Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 170023355

GI number: 170023355

Start: 1248005

End: 1248769

Strand: Direct

Name: dnaQ [H]

Synonym: YPK_1109

Alternate gene names: 170023355

Gene position: 1248005-1248769 (Clockwise)

Preceding gene: 170023353

Following gene: 170023357

Centisome position: 26.61

GC content: 46.01

Gene sequence:

>765_bases
ATGATCATTACACCGACCAGACAGATTGTTCTGGATACTGAAACTACCGGTATGAATAAGCTTGGCGTTCATTATGAAGG
CCATCGTATTATTGAAATCGGTGCCGTTGAAGTTATCAACCGCCGCCTGACCGGCAGAAATTTCCATGTATATGTGAAGC
CCGACCGTTTGGTTGATCCAGAAGCTTACGGGGTTCACGGGATCAGCGATGAGTTTTTGGCTGACAAGCCAACATTTGCT
GATATTACGCCGGAGTTTTTAGATTTTATCCGTGGCGCTGAATTAGTCATCCATAATGCTGCGTTTGATATCGGCTTTAT
GGATTACGAGTTCCGGATGTTGCAGCAAGATATTCCGAAAACGGAGACCTTCTGTACTATCACTGATAGCCTGTTGATGG
CTCGCCGCTTATTTCCCGGTAAGCGGAATAACCTTGATGCCCTGTGTGATCGCTATCAGATAGATAATACCAAACGAACC
TTGCACGGTGCGTTACTTGATGCCGAGATTCTGGCTGAAGTTTATTTAGCAATGACTGGCGGGCAGACATCGCTAACTTT
CTCCATGGAAGGCGAAGTGTCGCAGAATAACGCGTCTGAAGATATTCAACGCATTACTCGCCCAGCATCGGCATTGAAAA
TTATCTATGCTACCGAGGATGAATTGGCTAATCATGAATCCCGTTTGGATTTTGTGATGAAAAAGGGCGGCAGTTGCCTG
TGGCGGATGCCGCTTGAGGCAGAAGAAGAGACAAAAGCAGAATAA

Upstream 100 bases:

>100_bases
CATCGGTGAAAATTTCTACCTGTTTAGTCATCTCTGGTAGACTCTTCCTATCTGTTTAAACGTCAAGTCTGACATAAACG
AGCGCTGTGAGCACTGCAAT

Downstream 100 bases:

>100_bases
AAGCACACCCAGATGAAAAACTGTGCAAATGGCTTATTTCACTGGAAAAAGTGTTGACGCCATTCCGTTCTAACCGTACT
ATCCGTCTCGTTCTTAACCG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MIITPTRQIVLDTETTGMNKLGVHYEGHRIIEIGAVEVINRRLTGRNFHVYVKPDRLVDPEAYGVHGISDEFLADKPTFA
DITPEFLDFIRGAELVIHNAAFDIGFMDYEFRMLQQDIPKTETFCTITDSLLMARRLFPGKRNNLDALCDRYQIDNTKRT
LHGALLDAEILAEVYLAMTGGQTSLTFSMEGEVSQNNASEDIQRITRPASALKIIYATEDELANHESRLDFVMKKGGSCL
WRMPLEAEEETKAE

Sequences:

>Translated_254_residues
MIITPTRQIVLDTETTGMNKLGVHYEGHRIIEIGAVEVINRRLTGRNFHVYVKPDRLVDPEAYGVHGISDEFLADKPTFA
DITPEFLDFIRGAELVIHNAAFDIGFMDYEFRMLQQDIPKTETFCTITDSLLMARRLFPGKRNNLDALCDRYQIDNTKRT
LHGALLDAEILAEVYLAMTGGQTSLTFSMEGEVSQNNASEDIQRITRPASALKIIYATEDELANHESRLDFVMKKGGSCL
WRMPLEAEEETKAE
>Mature_254_residues
MIITPTRQIVLDTETTGMNKLGVHYEGHRIIEIGAVEVINRRLTGRNFHVYVKPDRLVDPEAYGVHGISDEFLADKPTFA
DITPEFLDFIRGAELVIHNAAFDIGFMDYEFRMLQQDIPKTETFCTITDSLLMARRLFPGKRNNLDALCDRYQIDNTKRT
LHGALLDAEILAEVYLAMTGGQTSLTFSMEGEVSQNNASEDIQRITRPASALKIIYATEDELANHESRLDFVMKKGGSCL
WRMPLEAEEETKAE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=242, Percent_Identity=74.7933884297521, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1788149, Length=181, Percent_Identity=32.5966850828729, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 28762; Mature: 28762

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITPTRQIVLDTETTGMNKLGVHYEGHRIIEIGAVEVINRRLTGRNFHVYVKPDRLVDP
CEECCCCEEEEECCCCCCCCCCEEECCCEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCC
EAYGVHGISDEFLADKPTFADITPEFLDFIRGAELVIHNAAFDIGFMDYEFRMLQQDIPK
CCCCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECEEECCCCHHHHHHHHHHCCC
TETFCTITDSLLMARRLFPGKRNNLDALCDRYQIDNTKRTLHGALLDAEILAEVYLAMTG
CCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEC
GQTSLTFSMEGEVSQNNASEDIQRITRPASALKIIYATEDELANHESRLDFVMKKGGSCL
CCEEEEEEECCCCCCCCHHHHHHHHHCCHHHEEEEEECCHHHHCHHHHHHHHHHCCCCEE
WRMPLEAEEETKAE
EECCCCCCHHCCCC
>Mature Secondary Structure
MIITPTRQIVLDTETTGMNKLGVHYEGHRIIEIGAVEVINRRLTGRNFHVYVKPDRLVDP
CEECCCCEEEEECCCCCCCCCCEEECCCEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCC
EAYGVHGISDEFLADKPTFADITPEFLDFIRGAELVIHNAAFDIGFMDYEFRMLQQDIPK
CCCCCCCCCHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECEEECCCCHHHHHHHHHHCCC
TETFCTITDSLLMARRLFPGKRNNLDALCDRYQIDNTKRTLHGALLDAEILAEVYLAMTG
CCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEC
GQTSLTFSMEGEVSQNNASEDIQRITRPASALKIIYATEDELANHESRLDFVMKKGGSCL
CCEEEEEEECCCCCCCCHHHHHHHHHCCHHHEEEEEECCHHHHCHHHHHHHHHHCCCCEE
WRMPLEAEEETKAE
EECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]