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The map label for this gene is gap [H]

Identifier: 170076739

GI number: 170076739

Start: 107108

End: 108124

Strand: Direct

Name: gap [H]

Synonym: SYNPCC7002_A0106

Alternate gene names: 170076739

Gene position: 107108-108124 (Clockwise)

Preceding gene: 170076734

Following gene: 170076742

Centisome position: 3.56

GC content: 50.25

Gene sequence:

>1017_bases
GTGATTAGAGTAGCGATTAATGGATTTGGACGTATTGGACGCAACTTCTTGAGATGTTGGGCTGGTCGCGAAAACAGCCA
ACTCCAAGTCGTTGGGATCAATGCGACCACCGATACCAAAAGTAATGCCCACATGCTTCGTTATGACACGATGCTGGGTA
AATTTGATGGCGAAATCGATTATGACGCCAACTCTCTGACTGTCAACGGCAACGTAATCAAATGCTGTTCCGACAGAAAC
CCCCTCAACCTCCCTTGGAAAGAGTGGGGCGTCGATTTGGTGATCGAATCTACCGGTGTATTCAACACCGAAGAAGGATC
TTCTAAGCACATTACAGCTGGTGCACAAAAAGTATTGATCACAGCCCCTGGTAAAGGCGGCCATATCGGCACCTATGTAG
TTGGTGTAAACGCCGATCAGTATGGCCACGACAAACAAAATGTCATCAGTAATGCCAGCTGTACCACCAACTGCCTCGCC
CCCATTGTTAAAGTACTCAATGATCGTTTTGGGATCGTCAAAGGGACGATGACCACCGTCCACAGTTACACTGGCGACCA
ACGTATCCTCGACAACAGCCACCGGGATCTCCGTCGGGCGCGGGCAGCCGCAGAAAATATTGTGCCGACTTCTACTGGCG
CAGCTAAAGCCGTTGCCTTAGTTATTCCCGAAATGAAGGGTAAGCTCAACGGGATCGCCATGCGGGTACCGACTCCCAAC
GTCTCCGTAGTTGACCTGGTTGCCCAAGTAGCGAAGCCCACCATTGCTGAGGAAGTTAACCAAGTTCTGAAAGAAGCTTC
TGAAACCTACATGAAAGGGATTTTGGCTTACACCGAAGAACCCCTCGTCTCCTGTGACTTCCGGGGAACTGATGTCTCTT
CCACCATTGACGGTAGCCTCACCCTCGCCATGGACGGTGACCTAATTAAAGTTGTGGCTTGGTACGACAACGAGTGGGGT
TATTCTCAACGGGTTGTTGACCTCGCAGAAATCGTTGCCCAAAATTGGCAAGGGTAA

Upstream 100 bases:

>100_bases
CCCGAAATTCGGGGATCGAATTGTGCAGTCTTTGATATGATTGGGGTCATCAAATGAAAACTTTTATTGCAATTTAATCT
TTAATAGAGGGCAAGACGCG

Downstream 100 bases:

>100_bases
TTTTCCAAAACGATATGCGCCATGTCTGATCTGACATTGATGTTGAACTAGGATTTGATATTTAGTCAGGTAGGGCAAGT
TACAAATCAATAGTAAAAAA

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH 2; GAP-2; NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIRVAINGFGRIGRNFLRCWAGRENSQLQVVGINATTDTKSNAHMLRYDTMLGKFDGEIDYDANSLTVNGNVIKCCSDRN
PLNLPWKEWGVDLVIESTGVFNTEEGSSKHITAGAQKVLITAPGKGGHIGTYVVGVNADQYGHDKQNVISNASCTTNCLA
PIVKVLNDRFGIVKGTMTTVHSYTGDQRILDNSHRDLRRARAAAENIVPTSTGAAKAVALVIPEMKGKLNGIAMRVPTPN
VSVVDLVAQVAKPTIAEEVNQVLKEASETYMKGILAYTEEPLVSCDFRGTDVSSTIDGSLTLAMDGDLIKVVAWYDNEWG
YSQRVVDLAEIVAQNWQG

Sequences:

>Translated_338_residues
MIRVAINGFGRIGRNFLRCWAGRENSQLQVVGINATTDTKSNAHMLRYDTMLGKFDGEIDYDANSLTVNGNVIKCCSDRN
PLNLPWKEWGVDLVIESTGVFNTEEGSSKHITAGAQKVLITAPGKGGHIGTYVVGVNADQYGHDKQNVISNASCTTNCLA
PIVKVLNDRFGIVKGTMTTVHSYTGDQRILDNSHRDLRRARAAAENIVPTSTGAAKAVALVIPEMKGKLNGIAMRVPTPN
VSVVDLVAQVAKPTIAEEVNQVLKEASETYMKGILAYTEEPLVSCDFRGTDVSSTIDGSLTLAMDGDLIKVVAWYDNEWG
YSQRVVDLAEIVAQNWQG
>Mature_338_residues
MIRVAINGFGRIGRNFLRCWAGRENSQLQVVGINATTDTKSNAHMLRYDTMLGKFDGEIDYDANSLTVNGNVIKCCSDRN
PLNLPWKEWGVDLVIESTGVFNTEEGSSKHITAGAQKVLITAPGKGGHIGTYVVGVNADQYGHDKQNVISNASCTTNCLA
PIVKVLNDRFGIVKGTMTTVHSYTGDQRILDNSHRDLRRARAAAENIVPTSTGAAKAVALVIPEMKGKLNGIAMRVPTPN
VSVVDLVAQVAKPTIAEEVNQVLKEASETYMKGILAYTEEPLVSCDFRGTDVSSTIDGSLTLAMDGDLIKVVAWYDNEWG
YSQRVVDLAEIVAQNWQG

Specific function: Works with both NADP and NAD [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=46.2006079027356, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=46.5045592705167, Blast_Score=298, Evalue=4e-81,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=50, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1789295, Length=328, Percent_Identity=44.2073170731707, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=47.4777448071217, Blast_Score=303, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=47.1810089020772, Blast_Score=303, Evalue=8e-83,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=46.5875370919881, Blast_Score=301, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=46.5875370919881, Blast_Score=301, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=48.8095238095238, Blast_Score=325, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=49.702380952381, Blast_Score=325, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=47.6190476190476, Blast_Score=317, Evalue=2e-87,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=46.0606060606061, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=46.0606060606061, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=45.4545454545455, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=45.4545454545455, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI19922412, Length=339, Percent_Identity=44.8377581120944, Blast_Score=286, Evalue=1e-77,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 36661; Mature: 36661

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVAINGFGRIGRNFLRCWAGRENSQLQVVGINATTDTKSNAHMLRYDTMLGKFDGEID
CEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEHHHHCCCCEEE
YDANSLTVNGNVIKCCSDRNPLNLPWKEWGVDLVIESTGVFNTEEGSSKHITAGAQKVLI
CCCCEEEECCCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCCEEECCCCEEEE
TAPGKGGHIGTYVVGVNADQYGHDKQNVISNASCTTNCLAPIVKVLNDRFGIVKGTMTTV
ECCCCCCCEEEEEEEECCHHCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECHHHHH
HSYTGDQRILDNSHRDLRRARAAAENIVPTSTGAAKAVALVIPEMKGKLNGIAMRVPTPN
ECCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCHHEEEEEECCCCCCCCCEEEEECCCC
VSVVDLVAQVAKPTIAEEVNQVLKEASETYMKGILAYTEEPLVSCDFRGTDVSSTIDGSL
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEE
TLAMDGDLIKVVAWYDNEWGYSQRVVDLAEIVAQNWQG
EEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRVAINGFGRIGRNFLRCWAGRENSQLQVVGINATTDTKSNAHMLRYDTMLGKFDGEID
CEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEHHHHCCCCEEE
YDANSLTVNGNVIKCCSDRNPLNLPWKEWGVDLVIESTGVFNTEEGSSKHITAGAQKVLI
CCCCEEEECCCEEEEECCCCCCCCCHHHCCEEEEEECCCCEECCCCCCCEEECCCCEEEE
TAPGKGGHIGTYVVGVNADQYGHDKQNVISNASCTTNCLAPIVKVLNDRFGIVKGTMTTV
ECCCCCCCEEEEEEEECCHHCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECHHHHH
HSYTGDQRILDNSHRDLRRARAAAENIVPTSTGAAKAVALVIPEMKGKLNGIAMRVPTPN
ECCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCHHEEEEEECCCCCCCCCEEEEECCCC
VSVVDLVAQVAKPTIAEEVNQVLKEASETYMKGILAYTEEPLVSCDFRGTDVSSTIDGSL
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEE
TLAMDGDLIKVVAWYDNEWGYSQRVVDLAEIVAQNWQG
EEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9226260; 8905231 [H]