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The map label for this gene is cysM [H]

Identifier: 170022337

GI number: 170022337

Start: 83832

End: 84155

Strand: Reverse

Name: cysM [H]

Synonym: YPK_0075

Alternate gene names: 170022337

Gene position: 84155-83832 (Counterclockwise)

Preceding gene: 170022360

Following gene: 170022336

Centisome position: 1.79

GC content: 34.26

Gene sequence:

>324_bases
ATGGAACTTAAGGATATTGGTAACACCGAGCTTATTGAGCTAAAAAACTTATCAATAAATAATAATTCTCTTTTTTCTAA
GTGCGAATTCAACAATCCTACAGGTAGCCATAAAGACCGAACATTTCTGCATATCCTCAATATCTTGGAAGAAGAAAATA
AAATAATTCCCGGAATGACATTGATAGACTGCTCAACAGGGAATGGAGGTGCAGCACTGGCTTGGATTGGTCAAAAAAAA
GGCTATAAAATTAAAATATTTATGCCTGAAGGCATGACTGAAGAACGCAAAGAACAGATCTATTCATTTAAAGAACGTGT
ATAA

Upstream 100 bases:

>100_bases
TAGTATTTAAAATAATTCAAAAAAATTAAATTACACATTGATATTTACCCTCCGGGAAATTTATGTTTTATTGTGCACCT
CCATAAAAAAGGAGTGTGTC

Downstream 100 bases:

>100_bases
AAATGCTCAGGTAGTGAACTCAGGAAAAGCATTAACCACCGTCAATGAATTTACAGACCAGTTGCCTGCCCTCAGACCAG
CAGTCTTGCTAGAAGTCGCA

Product: pyridoxal-phosphate dependent protein

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MELKDIGNTELIELKNLSINNNSLFSKCEFNNPTGSHKDRTFLHILNILEEENKIIPGMTLIDCSTGNGGAALAWIGQKK
GYKIKIFMPEGMTEERKEQIYSFKERV

Sequences:

>Translated_107_residues
MELKDIGNTELIELKNLSINNNSLFSKCEFNNPTGSHKDRTFLHILNILEEENKIIPGMTLIDCSTGNGGAALAWIGQKK
GYKIKIFMPEGMTEERKEQIYSFKERV
>Mature_107_residues
MELKDIGNTELIELKNLSINNNSLFSKCEFNNPTGSHKDRTFLHILNILEEENKIIPGMTLIDCSTGNGGAALAWIGQKK
GYKIKIFMPEGMTEERKEQIYSFKERV

Specific function: Two cysteine synthase enzymes are found. Both catalyze the same reaction. Cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product [H]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=97, Percent_Identity=36.0824742268041, Blast_Score=66, Evalue=6e-12,
Organism=Homo sapiens, GI295821200, Length=97, Percent_Identity=36.0824742268041, Blast_Score=66, Evalue=6e-12,
Organism=Homo sapiens, GI4557415, Length=97, Percent_Identity=36.0824742268041, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI2367138, Length=101, Percent_Identity=40.5940594059406, Blast_Score=84, Evalue=2e-18,
Organism=Escherichia coli, GI1788754, Length=98, Percent_Identity=33.6734693877551, Blast_Score=64, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32566674, Length=104, Percent_Identity=37.5, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562970, Length=104, Percent_Identity=37.5, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115535073, Length=104, Percent_Identity=35.5769230769231, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535051, Length=104, Percent_Identity=36.5384615384615, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561720, Length=104, Percent_Identity=35.5769230769231, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147552, Length=100, Percent_Identity=35, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643623, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129101, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 12178; Mature: 12178

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKDIGNTELIELKNLSINNNSLFSKCEFNNPTGSHKDRTFLHILNILEEENKIIPGMT
CCCCCCCCCEEEEEECCEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEE
LIDCSTGNGGAALAWIGQKKGYKIKIFMPEGMTEERKEQIYSFKERV
EEEECCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MELKDIGNTELIELKNLSINNNSLFSKCEFNNPTGSHKDRTFLHILNILEEENKIIPGMT
CCCCCCCCCEEEEEECCEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEE
LIDCSTGNGGAALAWIGQKKGYKIKIFMPEGMTEERKEQIYSFKERV
EEEECCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503 [H]