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The map label for this gene is irgA [H]

Identifier: 170025624

GI number: 170025624

Start: 3741154

End: 3743250

Strand: Reverse

Name: irgA [H]

Synonym: YPK_3409

Alternate gene names: 170025624

Gene position: 3743250-3741154 (Counterclockwise)

Preceding gene: 170025633

Following gene: 170025623

Centisome position: 79.82

GC content: 47.45

Gene sequence:

>2097_bases
ATGTCAAATAAAACAATAGCGTTCGCGTTAGTAGTGGCATCATCAGCCCCTGTTATCGCAGCAGATAATGACAATATTAT
GGTTGTTACCGCATCGGGATATGAACAGAAGATCAGAGAGGCTGCGGCAAGCATCTCGGTCATTAGCCAAAATGAATTAC
GTCAGCGCAATTACAACGATTTGGCGCAAGCGCTGAGTGATGTTGAAGGTGTTGACGTCAATAGCAGCACGGGGAAAACC
GGGGGGCTGGATATCAGTATTCGTGGTATGCCCAGCGCTTATACCCTGATATTGGTGGATGGGATCCGGCAAAATGGCAC
TTCCGATGTAACGCCAAATGGCTTTGGTGCCATGAATACCAGCTTTATGCCCCCGCTATCGGCCATTGAGCGCATCGAAG
TGATCAGGGGACCGATGTCAACGCTCTACGGTTCTGATGCTATCGGTGGTGTTGTTAATATCATCACAAAAAAGATCACC
AAAGCGTGGGCCAGCTCAGCAACGCTTGAACACACCTTCCAGGAAAATACGGCTTTTGGTGACAGTTCAAAGTTCTCTTT
TTACTCCAGTGGGCCAGCGGTTGAAGATCAACTGGGGCTGTCGTTACGTGGCACGATTTTCCGGCGCGATGCCTCTCGCG
TTGAATCCTCCAATACGGGAGTAGAATTAAGCCGTCGTGGTCCCAATCCAGTAAAAGCAGACAACTATAATCTCGGTGGC
AAACTATTTTGGCAATTGAATACCCAAAGCACCTTGTGGTTGGATGGTGATATTGCTAACCAAAAATATGATAACAGTGC
CAACCAACTAGGTACCATTGGTGCACGAGGCGGTTACGAAGATACTCTGCGTTATCAACGCCGTAAAATAACCTTGGGCA
ACGATAATCGTTTGGACTTTGGTACCTGGAATTCGAGCTTATCTTATAACCAAACTGAAAATATTGGCCGCTTAATCACC
AATGCATCCGTGCCCCAAGGCTCTGGGTTGGCAGGTGAAAAACGTCTGTTGAAAAATACCAATATCATCCTTGATAGCAA
GCTGGTCGCCCCGCTGGGTGATAACCACATGGTGACCCTTGGCGGTCAATATTGGAATGCCATCATGAAAGACGGCATCG
TACTGGCAAATAATGGCGATGAGTTTGCACAAGATGCCTGGTCATTATTCAGCGAAGATGAATGGCGTCTGCTGGACTCA
CTGGCATTAACCTATGGCGCACGTTATGAATATCAAACTACGTTTGGCGGCCATATTAGCCCACGAGCCTATCTGGTGTG
GGACGCACAGGATAACTGGACGGTGAAAGGGGGTGTCAGCACGGGGTATAAAACCCCCACTCTAGCCCAGTTGCATAATG
GGATTAGCGGTGTCACAGGCCAAGGCACCATCACGACGATTGGTAACCCTAAGCTTGAACCAGAGAGTAGTGTCAACACC
GAGGTCGGTGTCTATTATGAAAACGAAACGGGATTTGGCGCTAATGTGACGCTGTTCCACAACCGCTTCAGGAACAAAAT
CAACAGCGTTTCGATTGATAATACCACCAGCACCTACACCAACGTCGGTAAAGCGATCACGCAGGGTATTGAGGTCGCAT
CCACCATACCACTCTGGTCTGACGATTGGATGCTGGGAATAAATTACACCTTTACCGATAGTGAACAGAAAGATGGCAAC
AATAAAGGGGCTCGCCTGACGAATACACCGAAAAATATGGTTAATGCCCGCCTGAACTGGAATATCAACGAGCAGTTGTC
CACTTGGTTGAAAGCGGAGTATCGCAGTAAAACGGCACGTTTTACCCAAAATTACGCGAATTTGTCTGCGGCAAACAAAG
TGGTTTACAACAATTTAGGCTCAGAGTTTAAACCTTTTAGCGTACTTAATTTGGGGGTGGCCTATAAGGTCACTAAGGAT
GTGACACTGAATGGTGCAGTCAATAACCTGTTGGATAAAGATTTTACTCGCACCCACATTTTTGCTGTGGGGAACGGCAC
CACTACTGCGGGTGATTACTTCACCTCGTCTCAAAGCACTGCCGGTTATGTTGTACCTGGCCGTAATTACTGGGTATCCG
TGAATGTTAATTTCTAG

Upstream 100 bases:

>100_bases
TAATGATAATTGATATCATTTGCTTTTACATTTATGCGTATATAATTACAATAGCCTTGAGGTATAAAAAACGAACATAA
ATTTGCTAGAGGCGTATAAA

Downstream 100 bases:

>100_bases
GTATTAGCGTTGTGAGCCATATCGGTAAGGCAGAATTCTGACGAAGAAGTCTATTGGAATTGGCTGAACGACCAAAACAT
CGGTTTATCATGCTGATCTG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSNKTIAFALVVASSAPVIAADNDNIMVVTASGYEQKIREAAASISVISQNELRQRNYNDLAQALSDVEGVDVNSSTGKT
GGLDISIRGMPSAYTLILVDGIRQNGTSDVTPNGFGAMNTSFMPPLSAIERIEVIRGPMSTLYGSDAIGGVVNIITKKIT
KAWASSATLEHTFQENTAFGDSSKFSFYSSGPAVEDQLGLSLRGTIFRRDASRVESSNTGVELSRRGPNPVKADNYNLGG
KLFWQLNTQSTLWLDGDIANQKYDNSANQLGTIGARGGYEDTLRYQRRKITLGNDNRLDFGTWNSSLSYNQTENIGRLIT
NASVPQGSGLAGEKRLLKNTNIILDSKLVAPLGDNHMVTLGGQYWNAIMKDGIVLANNGDEFAQDAWSLFSEDEWRLLDS
LALTYGARYEYQTTFGGHISPRAYLVWDAQDNWTVKGGVSTGYKTPTLAQLHNGISGVTGQGTITTIGNPKLEPESSVNT
EVGVYYENETGFGANVTLFHNRFRNKINSVSIDNTTSTYTNVGKAITQGIEVASTIPLWSDDWMLGINYTFTDSEQKDGN
NKGARLTNTPKNMVNARLNWNINEQLSTWLKAEYRSKTARFTQNYANLSAANKVVYNNLGSEFKPFSVLNLGVAYKVTKD
VTLNGAVNNLLDKDFTRTHIFAVGNGTTTAGDYFTSSQSTAGYVVPGRNYWVSVNVNF

Sequences:

>Translated_698_residues
MSNKTIAFALVVASSAPVIAADNDNIMVVTASGYEQKIREAAASISVISQNELRQRNYNDLAQALSDVEGVDVNSSTGKT
GGLDISIRGMPSAYTLILVDGIRQNGTSDVTPNGFGAMNTSFMPPLSAIERIEVIRGPMSTLYGSDAIGGVVNIITKKIT
KAWASSATLEHTFQENTAFGDSSKFSFYSSGPAVEDQLGLSLRGTIFRRDASRVESSNTGVELSRRGPNPVKADNYNLGG
KLFWQLNTQSTLWLDGDIANQKYDNSANQLGTIGARGGYEDTLRYQRRKITLGNDNRLDFGTWNSSLSYNQTENIGRLIT
NASVPQGSGLAGEKRLLKNTNIILDSKLVAPLGDNHMVTLGGQYWNAIMKDGIVLANNGDEFAQDAWSLFSEDEWRLLDS
LALTYGARYEYQTTFGGHISPRAYLVWDAQDNWTVKGGVSTGYKTPTLAQLHNGISGVTGQGTITTIGNPKLEPESSVNT
EVGVYYENETGFGANVTLFHNRFRNKINSVSIDNTTSTYTNVGKAITQGIEVASTIPLWSDDWMLGINYTFTDSEQKDGN
NKGARLTNTPKNMVNARLNWNINEQLSTWLKAEYRSKTARFTQNYANLSAANKVVYNNLGSEFKPFSVLNLGVAYKVTKD
VTLNGAVNNLLDKDFTRTHIFAVGNGTTTAGDYFTSSQSTAGYVVPGRNYWVSVNVNF
>Mature_697_residues
SNKTIAFALVVASSAPVIAADNDNIMVVTASGYEQKIREAAASISVISQNELRQRNYNDLAQALSDVEGVDVNSSTGKTG
GLDISIRGMPSAYTLILVDGIRQNGTSDVTPNGFGAMNTSFMPPLSAIERIEVIRGPMSTLYGSDAIGGVVNIITKKITK
AWASSATLEHTFQENTAFGDSSKFSFYSSGPAVEDQLGLSLRGTIFRRDASRVESSNTGVELSRRGPNPVKADNYNLGGK
LFWQLNTQSTLWLDGDIANQKYDNSANQLGTIGARGGYEDTLRYQRRKITLGNDNRLDFGTWNSSLSYNQTENIGRLITN
ASVPQGSGLAGEKRLLKNTNIILDSKLVAPLGDNHMVTLGGQYWNAIMKDGIVLANNGDEFAQDAWSLFSEDEWRLLDSL
ALTYGARYEYQTTFGGHISPRAYLVWDAQDNWTVKGGVSTGYKTPTLAQLHNGISGVTGQGTITTIGNPKLEPESSVNTE
VGVYYENETGFGANVTLFHNRFRNKINSVSIDNTTSTYTNVGKAITQGIEVASTIPLWSDDWMLGINYTFTDSEQKDGNN
KGARLTNTPKNMVNARLNWNINEQLSTWLKAEYRSKTARFTQNYANLSAANKVVYNNLGSEFKPFSVLNLGVAYKVTKDV
TLNGAVNNLLDKDFTRTHIFAVGNGTTTAGDYFTSSQSTAGYVVPGRNYWVSVNVNF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=686, Percent_Identity=33.3819241982507, Blast_Score=310, Evalue=3e-85,
Organism=Escherichia coli, GI1786798, Length=784, Percent_Identity=28.1887755102041, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1790405, Length=194, Percent_Identity=28.8659793814433, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787723, Length=157, Percent_Identity=33.1210191082803, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76102; Mature: 75971

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKTIAFALVVASSAPVIAADNDNIMVVTASGYEQKIREAAASISVISQNELRQRNYND
CCCCEEEEEEEEECCCCEEEECCCCEEEEECCCHHHHHHHHHHHEEEECHHHHHHCCHHH
LAQALSDVEGVDVNSSTGKTGGLDISIRGMPSAYTLILVDGIRQNGTSDVTPNGFGAMNT
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
SFMPPLSAIERIEVIRGPMSTLYGSDAIGGVVNIITKKITKAWASSATLEHTFQENTAFG
CCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
DSSKFSFYSSGPAVEDQLGLSLRGTIFRRDASRVESSNTGVELSRRGPNPVKADNYNLGG
CCCCEEEECCCCCCHHHCCCEEECEEEECCHHHHCCCCCCEEEECCCCCCCCCCCCCCCC
KLFWQLNTQSTLWLDGDIANQKYDNSANQLGTIGARGGYEDTLRYQRRKITLGNDNRLDF
EEEEEECCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHEEEEECCCCCEEE
GTWNSSLSYNQTENIGRLITNASVPQGSGLAGEKRLLKNTNIILDSKLVAPLGDNHMVTL
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEECEEECCCCCCCEEEE
GGQYWNAIMKDGIVLANNGDEFAQDAWSLFSEDEWRLLDSLALTYGARYEYQTTFGGHIS
CHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCC
PRAYLVWDAQDNWTVKGGVSTGYKTPTLAQLHNGISGVTGQGTITTIGNPKLEPESSVNT
CCEEEEEECCCCEEEECCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCC
EVGVYYENETGFGANVTLFHNRFRNKINSVSIDNTTSTYTNVGKAITQGIEVASTIPLWS
EEEEEEECCCCCCCEEEEEHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCHHHEECCCCC
DDWMLGINYTFTDSEQKDGNNKGARLTNTPKNMVNARLNWNINEQLSTWLKAEYRSKTAR
CCEEEEEEEEECCCCCCCCCCCCCEECCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHH
FTQNYANLSAANKVVYNNLGSEFKPFSVLNLGVAYKVTKDVTLNGAVNNLLDKDFTRTHI
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECEEECCHHHHHHCCCCCEEEE
FAVGNGTTTAGDYFTSSQSTAGYVVPGRNYWVSVNVNF
EEECCCCCCCCCEEECCCCCCEEEECCCCEEEEEEECC
>Mature Secondary Structure 
SNKTIAFALVVASSAPVIAADNDNIMVVTASGYEQKIREAAASISVISQNELRQRNYND
CCCEEEEEEEEECCCCEEEECCCCEEEEECCCHHHHHHHHHHHEEEECHHHHHHCCHHH
LAQALSDVEGVDVNSSTGKTGGLDISIRGMPSAYTLILVDGIRQNGTSDVTPNGFGAMNT
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
SFMPPLSAIERIEVIRGPMSTLYGSDAIGGVVNIITKKITKAWASSATLEHTFQENTAFG
CCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
DSSKFSFYSSGPAVEDQLGLSLRGTIFRRDASRVESSNTGVELSRRGPNPVKADNYNLGG
CCCCEEEECCCCCCHHHCCCEEECEEEECCHHHHCCCCCCEEEECCCCCCCCCCCCCCCC
KLFWQLNTQSTLWLDGDIANQKYDNSANQLGTIGARGGYEDTLRYQRRKITLGNDNRLDF
EEEEEECCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHEEEEECCCCCEEE
GTWNSSLSYNQTENIGRLITNASVPQGSGLAGEKRLLKNTNIILDSKLVAPLGDNHMVTL
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEECEEECCCCCCCEEEE
GGQYWNAIMKDGIVLANNGDEFAQDAWSLFSEDEWRLLDSLALTYGARYEYQTTFGGHIS
CHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCC
PRAYLVWDAQDNWTVKGGVSTGYKTPTLAQLHNGISGVTGQGTITTIGNPKLEPESSVNT
CCEEEEEECCCCEEEECCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCC
EVGVYYENETGFGANVTLFHNRFRNKINSVSIDNTTSTYTNVGKAITQGIEVASTIPLWS
EEEEEEECCCCCCCEEEEEHHHHHHHHCCEEECCCCCHHHHHHHHHHHCCHHHEECCCCC
DDWMLGINYTFTDSEQKDGNNKGARLTNTPKNMVNARLNWNINEQLSTWLKAEYRSKTAR
CCEEEEEEEEECCCCCCCCCCCCCEECCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHH
FTQNYANLSAANKVVYNNLGSEFKPFSVLNLGVAYKVTKDVTLNGAVNNLLDKDFTRTHI
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECEEECCHHHHHHCCCCCEEEE
FAVGNGTTTAGDYFTSSQSTAGYVVPGRNYWVSVNVNF
EEECCCCCCCCCEEECCCCCCEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]