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The map label for this gene is apt [H]

Identifier: 170022336

GI number: 170022336

Start: 83291

End: 83839

Strand: Reverse

Name: apt [H]

Synonym: YPK_0074

Alternate gene names: 170022336

Gene position: 83839-83291 (Counterclockwise)

Preceding gene: 170022337

Following gene: 170022335

Centisome position: 1.79

GC content: 37.16

Gene sequence:

>549_bases
GTGTATAAAAATGCTCAGGTAGTGAACTCAGGAAAAGCATTAACCACCGTCAATGAATTTACAGACCAGTTGCCTGCCCT
CAGACCAGCAGTCTTGCTAGAAGTCGCACATAAAGTCATACAAATTATAGATATGGATATCGATAAAATCGTAACAGAAG
AAGATAAAGGTGCTCCCCTCGCTACTGCTGTTTCCTTGTTATCAGGCAAACCATTGGCGATGGCTCGTTGGTATCCATAC
AGTCTTAGTGAGTTAAATAATAATGTTGTAAATATTTCATCTGAATATTTTGAAGGTGTAGTGTACCTCAATGGCATATC
TGCTGGTGATCGTGTCGCTATTATAGATGATACGTTGAGTACAGGGGGTACGGTTATCGCTCTCATTAAAGCAATACAGA
ATTCTGGAGGAATAGTTAAAGATGTTATTTGTGCTGTAGAAAAAATCCAAAACAATGGTAAAAAAAACATATTTACACAA
ACAGGCATTAACGTTAAAACACTAATGAAAATTAGTGTTAAACCTCATGGGGTAGATATCATTGAGTGA

Upstream 100 bases:

>100_bases
CTGGCTTGGATTGGTCAAAAAAAAGGCTATAAAATTAAAATATTTATGCCTGAAGGCATGACTGAAGAACGCAAAGAACA
GATCTATTCATTTAAAGAAC

Downstream 100 bases:

>100_bases
AATTCAAAAATCACATCTCTCCAACAATTACTGGTTAAAAAAACACATTATATAAAATTAATCAGTGAGATAAGGAAGTT
CTATGCATGCTTATAGTGGA

Product: adenine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MYKNAQVVNSGKALTTVNEFTDQLPALRPAVLLEVAHKVIQIIDMDIDKIVTEEDKGAPLATAVSLLSGKPLAMARWYPY
SLSELNNNVVNISSEYFEGVVYLNGISAGDRVAIIDDTLSTGGTVIALIKAIQNSGGIVKDVICAVEKIQNNGKKNIFTQ
TGINVKTLMKISVKPHGVDIIE

Sequences:

>Translated_182_residues
MYKNAQVVNSGKALTTVNEFTDQLPALRPAVLLEVAHKVIQIIDMDIDKIVTEEDKGAPLATAVSLLSGKPLAMARWYPY
SLSELNNNVVNISSEYFEGVVYLNGISAGDRVAIIDDTLSTGGTVIALIKAIQNSGGIVKDVICAVEKIQNNGKKNIFTQ
TGINVKTLMKISVKPHGVDIIE
>Mature_182_residues
MYKNAQVVNSGKALTTVNEFTDQLPALRPAVLLEVAHKVIQIIDMDIDKIVTEEDKGAPLATAVSLLSGKPLAMARWYPY
SLSELNNNVVNISSEYFEGVVYLNGISAGDRVAIIDDTLSTGGTVIALIKAIQNSGGIVKDVICAVEKIQNNGKKNIFTQ
TGINVKTLMKISVKPHGVDIIE

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005764
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.7 [H]

Molecular weight: Translated: 19596; Mature: 19596

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKNAQVVNSGKALTTVNEFTDQLPALRPAVLLEVAHKVIQIIDMDIDKIVTEEDKGAPL
CCCCCEEECCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHH
ATAVSLLSGKPLAMARWYPYSLSELNNNVVNISSEYFEGVVYLNGISAGDRVAIIDDTLS
HHHHHHHCCCCEEEEEECCCCHHHCCCCEEEECHHHHCEEEEEECCCCCCEEEEEECCCC
TGGTVIALIKAIQNSGGIVKDVICAVEKIQNNGKKNIFTQTGINVKTLMKISVKPHGVDI
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCEE
IE
CC
>Mature Secondary Structure
MYKNAQVVNSGKALTTVNEFTDQLPALRPAVLLEVAHKVIQIIDMDIDKIVTEEDKGAPL
CCCCCEEECCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHH
ATAVSLLSGKPLAMARWYPYSLSELNNNVVNISSEYFEGVVYLNGISAGDRVAIIDDTLS
HHHHHHHCCCCEEEEEECCCCHHHCCCCEEEECHHHHCEEEEEECCCCCCEEEEEECCCC
TGGTVIALIKAIQNSGGIVKDVICAVEKIQNNGKKNIFTQTGINVKTLMKISVKPHGVDI
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCEE
IE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA