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The map label for this gene is yqfA [H]

Identifier: 170023122

GI number: 170023122

Start: 1000891

End: 1001592

Strand: Direct

Name: yqfA [H]

Synonym: YPK_0873

Alternate gene names: 170023122

Gene position: 1000891-1001592 (Clockwise)

Preceding gene: 170023121

Following gene: 170023123

Centisome position: 21.34

GC content: 50.14

Gene sequence:

>702_bases
TTGAAGAATAAATCAGGGACACAACCTCTCTTTGCAACACCATCCGTACCCGCCGCACAAACGGCCACCCCAACCCCGGT
TTACCCGTGGGCTGAAGAGCTGGCGAACAGCCTCAGCCATGGTATCGGTGTGGTGTTCGGTATTGTGGGGCTGGTATTGC
TACTGGTTCAGGCGGTGAACAGTGGTGCCGATACCAAAGCGCTCACTAGCTATAGTTTGTACGGTAGCAGTATCATTTTG
TTGTTTTTGGCCTCTACGCTGTATCACGCCATTCCACATCGTAGGGCGAAGCTCTGGCTGCAAAAATTTGATCACTGCGC
TATCTACATCTTGATTGCCGGGACTTATACGCCGTTCTTATTAGTAGGGCTAGATTCGCCTCTGGCCAGAGGTTTGATGG
CGGTTATTTGGGGGCTGGCACTCATCGGTGTGATCTTTAAGTTGGCGTTTGCTCATCGTTTTGAAGTGTTGTCACTGGTG
ACCTATCTGACCATGGGGTGGTTATCGCTGATTGTCATTTATCAGCTCGCGGTCAAGCTTGAGATCGGGGGGTTGGCACT
GCTGGCGATAGGGGGCTTGTTATATACGGTTGGGGTGATCTTCTATGCATCGAAACGTATCCGTTTTGGTCATGCTATCT
GGCACGGTTTTGTGTTAGGCGGCAGTGTCTGCCATTTTATGGCGATCTATCTATATGTTTAA

Upstream 100 bases:

>100_bases
ATCACTCTCAGTTAATCTGAGTGCGCTATTTCTGTACAGTAGAATGGCCCATAACCCGTTTACCGGGCGAGATAATAATT
AATATTTAGGATAATCAGTA

Downstream 100 bases:

>100_bases
TACAGACACATGTTTAATACAGACACATATTTAATACAGACACATATTTAATACAGACACATATTTGATGCAGGTATTAG
GTTTGATACGACCATCTATT

Product: hemolysin III family channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKNKSGTQPLFATPSVPAAQTATPTPVYPWAEELANSLSHGIGVVFGIVGLVLLLVQAVNSGADTKALTSYSLYGSSIIL
LFLASTLYHAIPHRRAKLWLQKFDHCAIYILIAGTYTPFLLVGLDSPLARGLMAVIWGLALIGVIFKLAFAHRFEVLSLV
TYLTMGWLSLIVIYQLAVKLEIGGLALLAIGGLLYTVGVIFYASKRIRFGHAIWHGFVLGGSVCHFMAIYLYV

Sequences:

>Translated_233_residues
MKNKSGTQPLFATPSVPAAQTATPTPVYPWAEELANSLSHGIGVVFGIVGLVLLLVQAVNSGADTKALTSYSLYGSSIIL
LFLASTLYHAIPHRRAKLWLQKFDHCAIYILIAGTYTPFLLVGLDSPLARGLMAVIWGLALIGVIFKLAFAHRFEVLSLV
TYLTMGWLSLIVIYQLAVKLEIGGLALLAIGGLLYTVGVIFYASKRIRFGHAIWHGFVLGGSVCHFMAIYLYV
>Mature_233_residues
MKNKSGTQPLFATPSVPAAQTATPTPVYPWAEELANSLSHGIGVVFGIVGLVLLLVQAVNSGADTKALTSYSLYGSSIIL
LFLASTLYHAIPHRRAKLWLQKFDHCAIYILIAGTYTPFLLVGLDSPLARGLMAVIWGLALIGVIFKLAFAHRFEVLSLV
TYLTMGWLSLIVIYQLAVKLEIGGLALLAIGGLLYTVGVIFYASKRIRFGHAIWHGFVLGGSVCHFMAIYLYV

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=229, Percent_Identity=31.0043668122271, Blast_Score=103, Evalue=9e-23,
Organism=Homo sapiens, GI52630445, Length=241, Percent_Identity=31.9502074688797, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI154759277, Length=253, Percent_Identity=28.0632411067194, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789266, Length=206, Percent_Identity=76.6990291262136, Blast_Score=326, Evalue=8e-91,
Organism=Caenorhabditis elegans, GI71996356, Length=211, Percent_Identity=31.7535545023697, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24640324, Length=232, Percent_Identity=29.7413793103448, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 25268; Mature: 25268

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKSGTQPLFATPSVPAAQTATPTPVYPWAEELANSLSHGIGVVFGIVGLVLLLVQAVN
CCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGADTKALTSYSLYGSSIILLFLASTLYHAIPHRRAKLWLQKFDHCAIYILIAGTYTPFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEEEECCCCCEE
LVGLDSPLARGLMAVIWGLALIGVIFKLAFAHRFEVLSLVTYLTMGWLSLIVIYQLAVKL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGGLALLAIGGLLYTVGVIFYASKRIRFGHAIWHGFVLGGSVCHFMAIYLYV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKSGTQPLFATPSVPAAQTATPTPVYPWAEELANSLSHGIGVVFGIVGLVLLLVQAVN
CCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGADTKALTSYSLYGSSIILLFLASTLYHAIPHRRAKLWLQKFDHCAIYILIAGTYTPFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEEEECCCCCEE
LVGLDSPLARGLMAVIWGLALIGVIFKLAFAHRFEVLSLVTYLTMGWLSLIVIYQLAVKL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGGLALLAIGGLLYTVGVIFYASKRIRFGHAIWHGFVLGGSVCHFMAIYLYV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]