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The map label for this gene is yhdG [H]

Identifier: 169630909

GI number: 169630909

Start: 3875113

End: 3876576

Strand: Reverse

Name: yhdG [H]

Synonym: MAB_3829c

Alternate gene names: 169630909

Gene position: 3876576-3875113 (Counterclockwise)

Preceding gene: 169630910

Following gene: 169630908

Centisome position: 76.5

GC content: 62.02

Gene sequence:

>1464_bases
ATGTCAACTTCCGATGATGCCGCCAGCTCGCCCCCGGAAGCATCCCATGATCACGCTGGCGTCCAATCTCATCTTGAGGG
CGCGGACTATCTCGCGCGACGGCAGCTGAGGTCGGGCACCGCGGGCTGGGTATTACTGGCAGGCCTGGGAGTCAGCTATG
TCATCTCCGGTGACTACGCGGGCTGGAACACCGGCCTGAGCAAGGGTGGGTTCGGTGGTCTGGCCATCGCGGCGGTCATC
ATCGCCGCGATGTATCTGTCGATGGTGCTGAGCATGGCGGAGATGTCGTCCGCGTTGCCCACGGCCGGCGGGGGCTACAC
CTTTGCCCGGAGGGCGCTGGGCCCGTGGGGTGGATTCGCCACTGGGACGGCGATTCTCATTGAGTATGCCATCGCTCCGG
CCGCCATCGCGACCTTCATCGGAAGCTATGTCGAATCGCTGCACCTGCCCGGCCTCGCCGATGGGTGGTGGATCTACCTG
GCGGTTTACGCAGTCTTTATCGGTATCCATCTCAGTGGAGCCGGTGAGGCACTTCGGACGATGTTCATCATCACCGGGGT
GGCGCTGGTTGGTCTGGTCATCTTCACGATCGGGGCCGTTGGCCGATTCGACGTGCACAACCTCACCAATATCCCTGTCG
ACGAAAGTGCGAGGGGTGCATCGGCGTTCCTGCCGTACGGGTACTTGGGCATCTGGGCGGCGGTGCCGTTCGCCATCTGG
CTGTTCCTGGCGATCGAAGGTGTTCCGCTCGCGGCAGAGGAGGCTCGTGAACCGGCCAAGAACATCCCGCGTGGAATTCT
GATGGCGATGCTGGTGCTCGTCATCACCGGCACGGCCGTGTTGTTACTGGTTCCGGGGGTCGGGGGAGCCCAGGAAATGG
GGGAGTCGGGAAACCCTCTGGTGGAAGCGCTGGGTACGGCCACGGTCGCCAAGGTGGTCAACTACATCGGGCTGTCCGGG
CTCATCGCCAGTTTCTTCTCGATTGTCTACGCCTACAGCCGGCAGACCTTCGCGTTGTCCCGGGCTGGATATCTGCCGAC
CGGACTGTCGGTCACCAACGGTCGCAAGGCGCCTGTGCTGGCGCTGATCGTGCCGGGAATCGTCGGGTTCCTGTTGTCGC
TCACCGGTGAAGGCGCCATGTTGCTCAACATGGCGGTCTTCGGTGCTGCCCTGAGTTATGTGCTCATGATGGTGAGCCAC
ATCGTGCTGCGCATTCGCGAACCGGAGATGGAGCGGCCGTACCGGACACCCGGTGGCATCGCGACAAGTGGTTTCGCGCT
GGTGATCGCCTGTGTTGCTGTCGTGGCAACATTCATTGTCGATACCACCGCGGCGTTCGCCACGTTTGGTGTGTTTGTGC
TGTTTATGGCGTACTTTGGGTTGTATAGCCGACACCATTTGGTTGCGAACTCGCCAGACGAGGAGTTCGCGGCGCTTGCC
GAAGCCGAGAACGAACTGAAATAG

Upstream 100 bases:

>100_bases
GATCGGACACCGGGCCGCGCAGTTTGTTGCGTGGTCGTAACGGAATATGAATCTCGTCGTCTAACCCACGCGTGCAGACC
ATCGGTCGCACAATTGGACG

Downstream 100 bases:

>100_bases
GCACATTATGAGCACTTTTCGTCATATCGCCGGACCGGTGACCTACCAGTTCGGATCGCTCGCGGAAGTTCTCGCCAAGG
CCTCACCGCCACGGTCCGGC

Product: ethanolamine permease

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSTSDDAASSPPEASHDHAGVQSHLEGADYLARRQLRSGTAGWVLLAGLGVSYVISGDYAGWNTGLSKGGFGGLAIAAVI
IAAMYLSMVLSMAEMSSALPTAGGGYTFARRALGPWGGFATGTAILIEYAIAPAAIATFIGSYVESLHLPGLADGWWIYL
AVYAVFIGIHLSGAGEALRTMFIITGVALVGLVIFTIGAVGRFDVHNLTNIPVDESARGASAFLPYGYLGIWAAVPFAIW
LFLAIEGVPLAAEEAREPAKNIPRGILMAMLVLVITGTAVLLLVPGVGGAQEMGESGNPLVEALGTATVAKVVNYIGLSG
LIASFFSIVYAYSRQTFALSRAGYLPTGLSVTNGRKAPVLALIVPGIVGFLLSLTGEGAMLLNMAVFGAALSYVLMMVSH
IVLRIREPEMERPYRTPGGIATSGFALVIACVAVVATFIVDTTAAFATFGVFVLFMAYFGLYSRHHLVANSPDEEFAALA
EAENELK

Sequences:

>Translated_487_residues
MSTSDDAASSPPEASHDHAGVQSHLEGADYLARRQLRSGTAGWVLLAGLGVSYVISGDYAGWNTGLSKGGFGGLAIAAVI
IAAMYLSMVLSMAEMSSALPTAGGGYTFARRALGPWGGFATGTAILIEYAIAPAAIATFIGSYVESLHLPGLADGWWIYL
AVYAVFIGIHLSGAGEALRTMFIITGVALVGLVIFTIGAVGRFDVHNLTNIPVDESARGASAFLPYGYLGIWAAVPFAIW
LFLAIEGVPLAAEEAREPAKNIPRGILMAMLVLVITGTAVLLLVPGVGGAQEMGESGNPLVEALGTATVAKVVNYIGLSG
LIASFFSIVYAYSRQTFALSRAGYLPTGLSVTNGRKAPVLALIVPGIVGFLLSLTGEGAMLLNMAVFGAALSYVLMMVSH
IVLRIREPEMERPYRTPGGIATSGFALVIACVAVVATFIVDTTAAFATFGVFVLFMAYFGLYSRHHLVANSPDEEFAALA
EAENELK
>Mature_486_residues
STSDDAASSPPEASHDHAGVQSHLEGADYLARRQLRSGTAGWVLLAGLGVSYVISGDYAGWNTGLSKGGFGGLAIAAVII
AAMYLSMVLSMAEMSSALPTAGGGYTFARRALGPWGGFATGTAILIEYAIAPAAIATFIGSYVESLHLPGLADGWWIYLA
VYAVFIGIHLSGAGEALRTMFIITGVALVGLVIFTIGAVGRFDVHNLTNIPVDESARGASAFLPYGYLGIWAAVPFAIWL
FLAIEGVPLAAEEAREPAKNIPRGILMAMLVLVITGTAVLLLVPGVGGAQEMGESGNPLVEALGTATVAKVVNYIGLSGL
IASFFSIVYAYSRQTFALSRAGYLPTGLSVTNGRKAPVLALIVPGIVGFLLSLTGEGAMLLNMAVFGAALSYVLMMVSHI
VLRIREPEMERPYRTPGGIATSGFALVIACVAVVATFIVDTTAAFATFGVFVLFMAYFGLYSRHHLVANSPDEEFAALAE
AENELK

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=416, Percent_Identity=25.2403846153846, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI114326544, Length=446, Percent_Identity=23.9910313901345, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI114326550, Length=446, Percent_Identity=23.9910313901345, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI258614005, Length=417, Percent_Identity=25.1798561151079, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI258614003, Length=417, Percent_Identity=25.1798561151079, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI7657683, Length=345, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786302, Length=337, Percent_Identity=27.893175074184, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786602, Length=348, Percent_Identity=23.2758620689655, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786789, Length=368, Percent_Identity=24.4565217391304, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790653, Length=362, Percent_Identity=23.4806629834254, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081708, Length=405, Percent_Identity=25.4320987654321, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI2367353, Length=314, Percent_Identity=26.4331210191083, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=349, Percent_Identity=24.0687679083095, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533459, Length=343, Percent_Identity=24.198250728863, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221512776, Length=395, Percent_Identity=27.5949367088608, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668806, Length=349, Percent_Identity=23.4957020057307, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21356285, Length=349, Percent_Identity=23.4957020057307, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24668802, Length=349, Percent_Identity=23.4957020057307, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24666159, Length=395, Percent_Identity=27.5949367088608, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24667468, Length=388, Percent_Identity=26.8041237113402, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50787; Mature: 50655

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSDDAASSPPEASHDHAGVQSHLEGADYLARRQLRSGTAGWVLLAGLGVSYVISGDYA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCC
GWNTGLSKGGFGGLAIAAVIIAAMYLSMVLSMAEMSSALPTAGGGYTFARRALGPWGGFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHH
TGTAILIEYAIAPAAIATFIGSYVESLHLPGLADGWWIYLAVYAVFIGIHLSGAGEALRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
MFIITGVALVGLVIFTIGAVGRFDVHNLTNIPVDESARGASAFLPYGYLGIWAAVPFAIW
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFLAIEGVPLAAEEAREPAKNIPRGILMAMLVLVITGTAVLLLVPGVGGAQEMGESGNPL
HHHHHCCCCCCHHHHHCHHHHCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHCCCCCCHH
VEALGTATVAKVVNYIGLSGLIASFFSIVYAYSRQTFALSRAGYLPTGLSVTNGRKAPVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHH
ALIVPGIVGFLLSLTGEGAMLLNMAVFGAALSYVLMMVSHIVLRIREPEMERPYRTPGGI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ATSGFALVIACVAVVATFIVDTTAAFATFGVFVLFMAYFGLYSRHHLVANSPDEEFAALA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EAENELK
HHHHCCC
>Mature Secondary Structure 
STSDDAASSPPEASHDHAGVQSHLEGADYLARRQLRSGTAGWVLLAGLGVSYVISGDYA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCC
GWNTGLSKGGFGGLAIAAVIIAAMYLSMVLSMAEMSSALPTAGGGYTFARRALGPWGGFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHH
TGTAILIEYAIAPAAIATFIGSYVESLHLPGLADGWWIYLAVYAVFIGIHLSGAGEALRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
MFIITGVALVGLVIFTIGAVGRFDVHNLTNIPVDESARGASAFLPYGYLGIWAAVPFAIW
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFLAIEGVPLAAEEAREPAKNIPRGILMAMLVLVITGTAVLLLVPGVGGAQEMGESGNPL
HHHHHCCCCCCHHHHHCHHHHCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHCCCCCCHH
VEALGTATVAKVVNYIGLSGLIASFFSIVYAYSRQTFALSRAGYLPTGLSVTNGRKAPVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCHH
ALIVPGIVGFLLSLTGEGAMLLNMAVFGAALSYVLMMVSHIVLRIREPEMERPYRTPGGI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ATSGFALVIACVAVVATFIVDTTAAFATFGVFVLFMAYFGLYSRHHLVANSPDEEFAALA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EAENELK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]