARGLKLPLSRVYGVATFYHLFSLKPKGKH
TCVVCLGTACYVKGSQELLDKIDETLHIKPGETTPDDQISLVTARCIGACGIAPAVVYDDEVCGKQNADQVMARLRQLSE
GS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=138, Percent_Identity=35.5072463768116, Blast_Score=90, Evalue=9e-19,
Organism=Escherichia coli, GI1788621, Length=113, Percent_Identity=33.6283185840708, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561328, Length=118, Percent_Identity=36.4406779661017, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI18859877, Length=118, Percent_Identity=38.135593220339, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355353, Length=114, Percent_Identity=34.2105263157895, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18126; Mature: 17995

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISHAVPADKRFRVLEVAMKRNQYRQDTLIEILHKAQEVFGYLEDEVLEYVARGLKLPL
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SRVYGVATFYHLFSLKPKGKHTCVVCLGTACYVKGSQELLDKIDETLHIKPGETTPDDQI
HHHHHHHHHHHHHHCCCCCCCEEEEEECCHHEECCCHHHHHHHHHHEECCCCCCCCCHHH
SLVTARCIGACGIAPAVVYDDEVCGKQNADQVMARLRQLSEGS
HHHHHHHHHHCCCCCCEEECCHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AISHAVPADKRFRVLEVAMKRNQYRQDTLIEILHKAQEVFGYLEDEVLEYVARGLKLPL
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SRVYGVATFYHLFSLKPKGKHTCVVCLGTACYVKGSQELLDKIDETLHIKPGETTPDDQI
HHHHHHHHHHHHHHCCCCCCCEEEEEECCHHEECCCHHHHHHHHHHEECCCCCCCCCHHH
SLVTARCIGACGIAPAVVYDDEVCGKQNADQVMARLRQLSEGS
HHHHHHHHHHCCCCCCEEECCHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]