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The map label for this gene is ail [H]

Identifier: 170024585

GI number: 170024585

Start: 2592582

End: 2593133

Strand: Reverse

Name: ail [H]

Synonym: YPK_2360

Alternate gene names: 170024585

Gene position: 2593133-2592582 (Counterclockwise)

Preceding gene: 170024587

Following gene: 170024584

Centisome position: 55.3

GC content: 37.32

Gene sequence:

>552_bases
ATGAAAAATAAAACCACATTGGCTGCATTTATAACAGCGTTCTTATTAAGCAGTTCAGCGGCCTATGCGGCAGGGGATCG
TACCATCTCATTGGGGTATGCTCAGGGAGATGTAAGACTCGGTGATGGAAATCGAAAAGACATTAGATTGGACGATGATC
TTAAAGGGATTAATGTTAAATATCTCCATAAGTTGAGTGAAATGTTCGGTGCAATAGGCTCTTTTACTTACACGGATTTA
AATTATGATTATCTAAATAATAATGTCAAAATTGGGGATGCATCCTTTGATTATTATTCGCTGATGGTTGGGCCCAGCGT
ACATTTTAATGAGTTTTTCAGCATGTATGCATTATTGGGAATTGGGCATGGGAAAGCGAAAACATCTGTATTAGGTTACG
GTAAAAAAGAGGAGCAAGACTCTTTGGCATATGGTGTTGGGATGCAATTTAATCCACTTAACAATATTGCTATTGATGCT
TCATACGAGTATACAAAACTTAAAGATGCTAATATCGGTACATGGGTTTTAGGCATTGGCTATCGTTTTTAA

Upstream 100 bases:

>100_bases
AAAAATGGAATTTTGTGTTTGTGATGGACTACTGGCTGAATATTAGTGACCAATGCGACGATACCGTAATCTAAGATAAT
AATTTAAGGATAAAAGTTTA

Downstream 100 bases:

>100_bases
TAAAATACTTTCTATATAATAATAACAGCCGTATTAGTTCACTGTGCGGCTGTTTTTTCATCAGTTGCAAAGAGATTCAT
AACGATAAAAAATTGAGTCC

Product: virulence-related outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKNKTTLAAFITAFLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGKAKTSVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYTKLKDANIGTWVLGIGYRF

Sequences:

>Translated_183_residues
MKNKTTLAAFITAFLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGKAKTSVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYTKLKDANIGTWVLGIGYRF
>Mature_183_residues
MKNKTTLAAFITAFLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGKAKTSVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYTKLKDANIGTWVLGIGYRF

Specific function: Promotes the invasion of pathogenic bacteria into eukaryotic cells by an unknown mechanism [H]

COG id: COG3637

COG function: function code M; Opacity protein and related surface antigens

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ail/ompX/pagC/lom family [H]

Homologues:

Organism=Escherichia coli, GI1787034, Length=190, Percent_Identity=34.2105263157895, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000758
- InterPro:   IPR011250 [H]

Pfam domain/function: PF06316 Ail_Lom [H]

EC number: NA

Molecular weight: Translated: 20188; Mature: 20188

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00695 ENT_VIR_OMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKTTLAAFITAFLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVK
CCCCHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCEEECCCCCCCEEECCCCCCCCHH
YLHKLSEMFGAIGSFTYTDLNYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLG
HHHHHHHHHHHHCCEEEECCCHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHH
IGHGKAKTSVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDASYEYTKLKDANIGTWVLGIG
CCCCCCCCEEECCCCCCCCCCEEEECCCEECCCCCEEEECCCCEEEECCCCCCEEEEEEC
YRF
CCC
>Mature Secondary Structure
MKNKTTLAAFITAFLLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVK
CCCCHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCEEECCCCCCCEEECCCCCCCCHH
YLHKLSEMFGAIGSFTYTDLNYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLG
HHHHHHHHHHHHCCEEEECCCHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHH
IGHGKAKTSVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDASYEYTKLKDANIGTWVLGIG
CCCCCCCCEEECCCCCCCCCCEEEECCCEECCCCCEEEECCCCEEEECCCCCCEEEEEEC
YRF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1688838 [H]