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The map label for this gene is 170023518

Identifier: 170023518

GI number: 170023518

Start: 1400196

End: 1401218

Strand: Direct

Name: 170023518

Synonym: YPK_1272

Alternate gene names: NA

Gene position: 1400196-1401218 (Clockwise)

Preceding gene: 170023517

Following gene: 170023520

Centisome position: 29.86

GC content: 50.93

Gene sequence:

>1023_bases
ATGTCAGTAGTTATTGCTCCGATTCCACGGCCCAAACAGCGACATTGGCTGATCAATTTATGGCCTCTATTGTTGTTCTT
ACTCATATTGGCTAGCGCTGGGTATGTCTCCTGGCTTTATTGGCCAGAATTGCTGTTTAAAACAGTAGCCTGGCAAAAAA
GTGTGCATCAGCAAATGGCCCAACTGTTGCAGCAAGTTAAAGCCGAACCGCATCAGGCGGGGTGGGTGCTGATGTTGTTT
AGCCTGATTTATGGCGTGTTACATGCTGTAGGGCCGGGCCACGGTAAAGTGGTGATTGTGACGTATCTGGCAACCCACCC
GGCGCGGTTAAAAAGCAGCCTGAAACTGACTTTTGCCGCTTCAATATTGCAAGGTAGCGTAGCGATTCTACTGGTAACTT
TGTTACTTGGGGTATGGCAGCTCTCTTCACGGTATCTGCATCAAAGCAGTTTTTGGCTAGAAAAAGGCAGTTTTCTATTG
GTTATTGGGTTGGGGATGTTGCTCTGTTTCCGGGCGGTAAAGCGGATCTATCGACAAATTAACGCCTTAAAACCACAGAA
AATGACTTTTCAGCAGATTCAGCCATTACCGGCTAACCATGTGCACAGCGACAACTGCGGCTGTGGGCACCGTCATCTGC
CCAGTGATAAAGAGCTACAAGCCGGTGGCGATTGGCGCACCCGTTTGACGATTGTATTGGCGATGGGGATGCGCCCTTGC
TCCGGTGCGATTATGGTGTTGCTGTTTTCCAAGGTGATTGGCGTTTACTGGTGGGGGATTTTGTCGGCGATGGCGATGGC
TTTAGGGACGTCGCTGACTATCTCGCTGTTGGCACTGTTCGTCCATTATGCACGGCGCTTGGCGGTATATTTAAGCCGTA
AACGCGCCCCTGCCGCTTGGGGAGAGATTGCCTGGGCCACGCTGGCATTAACCGGGGGAATTATTCTGCTGTTCGCGGGG
GTTCTGTTTTATTTGTCCAGTCAGCCGGAGATGGTTGGGGCTGTTCGTCCATTTGGTCGCTGA

Upstream 100 bases:

>100_bases
ACGCATCGCTACAGGCTTATGCGCTGTCATTGGATAAAAGTGATTCACCAGGAGACGATATGGAACTTGGAAAACAATTT
GCCCAACAAGTGACGCTTCA

Downstream 100 bases:

>100_bases
TACCCTTCGACCTTGACGCTGCAGAGGGGTTCCCAATAAAAAAAGCCAGTCGGCTAACCCTGACTGGCTTTTTATCTGAA
ACGGCTATTTGCGTGGAATT

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSVVIAPIPRPKQRHWLINLWPLLLFLLILASAGYVSWLYWPELLFKTVAWQKSVHQQMAQLLQQVKAEPHQAGWVLMLF
SLIYGVLHAVGPGHGKVVIVTYLATHPARLKSSLKLTFAASILQGSVAILLVTLLLGVWQLSSRYLHQSSFWLEKGSFLL
VIGLGMLLCFRAVKRIYRQINALKPQKMTFQQIQPLPANHVHSDNCGCGHRHLPSDKELQAGGDWRTRLTIVLAMGMRPC
SGAIMVLLFSKVIGVYWWGILSAMAMALGTSLTISLLALFVHYARRLAVYLSRKRAPAAWGEIAWATLALTGGIILLFAG
VLFYLSSQPEMVGAVRPFGR

Sequences:

>Translated_340_residues
MSVVIAPIPRPKQRHWLINLWPLLLFLLILASAGYVSWLYWPELLFKTVAWQKSVHQQMAQLLQQVKAEPHQAGWVLMLF
SLIYGVLHAVGPGHGKVVIVTYLATHPARLKSSLKLTFAASILQGSVAILLVTLLLGVWQLSSRYLHQSSFWLEKGSFLL
VIGLGMLLCFRAVKRIYRQINALKPQKMTFQQIQPLPANHVHSDNCGCGHRHLPSDKELQAGGDWRTRLTIVLAMGMRPC
SGAIMVLLFSKVIGVYWWGILSAMAMALGTSLTISLLALFVHYARRLAVYLSRKRAPAAWGEIAWATLALTGGIILLFAG
VLFYLSSQPEMVGAVRPFGR
>Mature_339_residues
SVVIAPIPRPKQRHWLINLWPLLLFLLILASAGYVSWLYWPELLFKTVAWQKSVHQQMAQLLQQVKAEPHQAGWVLMLFS
LIYGVLHAVGPGHGKVVIVTYLATHPARLKSSLKLTFAASILQGSVAILLVTLLLGVWQLSSRYLHQSSFWLEKGSFLLV
IGLGMLLCFRAVKRIYRQINALKPQKMTFQQIQPLPANHVHSDNCGCGHRHLPSDKELQAGGDWRTRLTIVLAMGMRPCS
GAIMVLLFSKVIGVYWWGILSAMAMALGTSLTISLLALFVHYARRLAVYLSRKRAPAAWGEIAWATLALTGGIILLFAGV
LFYLSSQPEMVGAVRPFGR

Specific function: Efflux system for nickel and cobalt (Potential) [H]

COG id: COG2215

COG function: function code R; ABC-type uncharacterized transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37894; Mature: 37763

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVIAPIPRPKQRHWLINLWPLLLFLLILASAGYVSWLYWPELLFKTVAWQKSVHQQMA
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLQQVKAEPHQAGWVLMLFSLIYGVLHAVGPGHGKVVIVTYLATHPARLKSSLKLTFAA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
SILQGSVAILLVTLLLGVWQLSSRYLHQSSFWLEKGSFLLVIGLGMLLCFRAVKRIYRQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
NALKPQKMTFQQIQPLPANHVHSDNCGCGHRHLPSDKELQAGGDWRTRLTIVLAMGMRPC
HCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
SGAIMVLLFSKVIGVYWWGILSAMAMALGTSLTISLLALFVHYARRLAVYLSRKRAPAAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GEIAWATLALTGGIILLFAGVLFYLSSQPEMVGAVRPFGR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SVVIAPIPRPKQRHWLINLWPLLLFLLILASAGYVSWLYWPELLFKTVAWQKSVHQQMA
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLQQVKAEPHQAGWVLMLFSLIYGVLHAVGPGHGKVVIVTYLATHPARLKSSLKLTFAA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
SILQGSVAILLVTLLLGVWQLSSRYLHQSSFWLEKGSFLLVIGLGMLLCFRAVKRIYRQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
NALKPQKMTFQQIQPLPANHVHSDNCGCGHRHLPSDKELQAGGDWRTRLTIVLAMGMRPC
HCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
SGAIMVLLFSKVIGVYWWGILSAMAMALGTSLTISLLALFVHYARRLAVYLSRKRAPAAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GEIAWATLALTGGIILLFAGVLFYLSSQPEMVGAVRPFGR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]