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The map label for this gene is gpo [C]

Identifier: 170076750

GI number: 170076750

Start: 118054

End: 118548

Strand: Direct

Name: gpo [C]

Synonym: SYNPCC7002_A0117

Alternate gene names: 170076750

Gene position: 118054-118548 (Clockwise)

Preceding gene: 170076748

Following gene: 170076752

Centisome position: 3.92

GC content: 43.03

Gene sequence:

>495_bases
ATGACGACACAAACGCCTACTTCTATTTATGATTTTTCGGCCACGGCCATCGATGGCACATCGGTCGATCTTAGTACCTA
TAAAGATCAGGTTTTATTGATTGTCAATACAGCCAGCCAATGTGGATTCACTCCCCAATACAAAGGTTTGCAGGCGCTCC
ATGAACAATATGGCAACAAAGGCTTAGTTGTCCTCGGCTTCCCCTGTAACCAGTTTGGCCAACAAGAACCCGGCAACGAA
TCGCAAATCCAATCATTTTGTGAAACAACGTTTGGGGTTTCTTTTCCGATGTTTCAAAAAATTGATGTTAATGGCAGCAA
TGCTCACCCGTTATATCAATATTTAACCAAAGAAGTACCCGGTATTTTGGGGACAAAAAATGTGAAATGGAACTTCACAA
AATTCCTCATTAACCGTCAGGGTCAAGTGGTAAAACGCTATGCACCCACGGCAACACCGGAGGCGATCGCCAAAGATATC
CAGGAATTACTTTAA

Upstream 100 bases:

>100_bases
GTGGTCTTATCTCTAAGACTCATTTACACTCTGCTGAAATAATGAATATAATGCTTGCGAGATTGTTTTAAACAGCTTCT
ACAAATATTTTTTCGAGTTT

Downstream 100 bases:

>100_bases
AGATTATTTTCCCTAGAAAACGGTTTATTTTTTGAAACTGATTAACCCCCAGGTTTGCATTGGACTTGGGGGCTTTTTCT
TTTATTTCAAGGACAATTCA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTTQTPTSIYDFSATAIDGTSVDLSTYKDQVLLIVNTASQCGFTPQYKGLQALHEQYGNKGLVVLGFPCNQFGQQEPGNE
SQIQSFCETTFGVSFPMFQKIDVNGSNAHPLYQYLTKEVPGILGTKNVKWNFTKFLINRQGQVVKRYAPTATPEAIAKDI
QELL

Sequences:

>Translated_164_residues
MTTQTPTSIYDFSATAIDGTSVDLSTYKDQVLLIVNTASQCGFTPQYKGLQALHEQYGNKGLVVLGFPCNQFGQQEPGNE
SQIQSFCETTFGVSFPMFQKIDVNGSNAHPLYQYLTKEVPGILGTKNVKWNFTKFLINRQGQVVKRYAPTATPEAIAKDI
QELL
>Mature_163_residues
TTQTPTSIYDFSATAIDGTSVDLSTYKDQVLLIVNTASQCGFTPQYKGLQALHEQYGNKGLVVLGFPCNQFGQQEPGNES
QIQSFCETTFGVSFPMFQKIDVNGSNAHPLYQYLTKEVPGILGTKNVKWNFTKFLINRQGQVVKRYAPTATPEAIAKDIQ
ELL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=160, Percent_Identity=46.875, Blast_Score=144, Evalue=2e-35,
Organism=Homo sapiens, GI90903240, Length=160, Percent_Identity=46.875, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI15618997, Length=162, Percent_Identity=44.4444444444444, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI192455698, Length=158, Percent_Identity=40.5063291139241, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI90903238, Length=135, Percent_Identity=45.9259259259259, Blast_Score=118, Evalue=3e-27,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=38.150289017341, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=36.4161849710983, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=34.8066298342541, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=35.1648351648352, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=7e-21,
Organism=Escherichia coli, GI1788003, Length=157, Percent_Identity=43.9490445859873, Blast_Score=153, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=47.7987421383648, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=45.9119496855346, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=41.1392405063291, Blast_Score=136, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=43.8271604938272, Blast_Score=133, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI193209493, Length=183, Percent_Identity=33.879781420765, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17550320, Length=168, Percent_Identity=35.1190476190476, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=40, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71999642, Length=79, Percent_Identity=39.2405063291139, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193210709, Length=79, Percent_Identity=48.1012658227848, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507603, Length=98, Percent_Identity=39.7959183673469, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=51.2658227848101, Blast_Score=184, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6322228, Length=158, Percent_Identity=44.9367088607595, Blast_Score=172, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322826, Length=157, Percent_Identity=43.312101910828, Blast_Score=152, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24656777, Length=164, Percent_Identity=46.9512195121951, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24656767, Length=164, Percent_Identity=46.9512195121951, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24656772, Length=164, Percent_Identity=46.9512195121951, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=41.5094339622642, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18167; Mature: 18036

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQTPTSIYDFSATAIDGTSVDLSTYKDQVLLIVNTASQCGFTPQYKGLQALHEQYGNK
CCCCCCCCEEECCCEEECCCCCCCCCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHCCC
GLVVLGFPCNQFGQQEPGNESQIQSFCETTFGVSFPMFQKIDVNGSNAHPLYQYLTKEVP
CEEEEECCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCC
GILGTKNVKWNFTKFLINRQGQVVKRYAPTATPEAIAKDIQELL
CCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
TTQTPTSIYDFSATAIDGTSVDLSTYKDQVLLIVNTASQCGFTPQYKGLQALHEQYGNK
CCCCCCCEEECCCEEECCCCCCCCCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHCCC
GLVVLGFPCNQFGQQEPGNESQIQSFCETTFGVSFPMFQKIDVNGSNAHPLYQYLTKEVP
CEEEEECCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCC
GILGTKNVKWNFTKFLINRQGQVVKRYAPTATPEAIAKDIQELL
CCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]