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The map label for this gene is deoC2 [H]

Identifier: 170025842

GI number: 170025842

Start: 4002740

End: 4003537

Strand: Reverse

Name: deoC2 [H]

Synonym: YPK_3627

Alternate gene names: 170025842

Gene position: 4003537-4002740 (Counterclockwise)

Preceding gene: 170025843

Following gene: 170025841

Centisome position: 85.37

GC content: 50.38

Gene sequence:

>798_bases
ATGACCGATTTAACCGCCTGCGCGCATTTGAACGATTATGCTAAACGCGCGCTAAGTTTGATGGATTTAACCACCCTGAA
TGACGACGATACCGATGAAAAAGTGATCGCGCTCTGTCATCAGGCTAAAAGCCCGGCCGGTAATACCGCGGCAATTTGTA
TTTATCCTCGCTTTATCCCGGTTGCCCGTAAGGCGTTACGTGAACAGGGCACTCCTGAGATCCGTATCGCAACGGTGACC
AACTTCCCTCATGGCAATGATGATGTTGCGATTGCGTTGGCTGAAACCCGTGCTGCCATTGCTTATGGTGCCGATGAAGT
GGATGTGGTTTTCCCTTATCGCGCGTTAATGGCCGGTAACGATAAAATTGGCTTCGAACTCGTGAAAACGTGTAAAGAAG
CCTGCGCTGCGGCGAATGTATTACTGAAAGTCATCATTGAAACTGGCGAACTTAAGCAAGCGCATTTAATTCGTCAGGCC
TCTGAAATTGCAATCAAAGCGGGTGCCGATTTTATTAAAACTTCTACCGGTAAAGTGCCGGTGAATGCCTCGTTGGAAAG
TGCAGACATTATGATCCGCACTATCCGTGAGTTAGGCGTAGGCGAAACGGTGGGCTTCAAACCGGCTGGTGGTGTCCGTA
CCGCAGAAGATGCCGCGCAATTTTTGCAATTGGCTGATCAACTGATGGGGGAAGGCTGGGCTGATGCACGCCATTTCCGC
TTTGGCGCTTCCAGTCTACTCGCCAGTTTGCTGACCACATTGGGTCACCAGAGTAACGCCAACAGCAGCGGCTACTAA

Upstream 100 bases:

>100_bases
AGCTTAACCACCGAGAGATACCGCCAAGGATCTTTTCTGCTCATAACTACATGCTCAGTTTTGGCAAACTGCCGGAGCTG
AAACAGTGTTGGAGAGTTTT

Downstream 100 bases:

>100_bases
CGTTATTATCATCATTACACTGAATTGATGCACTGTAGGCTGAAGGCCTGCCGTGTCGCTATTTCCGAAAGCGCTTGTGG
GCGGCTTTCATCCCATATTC

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase 2; DERA 2; Deoxyriboaldolase 2 [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIPVARKALREQGTPEIRIATVT
NFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAHLIRQA
SEIAIKAGADFIKTSTGKVPVNASLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWADARHFR
FGASSLLASLLTTLGHQSNANSSGY

Sequences:

>Translated_265_residues
MTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIPVARKALREQGTPEIRIATVT
NFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAHLIRQA
SEIAIKAGADFIKTSTGKVPVNASLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWADARHFR
FGASSLLASLLTTLGHQSNANSSGY
>Mature_264_residues
TDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIPVARKALREQGTPEIRIATVTN
FPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGNDKIGFELVKTCKEACAAANVLLKVIIETGELKQAHLIRQAS
EIAIKAGADFIKTSTGKVPVNASLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWADARHFRF
GASSLLASLLTTLGHQSNANSSGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116063554, Length=267, Percent_Identity=37.0786516853933, Blast_Score=165, Evalue=3e-41,
Organism=Escherichia coli, GI1790841, Length=265, Percent_Identity=78.1132075471698, Blast_Score=383, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17533015, Length=251, Percent_Identity=37.0517928286853, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19922098, Length=255, Percent_Identity=37.2549019607843, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.4 [H]

Molecular weight: Translated: 28260; Mature: 28129

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIP
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCHHH
VARKALREQGTPEIRIATVTNFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGN
HHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEECHHHHEEECCCCEEEEECHHHHHCCC
DKIGFELVKTCKEACAAANVLLKVIIETGELKQAHLIRQASEIAIKAGADFIKTSTGKVP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
VNASLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWADARHFR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
FGASSLLASLLTTLGHQSNANSSGY
CCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TDLTACAHLNDYAKRALSLMDLTTLNDDDTDEKVIALCHQAKSPAGNTAAICIYPRFIP
CCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCHHH
VARKALREQGTPEIRIATVTNFPHGNDDVAIALAETRAAIAYGADEVDVVFPYRALMAGN
HHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEECHHHHEEECCCCEEEEECHHHHHCCC
DKIGFELVKTCKEACAAANVLLKVIIETGELKQAHLIRQASEIAIKAGADFIKTSTGKVP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCC
VNASLESADIMIRTIRELGVGETVGFKPAGGVRTAEDAAQFLQLADQLMGEGWADARHFR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
FGASSLLASLLTTLGHQSNANSSGY
CCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]